Parasite metabolic adaptation in tissue colonization

    • Application Deadline
      Deadline:
      10 December 2020
      (application date has expired)
    • Contact Name
      Contact:
      Luisa Figueiredo


    A 2-year Post-Doc contract is available to join Luisa Figueiredo laboratory at the Instituto
    de Medicina Molecular, in Lisbon. Funding is provided by the ERC (European Research
    Council).

    We are looking for a highly motivated scientist, holding a PhD in life sciences, interested
    in metabolism and host-pathogen interactions. The adipose tissue is a major reservoir
    of African trypanosomes and parasites adapt to living in this tissue by activating fatty
    acid beta-oxidation (Trindade et al., Cell Host and Microbe, 2016). The goal of this project
    is to characterize the metabolic adaptation of trypanosomes to the tissue and understand
    its importance to disease progression in mouse models. Knowledge in biochemistry and
    metabolism is required.

    Position is available from March 2021. The stipend will be determined according to the
    candidate’s experience. This project involves collaborations with other European
    laboratories (Austria, UK and France), which will provide opportunities for occasional
    traveling or short stays abroad.

    Our laboratory is 10-years old and is currently composed of 11 researchers (1 Masters
    student, 5 PhD students, 5 Post-docs), of 4 different nationalities, interested in African
    trypanosomes. We cover a diverse range of projects including different aspects of tissue
    tropism both from the parasite and host perspective, but we are also interested in
    regulation of gene expression by RNA modifications and lncRNAs. Over the years we
    have been funded by Howard Hughes Medical Institute, European Research Council,
    EMBO, La Caixa and FCT.

    Applications should be submitted to Luisa Figueiredo ([email protected]) and
    must include: a motivation letter, a short CV and contacts of two references. Letters of
    reference from qualifying candidates will be requested if necessary. Candidates should
    have first author publication(s) in peer-reviewed international scientific journals.

    Closing date of this call: 10th December 2020.

    Learn about us:
    https://imm.medicina.ulisboa.pt/pt-pt/investigation/laboratories/luisa-figueiredo-lab-2/
    @luisamfigueired


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