7909| Czech Technical University in Prague| Postdoc openings in molecular simulations for lubrication| Applications are invited for two postdoctoral research fellows in the Advanced Materials Group (Department of Control Engineering, Faculty of Electrical Engineering, Czech Technical University in Prague) to work on the application of computational methods to the study of sliding contact properties of various materials.SHORT DESCRIPTION OF THE PROJECT: The project core objective is the reduction of friction by simulated-aided design of nanostructured materials. We will explore the interaction of surfaces with additives, contaminants, and pioneering novel tribological systems with water as a lubricant. The project is carried out in close collaboration with a world-leading industrial partner and combines different theoretical approaches in order to allow a rational design of surfaces and lubricants for automotive applications. Experimental validations of the in-silico predictions are also planned. The project will as well link activities at the Czech Technical University in Prague with the University of Southampton, UK.OBJECTIVES:The final goal is to study the frictional behaviour of complex surfaces (e.g., metal, oxides, ceramics, etc.) and their interaction with selected molecules (i.e., water, oils, oil additives etc.) by means of classical molecular dynamics simulations. In particular, one position will deal with the study of the interaction of selected oil molecules with specific oxide surfaces, whilst the other position is more oriented toward the understanding of molecular mechanisms underlying the interaction of carbon-based materials with selected tribological additives. Both crystalline and defective surfaces will be object of study.JOB REQUIREMENTS: Successful candidates must have a PhD in Physics, Chemistry, Materials Science or closely related disciplines. Experience with classical molecular dynamics simulations (using LAMMPS package preferably) is mandatory. Previous experience on the development of classical force fields and/or with the QM/MM method represents a plus. Researchers are expected to perform calculations on Linux-based HPC centers. Good knowledge of English, both written and oral, is compulsory.ABOUT THE GROUP: Advanced Materials Group is formed of experimentalists and computationalists working on coatings and low-dimensional systems for various applications. The group is well-established and consists of dynamic and motivated researchers leading international collaborations on broad interdisciplinary topics. In case of exceptional achievements, postdocs can be promoted to assistant professor (tenure track).CONTRACT DETAILS: The salary is competitive (approx. 25,000 EUR/year plus employer bonus). The positions are initially for 2 years and can be prolonged upon mutual agreement. Project duration is 5 years.HOW TO APPLY: The call is open immediately and the position will be filled as soon as a proper candidate is found – the starting date is expected to be no later than Q4/2018. Applications must include a brief description of research interests and relevant experience, the CV with publications, and at least two letters of recommendation of academic referees. Inquiries and applications shall be sent to: [email protected]

7903| Science and Technology Facilities Council| EO instrument Scientist| EO instrument Scientist - IRC245255UKRI - STFCRutherford Appleton Laboratory, Didcot£30,057 - £37,947 (depending on skills and experience)Full timeOpen endedAbout UsThe Science & Technology Facilities Council is a partner organisation within UK Research and Innovation (UKRI). UKRI is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation and a vision to ensure the UK maintains its world-leading position in research and innovation. STFC is a world-leading multi-disciplinary science organisation and our goal is to deliver economic, societal, scientific and international benefits to the UK and its people – and more broadly to the world.About the roleThe Earth Observation and Atmospheric Sciences Division within RAL Space are seeking to recruit an experimental physicist or engineer to work on the development of instrumentation for satellite and terrestrial remote sensing applications.You will work within the Radiometry Group, which has interests in all aspects of the collection and processing of satellite and field instrument data, particularly in the visible to infrared wavelength range, including instrument and subsystem design, calibration and data validation. The group is looking for a self-motivated candidate to work on significant projects and tasks, often involving satellite instrumentation. You should be able to analyse instrument data and write software and experimental procedures. We expect that you will develop skills in the design of instruments and calibration systems for optical measurements, generate documentation, manage work and interact with academic and industrial partners. While the group has important core activities, we would encourage the development of individual projects and research interests related to radiometry, climate, instrumentation and novel remote sensing techniques for the benefit of the UK space community.About youIt is essential that you have a first degree and doctorate or equivalent experience in applied physics, engineering or a related subject. You will have experience in experimental fields such as optical imaging systems, spectroscopy, thermometry and calibration as well as computer programming ability in a high-level language to process and interpret instrument data.You should be a team-player, self-motivated with an ability to multitask and prioritise work and have good spoken and written communication skills, particularly the ability to present clearly the analysis of complex problems. Experience of instrument calibration and an understanding of the treatment of measurement uncertainties is desirable for this role. What we offerAn exceptional index linked pension scheme, 30 days leave allowance and flexible working are offered.Full details of offered benefits can be found on STFC’s careers pages.How to ApplyApplicants are required to include a cover letter outlining their suitability for this role. Applications are handled by UK SBS; to apply please click the apply button. Applicants who are unable to apply online should contact us by telephone.The closing date for applications is 3rd July 2018.

7914| Institute of Public Health| Public Health Interventions Officer - Loneliness| The Institute of Public Health in Ireland (IPH) promotes cooperation for public health on the island of Ireland. The Bamford Centre for Mental Health and Wellbeing at Ulster University and the Institute of Public Health in Ireland are working together to identify the most effective interventions to address loneliness among older people. IPH invites applications for this fixed-term post of Public Health Interventions Officer – Loneliness.This post will be based between both organisations and aims to help inform the identification and design of effective Public Health interventions to address loneliness and to effectively measure the outcomes of these interventions.Job PurposeThe Bamford Centre for Mental Health and Wellbeing at Ulster University and the Institute of Public Health in Ireland are working together to identify the most effective interventions to address loneliness among older people. This post will be based between both organisations and aims to help inform the identification and design of effective public health interventions to address loneliness and to effectively measure the outcomes of these interventionsDuties To undertake a systematic review of the literature on the area of loneliness interventions. To explore methodologies for understanding loneliness across the lifecycle and within different populations. To assess both health professionals and wider societal understanding of loneliness using qualitative and quantitative methodologies. To appraise the level of stigma that is associated with loneliness across the lifecycle and within different populations. To develop an evaluation model to assess policy and services in the area of loneliness across the lifecycle. To explore and provide analysis and commentary on data sets that are relevant to understanding loneliness across the lifecycle including NICOLA, TILDA, Growing up in Ireland, Bio Bank. To explore the risk factors for loneliness especially the linkages between loneliness and depression, association and disassociation. To develop and facilitate collaborative partnerships in the area of loneliness across Ireland, the UK, Europe and internationally. To prepare material for publication in international academic journals and presentations at international conferences. To prepare funding proposals / applications to major external bodies. Coordinate and plan meetings and seminars. To undertake other duties as may be assigned from time to time by your line manager.When completing the application form please indicate how you meet all of the essential criteria and any of the desirable criteria.You can find the application form here: https://www.publichealth.ie/sites/default/files/2018-06/IPH%20Public%20Health%20Interventions%20Officer%20Loneliness%20Application%20form.docPlease return the completed application form via email to [email protected] before the deadline of noon on Friday 22nd June. Please note that C.Vs are not accepted.It is the responsibility of the applicant to ensure that their application form is received by IPH before the above deadline; you may wish to request a read receipt.IPH is an equal Opportunities Employer

7926| Institute of Public Health| Evaluations and Interventions Officer – Ageing and public health| Reporting to: Director of Ageing DivisionSalary: £25,167 - £34,218€38,133 - €51,847Duration: 24 monthsLocation: Belfast or Dublin, but the successful candidate will be expected to travel between both our offices and throughout Ireland (North and South) in the delivery of this role.Summary of main duties:Working at a strategic level this post will work in the area of evaluations and interventions as well as evidence, data and research syntheses relevant to ageing and public health.1. To undertake evidence syntheses to inform policy and practice relating to ageing and public health.2. To identify evaluation models most relevant to assessing impact of programmes, policy and services relating to public health and ageing.3. To advise and assist with evaluations of selected Government policy and programmes.4. Using evaluative methodologies to assess the impact of selected Government and non-Government interventions relevant to public health and ageing.5. To collate and analysis secondary data (qualitative and quantitative) relating to ageing and public health.6. To produce briefings on selected public health and ageing issues.7. To assist with the convening of events and meetings.8. To make presentations to key audiences in the area of public health and ageing.9. To work collaboratively to help improve population health in Ireland North and South.10. To represent IPH on relevant outside bodies and events.11. To contribute to the promotion of IPH.12. To undertake other duties as may be assigned from time to time by your line manager.The above is not an exhaustive list of duties and you will be expected to perform different tasks as necessitated within the organisation and the overall business plan.2PERSON SPECIFICATIONEssential CriteriaQualifications Degree (Hons)Desirable Criteria Post Graduate qualification in relevant disciplineExperience At least 2 years recent research experience relevant to this project Experience of synthesising different sources of data and research to inform policy and practice Experience of producing and preparing reports and/or briefings from research and data Experience of programme and /or policy evaluationSkills & Knowledge Understanding of evaluation models Strong research and analytical skills - qualitative and quantitative Evidence of excellent communication skills – orally and in writing Excellent IT skills e.g. Microsoft Office suite Ability to work independently and within a team Knowledge of policy context relating to ageing and public health in Ireland North and South Knowledge of key data sets relating to ageing and older people in Ireland, North and SouthPersonal High degree of organisational ability, self-motivation, ability to meet tight deadlines and work flexibly, independently and on own initiative

7918| University of Montreal| Postdoctoral fellow in Human Genetics| The lab of Dr. Philippe Campeau focuses on studying new skeletal dysplasias, new forms of epilepsy and chromatin remodeling disorders (www.pcampeaulab.org). We identify new disease-causing genes, understanding the pathological basis of disease, and try to improve the management of children affected by these conditions.The tasks of the trainees will be to analyze exome and genome data to identify causative mutations. Then, the mutations will be introduced in expression vectors by standard molecular biology approaches, or in cell lines (such as induced pluripotent cell lines) by the CRISPR/Cas9 approach. In vitro, the effect of the mutations on the gene's pathway will be assessed by a combination of analysis of RNA, protein and cell studies. These techniques include but are not limited to RNA-seq, ChIP-seq, ATAC-seq, and flow cytometry. In addition, the mutations may be introduced in muce also by the CRISPR/Cas9 approach, to eventually phenotype these mice to better understand the effect of the mutations.Applicants should have extensive molecular biology experience in research labs, and provide simply a CV and university transcripts to Dr. Campeau at [email protected] In compliance with Canadian immigration requirements, priority shall be given to Canadian citizens and permanent residents. The University of Montreal and the CHU Sainte-Justine Research Center (https://research.chusj.org) subscribe to equal opportunity hiring and invites women, members of visible minorities, members of ethnic minorities, individuals with handicaps and native people to apply.

7932| University of Manchester, The Cancer Research UK Manchester Institute| Postdoctoral Scientist – Stem Cell Biology| About the role:A three year position is available in the laboratory of Georges Lacaud to investigate the role of genes specifically expressed in leukaemic cells and to further validate and progress them as potential therapeutic targets. Leukaemia is the 8th most common cause of cancer death in Europe. The main goal of the Stem Cell Biology group is to identify new therapies for Acute Myeloid Leukaemia (AML). Treatments of AML have not dramatically changed, or improved, in the last 30 years and there is therefore a pressing need for the development of more specific and efficient therapies. In this context, the group is particularly interested in investigating the role and requirements of transcription factors recurrently rearranged or mutated in human leukaemias such as the master regulator of blood development AML1/RUNX1 or the transcriptional co-activator MOZ.About you:You should have a PhD in molecular or cellular biology (or a relevant field). Relevant experience in haematopoiesis or leukaemia working with cellular or in vivo models is essential. Bioinformatic skills are desirable. Key qualities should include independent thinking, ability to work in a team and good communication skills, all of which are needed to efficiently work in a multidisciplinary team.Why choose Cancer Research UK Manchester Institute?The Cancer Research UK Manchester Institute (www.cruk.manchester.ac.uk), an Institute of The University of Manchester (www.manchester.ac.uk), is a world-leading centre for excellence in cancer research. The Institute is core funded by Cancer Research UK (www.cancerresearchuk.org), the largest independent cancer research organisation in the world. We are currently situated at the internationally renowned life sciences campus at Alderley Park in Cheshire England, 15 miles from Manchester, a vibrant and dynamic city surrounded by beautiful countryside.We are partnered with The Christie NHS Foundation Trust (adjacent to the CRUK Manchester Institute, Paterson Building) in South Manchester (www.christie.nhs.uk), one of the largest cancer treatment centres in Europe. These factors combine to provide an exceptional environment in which to pursue basic, translational and clinical research programmes. How to apply:To apply for this position please visit our website: http://www.cruk.manchester.ac.uk/Opportunities/Opportunities-Home Informal enquiries should be directed to Georges Lacaud via email: [email protected] Closing date: 16 July 2018.

7929| Edinburgh Napier University, School of Applied Sciences| Postdoctoral Research Fellow - Osteoarthritis| We are currently looking to appoint a postdoc to work on a project funded by the Medical Research Council on osteoarthritis, in the lab of Dr Katherine Staines. The project aims to investigate whether altered growth dynamics contribute to osteoarthritis vulnerability, and whether their manipulation offers the potential for new therapeutic strategies for osteoarthritis. The applicant will join a dynamic research group that has a broad interest in the mechanisms underpinning osteoarthritis. The main responsibilities will be to design and perform the experimental work as outlined in the project award, utilising a variety of in vitro, in vivo and molecular techniques. The applicant will be expected to contribute to the effective communication and publication of the findings in the scientific literature and at national and international scientific conferences. They will also be involved in the training of postgraduate research students.The successful candidate will have a PhD and strong grounding in bone/cartilage biology. They should have existing research expertise, preferably within in vivo studies, molecular and cellular biology techniques, cell culture and imaging. They will also have experience in statistical analysis of data and the ability to communicate complex information clearly both orally and in writing, as evidenced by a track record of research outputs.

7934| University of Sussex, School of Engineering and Informatics| Post-Doctoral Research Fellow in Neuromorphic Computing| Hours: full timeContract: fixed term until 31 March 2020 Reference: 3436 Salary: starting at £32,548 and rising to £38,833 per annumPlaced on: 19 June 2018Closing date: 24 July 2018. Applications must be received by midnight of the closing date. Expected Interview date: 20 August 2018Expected start date: 01 October 2018We are seeking to employ a post-doctoral research fellow within the Sub-Project 9 of the Human Brain Project (HBP, https://www.humanbrainproject.eu/en/) to work on applications of neuromorphic computing. The Human Brain Project is a €1 Billion EU Flagship project with the aim of creating the IT tools for deciphering the workings of the Human Brain.Under the supervision of Prof Thomas Nowotny you will work with the neuromorphic computing platforms of the HBP, in particular the BrainScaleS system developed at the University of Heidelberg. You will develop applications for neuromorphic computing and evaluate them in simulation and on the actual hardware. Applications can range from machine learning, for example in the area of “learning to learn”, to computational Neuroscience.Competitive candidates for this position will have a keen interest in neuromorphic computing, excellent programming skills and experience in one or more of the areas of (1) machine learning(2) computational Neuroscience, or(3) neuromorphic computing.When applying, please fill in the application form and attach a full CV. Use the space for additional information in support of your application to address in detail why you are the best candidate for the position, making reference to the role specific criteria as outlined in the Job Description.For informal enquiries, please contact Prof Thomas Nowotny ([email protected]).For full details and how to apply see our vacancies page - http://www.sussex.ac.uk/about/jobsThe University of Sussex values the diversity of its staff and students and we welcome applicants from all backgrounds.

7927| University of Kent, School of Biosciences| A Generalised Approach to Derive Functionally Active Peptide Inhibitors of Transcription Factor Activity| Dr Neil Kad’s lab at the University of Kent is looking for a bright and enthusiastic individual who is interested in using state-of-the-art single molecule techniques to image transcription factor interactions with DNA tightropes (see Kad et al., 2010). The project is wide-ranging from protein biochemistry to single molecule data collection and analysis. This project will be undertaken in collaboration with partners and will require travel in the UK and possibly beyond.This interdisciplinary project is aimed at understanding how inhibitors of transcription factor proto-oncogenes work. By directly imaging of RNA polymerase moving along DNA, we will learn how inhibitors exert their action and using this information we can work with the Mason group at the University of Bath to generate better inhibitors. We have fully developed the technology to visualise six fluorophores in wide-field microscopy simultaneously, enabling us to image multiple components acting together. In addition, the inhibitor selection assay is fully developed at the University of Bath. This is a hugely valuable project, for which training and support will be given throughout, including regular meetings between team members and a 6-week exchange programme with the University of Bath to gain new skills and enhance progress The Kad lab is very well-equipped with microscopes dedicated to single molecule fluorescence imaging, dark-field and laser tweezers. In addition, the School of Biosciences at Kent houses numerous shared facilities from NMR and Mass Spectrometry to cell biology and super-resolution imaging. This 3-yr BBSRC funded Postdoctoral position is available from 1st August and applicants must have or be about to receive a PhD in a relevant science subject. Candidates should also have experience in protein biochemistry/biophysics and preferably single molecule/microscopy methods. For more information or informal enquiries please contact Dr. Neil Kad: [email protected] +44 1227 816151. Deadline for applications: 5 July 2018

7930| Max Delbrueck Centre for Molecular Medicine, Berlin Institute for Molecular Systems Biology| postdoc position in ‘Roles of RNA-binding proteins in subcellular RNA localization and translation in neurons’| The subcellular localization and translation of mRNAs are fundamental biological processes. They underlie establishment of body axis, cell growth, cell migration, and synaptic plasticity, which serves as a foundations of learning and memory. Many neurological disorders are associated with a failure to localize and translate mRNAs at specific subcellular sites. Our prior work has identified RNAs and proteins asymmetrically localized and translated in neurons, including neurite-enriched RBPs and miRNAs with potential regulatory roles in these processes (Zappulo et al., 2017). The aim of the project will be to dissect the mechanisms underlying asymmetric RNA localization and translation in neurons, focusing on the roles of identified neurite-enriched RBPs and miRNAs. The project will involve a combination of biochemical (RNA-seq, Ribosome profiling, polysome profiling, PAR-CLIP, RNA-IP, CRISPR/Cas-mediated knockouts and tagging, reporter assays), computational and imaging approaches in cultured cells (mESC and hiPSC differentiation systems) and primary neurons. Candidates will contribute to data integration and development of new computational tools to model the data to explain and predict localization and translation patterns of RNAs in different types of neuronal cells.Ideal candidate should have PhD degree in biology, biochemistry, molecular or computational biology and interest in RNA biology and mechanisms of gene regulation. Wet-lab biologists should have experience in molecular biology techniques and cell culture, expertise in RNA biology and NGS are an advantage. Computational candidates should have excellent programming skills for data analysis preferably in R and in one of the scripting languages such as Perl/Python. Statistics and machine learning skills is also desirable. To apply, please send your motivation letter and CV with contact details of two referees to marina.chekulaeva(at)mdc-berlin.deThe Max Delbrück Center for Molecular Medicine (MDC) is one of the leading biomedical institutes dedicated to interdisciplinary research. The most recent expansion of the MDC is the Berlin Institute for Medical Systems Biology (BIMSB). BIMSB is a multidisciplinary environment with half computational and half wet biology labs, running an extensive scientific program in systems biology, integrating high-throughput technologies with bioinformatics, biochemistry, molecular and developmental biology. For more information on the institute and the lab: www.chekulaevalab.org; www.mdc-berlin.de/bimsb

7933| Max Planck Institute for Molecular Biomedicine, Regulatory Genomics| Genomic Analyses of Chromatin Conformation Dynamics in Development and Evolution| Our laboratory seeks to appoint a highly motivated scientist to work on dissecting the molecular mechanisms that regulate chromatin conformation in eukaryotes, which is a strong focus of the group (Hug et al., Cell 2017). In particular, the successful candidate will generate and analyse Hi-C datasets to investigate how chromatin conformation is established and its impact in regulating the correct deployment of developmental gene expression programmes or in disease. The position will also involve integrative analysis of Hi-C and other relevant genomic datasets (RNA-seq, ChIP-seq, ATAC-seq, CUT&RUN, etc) as well as generating additional datasets where necessary. RequirementsWe are looking for an enthusiastic and talented postdoctoral fellow with a PhD in molecular biology, genetics, epigenomics, computational biology, bioinformatics, biostatistics, or a related field, and with a strong drive to excel in a highly international and collaborative environment. Previous experience in genomic data analysis (e.g., Hi-C, RNA-seq or ChIP-seq) is highly desirable but not required. A successful candidate without previous programming or genomic data analysis experience will be expected and supported to develop these skills as part of the position. Prior programming experience, proficiency in genomics data analysis, and/or a demonstrable interest in developing these skills should be detailed in the cover letter. Terms of employmentThe position is offered initially as a fixed-term appointment for one year with the possibility of further extension following a successful evaluation. The position is available immediately.How to applyApplications should be sent as a single pdf file by email to [email protected] Please make sure to include the position code 15-2018 in the subject line. Applications received before 30 June 2018 will be considered first. These should include: (i) a cover letter explaining your motivation to join the laboratory; (ii) a full CV; and (iii) the contact details of two academic referees. Incomplete applications will not be considered. For informal queries and further information please contact Juanma Vaquerizas ([email protected]) or visit www.vaquerizaslab.org.About MPI MuensterThe Max Planck Institute for Molecular Biomedicine offers a highly international and stimulating research environment with state-of-the-art equipment and core facilities for genomics, proteomics and cell biology. The Institute is located in Muenster (http://www.muenster.de/en/), one of the European Green Capitals and former UN’s ‘The World’s Most Liveable City’ awardee. Extra administrative help will be available for foreign scientists. English is the working language in the Institute.The Max Planck Society seeks to increase the number of women in those areas where they are underrepresented and therefore explicitly encourages women to apply. The Max-Planck society is committed to increasing the number of individuals with disabilities in its workforce and therefore encourages applications from such qualified individuals.More details about the Vaquerizas laboratory and the Institute can be found here:http://www.vaquerizaslab.orghttp://www.mpi-muenster.mpg.de/en

7928| Institute of Public Health| Knowledge Translation Officer - Ageing and Public Health| Reporting to: Director of Ageing DivisionSalary: £33,114 - £42,219/ €50, 175 - €63,974Location: Dublin or Belfast, but the successful candidate will be expected to travel between both our offices and throughout Ireland (North and South) in the delivery of this role.Summary of main duties:Working at a strategic level this is focused on translating research, data, policy and practice relevant to public health and ageing. The translation function means drawing on a range of data, research reports and analysis and turning these into formats that are usable by policy makers, professionals and practitioners. It also involves scanning trends, policies and practice to identify key issues for research on ageing and inequalities.Duties:1. To translate data, research, policy and practice relevant to public health and ageing into multiple formats that will be accessible, usable and actable by decision-makers and the policy community.2. To advise on development, implementation and evaluate the impact of Government programmes and policy.3. To undertake evidence syntheses to inform decision-making processes (including guideline development) relating to ageing and public health.4. To undertake primary and secondary policy and practice focused research (qualitative and quantitative) relating to ageing and public health.5. To undertake periodic analysis of policies, literature and frameworks (local, national, EU and international) relevant to demographic change, ageing and public health.6. To collate, analyse and interpret key data sets relevant to ageing and public health eg TILDA, NICOLA, CSO, NISRA.27. To service and develop IPH North/South networks focused on research and policy to assist implementation.8. To produce user-accessible articles, reports and briefings on key public health and ageing issues.9. To convene events and build strong working relationships with key stakeholders: policy-makers, researchers and activists to advance ageing and public health agenda.10. To make presentations to key audiences in the area of public health and ageing.11. To work collaboratively to help improve population health in Ireland North and South.12. To raise awareness and understanding of the connection between poverty and determinants of health inequalities as well as demographic ageing and public health.13. To represent IPH on relevant groups, bodies and events and contribute to the promotion of the organisation across stakeholders.14. To undertake other duties as may be assigned from time to time by your line manager.The above is not an exhaustive list of duties and you will be expected to perform different tasks as necessitated within the organisation and the overall business plan.3PERSONNEL SPECIFICATIONFor those applicants that meet all the essential criteria please note there will be a practical assessment to progress to interview.Essential CriteriaQualifications Degree (Hons)Desirable Criteria Post Graduate qualification in relevant disciplineExperience Have recent (at least 5 years) demonstrable experience within a policy or research context Have substantial demonstrable experience of translating and synthesising data, research and policy Experience of producing and preparing policy focused reports and/or briefings from research and data Experience of programme and or policy reviews Experience of convening events and meetings with a range of stakeholders Experience of working in a relevant ageing or public health fieldSkills & Knowledge A sound understanding of the strategic context of policy relating to older people i.e. International, EU, National Government policy and practice Excellent research and analytical skills - qualitative and quantitative Evidence of excellent communication skills – orally and in writing i.e. ability to adapt style and message to different audiences High level of IT literacy in use of MS Office Ability to work independently and within a team Strong knowledge of key issues relating to ageing and public health in Ireland North and South Sound knowledge of key data sets relating to ageing and older people in Ireland, North and SouthPersonal High degree of organisational ability, self motivation, personal initiative, ability to meet tight deadlines and work flexibly

7931| University of Kent, School of Biosciences| Generation and characterization of a humanized APOBEC3 mouse: a crucial tool for target validation and preclinical development of APOBEC inhibitors as anti-cancer drugs| We are seeking an experienced and motivated individual to undertake post-doctoral research funded by Cancer Research UK. The project is three years in duration with funding renewed annually subject to satisfactory progress. The lab focusses on the molecular mechanisms underlying cancer development, The project will focus on development and characterisation of a novel mouse model for studying a family of deoxycytidine deaminase enzymes (APOBEC3) which have been implicated in generating somatic mutations that drive cancer development and resistance to therapy. This model will serve as a unique tool for fundamental research into APOBEC3 biology and as a preclinical model for the development of APOBEC3 inhibitors as anti-cancer drugs. You will be working as part of a dynamic group within the School of Biosciences at the University of Kent and in close collaboration with our co-investigators at Imperial College London, the University of Cambridge and the Institute for Cancer Research. The School offers a supportive and nurturing environment for post-doctoral research.The applicant will need a PhD in an appropriate field, and in particular, will need experience working with laboratory mice. They will have the ability to work independently, efficiently, creatively and collegially, and to co-supervise graduate students. They will possess strong written and oral communication skills and be highly self-motivated.

7916| THE UNIVERSITY OF LIVERPOOL/INSTITUTE OF TRANSLATIONAL MEDICINE, DEPARTMENT OF CELLUAR AND MOLECULAR PHYSIOLOGY| POSTDOCTORAL RESEARCH ASSOCIATE GRADE 7| We are seeking a highly motivated individual for a BBSRC funded project in the laboratory of Dr. Natalia Sanchez-Soriano (https://sanchezlab.wordpress.com), to study the cell biology of neuronal ageing and the underlying mechanisms. Using a powerful new in vivo model of neuronal ageing within the Drosophila brain, you will characterise the harmful changes that neurons undergo at the subcellular level during ageing, and unravel the cascade of events that cause them, with a focus on intracellular degradation systems and the upstream regulatory pathways. You should have a Ph.D. in the life sciences or another relevant subject and evidence of prior research productivity. Ideally applicants should be trained in neuro- and/or in vivo cell biology, and imaging, and have experience with Drosophila. The post is available from 1st of September 2018 until 31st of August 2021.Job Ref: 009401

7905| Queen Mary University of London, School of Biological & Chemcial Sciences| Postdoctoral Research Assistant| School of Biological & Chemical SciencesPostdoctoral Research AssistantQMUL15147A Postdoctoral Research Assistant position is available at Queen Mary University of London (QMUL) in the group of Dr Christian Nielsen (https://nielsen-lab.com/) to work on an EPSRC-funded project entitled “Additive-Stabilized Polymer Electronics Manufacturing” in collaboration with Prof Henning Sirringhaus, University of Cambridge.This particular research position will focus on the synthesis and characterization of novel conjugated organic materials for use in organic electronics, specifically focusing on enhancing the performance and stability of organic electronic devices such as the organic field-effect transistor (OFET) and the organic light-emitting diode (OLED). The successful applicant will work within the School of Biological and Chemical Sciences at QMUL (http://www.sbcs.qmul.ac.uk/) under the direct supervision of Dr Christian Nielsen but will also collaborate closely with the project partners in Cambridge. The ideal candidate for this position should have a PhD in organic chemistry or a closely related field and be able to work effectively, independently and sociably within a team and have an interest/knowledge in materials science. Experience in conjugated small molecule and polymer synthesis and the ability to interact within an interdisciplinary research area are vital. This is a full-time, fixed term post available for 12 months in the first instance, with a start date of mid July 2018 or as soon as possible thereafter. The salary is in the range of £30,445 - £34,764 per annum based on qualifications, skills and experience and is inclusive of London allowance. Benefits include 30 days annual leave, pension scheme and season ticket loan.Candidates must be able to demonstrate their eligibility to work in the UK in accordance with the Immigration, Asylum and Nationality Act 2006. Where required this may include entry clearance or continued leave to remain under the Points Based Immigration Scheme.Informal enquiries may be made to Dr Christian Nielsen via e-mail: [email protected] enquiries should be directed to [email protected] apply, please click link below. https://webapps2.is.qmul.ac.uk/jobs/job.action?jobID=3385The closing date for applications is 4 July 2018. Interviews will be held shortly thereafter. Valuing Diversity & Committed to Equality

7910| Czech Technical University in Prague| Postdoctoral position in the theoretical computation of structural and electronic properties of photovoltaic materials| The Center of Advanced Photovoltaics of the Faculty of Electrical Engineering, Czech Technical University in Prague, invites applications for a postdoctoral position in theoretical computation of structural and electronic properties of photovoltaic materials.The work will involve theoretical modelling of electronic states and the interaction between silicon and a molecular dipole on the surface. The focus will be on a quantitative description of the energy transfer from an excited molecular state to excite electron-hole pairs in the semiconductor, similar to the resonance (Förster) energy transfer between molecules. Key quantity of interest is the static (ω = 0) dielectric constant / function at large values of the wave vector k. The calculation should take into account in detail the dielectric screening of the interaction as well the apparent bandgap (direct or indirect) which characterises the excitation of the electron-hole pairs in the semiconductor.ABOUT THE WORKPLACE:Center of Advanced Photovoltaics (CAP, cap.fel.cvut.cz) at the Faculty of Electrical Engineering, Czech Technical University in Prague has been established to face challenges in the area of photovoltaics from atomistic models and novel solar cell designs to urbanistic and architectural concepts. The Center of Advanced Photovoltaics, in a close partnership with University of Southampton (U.K.), lays the foundation for prime research in theoretical and applied photovoltaics taking advantage of unique multidisciplinary environment. The Center is lead by experienced and recognized senior researchers, including prof. Tomas Markvart as the Center head, and supported by a dedicated administration team. The Center is an inherent part of the Faculty of Electrical Engineering, which is a workplace including 3500 students, 380 academic staff, and annual budget exceeding 840 million CZK. Study programs are taught in Czech as well as in English with a strong emphasis on international exchange and collaboration.JOB REQUIREMENTS:Successful candidates must hold a Ph.D. degree (or equivalent) in Physics, Chemistry, Materials Science or closely related disciplines. Previous experience with DFT calculations, Green’s function-based techniques, and QM/MM or research in photovoltaics is highly welcome. Prior publications as the first author in recognized scientific journals, as well as good knowledge of English (both written and oral) are compulsory. Teamwork with Ph.D. and Master students is expected. Building up own research team is encouraged. CONTRACT DETAILS:The salary will be competitive (approx. 25,000 EUR/year plus employer bonus). The positions are initially for 2 years and can be prolonged upon mutual agreement. Project duration is 5 years.HOW TO APPLY:The call is open immediately and the position will be filled as soon as a proper candidate is found – the starting date is expected to be no later than Q4/2018. Applications must include a brief description of research interests and relevant experience, the CV with publications, and at least two letters of recommendation of academic referees. Inquiries and applications shall be sent to: [email protected]

7912| University College London| Research Associate in Computational Simulation of Cerebral Blood Flow| The appointment will be on UCL Grade 7. The salary range will be £34,635 to £41,864 per annum, inclusive of London Allowance.Applications are invited for a Research Associate to work with Professor Peter Coveney in the Department of Chemistry at University College London. The successful candidate will join a very active inter-disciplinary group in the Centre for Computational Science, and will work on providing guiding theoretical principles and computational methods for the design of novel materials based on their atomic composition and structure. The post-holder will work primarily on scientific applications of HemeLB, a flexible lattice-Boltzmann code for the simulation of blood flow in support of medical and clinical decision making and for physiological research. The postholder will be expected to engage closely in the development of software within the project, including contributions to the verification, validation and uncertainty quantification toolkit which will be a central output of VECMA.The post is funded by the European Commission and is available from 15 June 2018 or soon thereafter, for a period of 24 months initially. The successful candidate will have a PhD degree (or about to be awarded a PhD) in an area of the mathematical, physical, engineering and computer sciences or related areas, with extensive experience of modelling and simulation, particularly involving high performance computing, preferably with the lattice-Boltzmann method. An excellent and consistent publication track record is also essential. Please note, appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at Research Assistant Grade 6B (salary £30,316 to £31,967 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis.For further details about the vacancy and how to apply online please go to https://www.ucl.ac.uk/human-resources/working-ucl/jobs-ucl and search on Reference Number 1727273.Informal enquiries should be addressed to Prof Peter Coveney ( [email protected] ). Any queries on the application process can be directed to Judith James – [email protected] .Closing Date: 1 July 2018Latest time for the submission of applications: 23:59.Interview Date: TBCWe particularly welcome applications from black and minority ethnic candidates as they are under-represented within UCL at this level. Our department holds an Athena SWAN Bronze award, in recognition of our commitment to advancing gender equality.To apply click here https://atsv7.wcn.co.uk/saf/login.cgi?SID=ZXh0ZXJuYWw9MjM5OTI3Jm93bmVydHlwZT1mYWlyJmpjb2RlPTE3MjcyNzMmb3duZXI9NTA0MTE3OA==

7892| D. E. Shaw Research| Postdoctoral Fellowships in Computational Chemistry and Physics at D. E. Shaw Research| D. E. Shaw Research is seeking postdoctoral fellows of exceptional ability to join our New York–based team. This is a unique opportunity to develop and work with transformative technology in a dynamic, interdisciplinary environment. Candidates should have expertise in computational, theoretical, or quantum chemistry, theoretical chemical physics, applied mathematics, or in a relevant area of computer science. Relevant areas of experience might include force field improvement through detailed comparisons of simulation data with NMR measurements or other experimental data, development and implementation of new methodology, such as integrators or efficient approximations of long-range forces, methods for enhanced sampling or free-energy calculations, or tools to efficiently analyze large simulation datasets. Specific knowledge of any of these areas is less critical, however, than outstanding intellectual ability, unusually strong research skills, and a history of innovation and accomplishment. We are committed to fostering a stimulating, rewarding, and flexible work environment, and we offer above-market compensation to candidates of truly exceptional ability.To submit an application, please use the link provided below: http://www.deshawresearch.com/recruit/jobs/Ads/FindAPostDoc/ChemPF-MD. E. Shaw Research is an independent research group that is pursuing an ambitious, long-term strategy aimed at fundamentally transforming the process of drug discovery. We have developed a special-purpose supercomputer capable of executing molecular dynamics (MD) simulations orders of magnitude faster than was previously possible. Our current projects include investigations of proteins and other biomedically relevant macromolecules as well as the development of computational chemistry methods to enable more accurate and effective MD simulations.D. E. Shaw Research is an equal opportunity employer, dedicated to the goal of building a diverse workforce. We welcome inquiries from all exceptionally well-qualified applicants, regardless of race, color, gender, age, religion, national origin, sexual orientation, gender identity, disability, pregnancy, marital status, military service eligibility, veteran status, or status in any other category protected by law.

7891| D .E. Shaw Research| Postdoctoral Fellowships in Computational Chemistry and Biology at D. E. Shaw Research| D. E. Shaw Research is seeking postdoctoral fellows of exceptional ability to join our New York–based team. This is a unique opportunity to develop and work with transformative technology in a dynamic, interdisciplinary environment. Candidates should have expertise in computational biophysics or chemistry, structural biology, drug discovery, or in a relevant area of computer science. Relevant areas of experience might include direct application of molecular dynamics or other computational methods to drug discovery, investigation of allosteric interactions or other functionally important conformational changes in biological molecules, structure prediction or design for proteins or RNA, study of protein–protein or protein–nucleic acid interactions, or study of fundamental biophysical problems, such as protein and RNA folding. Specific knowledge of any of these areas is less critical, however, than outstanding intellectual ability, unusually strong research skills, and a history of innovation and accomplishment. We are committed to fostering a stimulating, rewarding, and flexible work environment, and we offer above-market compensation to candidates of truly exceptional ability.To submit an application, please use the link provided below: http://www.deshawresearch.com/recruit/jobs/Ads/FindAPostDoc/ChemPF-AD. E. Shaw Research is an independent research group that is pursuing an ambitious, long-term strategy aimed at fundamentally transforming the process of drug discovery. We have developed a special-purpose supercomputer capable of executing molecular dynamics (MD) simulations orders of magnitude faster than was previously possible. Our current projects include investigations of proteins and other biomedically relevant macromolecules as well as the development of computational chemistry methods to enable more accurate and effective MD simulations.D. E. Shaw Research is an equal opportunity employer, dedicated to the goal of building a diverse workforce. We welcome inquiries from all exceptionally well-qualified applicants, regardless of race, color, gender, age, religion, national origin, sexual orientation, gender identity, disability, pregnancy, marital status, military service eligibility, veteran status, or status in any other category protected by law.

7900| Institute of Fundamental Sciences, College of Sciences| Postdoctoral Fellow in Computational Transcriptomics| We are looking for a computational biologist with the necessary academic training and competency to analyse a large transcriptome data set we have generated from endophyte infected grass tissue. The project is led by Professor Barry Scott and is collaborative with Professor Christopher Schardl at the University of Kentucky and Professor Murray Cox at Massey University. We are interested in identifying genes that are differentially expressed during the onset of stromata (sexual stage) development on the grass host. We have isolated RNA from different tissues of three different fungal-grass associations. We have gene models for the fungal components of all three associations but gene models for just one host. The post doc will be expected to develop their own hypotheses in analyzing this very large data set and work with a wider group working on the genomics, transcriptomics and functional analysis of fungal-grass associations. The analytical position requires solid quantitative and computational skills, with the ability to develop and apply new bioinformatics applications to the analyses. At a minimum, some confidence in bioinformatics and a programming language is required. Training in fungal biology or genomics can be provided as needed, and candidates from non-standard research backgrounds with a clear fit to the position are encouraged to apply.Funding is available for just one year from a research sub-contract with the Bioprotection Research Centre to Massey University. Salaries are competitive starting at $69,841 for Step 1 of the Postdoctoral scale. The position will be based at Massey University, in the city of Palmerston North. All enquiries should be directed to Professor Barry Scott via telephone +64 6 9517704, e-mail [email protected] submit an application, please provide the following:1. A brief statement of research interests and experience, focusing on short to medium term career goals and your fit for this position2. Curriculum vitae, including qualifications and scientific publications3. The names and contact details of three referees willing to provide a confidential letter of recommendation upon requestClosing date: 30 June 2018Reference number: A170-18CAFor further information and to apply online, visit: http://massey-careers.massey.ac.nz/

7899| ENABLE| European Academy for Biomedical Science announces The 2nd ENABLE symposium for PhDs and Post Docs| The Promise of future medicine: from research to therapyCopenhagen, 6-9 November 2018ENABLE is a European symposium organized by, and for, PhD students and Postdocs, that will take place with its second edition in Copenhagen from the 6th to the 9th of November 2018. This initiative seeks to promote excellence in the biomedical sciences in Europe by supporting young researchers, strengthening scientific careers, and bringing biomedicine closer to society. To achieve this, ENABLE is organized in three main pillars:Scientific symposium: Two full days on which young scientists from all over Europe will learn about different biomedical fields and cutting-edge techniques through talks, and informal chats with renowned scientists.Career day: A full day on which participants will be able to attend different workshops, chats with professionals, and learn about career opportunities at the “opportunity fair”, in which companies from the publishing world to the biotechnological and pharmaceutical sectors will be present.Outreach activities: To allow participants to explain biomedicine among citizens and bring science closer to society.The ENABLE conference is about opening academia from within to promote a new research culture through a real exchange between young scientists, renowned researchers, industry professionals and citizens. Moreover, unlike other conferences, PhD students and postdoctoral fellows are in charge of the event as a way of empowering them in choosing their future.This initiative has been cofunded by the European Commission led by four research institutes (IRB Barcelona, RIMLS, NNF CPR, SEMM, and a science communication agency (Scienseed).Registration is now open. Early bird discounts are available until July 31. A considerable number of travel grants are available for eligible participants who actively participate via poster presentation, short talk or micro talk. The deadline to apply for travel grants is June 15.For more information visit our website or follow us on Facebook and Twitter.Let’s spread the word to ENABLE the change!

7917| University College Dublin, UCD Sutherland School of Law| UCD Post- Doctoral Research Fellow Level 1 or Level 2, UCD Sutherland School of Law (Temporary)| Applications are invited for a temporary postdoctoral researcher, UCD Sutherland School of Law, to form part of a team funded by the European Research Council.This is an exciting opportunity to play an important role on a cutting-edge project investigating the way that laws influence our decisions to engage (or not to engage) in environmentally compliant behaviour in Europe. You will be the postdoctoral researcher on the project, and will form part of an interdisciplinary international team of six people, comprising Professor Kingston, 3 Ph.D. students, a research assistant and the postdoctoral researcher.The project, which has been running since 2015, is now entering the data analysis phase, and the successful candidate will have particular responsibility for helping to analyse the data collected, including by means of statistical regression analysis, and also data collected from surveys and interviews. The successful candidate will also help to design the final part of the project which employs behavioural economics techniques. The position may involve some travel from time to time within the EU, depending on the candidate’s interest, linguistic skills and availability.Salary: PD1: €36,854 - €42,603 per annum. PD2: €43,828 - €47,728 per annum.This position may be appointed at either UCD Post-Doctoral Research Fellow Level 1 or Level 2 depending on the relevant qualifications and experience of the successful candidate.Closing Date: 17.00hrs (Local Irish Time) on 3 July 2018.Applications must be submitted by the closing date and time specified. Any applications which are still in progress at the closing time of 17:00hrs (Local Irish Time) on the specified closing date will be cancelled automatically by the system. UCD are unable to accept late applications.UCD do not require assistance from Recruitment Agencies. Any CVs submitted by Recruitment Agencies will be returned.Prior to application, further information (including application procedure) should be obtained from the Work at UCD website: https://www.ucd.ie/workatucd/jobs/.

7921| University of Edinburgh, College of Science and Engineering| Postdoctoral Research Associate| Institute of Evolutionary BiologyPDRA position: Phylogenetic Epidemiology and Phylodynamics of HIV in AfricaThe Institute of Evolutionary Biology at the University of Edinburgh seeks to appoint a Postdoctoral Researcher to work with Andrew Rambaut’s group, using virus genomic data to understand the phylodynamics, epidemiology, and molecular evolution of HIV in long-term patient cohorts and the generalised epidemic in Sub-Saharan Africa.The successful applicant will be working closely with project collaborators at Oxford, Johns Hopkins, UCL and the Africa Health Research Institute (AHRI), as part of the PANGEA-HIV consortium studies. Funded by the Bill and Melinda Gates Foundation this project aims to improve our understanding of HIV epidemiology in order to design targeted HIV control strategies and to understand impact of HIV interventions. The consortium’s goal is to analyse HIV-1 phylogenetic data, to identify the individual and population drivers, hubs, sources, sinks and dynamics of epidemic spread, and to translate that to information that is directly actionable in HIV prevention. The applicant will undertake analyses of over 15,000 HIV genomes and associated epidemiological data, developing state-of-the-art statistical models and tools to advance this goal. Candidates will have a PhD in a relevant field (computational biology, computer science, mathematical biology or statistics), will have expertise in phylodynamics, molecular evolution or phylogenetic epidemiology of viruses, strong skills in computational biology, statistics or sequence data analysis and an interest in infectious disease research in a public health context. The candidates will have a track-record of publishing in peer-reviewed, academic journals and excellent communication skills.The post is full-time until October 2021.Please include a CV and supporting statement with details of how you meet the knowledge, skills and experience required.Informal enquiries to Prof. Andrew Rambaut ([email protected]).Salary: £32,548 - £38,833 per annumVacancy Ref: 044074Closing Date:23-JUL-2018 at 5pm GMTFor further particulars and to apply for this post please click on the 'apply' button below

7908| Czech Technical University in Prague| Nanostructure coating design by advanced magnetron sputtering| Applications are invited for a postdoctoral research fellow in the Advanced Materials Group (Department of Control Engineering, Faculty of Electrical Engineering, Czech Technical University in Prague) to work on the nanostructure coating design of coatings reducing friction and wear.SHORT DESCRIPTION OF THE PROJECT: The project core objective is the reduction of friction by simulation-aided design of nanostructured sputtered coatings. We will explore various nanostructures to achieve novel low-friction surfaces by controlled diffusion or adaptive structure. The project is carried out in close collaboration with a world-leading industrial partner and combines different theoretical approaches in order to allow a rational design of surfaces and lubricants for automotive applications. The project will as well link activities at the Czech Technical University in Prague with the University of Southampton, UK.OBJECTIVES:The goal is to develop the process (based on dc, r.f., and HiPIMS sputtering) leading to specific structural and topographical features reducing friction in various contact conditions. Three material families will be investigated: i) carbon-based films, ii) nitrides with accelerated/inhibited metal diffusion, and iii) oxides and oxinitrides. Initial deposition will be performed at laboratory scale deposition chamber and selected solution will be up-scaled in an industrial-size device.JOB REQUIREMENTS: Successful candidates must have a PhD in Physics, Chemistry, Materials Science, or closely related disciplines. Experience with magnetron sputtering and thin film characterization (structure, mechanical properties) is mandatory. Previous experience on the HiPIMS (theoretical or experimental) is welcome. Good knowledge of English, both written and oral, is compulsory.ABOUT THE GROUP:Advanced Materials Group is formed of experimentalists and computationalists working on coatings and low-dimensional systems for various applications. The group is well-established and consists of dynamic and motivated researchers leading international collaborations on broad interdisciplinary topics. In case of exceptional results, postdocs can be promoted to assistant professor (tenure track).CONTRACT DETAILS: The salary will be competitive (approx. 25,000 EUR/year plus employer bonus). The positions are initially for 2 years and can be prolonged upon mutual agreement. Project duration is 5 years.HOW TO APPLY: The call is open immediately and the position will be filled as soon as a proper candidate is found – the starting date is expected to be no later than Q4/2018. Applications must include a brief description of research interests and relevant experience, the CV with publications, and at least two letters of recommendation of academic referees. Inquiries and applications shall be sent to: [email protected]

7889| UKRI Medical Research Council, Laboratory of Molecular Biology| NMR Spectroscopist (Maternity Cover) - Structural Studies - Dr Stefan Freund| NMR Spectroscopist (Maternity Cover)Starting Salary £27,906 - £33,305 MRC Laboratory of Molecular Biology, Cambridge UKWe are seeking to appoint an experimental NMR spectroscopist to provide maternity cover until the 5th May 2019 and to strengthen our efforts in biological solution-state NMR spectroscopy. As a core support facility, NMR spectroscopy contributes to a large range of projects, including protein complexes, membrane proteins, protein dynamics and interaction studies. NMR often complements other structural (X-ray crystallography, cryoEM) and biophysical methods through collaboration. The LMB NMR Facility operates 5 Bruker spectrometers ranging from 500 to 800 MHz, all equipped with TCI cryoprobes and the latest hardware and software configuration.You will have a PhD in a relevant subject, hands on experience with the running of modern NMR spectrometers and/or the analysis of NMR data and a track record of published research using NMR spectroscopy. Preference will be given to those who have experience of working in a collaborative and multidisciplinary environment.For informal discussions please contact Stefan Freund:[email protected] MRC Laboratory of Molecular Biology is a research institute within UK Research and Innovation (UKRI). UKRI is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at www.ukri.org.Working for UKRI MRC provides a whole host of benefits including a defined benefit pension scheme, excellent holiday entitlement (40 ½ days including bank holidays & privilege days) and Benenden Healthcare membership. You will also have access to employee shopping/travel discounts, on site sport and social facilities, as well as salary sacrifice cycle to work schemes and childcare vouchers.Closing date: 21st June 2018Final appointments will be subject to a pre-employment screening.The Medical Research Council is an Equal Opportunities Employer who participates in the Disability Confident scheme.

7922| ITS Ireland| PostDoc on the predicted impact of Connected and Autonomous Vehicles on the Irish roads network| ITS Ireland is commissioning one, 12-month, postdoctoral bursary award for 2018-2019(commencing in September 2018). Proposals which address the predicted impact of Connected and Autonomous Vehicles (CAVs) on the Irish national road network are invited. The objectives of this research are to understand how CAVs will affect road transport in Ireland and to identify what needs to be done now in order to maximise the opportunities that CAVs will bring. The focus of the research will be divided into three strands: the first two will be examinations of the anticipated impact of CAVs on road safety and traffic management; the third strand will be an assessment of policies and structures that would need to be put in place in order to optimally manage the introduction of CAVs. Candidates should refer to www.itsireland.ie for further details.

7915| Open University, School of Life, Health and Chemical Sciences| Post doctoral research associate (PDRA)| The STEM Faculty at the Open University, UK has been awarded funding from Alzheimer’s Research UK (ARUK) for a 12 month pilot project entitled “Maternal obesity and risk of developing Alzheimer’s disease: the Framingham Heart Study”. The post holder will carry out statistical analysis of large human cohort datasets related to intergenerational effects of metabolic disease and cognitive function.Successful applicants will hold a PhD in Statistics or Biostatistics and have relevant experience. Preference will be given to applicants with a background in neuroscience or metabolic disorders.Start date: 02 September 2018End date: 31 August 2019Informal enquiries can be addressed to [email protected] see website for additional details and for information on how to apply: http://www.open.ac.uk/about/employment/vacancies/post-doctoral-research-associate-14811Deadline for applications is noon on 30 July 2018.

7920| University of Birmingham| Research Fellow - 59439| Full Time33 monthsPost is open to: External and internal candidatesGrade 7Salary:Full time starting salary is normally in the range £29,799 to £38,832. With potential progression once in post to £41,212 a year.Additional Information:The University of Birmingham is a very international environment, and applicants from all over the world, with English language skills, are welcome. Please visit our websites: http://www.biosciences-labs.bham.ac.uk/hidalgo/Alicia_Hidalgo_Lab_Home.html https://www.birmingham.ac.uk/staff/profiles/biosciences/hidalgo-alicia.aspxAn enthusiastic post-doctoral scientist will investigate a novel mechanism of structural synaptic plasticity, to understand how structural changes in neurons - axonal terminals, dendrites and synapses - underlie nervous system function and behaviour, from locomotion to learning. We recently discovered that kinase-less Trk-family receptors interact with Toll-family receptors to regulate structural synaptic plasticity in response to neurotrophin ligands (Ulian-Benitez, Bishop et al 2017 PLoS Genetics). We will work out how this novel pathway regulates structural synaptic plasticity, using the fruit-fly Drosophila as a model organism, and cutting edge developmental neuroscience approaches, ranging from molecular genetics to neural circuitry and behavioural assays, recording and altering neuronal activity with electrophysiology and optogenetics, microscopy in fixed specimens, in time-lapse and with activity reporters. Candidates should have a PhD or equivalent research experience in Neuroscience, Biology, Genetics, Biochemistry or related disciplines. Experience working with Drosophila and/or neuroscience methods would be an advantage. This is a 33 month project (with a possibility of an extension), based in the laboratory of Dr Alicia Hidalgo, at the University of Birmingham. It will also involve collaborations with Prof. Richard Baines (University of Manchester), Dr Matthias Landgraf (University of Cambridge), Dr Marta Zlatic (Janelia Research Campus, US) and Prof. Bertram Gerber (Leibniz Institut für Neurobiologie, Germany), including some stays in their labs to carry out experiments and/or for training. Person Specification• First degree in Neuroscience/Life Sciences/Biological Sciences/Genetics/Cell Biology/Chemistry/Biochemistry or related disciplines, and either a PhD or equivalent research experience in one of such related disciplines • High level analytical capability • Ability to communicate complex information clearly • Fluency in relevant techniques or methods, and ability to contribute to developing new ones, within the disciplines mentioned above (e.g. molecular biology, cell biology, microscopy, imaging, genetics, optogenetics, behaviour, neurophysiology, Drosophila, etc.). • Experience either working with Drosophila or neuroscience would be desirable • Ability to assess resource requirements and use resources effectively • Understanding of and ability to contribute to broader management/administration processes

7901| Helix Technologies| Associate Antenna Designer| Helix Technologies Ltd is seeking to recruit an electro-magnetic specialist to work at its offices located on the Harwell Science Campus, Oxfordshire, UK, to design antennas using dielectric-loaded, multi-filar helix antenna technology.Our compact, ceramic-based, helix antennas out-perform incumbent antenna technologies and are particularly suited to applications where there is a need for precise positioning, robust telecommunications links and downward pressure on device size, weight and power, for example Internet of Things (IoT), autonomous vehicles (GNSS and DSRC V2X), drone delivery platforms, personal body-worn devices and Machine-to-Machine (M2M) communicationsThe Company is currently developing GNSS and V2X antenna products for the driverless car market. However, dielectric-loaded, multi-filar helix antenna technology lends itself to many other demanding telecommunications and GNSS-enabled applications, such as M2M, IoT and drone-delivery platforms, and we anticipate substantial interest from these market sectors in the future.The work will primarily involve using the CST Studio Suite electro-magnetic simulation programme to design dielectric-loaded, helix antennas for telecommunications and GNSS applications. The ideal candidate will have experience of researching electro-magnetic or antenna problems, most likely at post-graduate level, and have experience in one or more of the following areas:-• Research experience of solving electro-magnetic science/engineering problems• Experience of electro-magnetic simulation – preferably with the CST Microwave Studio Suite tool-set• Experience of antenna design using dielectric materials and antenna array design would be advantageous• Experience of using SolidWorks to create engineering drawings• Good knowledge of antenna theory• Willingness to locate to the Harwell Science CampusThe work will be carried out under the supervision of Helix Technologies’ Technical Director - Dr. Oliver Leisten.

7904| Politecnico di Milano| Postdoctoral positions at Politecnico di Milano-Department of Mechanical Engineering in thermal measurement and computer science for biomedical challenges| Postdoctoral positions at Politecnico di Milano-Department of Mechanical Engineering in thermal measurement and computer science for biomedical challengesContracts duration: 2 years with a possible renewal for a third year.DescriptionApplicants are invited for Postdoctoral positions at Politecnico di Milano (PoliMI - Department of Mechanical Engineering) funded by the ERC Starting Grant “Laser Ablation: SElectivity and monitoRing for OPTImal tuMor removal”.We are looking for candidates with a strong research potential, interested in investigating thermometry and predictive mathematical models of biomedical phenomena.The research activities defined by the LASER OPTIMAL project focus on the development of a technological platform for laser ablation in cancer treatment, and in particular: physical simulations for treatment settings planning, nanoparticles-mediated laser ablation to improve the treatment selectivity, real-time monitoring of the thermal effects, intra-operative adjustment of the pre-planned settings.Candidates requirementsProfile 1Particular attention will be paid to candidates who already have some experience working on one or more of the following topics: optical-thermal response of laser irradiated tissue, thermal measurements, measurement of physiological parameters, design and manufacturing of fiber optic based sensors for biomedical applications (e.g., fiber Bragg gratings), laser systems, signal processing.PhD in Biomedical/Mechanical/Electronic Engineering, Physics, and related disciplines;interest in the aspects of temperature measurement for biomedical purposes, and in design, development and characterization of measuring systems.Profile 2Particular attention will be paid to candidates who already have some experience working on one or more of the following topics: heat transfer modeling in biological tissue, optical-thermal response of laser irradiated tissue, medical image processing (e.g., MRI, CT), software development for real-time physics simulation of the human body, real-time simulations, virtual reality, computer science for medical applications.PhD in Computer Science, Biomedical Engineering, Physics, and related disciplines;interest in the aspects of physical modeling for biomedical purposes, and in biomedical imaging processing.For both profiles, the following features are highly desired:working knowledge of Matlab;demonstrated record of relevant experience with publications and training;fluent English (spoken and written);experience in lab management (e.g., quotation inquiry, negotiation with suppliers) will be also positively considered.Contract detailsThe successful candidates will join the research unit “Mechanical and Thermal Measurements” at the Department of Mechanical Engineering of Politecnico di Milano (PoliMi). PoliMi provides excellent research conditions, in a quiet environment inside the active Milan region: in the QS ranking by subject PoliMi is the first Italian University in several research areas (Including Mechanical Engineering), among the first 6 European Universities in Europe and among the first 20 all over the world.The postdoctoral researcher will have the opportunity to attend and present research results in conferences and symposia, to collaborate with national and international partners (in France and United States) and to visit their laboratories. The monthly net salary is highly competitive (approx. 1,800 €) and can be adjusted in function of the experience.Applications should be sent by email (all documents in English) to the contact below, and include:CV;list of publications and oral communications;motivation letter (max 1 page);summary of previous research activities (max 2 pages);contact details for two references.Contact [email protected] SaccomandiPI of the LASER OPTIMAL ProjectAssociate Professor