8641| metaLinear Ltd| Scientist- Antibiotic Drug Discovery| metaLinear Ltd is new start-up company, using protein and proteome engineering to uncover novel drug targets in pathogenic bacteria.We are currently seeking an exceptional scientific all-rounder who is equally comfortable with molecular biology, protein chemistry, microbiology, protein purification, structural biology, and small molecule drug discovery. If you have a good grounding in at least two of these fields and a strong desire to learn more, we would also like to hear from youCandidates should hold a good degree in a biological science and at least 4 years of relevant post-graduate experience. metaLinear offers a vibrant and dynamic environment. We are family-friendly, and we embrace diversity. metaLinear is located at Alderley Park, AstraZeneca's former R&D site, and benefits from access to state of the art core facilities in beautiful managed parklands.

8632| University of Strathclyde, Smart Materials Research and Device Technology Group, Department of Pure and Applied Chemistry| Postdoctoral Research Associate| Applications are invited for the position of Research Associate in the Department of Pure and Applied Chemistry to join the Smart Materials Research and Device Technology (SMaRDT) group to work for an EPSRC funded project ‘Highly Efficient Elastic Perovskite Solar Cells (HEEPSC)’. As a research associate you will play a key role in this project working with experts from academia (Oxford, Edinburgh and Strathclyde) as well as industry (NSG Pilkington, G24 power, Shadow Robotics and Dupont Teijin films). You will be working closely with Dr. Aruna Ivaturi, who is an EPSRC Fellow, Chancellor’s Fellow and Lecturer leading the SMaRDT group. The main aim is to develop and demonstrate, novel beyond the state-of-art perovskite solar cells with high efficiency and mechanical compliance for integration with robotics.You will have a PhD (or equivalent) in Physics/Material Science/Chemistry/Electrical Engineering, or a closely related field with strong background and extensive experience (industrial or postdoc or PhD level) in Perovskite solar cells fabrication and characterisation and/ Flexible and Elastic Electronics and/ Nano and microelectronics fabrication techniques.You would have the ability to plan, manage, organise and prioritise your own workload and ensure that all activities are completed to deadline to achieve the corresponding deliverables and milestones. You will have excellent interpersonal skills with proven ability to collaborate well with colleagues from academia and industry. You will have excellent communication skills with ability to work independently and as part of a team. A proven ability to published research in high quality journals and present research outcomes at local, national and international research meetings/workshops/conferences is expected.Informal enquiries about the post can be directed to Dr Aruna Ivaturi, [email protected] interviews for this post will be advised in due course.

8631| Massey University, School of Built Environment| Postdoctoral Research Fellow in Construction Management| The School of Built Environment at Massey University (Albany) is seeking to appoint a Postdoctoral Research Fellow in one of its recently formed research groups to provide research assistance in Construction Management for the School of Built Environment. This particular position is for three years, full-time fixed-term, requires a PhD qualification (or very close to completion) and is based at the Auckland campus.In this appointment you will be expected to contribute to the group's research activities and you will have a strong background in areas relevant to one of the research groups in the school. In addition to a strong publication track record, previous experience in preparing competitive grants proposal is desirable.Key success factors include:• active participation in research programme and contribution to the ongoing research activities in Construction Management, particularly in (but not limited to) Offsite Construction/DfMA, Construction Procurement and Earned Value Management or Construction IT and Advanced Technologies• data collection, analysis and dissemination of research findings through publishing papers and other scholarly works in academic journals, books and other appropriate media.Present research and participate at national and international academic conferences• support in the teaching activities for the school and assist in the supervision of students at graduate and post-graduate level as required.For any further information, please contact Professor Monty Sutrisna, Head of the School of Built Environment via email: [email protected] date: 31 August 2019Reference number: CS_CS_397_08/19For further information and to apply online, visit: http://masseyunicareers.nga.net.nz

8627| Massey University, School of Built Environment| Postdoctoral Research Fellow in Indoor Air Quality/ Healthy Building/ Sustainable Building| The School of Built Environment at Massey University (Albany) is seeking to appoint a Postdoctoral Research Fellow in one of its recently formed research groups to provide research assistance in Construction Management for the School of Built Environment.In this appointment you will be expected to contribute to the group’s research activities and you will have a strong background in areas relevant to one of the research groups in the school. In addition to strong publication track record, previous experience in preparing competitive grants proposal is desirable.Key success factors include:• active participation in research programme and contribution to the ongoing research activities in indoor air quality, healthy buildings, sustainable buildings or a related topic• data collection, analysis and dissemination of research findings through publishing papers and other scholarly works in academic journals, books and other appropriate media• present research and participate at national and international academic conferences• support the teaching activities in the school and assist in the supervision of students at graduate and post-graduate level as required by the Head of School.This particular position is for two years, full-time fixed-term, requires a PhD qualification (or very close to completion) and is based at the Auckland campus.For any further information, please contact Professor Monty Sutrisna, Head of the School of Built Environment via email: [email protected] or Professor Robyn Phipps at [email protected] date: 31 August 2019Reference number: CS_CS_394_08/19For further information and to apply online, visit: http://masseyunicareers.nga.net.nz

8625| John Innes Centre, Crop Genetics| Postdoctoral Researcher| Postdoctoral ResearcherApplications are invited for a Postdoctoral Researcher to join the Crop Pathology group at the John Innes Centre, Norwich, UK, to study the impact of globalisation on diseases of arable crops.Background:The post is in the lab of Professor James Brown, which takes an inter-disciplinary approach to studying durable control of crop diseases, including methods of breeding for durable resistance. This is one of several research groups studying diverse aspects of plant pathology, which together make the John Innes Centre an outstanding institute for research on crop diseases.The role:The goal of the project is to understand the impact of current, rapid changes in agriculture on the durability of crop disease resistance. These include globalisation of the plant breeding industry, climate change, and inadvertent dispersal of pathogens by global transport networks. The research will focus on rust diseases of wheat, particularly the genetic diversity of disease resistance, changes in the severity of rust epidemics, and improved control of wheat rusts. The project will be a desk study, combining data from diverse sources in agricultural science, international transport, and climate change. The work will involve collaboration with colleagues at JIC and with partners in an EU Horizon 2020 project, RustWatch.The ideal candidate: Reflecting the interdisciplinary nature of the project, the successful applicant may have a PhD or equivalent experience in agricultural economics, a social science relevant to agriculture, or a relevant discipline within agricultural science. Candidates must be able to define testable hypotheses in social sciences relevant to agriculture, and to identify and use relevant data sources. A high level of expertise in analysing complex data is essential, as are excellent communication skills, both written and oral, including the ability to present complex information with clarity. Knowledge of areas such as agricultural science, particularly plant breeding and plant pathology, international travel and transport, and climate change will be advantageous.Additional information:Salary on appointment will be within the range £31,625 to £38,575 per annum depending on qualifications and experience. This is a full time post for a contract of 30 months.We welcome applications from candidates seeking job-share, part-time or other flexible working arrangements.Interviews will be held on 18 September 2019. For further information and details of how to apply, please visit our web site http://jobs.jic.ac.uk or contact the Human Resources team on 01603 450462 or [email protected] quoting reference 1003753. We are an equal opportunities employer, actively supporting inclusivity and diversity. As a Disability Confident organisation, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. The John Innes Centre is also proud to hold a Gold Award from Athena SWAN and is a member of Stonewall’s Diversity Champions programme.The closing date for applications will be 4 September 2019. The John Innes Centre is a registered charity (No. 223852) grant-aided by the Biotechnology and Biological Sciences Research Council.

8644| UKRI Medical Research Council, Laboratory of Molecular Biology| Postdoctoral Scientist - Structural Studies - Julian Gough - LMB 1148| Postdoctoral Scientist Starting Salary £30,914 - £33,755 per annum 3 year fixed term MRC Laboratory of Molecular Biology, Cambridge, UKWe are looking for a computational postdoctoral scientist to join the group of Prof Julian Gough to work on cell fate and evolution. Specifically, to undertake research to investigate human cell reprogramming. We have created a system ‘Mogrify’ based on cellular networks to predict transcription factors for reprogramming one human cell type into another (Rackham et al. Nature Genetics 2016). This has been experimentally validated by proving several novel conversions, and we are validating many more. There is a great deal more research to do on cell reprogramming, e.g. with regard to: epigenetic factors, down-regulation, different sequencing technologies, sources of network interactions and synthetic cell types. The work will be entirely computational.You are highly motivated, have a PhD in a relevant subject, and you have an aptitude for theoretical work and data analysis. The post is available to applicants with varying computational experience. Applicants with no formal training in computational or mathematical work but who enjoy it, have self-taught to a high level, the aptitude and are keen to learn will be considered, if they have other complimentary biological qualifications, knowledge and experience. Conversely computer or technical scientists with no formal training in molecular biology will be considered if they have a powerful interest and motivation in molecular biology and are driven to learn.The successful applicant will be awarded a 3 year Career Development Fellowship/MRC Postdoctoral Training Scheme. The fellowship is a training and development position for a Postdoctoral Scientist who has recently completed their doctoral studies, or is moving into a new research discipline. The project will include working with AstraZeneca and other biotech companies internationally and in the Cambridge area to translate the technology for medical use and commercialisation.Working for the MRC provides a whole host of benefits including a final salary pension scheme, Benenden Healthcare membership and excellent holiday entitlement. You will also have access to employee shopping/travel discounts, on site sport and social facilities, as well as salary sacrifice cycle to work schemes and childcare vouchers. The MRC Laboratory of Molecular Biology is one of the birthplaces of molecular biology and is an internationally renowned centre for fundamental biomedical research. The LMB has a strong track record in training Postdoctoral Fellows who have gone on to become leading Scientists. We also have an excellent record of innovative basic research leading to applications in medicine. Scientists are drawn to the LMB from all over the world, thus creating a lively and international community for the exchange of ideas and technical innovation. For further information of the research undertaken at the LMB, please visit: http://www2.mrc-lmb.cam.ac.uk Informal enquires may be made to Julian Gough at; [email protected] MRC Laboratory of Molecular Biology is a research institute within UK Research and Innovation (UKRI). UKRI is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at www.ukri.org.Working for UKRI MRC provides a whole host of benefits including:• Defined benefit pension scheme• Excellent holiday entitlement (40 ½ days including bank holidays & privilege days)• Benenden Healthcare membership• Access to employee shopping/travel discounts• On site sport and social facilities• Salary sacrifice cycle to work scheme• Childcare vouchersTo apply and access full details of the vacancy please visit our job board at https://mrc.tal.net/vx/lang-en-GB/appcentre-1/candidate/postings/1285 If you are unable to apply online please contact us at [email protected] date: 17/09/2019Final appointments will be subject to a pre-employment screening.The Medical Research Council is an Equal Opportunities Employer who participates in the Disability Confident scheme.

8628| Massey University, School of Built Environment| Postdoctoral Research Fellow in Resilience/ Disaster Recovery/ Disaster Management/ Climate Change/ Sustainable Development| The School of Built Environment at Massey University (Albany) is seeking to appoint a Postdoctoral Research Fellow in one of its recently formed research groups to provide research assistance in Construction Management for the School of Built Environment.In this appointment you will be expected to contribute to the group's research activities and you will have a strong background in areas relevant to one of the research groups in the school. In addition to strong publication track record, previous experience in preparing competitive grants proposal is desirable.Key success factors include:• active participation in research programme and contribution to the ongoing research activities in Resilience/Disaster Recovery/Disaster management/Climate Change/Sustainable Development or a related topic• data collection, analysis and dissemination of research findings through publishing papers and other scholarly works in academic journals, books and other appropriate media• present research and participate at national and international academic conferences.This particular position is a one year full-time fixed-term, and requires a PhD qualification (or very close to completion) and is based at the Auckland campus.For any further information, please contact Professor Monty Sutrisna, Head of the School of Built Environment via email: [email protected] or Professor Suzanne Wilkinson at [email protected] date: 31 August 2019Reference number: CS_CS_396_08/19For further information and to apply online, visit: http://masseyunicareers.nga.net.nz

8635| Nottingham Trent University, Computing| Research Associate in Pervasive Computing| We have an open position for a Research Associate available at the Smart Sensing Lab, Computing & Technology department, Nottingham Trent University, Nottingham, UK.The position is part of the “Smart Tagging and Proximity Detection for Crime Reduction“ project, in collaboration with the Dawes Centre for Future Crime at UCL.The project aims at utilising the Internet of Things (IoT) for crime prevention and victim support. We are particularly interested in Physical Prototyping using (Near Field communication) NFC tags and Bluetooth Beacons.The successful candidate will work with Dr Kanjo and with Dawe center to conduct research that ranges from software and hardware development to experimental user studies, focus groups and evaluation. Post holder will conduct research in the area of Pervasive Computing, physical and digital prototyping, mobile development, accessibility and participatory design. Experience in mobile development is highly desirable.If you have any specific queries in relation to this position, please contact Prof Assoc Eiman Kanjo, on +(44)1158484820 or via email [email protected] apply please visit: https://vacancies.ntu.ac.uk/displayjob.aspx?jobid=6508Successful applicants will usually be appointed to the base of the advertised salary grade, except in justifiable circumstances.

8618| Maimonides Biomedical Research institute of Cordoba (IMIBIC)| Postdoctoral Fellowhips in Biomedicine| IMIBIC Fellowship Programme for Personalised and Precision Medicine - IMIBIC-P2MedIMIBIC-P2Med offers 6 Postdoctoral Fellowships of up to 3 years at the Maimonides Biomedical Research Institute of Cordoba (IMIBIC, https://www.imibic.org/), in Cordoba, south of Spain.The Official programme website: https://p2med.imibic.orgProgramme Calendar:Call Opens: 1st October 2019Call Closes: 10th Jan 2020Evaluation: January - May 2020Results: June 2020Start of the Fellowhips: June - September 2020Research areas:We welcome applications within the five scientific programmes of IMIBIC:I Active aging and FrailtyII Nutrition and endocrine and metabolic diseasesIII Infectious and immunological diseases and organ transplantationIV Cancer (Oncology and Oncohematology)V Chronic and Inflammatory DiseasesEligibility:The Fellowships are targeted to Recognised Researchers (R2) based on the research profile descriptors of the European Commission (https://tinyurl.com/y4xb8z5b)1) Eligible applicants must be in possession of a PhD or have at least 4 years of full time postgraduate research experience by the call deadline, i.e. 10th January 2020.2) All applicants must comply with the International Mobility Rule: The applicant must not have resided or carried out his/her main activity (work, studies, etc.) in Spain for more than 12 months in the 3 years immediately before the call deadline.How to apply:Applications must be completed and submitted via the Online Application Platform, accessible via the IMIBIC-P2Med website (https://p2med.imibic.org). The Online Application Platform will be available only during the call opening, from October 1st until the call closing, 10th January 2020, midnight CET.Guide for applicants and obligatory application templates are available at https://p2med.imibic.org/application-templates/Employment conditions:The selected Fellows are nominated Marie Skłodowska-Curie Fellows and will be hired through an employment contract with full Social Security coverage, including full health insurance and unemployment benefits.The annual Gross Salary before tax for researchers without family allowance is 34.850 €.The annual Gross Salary before tax for researchers with family allowance is 38.930 €*.Additional 6.630 € per year will be available for research costs of each Fellow.*The family status of the researcher will be determined at the date of deadline of the call (i.e.10 January 2020) and will not be revised during the fellowship.Evaluation and Selection:The selection of the IMIBIC-P2Med Fellows follows an open, transparent, merit based, impartial and equitable selection procedure based on peer review.The process includes the eligibility check of all applications, evaluation of CV and Project proposal, and personal interview.Evaluation criteria:The evaluation criteria for the evaluation of the CV and Project Proposal is:CRITERIA 1: Excellence of the candidate’s CV. Score 0-40.CRITERIA 2: Excellence of the Project proposal. Score 0-60.The maximum score is 100. A threshold of 60 will be applied. Up to 18 best ranked applicants above the threshold will be invited for Personal Interview. The evaluation criteria for the Personal Interview is:CRITERIA 1: Scientific knowledge and skills in the area of interest, understanding of a field of study and mastery of research associated with that field. Score 0-60.CRITERIA 2: Capacity of creative thinking, critical analysis, and synthesis of new and complex ideas. Score 0-20.CRITERIA 3: Presentation and communication skills, ability to explain the expected outcome and value of their research to the research community and also to lay audience. Score 0-20.For detailed information about the evaluation criteria, see: https://p2med.imibic.org/evaluation-criteria/

8638| European Molecular Biology Laboratory (Hamburg)| EMBL Interdisciplinary Postdocs (EIPOD)| The European Molecular Biology Laboratory (EMBL) is one of the top life sciences research institutions in the world. Research is organized into units at the six EMBL sites. The main laboratory in Heidelberg, Germany covers Cell Biology and Biophysics, Developmental Biology, Genome Biology and Structural and Computational Biology.EMBLThe EMBL-EBI in Hinxton, near Cambridge, UK, is specialized in Bioinformatics whereas the EMBL sites in Hamburg, Germany and Grenoble, France focus on Structural Biology. The Rome site focuses on epigenetics and neurobiology. Research at EMBL's newest site in Barcelona focuses on tissue biology and disease modelling.The EIPOD4 programme underlines EMBL's strong commitment to promoting interdisciplinary research. The institution has a long-standing tradition of scientific excellence that builds on highly interactive research between the group leaders of different research units. EIPOD4 projects capitalise on synergies emerging at the borders of overlapping yet separate scientific fields, and involve transferring techniques to a novel context.The programme will offer about 20 positions in 2019. Features of the positions include:Funding for cross-disciplinary projectsThree years' of secure fundingProviding generous health care benefits and pension accessDevelopment of a project proposal forms the basis for recruitmentAdditional partners from academia, industry, clinics and museums are welcomeApplicants are invited to design and propose an interdisciplinary project of their choice according to scientific interest.EIPODs will join the EMBL Postdoctoral Programme with its broad range of advanced training and career development opportunties.ApplicationApplication deadline: September 5th, 2019.Applications should be made online only at www.embl.org/eipod.EIPODs selection is open to all nationalities, the only criteria being scientific excellence and interdisciplinarity.

8617| Institute of Cancer Research, Post-doctoral Training Fellow - Myeloma Molecular Therapy Group| Post-doctoral Training Fellow - Myeloma Molecular Therapy Group| The Institute of Cancer Research is at the forefront of international cancer research and, with the Royal Marsden NHS Trust, forms the largest comprehensive cancer centre in Europe. Professor Richard Houlston FRS and Dr Martin Kaiser are seeking a highly motivated Post-Doctoral Research Fellow to work on projects aiming to provide novel insights into the development of the immune plasma cell cancer multiple myeloma. The focus of the research is the identification and characterisation of genetic variants that influence cancer risk, specifically those that map to non-coding DNA. We are seeking a highly motivated Research Fellow to contribute to our programs of work, combining high-throughput methods (Hi-C, MPRA and CRISPR) with in-depth functional characterisation of risk regions.We wish to appoint an individual with extensive experience of molecular genetics, relevant to disease gene characterisation. We undertake a broad range of genetic experiments including high-throughput sequencing, epigenetic profiling and Hi-C analyses, MPRA and CRISPR.Informal enquiries about on-going projects can be made to Martin Kaiser (tel: 0208 722 4166; e-mail: [email protected]). Please Note - this email address is for enquiries only; applications must be made via the e-Recruitment system via the ICR Website.

8613| University College London, Centre for Computational Science| Research Fellow (Software Engineer for Molecular Simulation)| Full Time: The appointment will be on UCL Grade 7.The salary range will be £35,328 to £42,701 per annum, inclusive of London Allowance.Applications are invited for a Research Fellow/Software Engineer to work with Professor Peter Coveney in the Department of Chemistry at University College London. The successful candidate will join a very active cross-disciplinary group in the Centre for Computational Science. A PhD degree in bio-molecular dynamics modelling for protein-ligand alchemical binding free energy determination is a minimal requirement together with demonstrable ability to programme in more than one high-level language.We are looking for a research software engineer to support our work in computer-based drug discovery and personalised medicine. Our main focus is employing molecular dynamics simulations to investigate origins of drug resistance in pathologies such as HIV, cancer, and antimicrobial resistance. A major focus of this position will be developing automated workflows using the NAMD and OpenMM packages to perform binding free energy calculations. The postholder will be responsible for supporting large simulation campaigns on ultra-high-end supercomputers, including Summit, the number one in the Top 500 list of supercomputers worldwide.The post is funded by the European Commission and is available from 1 September 2019 or soon thereafter, for a period of 24 months initially.The successful candidate must have a PhD (or near to being awarded a PhD) in bio-molecular dynamics modelling for protein-ligand alchemical binding free energy determination, with proven extensive parallel programming expertise in at least two languages (e.g. C++ and Python). They must have experience using common molecular dynamics packages including at least one of NAMD, AMBER, GROMACS and OpenMM. Please note, appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, appointment will be at Research Assistant Grade 6B (salary £30,922 to £32,607 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis.For further details about the vacancy and how to apply online please go to https://www.ucl.ac.uk/human-resources/working-ucl/jobs-ucl and search on Reference Number Number 1816446Please include a publication list along with CV.Informal enquiries should be addressed to Prof Peter Coveney ( [email protected] ). Any queries on the application process can be directed to Judith James - [email protected] Date: 25th August 2019Latest time for the submission of applications: 23:59.Interview Date: TBCWe particularly welcome female applicants and those from an ethnic minority, as they are under-represented within UCL at this level.Our department holds an Athena SWAN Bronze award, in recognition of our commitment to advancing gender equality.To apply click here https://atsv7.wcn.co.uk/search_engine/jobs.cgi?owner=5041178&ownertype=fair&jcode=1816446

8645| Chonnam National University, School of Mechanical Engineering| Postdoc Researcher for Shape Memory Polymers| We are looking for an outstanding post-doc researcher who is able to synthesize “Shape memory polymers” completely by him- or herself and has good ability of writing English paper for high quality international Journal.A researcher who has the background and experiences in- Shape memory polymers- Synthesizing comonomers using various monomers- Chemical, Optical, Mechanical characterization of the fabricated gels- Chemistry, Chemical Engineering, Polymer chemistry or Polymer physicsare welcomed.Until this time, we published papers in Advanced Materials (I.F.: 25.809), Materials Horizons (I.F.: 14.356), Water research (I.F.: 7.913), Chemical Engineering Journal (I.F.: 8.355), ACS Applied Materials and Interfaces (I.F.: 8.456), Soft Matters (I.F.: 3.399) (Please see https://scholar.google.co.kr/citations?hl=ko&user=Hup8d38AAAAJ&view_op=list_works&sortby=pubdate).At the first contracted year, the researcher will receive 3,200,000 KRW/month as a salary, 3,200,000 KRW/year as a discharge allowance, and some amount of incentive.The work will start from the end of September, 2019. Interested researchers are encouraged to apply their Curriculum Vitae to the email address below:Insu Jeon, ProfessorSchool of Mechanical EngineeringChonnam National University77 Yongbong-ro, Buk-gu, Gwangju, 61186, Republic of KoreaTel. : +82-62-530-1688Fax. : +82-62-530-1689e-mail : [email protected], [email protected]

8642| UKRI Medical Research Council, Laboratory of Molecular Biology| Postdoctoral Scientist - Structural Studies - John Briggs - LMB 1146| Postdoctoral Scientist/CDF Starting Salary £30,914 - £33,755 per annum 3 years fixed termMRC Laboratory of Molecular Biology, Cambridge, UKWe wish to recruit a Postdoctoral Scientist/CDF to develop, improve and apply methods for cryo-electron tomography and computational image analysis by subtomogram averaging. The successful candidate will undertake independent scientific/technical research into new and improved methods for cryo-electron tomography within the research group of Dr John Briggs, and implement these methods using instrumentation within the world-leading electron microscopy facility at the MRC Laboratory of Molecular Biology in Cambridge, UK. The principal aim of Dr Briggs’ research group is the development and application of electron microscopy methods within a research programme aimed at structural and mechanistic studies of the assembly, maturation and fusion of enveloped viruses and coated vesicles.The LMB has a large and vibrant cryo-EM community and the successful candidate will collaborate with members of the Briggs and Scheres groups, staff in the EM facility and other cryo-EM researchers at the LMB. The EM facility at the LMB contains ten electron microscopes including three Titan Krios microscopes as well as a suite of associated equipment for sample preparation. The MRC-LMB has extensive resources for high-performance computing including large CPU and GPU clusters.The successful candidate’s main duties will include: • Undertaking independent scientific research aimed at developing and optimizing methods and pipelines for experimental cryo-electron tomography as well as computational image processing by subtomogram averaging; • Together with other members of the research group, applying improved methods to research fusion mechanisms of enveloped viruses and coated vesicles; • Sharing expertise and research results by collaborating with other users and staff performing cryo-electron tomography or image analysis within the LMB.A relevant PhD degree, excellent communication skills, substantial experience with electron microscopy, and the ability to independently carry out a scientific/technical experimental research programme, are essential. This role may be appropriate for a person interested in a future career in methods development research, or in technical support/management.The successful applicant will be awarded a three year Career Development Fellowship / Postdoctoral training Scheme position. This is a training and development position for a post-doctoral scientist who has recently completed their doctoral studies, is moving into a new research discipline or has limited experience of key transferable skills. The MRC LMB has excellent scientific core facilities and training opportunities.The MRC Laboratory of Molecular Biology is a research institute within UK Research and Innovation (UKRI). UKRI is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at www.ukri.org.Working for UKRI MRC provides a whole host of benefits including:• Defined benefit pension scheme• Excellent holiday entitlement (40 ½ days including bank holidays & privilege days)• Benenden Healthcare membership• Access to employee shopping/travel discounts• On site sport and social facilities• Salary sacrifice cycle to work scheme• Childcare vouchersTo apply and access full details of the vacancy please visit our job board at https://mrc.tal.net/vx/lang-en-GB/appcentre-1/candidate/postings/1284 If you are unable to apply online please contact us at [email protected] date: 12 September 2019 Final appointments will be subject to a pre-employment screening.The Medical Research Council is an Equal Opportunities Employer who participates in the Disability Confident scheme.

8612| Institute of Cancer Research, Genetics and Epidemiology| Postdoctoral Training Fellow in Molecular and Population Genetics| Professor Richard Houlston FRS and Dr Martin Kaiser are currently recruiting two Myeloma UK funded Research Fellows (Postdoctoral) to work on projects aiming to gain new insights into the inherited and acquired sequence changes influencing the development of the immune plasma cell cancer multiple myeloma. We are looking for highly motivated Research Fellows with an interest in human cancer and in generation of large-scale omics data and gene-editing screens. We wish to appoint an individual with extensive experience of molecular genetics, relevant to disease gene characterisation. We undertake a broad range of genetic experiments including high-throughput sequencing, epigenetic profiling and Hi-C analyses, MPRA and CRISPR.The successful candidate will join a vibrant research group on the identification and characterisation of cancer genes. We work on haematological cancers but also have on-going projects on other tumours. The recent publications, illustrating the scope of our work - Nat Genet 2018;50:1375; Blood Adv 2019;3:21; Nat Commun 2015;6:6178. Cancer Res. 2019 Feb 1. pii: canres.2888.2018. Nat Genet. 2017;49:789.We implement multiple different molecular strategies to translate genetics to tumour biology including high-throughput sequencing, epigenetic profiling and Hi-C analyses, MPRA and CRISPR. There is strong bioinformatics/statistical support within the group.The post holder would be expected to bring genetic research experience to development of experimental design and implementation of projects and will be expected to interact with, and supervise, junior team members, together with other senior researchers.Informal enquiries about on-going projects can be made to Richard Houlston ([email protected]) or Martin Kaiser ([email protected]). Please Note - these emails are for enquiries only; formal applications must be submitted online.

8636| University College Dublin, School of Medicine| UCD Post-doctoral Research Fellow Level 2 REF 011714| "Reactive oxygen species disruption of bacterial tyrosine phosphorylation alters the functional ecology of the intestinal microbiome in inflammatory bowel disease"This project will examine the effect of reactive oxygen species on individual constituents of the faecal microflora. The successful candidate will lead a three year project that aims to isolate, identify and characterise the effects of excess reactive oxygen species on individual core microbial constituents of intestinal samples from children with inflammatory bowel disease. This is an advanced research focused role, building on your prior experience as a post-doctoral fellow, where you will conduct a specified programme of research supported by research training under the supervision and direction of a Principal Investigator. The primary purpose of the role is to develop new or advanced research skills and competences, on the processes of publication in peer-reviewed academic publications and scholarly dissemination, the development of funding proposals, and the supervision and mentorship of graduate students along with the opportunity to develop your skills in research led teaching.In addition to the Principal Duties and Responsibilities listed below, the successful candidate will also carry out the following duties specific to this project:• Isolate and identify, using flow cytometry, tyrosine phosphorylation patterns of individual members of fecal microflora • Compare tyrosine phosphorylation patterns between microflora from normal children, those with active inflammatory bowel disease (IBD) and those with IBD in medical remission• Determine the phosphoproteomes of dominent members of the fecal microflora and how they are altered on exposure to reactive oxygen species

8630| Quadram Institute Bioscience, Food Databanks National Capability| Research Scientist (Food and Nutrition Data Scientist)| We are looking for a highly motivated individual to drive food data analytics within the Food Databanks National Capability (https://fdnc.quadram.ac.uk/) at the Quadram Institute (QI), with an interest in embracing cutting edge computational tools in the study of food composition, food intake and wider nutritional research. About Food Databanks National Capability:Food Databanks National Capability (FDNC) compiles and publishes data on the composition of foods eaten in the UK, which is utilised by a wide range of stakeholders from a variety of disciplines, and underpins research in food, nutrition and health. This includes the government’s National Diet and Nutrition Survey, which is used to inform public health policy. We are additionally responsible for developing and maintaining eBASIS, a database of non-nutrient plant-derived bioactive compounds with putative health benefits in foods. eBASIS provides information from published literature about bioactives with putative health benefits, or detrimental effects in humans, supported by peer-reviewed evidence.The FDNC team is active in participating and leading a succession of UK- and EU-funded projects and consortia around diet and health. We are currently leading an EIT Food activity around personalised nutrition services and are one of the lead partners in a consortium to develop an EU-wide Food, Nutrition Security (FNS) Data Cloud (FNS-Cloud, 2019-2023) to connect various types of data relevant for the food and health research community. We also work closely with QI research groups and our Norwich Research Park partners – the University of East Anglia and the Norfolk and Norwich University Hospital – that share an active interest in nutrition, and are involved in human studies to understand the interplay between the gut microbiome and nutrition.The role:This exciting role will involve two main activities:1) Establishing predictive analytics through machine learning and deep learning, using existing and novel data (including food composition and intake data, food imagery, consumer behaviour and lifestyle, biological measurements from blood and wearables, and gut microbiome) that are being generated from the FDNC team and our collaborators. This work will underpin our activities as a lead partner in the EU-wide Food, Nutrition Security (FNS) data cloud to connect various types of data relevant for the food and health research community, and importantly will provide opportunities for the post-holder to work closely with our data science partners across Europe around food and health data.2) Managing and upgrading our bioactives database (eBASIS) to improve functionality and accessibility, and will explore opportunities to automate the process of data entry (e.g. text mining).The ideal candidate:This post will be well suited to a PhD graduate in Data Science/Computational Science, with an interest in nutrition. Candidates should possess prior experience with Python/C++ programming and excellent knowledge of a variety of machine learning techniques (e.g. clustering, decision tree learning, neural networks, deep learning). Strong skills in advanced statistics are essential, as are demonstrable examples of applying machine learning algorithms for data analysis, preferably but not exclusively in areas related to food and nutrition.Additional information:Salary on appointment will be within the range £31,625 to £38,575 per annum depending on qualifications and experience. This is a fulltime contract for a period of 30 months. For further information and details of how to apply, please visit our web site https://jobs.quadram.ac.uk or contact the Human Resources team on 01603 450462 or [email protected] quoting reference 1003758.We are committed to equal opportunities and welcome applications from all sectors of society. The Institute supports equality of opportunity within the workplace and expects all employees to share and display these values. To support our commitment, we have a range of family, faith and diversity friendly working arrangements to help all staff achieve excellence in their area of work.As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. About the Quadram Institute:The Quadram Institute is a new interdisciplinary research institute at the forefront of a new era in food and health research. Its mission is to understand how food and the gut microbiota are linked to the promotion of health and the prevention of disease. A partnership between Quadram Institute Bioscience, the University of East Anglia, the Norfolk and Norwich University Hospital and BBSRC, it brings together scientists and clinicians in a new state-of-the-art building. The Quadram Institute is based on the Norwich Research Park, one of Europe’s largest centres of life sciences and home of the John Innes Centre and The Earlham Institute.

8603| University of Munich, Institute of Cardiovascular Prevention| The Institute for Cardiovascular Prevention invites applications for a Postdoc Position| To study the role of chemokine receptors CCRB, CXCR4 and ACKR1 in chronic inflammation. Individuals of African ancestry for example carry a variant for ACKR1 which leads to its lack of expression and an alternative pattern of hematopoiesis. This also includes changes in other chemokine receptors. Using atherosclerosis as a disease model for chronic inflammation, the project will interroggate the cell-specific (neutrophils, monocytes and dendritic cells) and systemix effects of these receptors in inflammatory responses in atherogenesis and atheroprogression in mouse models and human samples. The postdoc position is part of the SFB 1123 and therefore offers excellent scientific collaborations. Our RequirementsEligible candidates should have experience with mouse models, immunological and molecular biological techniques, a strong motivation and team spirit. Solid English skills written and spoken are mandatory. The successful candidate should hold an above average PhD degree in biological sciences or related fields and have experience with basic method of molecular and cellular biology. The postdoc will work at the institute of cardiovascular prevention at LMU Munich, Germany Our OfferThe applicant will work in a group of experienced staff, PhD students, postdocs and technicians with excellent infrastructure. Salary will be according to TV-L; the position is funded for up to three years. Applications from severely handicapped persons with basically similar qualifications will be given priority. Presentation and travelling costs unfortunately cannot be refunded. Interested Candidates should submit their electronic application using the reference number 2019-k-0354 including motivvation letter, CV publication list and references to Mr Johan Duchene: [email protected]

8623| University College Dublin, School of Medicine/Charles Institute of Dermatology| 011722 – External Ad - UCD Post-doctoral Research Fellow Level 1, UCD School of Medicine/Charles Institute of Dermatology (36 months)| Applications are invited for a UCD Post-doctoral Research Fellow Level 1 post within UCD School of Medicine/Charles Institute of Dermatology.The UCD Charles Institute of Dermatology has an ongoing research programme led by Prof. Des Tobin to investigate the biology of hair growth. Applications are invited for a 3-year Postdoctoral research position to conduct a specified programme of research under the supervision and direction of Prof. Des Tobin.The primary purpose of the role is to examine the triggers for auto-inflammatory events in the complex immune-mediated non-scarring hair loss disorder Alopecia Areata. Specifically, the project will be focused on the identification of so-called auto-antigens to which the immune system in patients with Alopecia areata appears to be inappropriately directed. Knowledge and research experience of both humoral and cell-mediated immunology in the context of autoimmune disease is expected. Candidates with laboratory research experience using human skin are preferred. For detection and identification of disease-relevant autoantigens, a range of biomedical techniques will be employed both for autoantibodies and autoreactive T cell populations using blood and tissues. Candidates will have excellent current knowledge of the literature in the field; maintain accurate and comprehensive experimental records with excellent attention to detail; assist in preparing presentations and reports as required; maintain laboratory equipment and facilities, and other duties associated with the research project, of an occasional nature, which may be assigned by the Principal Investigator, Prof. Des Tobin.Informal Enquiries ONLY to: Name: Prof Desmond Tobin Title: Professor of Dermatological Science Email address: [email protected] Doc Level 1 Salary Scale: €37,223-€41,827 per annum. Appointment on the above range will be dependent on qualifications and experience.Closing date: 17:00hrs (local Irish time) on 31st October 2019.Applications must be submitted by the closing date and time specified. Any applications which are still in progress at the closing time of 17:00hrs (Local Irish Time) on the specified closing date will be cancelled automatically by the system. UCD are unable to accept late applications.Prior to application, further information (including application procedure) should be obtained from the Work at UCD website: https://www.ucd.ie/workatucd/jobs/ UCD do not require assistance from Recruitment Agencies. Any CV's submitted by Recruitment Agencies will be returned.

8604| The Cancer Research UK Manchester Institute, The Cancer Research UK Manchester Institute| Postdoctoral Scientist – Prostate Oncobiology| • Salary within the range of £31,604 - £41,929 per annum (dependent upon qualifications and experience)• Job Ref: MI/18/104_4• Duration: Fixed term for 3 yearsAbout the role:We are looking for a highly-motivated Postdoctoral Scientist to join Dr Baena’s Prostate Oncobiology group to study the role of inflammation on prostate tumour initiation and how to prevent their progression to metastatic prostate cancer.Prostate cancer (PCa) is the second leading cause of cancer-related mortality in men worldwide, accounting for 15% of all male cancer deaths. PCa patients exhibit a high heterogeneity both clinically and biologically highly variable clinical behaviour; some have indolent disease whilst in others it is lethal. Although the initial response to androgen deprivation therapy is almost universal, progression to castration resistant state is inevitable and lethal. Previous work from our laboratory shows the importance of detailed understanding cellular and molecular events leading to castration-resistant prostate cancer as they’re key for the development of improved therapies for such patients (Barros-Silva et al., 2018; Parry et al., 2019; Baena et al., 2013). The initiation and maintenance of tumour cells rely largely on their ability to interact with and adapt to changes in their primary and metastatic microenvironments. Therefore, the post holder will work on defining how tumour-stem cell promote castration-resistant stage by modifying its local microenvironment. This study will provide new avenues to prevent prostate tumour progression and metastasis by coupling anti-tumour and anti-microenvironment (i.e. immune) interventions for prostate cancer patients.About you:You will have a PhD in a relevant related subject and have research laboratory experience. You will also have profound knowledge in cellular and molecular biology and have experience of working with in vivo cancer models. You will have significant experience of cell culture, particularly in vitro 3D culture systems and handling primary cells. Profound experience in FACS analyses and lineage tracing work is also essential for this position. This is an exciting opportunity for you to be involved in developing and driving the project as well as writing up work for presentation and publication. Why choose Cancer Research UK Manchester Institute?The Cancer Research UK Manchester Institute (www.cruk.manchester.ac.uk), an Institute of The University of Manchester (www.manchester.ac.uk), is a world-leading centre for excellence in cancer research. The Institute is core funded by Cancer Research UK (www.cancerresearchuk.org), the largest independent cancer research organisation in the world. We are currently situated at the internationally-renowned life sciences campus at Alderley Park in Cheshire England, 15 miles from Manchester, a vibrant and dynamic city surrounded by beautiful countryside. We are partnered with The Christie NHS Foundation Trust (adjacent to the CRUK Manchester Institute, Paterson Building) in South Manchester (www.christie.nhs.uk), one of the largest cancer treatment centres in Europe. The CRUK Manchester Institute is a key part of the Belfast-Manchester Movember Centre of Excellence for Prostate Cancer. As well as bringing together expert researchers and clinicians, the Movember Centres of Excellence will also provide a world-class training ground for the scientists of the future, building a legacy of top prostate cancer researchers in the UK, as well as establishing international collaborations for the brightest minds to tackle the most important questions in prostate cancer research – now and into the future.How to apply?To apply for this position please visit our website: https://www.cruk.manchester.ac.uk/recruitment/candidate/searchvacanciesFor any informal enquiries about this post, please contact Dr Esther Baena, email: [email protected] deadline for receipt of applications is: Thursday 05 September 2019.

8621| University of Canterbury, Department of Civil and Natural Resources Engineering| Post-Doctoral Fellow| • Full-time at 37.5 hours per week (1.0 FTE)• 2 Year fixed term opportunityWhat You Will DoWe have an exciting opportunity for a postdoctoral fellow to undertake research in the field of transportation engineering. You will have the opportunity to drive research in a broad range of areas, contributing to the on-going research in the pavement design, numerical modelling and material characterisations.While the primary focus of this position is on research, you will also contribute to teaching of Transportation Engineering courses that support the Master of Civil Engineering.Who You AreYou will have a PhD in Civil Engineering, ideally with a specialisation in Pavement design and materials or a related discipline, as well as advanced research background in bituminous material characterisation and numerical modelling. You will have significant experience with laboratory preparations, testing and instrumentations of asphalt mixes, bitumen and polymer modified rheology with full understandings of the standard tests protocols. You will have a strong background in fracture mechanics, constitutive models, viscoelastic behaviour of asphalt mixes with experience in finite element (FEM), discrete element modelling (DEM) or Smoothed-particle hydrodynamics, SPH. It is also important to have significant experience with software packages such as ABAQUS, PFC3D and have an ability to write and develop user defined material subroutines to be used with Abaqus or other packages for numerical simulations. Additionally, you will have a strong background in statistical analysis as well as an ability to use Matlab and other programming languages such as C++ and visual basic.You will have demonstrated experience of excellent research capabilities (design and leadership) required to carry out innovative and insightful research and a publication track record as well as experience with preparation and delivery of quality oral presentations.Who You Will Work WithThe role of the Department of Civil and Natural Resources Engineering (CNRE) is to remain at the forefront of research and technology and preserve our strong international reputation for high quality teaching.We aim to constantly develop our alumni and industry partnerships, to provide students with the highest level of training, and to expand the scope of our research expertise by attracting and retaining highly-skilled academic and support staff.For more about the Department, please visit: https://www.canterbury.ac.nz/engineering/schools/cnre/Why UCThe University of Canterbury is committed to promoting a world-class learning environment through research and teaching excellence, and has a vision statement of "People Prepared to Make a Difference". You will have the opportunity to work alongside members of a diverse academic community and enrich your own professional and personal development.For information about the range of fantastic benefits that UC offers including flexible work practices, study opportunities and generous superannuation and leave provisions, please visit us: http://www.canterbury.ac.nz/joinusThe closing date for this position is: Sunday, 8th September 2019 (Midnight NZ time) ApplyApplications for this position are submitted online and should include a cover letter (describing background, suitability for the position, your recent and future research projects), a curriculum vitae which includes a list of relevant research publications, and the names and contact details of two referees. Please ensure your application is uploaded as a single pdf file and that the file name is your surname only. We are happy to answer your queries in relation to the application process, please forward these to [email protected] further information specifically about the role, please contact Associate Professor Mofreh Saleh, [email protected] University of Canterbury is an EEO employer and actively seeks to meet its obligation under the Treaty of Waitangi.

8639| University College London, UCL Cancer Institute| Research Fellow in Computational Biology| The appointment will be on UCL Grade 7. The salary range will be £35,328 - £42,701 per annum , inclusive of London Allowance.We are seeking a creative and self-motivated computational biologist to work on glioblastoma invasion for the Neurogenesis and Brain Cancer group, which focuses on glioblastoma invasion and the role that the brain microenvironment plays in this process. The main aim of the project is to investigate the molecular signatures of invading glioblastoma cells and determine how underlying tumour genetics and cell-cell interactions drive invasive mechanisms using novel glioblastoma mouse models that recapitulate the human disease. The post holder will be expected to contribute to all phases of the project life cycle, from study design to publication and be able to identify and apply the most suitable computational methods to be used in the research project. The post holder will collaborate closely with other members of the team and be responsible for the analysis and interpretation of RNA-, exome and ChiP-sequencing data from single and bulk tumour cells. This post is advertised for 1 year initially with the possibility of extension. The successful candidate must have, or be studying towards, a PhD or possess equivalent experience. Appointment at Grade 7 is dependent upon having been awarded a PhD; if it is not the case, initial appointment will be at research assistant Grade 6B (salary £30,922 - £32,607 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis. Demonstrable research experience in bioinformatics and a proven ability to deliver high-quality scientific outputs is essential. The successful candidate must be proficient in R and one of the following programming languages: C++, Perl, Python, and have sufficient expertise in statistical analysis. Experience in analysis of high throughput RNA-sequencing data is essential, experience in single cell analysis an advantage. The applicant should demonstrate an ability and willingness to work collaboratively with basic research scientists. For further details about the vacancy and how to apply online please go to https://www.ucl.ac.uk/human-resources/working-ucl/jobs-ucl search on Reference Number 1812262For enquiries regarding the application process please contact Cancer Institute HR Office [email protected] Closing Date: 14 September 2019Latest time for the submission of applications: 23:59.Interview Date: TBCUCL Taking Action for Equality: our department holds an Athena SWAN Silver award, in recognition of our commitment and demonstrable impact in advancing gender equality.To apply click here: https://atsv7.wcn.co.uk/saf/login.cgi?owner=5041178&ownertype=fair&jcode=1812262&external=246637

8626| University of Warwick, The Elementary Particle Physics Group| Research Fellow x 2 - Deep Underground Neutrino experiment (DUNE)| The Elementary Particle Physics Group at the University of Warwick seeks to appoint two outstanding individuals to join its research programme, working on the Deep Underground Neutrino experiment (DUNE). The Warwick group has a leading role in the development of algorithms to reconstruct neutrino interactions in liquid-argon time-projection chambers. These new research fellowships have been created to help deliver fully-optimised reconstruction solutions for the DUNE experiment through the construction phase of the project.Both research fellows will join the group led by Dr. John Marshall, and their work will involve the design and implementation of sophisticated pattern-recognition algorithms using the Pandora software package. The focus of the two research fellows will be subtly different:• The first research fellow will design and implement algorithms to reconstruct the complex neutrino interaction topologies anticipated at DUNE, exploiting novel Pandora functionality.• The second research fellow will use machine learning, and the latest deep learning approaches, to drive key pattern-recognition decisions within the Pandora algorithms for DUNE.The successful candidates will be expected to hold a PhD in particle physics, or another relevant discipline, and to possess the important computing and technical skills necessary to make significant contributions to our work in these projects.If you have not yet been awarded your PhD but are near submission or have recently submitted your PhD, any offers of employment will be made as Research Assistant on level 5 of the University grade structure (£29,515). Upon successful award of your PhD and evidence of this fact, you will be promoted to Research Fellow on the first point of level 6 of the University grade structure (£30,395 pa).The positions will be awarded for a three year duration in the first instance to start not before October 1st 2019.For further project details please contact:Dr John Marshall: [email protected] (+44-24761-50356)For general enquiries please contact the Head of Group:Prof Gary Barker: [email protected] (+44-24765-23399)Fixed Term, Full-Time Contract for 3 Years, with the possibility of further extension36.5 hours per week (100% FTE)To apply, please visit: https://atsv7.wcn.co.uk/search_engine/jobs.cgi?owner=5062452&ownertype=fair&jcode=1819270&vt_template=1457&adminview=1Closing Date: 1 September 2019The University Values Diversity

8622| University of Grenoble Alpes, Institut de Biologie Structurale| Postdoc position in the structural biology of post-meiotic chromatin| The mammalian genome undergoes a dramatic compaction and reorganization after meiosis that involves the nearly genome-wide eviction of histones and their replacement by transition proteins and protamines. Despite its crucial importance for the mammalian life cycle, post-meiotic genome reorganization remains poorly understood. This project aims at the detailed molecular and structural characterization of the post-meiotic transitional states that occur as nucleosomes are transformed into nucleoproteins.The postdoctoral researcher will use a biophysical and structural approach to study the transitional states that appear in post-meiotic haploid cells (See Barral et al., Mol Cell 2017 66:89-101). The work will include purifying endogenous macromolecular complexes from mammalian cells as well as reconstituting complexes using recombinantly expressed proteins, and subsequently using this material for biophysical analyses and for low- and high-resolution 3D structure determination, including crystallography and cryo-EM. The research will be carried out in the laboratory of Carlo Petosa at the IBS in close collaboration with the laboratory of Saadi Khochbin at the Institute for Advanced Biosciences.Candidates should have a PhD in Biochemistry, Structural Biology or related discipline, or should expect to receive such a degree in the near future. The ideal candidate will have a strong background in biochemistry, protein purification and molecular biology and be experienced in either X-ray crystallography or cryo-EM.Interested candidates should submit a detailed CV (including contact details for references) and a letter of motivation via the web link provided.

8611| John Innes Centre, Biological Chemistry| Postdoctoral Researcher| Applications are invited for a Postdoctoral Researcher to join the Laboratory of Dr Janneke Balk at the John Innes Centre based in Norwich, UK.Background:The group of Janneke Balk is interested in iron homeostasis in plants, with a focus on iron cofactors and intracellular transporters. We use genetics, cell biology and biochemical approaches to understand the function of proteins involved in basic processes, such as mitochondrial respiration and nitrogen fixation. The basic knowledge we gain can be used for improving plant nutrition, including enhancing the iron levels in plant foods through molecular breeding, a process known as biofortification. We work closely together with the group of Cristobal Uauy on increasing iron in wheat grain (Connorton et al., Plant Physiol 174, 2434-44), and collaborate with Hong-Qing Ling in the Institute of Genetics and Developmental Biology, Beijing, on putative iron-sensing proteins (Rodriguez-Celma et al., Proc Natl Acad Sci USA in press).The role:The Postdoctoral Researcher will enhance our research programme on iron biofortification of wheat, in which we are exploring different approaches, GM and non-GM, to increase iron in the white flour fraction. The project addresses fundamental questions of iron distribution and transport in developing wheat grains and aims to identify novel genes in these processes. The successful candidate will prepare samples for RNA-seq and analyse the results, followed by selection of genes regulated by iron for functional studies in yeast and Arabidopsis. They will also investigate newly developed wheat lines for changes in iron distribution and the levels of endogenous iron chelators. The ideal candidate:Candidates should have a PhD in Biology, Biochemistry or a related discipline, with previous experience in carrying out laboratory research in standard molecular biology techniques and bioinformatics. Experience with chromatography (HPLC) is also desirable. Good communication in English and organisational skills with the ability to work independently is essential. Additional information:Salary on appointment will be within the range £31,625 to £38,575 per annum depending on qualifications and experience. This is a full time post for a contract of 18 months, starting 1 October 2019, and is a collaboration between the labs of Janneke Balk and Cristobal Uauy at the John Innes Centre, Norwich, and Hong-Qing Ling at the Institute of Genetics and Developmental Biology in Beijing.For further information and details of how to apply, please visit our web site http://jobs.jic.ac.uk or contact the Human Resources team on 01603 450462 or [email protected] quoting reference 1003742.We are an equal opportunities employer, actively supporting inclusivity and diversity. As a Disability Confident organisation, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. The John Innes Centre is also proud to hold a Gold Award from Athena SWAN and is a member of Stonewall’s Diversity Champions programme.

8640| University College London, Department of Clinical, Educational and Health Psychology| Genetically informed designs for causal inference in mental health and education| Applications are invited for Research Fellows in the Research Department of Clinical, Educational and Health Psychology at University College London (UCL).Position provide an exciting opportunity to join a research project aiming to further our understanding of the aetiology of child and adolescent mental health and educational outcomes. The project features data from major longitudinal cohorts and the application of advanced genetically informed causal inference designs. We are looking for an outstanding, high-potential, early-career researcher to contribute to the success of the project and make a substantial contribution to research in this area. The post-holder will benefit from an outstanding research environment in one of the world’s most prestigious universities, with great opportunities to gain training in cutting-edge longitudinal and genetic methods, and to extend their network of collaborators nationally and internationally.Key RequirementsThe ideal candidate must have a PhD (or be in the process of completing their PhD) in a relevant subject area (e.g. genomics, psychiatric genetics or epidemiological and developmental psychiatry), possess excellent statistical modelling skills and, ideally, knowledge of genetic methods and software, and have a record of high quality publications.Further Details can be obtained on UCL website at bit.ly/30BDlOd and bit.ly/2Y4GmZY

8629| Quadram Institute Bioscience, Food Innovation and Health| Research Assistant (Gut Carbohydrate Fermentation)| Applications are invited for a Research Assistant to join the Laboratory of Dr Fred Warren in the Food Innovation and Health Programme at Quadram Institute Bioscience (QIB), based in Norwich, UK.Background:The Food Innovation and Health Programme is focussed on understanding how individual foods and diets can help us to maintain and improve our health, and developing innovative foods that promote healthy ageing.The role:The Research Assistant will assist with ongoing experiments in the Warren lab using the colon model system. In particular, these will be continuing the lab’s main focus through our BBSRC ISP grant on carrying out colon model experiments using a wide range of starches from different sources as substrates within the model colon system based at QIB. This will require the post holder to set up and run the model colon system. This will be followed by metabolite analysis using 1H NMR, which the post holder will be expected to assist with, both preparing samples and subsequent analysis. The post holder will also be expected to carry out DNA extraction for subsequent 16S sequencing. Additionally, the post holder will assist with starch structural analysis methods including size exclusion chromatography and differential scanning calorimetry for analysis of substrates.The ideal candidate:We are looking to hire a Research Assistant with at a minimum a BSc in a biological sciences subject, preferably also with a higher degree, to assist with our ongoing research projects. We are looking for an enthusiastic and dedicated team member with a passion for linking structure and composition of foods to the microbiome and health outcomes.Applicants should have Excellent time management and organisational skills. Previous experience with batch fermentation/colonic systems, microbiological techniques/anaerobic culture methods and handling human samples is desirable. Additional information:Salary on appointment will be within the range £24,815 to £30,270 per annum depending on qualifications and experience. This is a full time post for a contract of 8 months.For further information and details of how to apply, please visit our web site https://jobs.quadram.ac.uk or contact the Human Resources team on 01603 450462 or [email protected] quoting reference 1003756.Interviews will be held on 18 September 2019. Please note, this post does not meet UKVI requirements to provide Tier 2 visa sponsorship. We are committed to equal opportunities and welcome applications from all sectors of society. The Institute supports equality of opportunity within the workplace and expects all employees to share and display these values. To support our commitment, we have a range of family, faith and diversity friendly working arrangements to help all staff achieve excellence in their area of work.As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. About the Quadram Institute:The Quadram Institute is a new interdisciplinary research institute at the forefront of a new era in food and health research. Its mission is to understand how food and the gut microbiota are linked to the promotion of health and the prevention of disease. A partnership between Quadram Institute Bioscience, the University of East Anglia, the Norfolk and Norwich University Hospital and BBSRC, it brings together scientists and clinicians in a new state-of-the-art building. The Quadram Institute is based on the Norwich Research Park, one of Europe’s largest centres of life sciences and home of the John Innes Centre and The Earlham Institute. (https://quadram.ac.uk/).The closing date for applications will be 5 September 2019. The Quadram Institute Bioscience is a registered charity (No. 1058499) and is an Equal Opportunities Employer.

8634| Northeastern University| Postdoctoral Research Associate| The Health Technology Lab (www.northeastern.edu/healthtech/) at Northeastern University, Boston, MA, is looking to hire one postdoctoral research fellow with strong interest and competency in behavioral interventions using technology (e.g. video games, apps, etc.), with a special emphasis on physical activity and child obesity intervention.The Lab provides an intellectually vibrant scientific environment for researchers and scientists who study the persuasive mechanisms of media and communication technologies and their health, behavioral and psychological applications. We are currently funded by the National Institutes of Health to conduct a 5-year study on the use of active video games to encourage children to increase their physical activity levels.The primary objective of the position is to conduct and coordinate research in physical activity intervention using exercise science methods. The fellow will join an interdisciplinary team of researchers (including communication and behavioral scientists, medical doctors, kinesiologists, psychologists, computer scientists, and biostatisticians) and be involved in all aspects of the research process. Opportunities include having access to data sets for publications, developing and writing research grant proposals, participation in providing academic mentorship of undergraduate and graduate students and research staff, dissemination of research findings at professional conferences, and career development resources through Northeastern University and the Greater Boston area. The postdoctoral associate will also have access to the facilities within and beyond the Lab, including the new Bioimaging Research Center in the Interdisciplinary Science and Engineering Complex (http://www.northeastern.edu/isec/).The fellow is also expected to coordinate one or more of the lab’s ongoing research projects and initiate independent research projects pending satisfactory project coordination. Depending on the need from the university, the candidate may also have the opportunity to serve as the instructor of record for additional compensation.A Ph.D. in exercise science, kinesiology, exercise physiology, behavioral science, health behavior, or a related field is required by the start date of the position. Excellent interpersonal, verbal and written communication skills, attention to details, as well as training in health behavior intervention, research methodology, and quantitative data analysis are essential to the successful candidate. Proposal preparations for sponsored research funding, research experience involving children, and project management experience are pluses. Initial appointments are for a one-year period, with the possibility for renewal, contingent on performance. Salary and benefits are competitive.Applicants should send a letter of application addressing the selection criteria and indicating how their background and expertise fit with the specific needs of the Lab, a curriculum vitae, one print of prior scientific publications, and the names and contact information of 3-5 references through the website. References will only be sought for finalists.

8646| Hospital of the University of Munich| Postdoc Position| The Hospital of the University of Munich, Germany, is one of the largest and most competitive university hospitals in Germany and Europe. 48 specialized hospitals, departments and institutions harbouring excellent research and education provide patient care at the highest medical level with approximately 10.000 employees.The Institute for Cardiovascular Prevention offers one Postdoc PositionArea of responsibilityLocal immunomodulation of atherosclerosis by CD8+ T-cell based nanomedicines.A Postdoc position is available to study native and liposome conjugated CD8+ T-cells and their interactions with foam cells and other atherosclerotic structures in both human and murine experimental models of atherosclerosis. The latter will be conducted by application of state-of-the-art imaging technology such as optoacoustic mesoscopy, optical nanoscopy, and multiphoton microscopy for studying novel experimental models.The project is part of a european research network (ERA-CVD) and combined with work programs of the consortium partners in Leiden (NL) and Ghent (BE) may ultimately lead to new protective pathways and therapeutic intervention strategies for treatment of atherosclerosis.Our requirementsEligible candidates should be a highly motivated team player. A strong affinity with advanced imaging technology is a prerequisite as well as experience with immunological and molecular biological techniques. Solid English skills, both written and spoken are a requirement, German language skills would be advantageous. The successful candidate should be independent and hold an above-average PhD degree in biology, biomedical sciences, or related fields. The Postdoc will be part of the institute for cardiovascular prevention (IPEK) at the LMU in Munich, Germany (www.klinikum.uni-muenchen.de/Institut-fuer-Prophylaxe-und-Epidemiologie-der-Kreislaufkrankheiten/de/0600-Institute/index.html).Our offerThe applicant will work in a group of experienced staff, PhD students, postdocs and technicians with excellent infrastructure and scientific skills. Moreover, the applicant will be able to further expand its network and become member of an international research project. Interested candidates should submit their electronic application (including motivation letter, CV, publication list and references) to:Remco Megens, email: [email protected] from severely handicapped persons with basically similar qualification will be given priority. Salary will be according to TV-L; The position is funded for up to 30 months.Please note that in case of transmitting your job application by e-mail your data will not be encrypted and might potentially be noticed or adulterated by unauthorized third parties. You are welcome to send us your documents by mail.Applicants (m/f/d) should submit their electronic application (including CV, motivation letter, publication list and references) to:Klinikum der Universität MünchenInstitut für Prophylaxe und Epidemiologie der KreislaufkrankheitenPettenkoferstr. 980336 Munich, Germany

8624| Syracuse University, Biology and Neuroscience| Postdoc studying neuronal specification in zebrafish in Lewis Lab| Applications are invited for a postdoctoral research fellowship to work in the Lewis Lab (http://lewislab.syr.edu/) examining how transcription factors specify the unique characteristics of spinal cord interneurons. The ideal candidate will be an experienced Developmental Biologist or Biochemist, preferably with experience of working with zebrafish. Experience in any of the following techniques would be an advantage: zebrafish embryology, in situ hybridization, immunohistochemistry, Biochemistry, live cell imaging using multiphoton/confocal microscopy, molecular biology, Co-IPs, constructing and analysing transgenic lines, FAC sorting and microarray analysis and/or bioinformatic analyses of RNA-Seq or Chip-Seq data.All candidates should have, or be about to obtain, a PhD in a relevant field.Applicants should fill in the job application at http://www.sujobopps.com/postings/81071job id 074691 and include a cover letter stating why they are interested in the position, a full CV with bibliography and the names, addresses and email addresses of at least three referees.Informal enquiries can be addressed to [email protected] may be read as they are received. Closing date: 30th August 2019.Only short-listed applicants will be contacted. The SU Biology department (biology.syr.edu) is a vibrant department with strengths in Developmental Biology, Genetics, Epigenetics, Neuroscience, Ecology and Evolution. Additional Neuroscience faculty are also located in other SU dpts (neuroscience.syr.edu/Faculty.html).Syracuse is an inexpensive and very pleasant and vibrant city to live in. It offers the amenities of a city without lots of the hastles. It has its own airport (15 minute drive from downtown) and is close to Toronto, New York City, Philadelphia, Montreal as well as the natural beauty of Upstate New York (Niagara Falls, The Finger Lakes, Adirondack lakes and mountains etc).Syracuse University also shares a campus with SUNY Upstate Medical University that has active research programs in Cell Biology, Developmental Biology and Neuroscience and the Lewis Lab regularly participates in seminar series and other programs with SUNY UMU researchers. http://www.upstate.edu/research/research-departments.php