8139| The Health Concierge/ University of Westminster, School of Life Sciences| Research Fellow in Mitochondrial Bioenergetic Index| 12 MONTHS, FIXED TERMSalary Negotiable for Correct Candidate The role: It is now possible to collect a small volume of blood from subjects and assess basal mitochondrial function in the form of a mitochondrial bioenergetic health Index (MBHI) and subsequently determine how it varies in response to different life-style conditions. The aim of this project is for the Research Fellow to implement this MBHI to monitor changes in bioenergetics in free-living individuals. This, coupled with other risk markers, will enable us to stratify subjects against a population’s optimal health curve, and thus provide them with a measurable point on a scale. It will be a benchmark for each individual to work from, in order to achieve or maintain optimal health. The ultimate aim is to create a novel data management system that will integrate current and future health outputs that are presently collected and presented individually to customers.Responsibilities:Developing and implementing the MBHI. You will, in conjunction with Prof Bell, design and carry out the experiments, analyse results and create Standard MBHI Curves.Work closely with all stakeholders to maximise the impact of the results and integrate them into practical data management systemCollating, presenting and producing project updates/reports to SME stakeholders and colleagues Support the SME for knowledge transfer with project updates and maintenance/support documentation/videos.Essential criteria: Minimum 2.1 BSc in biochemistry or related subject and experience in:Isolation of PBMC and mitochondria Assessing mitochondrial function Use of SeaHorse system Participant recruitmentUnderstanding of research method, analysis and interpretation of resultsCreation of practical and ease of use of Data Bases and ModellingAbility to:Communicate well to non-specialist audience Work well under pressure Desirable criteria:PhD with experience in mitochondrial metabolism and cell biologyKnowledge of programming as you will be working closely with the SME to implement the use of “personalised avatars” for visualization of health outputSome expertise in “R” or “Python” for statistical analysisAbout KEEP+:This post forms an integral role in a Knowledge Exchange and Embed Partnerships (KEEP+) project. It provides you with the opportunity to work with a company to deliver a strategic project and also have access to university expertise and support.To apply for this vacancy please click above. Further information can be found in the job description and person specification, which can be accessed through link below. Closing date: 2 November 2018Applicants are encouraged to apply as early as possible as applications will be reviewed and candidates interviewed on a rolling basis.Informal enquiries may be made by email to ([email protected]) or ([email protected])Administrative contact (for queries only): [email protected] Please note: We are unable to accept applications by email. All applications must be made online. CV’s in isolation or incomplete application forms will not be accepted. We are fortunate to receive a large number of applications for our vacancies. Regrettably, we are not able to provide feedback to those job applicants who are not shortlisted, as it simply would not be manageable to do so. Applicants who require a certificate of sponsorship to work in the UK are encouraged to familiarise themselves with the UKVI Tier 2 certificate of sponsorship requirements in order to ensure they meet the eligibility criteria. For further information please visit the UKVI webpage on the Gov.uk website.Embracing diversity and promoting equality

8123| Dublin City University, School of Chemical Sciences| Postdoctoral Researcher in Liposomes and Proteoliposomes| We are seeking a postdoctoral scientist with a PhD in chemistry, biochemistry, molecular biology or related field and experience in preparation and study of liposomes, proteoliposomes or supported lipid bilayers. The researcher will contribute to projects focussed on assaying integrin aggregation and membrane transporter function in model cell membranes. Experience in preparation and handling of liposomes or proteoliposomes is essential. In particular, candidates with experience of working with giant unilammelar vesicles (GUVs) and their electroformation are particularly sought. Experience in biophysical analysis of biomembranes is an advantage and candidates with experience in confocal fluorescence microscopy and fluorescence correlation spectroscopy and/or in electrochemical impedance spectroscopy are particularly encouraged to apply. The candidate should have a PhD in chemistry, physical chemistry or related discipline with significant experience in preparation of plasmonic metal substrates for SERS and in computation analysis (numerical simulation) of plasmonic fields of SERS substrates. The candidate should have experience in Raman spectroscopy/microscopy and experience in fluorescence microscopy/lifetime imaging would also be an advantage.

8120| Sidney Kimmel Cancer Center/Thomas Jefferson University, Department of Cancer Biology| Postdoctoral Researcher in Ras-tumor biology| We are currently seeking highly motivated and independent postdocs to study how oncogenic RAS signaling cooperates with stress stimuli to promote tumorigenesis. The lab has recently described that cancers that are driven by the mutated KRAS gene can mobilize a stress protective response through the engagement of the stress-sensing machinery known as stress granules. The successful candidate will utilize 2D and 3D cell culture, mouse models, high-resolution/high-content microscopy, biochemistry and molecular biology to decipher the molecular networks through which stress granules determine the capacity of mutant KRAS cells to cope with stress, and their role in KRAS-driven pancreatic cancer and the establishment of a tumor-promoting microenvironment. For further information please visit www.grabockalab.comRequirementsCandidates should have a recent PhD or MD/PhD degree in cancer biology, cell biology, biochemistry, or a closely related field, have proven ability to work independently as well as within a team, be able to multi-task, and communicate effectively. Only candidates with first author publications from their terminal degree will be considered.Interested applicants should submit a cover letter explaining their scientific interest, their previous experience, and a CV to Dr. Elda Grabocka at [email protected] The last page of the CV should include the contact information (e-mail address and phone number) for three references.

8113| The Institute of Cancer Research, Division of Cancer Therapeutics| Post-Doctoral Training Fellow Biologist - Regulation of HSF1 in cancer cells| The Cancer Research UK Cancer Therapeutics Unit, within the Division of Cancer Therapeutics, is a multidisciplinary 'bench to bedside' centre, comprising around 160 staff dedicated to the discovery and development of novel therapeutics for the treatment of cancer. The Cancer Therapeutics Unit’s exciting goal is to discover high quality drug candidates for validated biological targets and to progress these candidates to clinical trial. All the scientific disciplines are in place to make this possible. Our biologists work alongside world-class chemists and drug metabolism specialists focusing on new molecular targets emerging from human genome and ground breaking cell biology research. This is an exciting and fast moving area of cancer research, and offers the opportunity to work within a multi-disciplinary environment using state-of-the-art techniques and equipment.We are seeking two highly motivated Biologists to work in our Signal Transduction and Molecular Pharmacology (STMP) Team with Dr Paul Clarke & Professor Paul Workman, located in well-equipped laboratories in Sutton, South London. The successful applicants will use molecular, biochemical and cellular techniques to explore to validate potential molecular targets that regulate the transcriptional response to heat shock and other stresses in cancer cells.Candidates should possess a PhD in Biochemistry, Molecular Biology or Cell Biology, have developed a range of skills through experience in these areas and be able to work in an interdisciplinary environment towards the goal of performing cellular and biochemical assays required for pathway analysis. Knowledge of cancer research and familiarity with contemporary approaches to drug discovery, molecular target validation is desirable.Appointment will be to a Post-Doctoral Training Fellowship with starting salary in the range of £30,715 to £39,082 p.a. inclusive (based on previous experience). Appointment will be for 3 years in the first instance, and benefits from a contributory defined benefit pension scheme and generous leave entitlement. To find more information and to apply online please follow the link to ICR Careers webpage

8094| MRC Laboratory of Molecular Biology, Neurobiology| Postdoctoral Scientists| Postdoctoral ScientistStarting Salary £30,464 to £33,305 per annumMRC Laboratory of Molecular Biology, Cambridge, UKThe MRC Laboratory of Molecular Biology is a world leader in biological research, with an expanding scientific programme dedicated to understanding gene function in health and disease. It provides an unsurpassed environment for both young and established researchers. Scientists are drawn to the LMB from all over the world, creating a lively and international community for the exchange of ideas and technical innovation.We are looking to recruit a biochemist with expertise and interests in protein expression, purification, enzymology and structural or biophysical studies. You will join Dr Anne Bertolotti’s pioneering research programme, which focuses on innovative approaches to rescue cells from protein misfolding, a condition at the origin of many human diseases, including neurodegenerative diseases. One of such approaches consists in selective inhibition of phosphatases, an important discovery because phosphatases were thought to be undruggable before this work (see Tsaytler et al., 2011, Science, 332, 91-4; and Das et al., 2015, Science, 348, 239-242, Carrara, M., Sigurdardottir, A., & Bertolotti, A. (2017). Nat Struct Mol Biol, 24(9), 708–716). Krzyzosiak, A., Sigurdardottir, A. et al., A. (2018). Cell, 174(5), 1216–1228.e19.)You will join a strong inter-disciplinary team at the LMB which has broad expertise extending from biochemistry, structural, chemical, molecular and cell biology through to transgenic animals models of degenerative diseases. We also have an excellent record of innovative basic research leading to applications in medicine, a passion for science and a commitment to explore the unknown.Further information about the position may be obtained from Dr Anne Bertolotti– email: [email protected] You will be ambitious, creative and fearless. You will have a PhD molecular or cell biology due to complete doctoral studies within 6 months of applying. Relevant experience is required and this must be best attested by at least one impactful publication. Experience with mouse models is essential. An interest in signaling and/or stress responses/protein quality control is desirable. The MRC Laboratory of Molecular Biology is a research institute within UK Research and Innovation (UKRI). UKRI is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at www.ukri.org.Working for UKRI MRC provides a whole host of benefits including a defined benefit pension scheme, excellent holiday entitlement (40 ½ days including bank holidays and privilege days) and Benenden Healthcare membership. You will also have access to employee shopping/travel discounts, on site sport and social facilities, as well as salary sacrifice cycle to work schemes and childcare vouchers.To apply and access full details of the vacancy please visit our job board at https://mrc.tal.net/vx/lang-en-GB/appcentre-1/candidate/postings/1052. If you are unable to apply online please contact us at [email protected] date: 28 October 2018Final appointments will be subject to a pre-employment screening.The Medical Research Council is an Equal Opportunities Employer who participates in the Disability Confident scheme.

8098| University College Dublin, UCD School of Electrical and Electronic Engineering| Senior Power Systems Researcher in Distributed Energy Resources, UCD School of Electrical and Electronic Engineering (Temporary)| Applications are sought for a Senior Researcher position to work on the topics of active distribution system management, distributed energy resources (DER) and control of power electronics devices in the distribution system. The position will be based in the UCD Energy Institute and UCD School of Electrical and Electronic Engineering.For this position, we are seeking a candidate to work on the development of methods to assess the system level benefits of different control approaches for power electronics devices in the distribution system, including power electronics transformers and smart inverters for distributed energy resources. The ideal candidate would be expected to have a thorough knowledge of power systems and specifically distribution systems, including experience with the modelling of DER such as electrical energy storage, wind generation and photovoltaic systems.Responsibilities will include working with other members of the team and with our project partners to deliver on the overarching scientific goals of the project.See Job Description for more details.Salary: €43,394 - €47,255 per annum.Closing Date: 17.00hrs (Local Irish Time) on 1 November 2018.Applications must be submitted by the closing date and time specified. Any applications which are still in progress at the closing time of 17:00hrs (Local Irish Time) on the specified closing date will be cancelled automatically by the system. UCD are unable to accept late applications.UCD do not require assistance from Recruitment Agencies. Any CVs submitted by Recruitment Agencies will be returned.Prior to application, further information (including application procedure) should be obtained from the Work at UCD website: https://www.ucd.ie/workatucd/jobs/.

8127| ICR| Post Doctoral Training Fellow – Chemical Proteomics| Closing Date: 06/11/2018Location: Sutton and LondonDivision: Cancer TherapeuticsTeam: Translational Cancer DiscoveryVacancy Type: Full timeType of Contract: Fixed TermLength of Contract: 2 yearsHours per Week: 35Salary Range: £30,410 - £42,634The Institute of Cancer Research, London, is one of the world’s most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. We provided the first convincing evidence that DNA damage is the basic cause of cancer, laying the foundation for the now universally accepted idea that cancer is a genetic disease. Today, The Institute of Cancer Research (ICR) leads the world at isolating cancer-related genes and discovering new targeted drugs for personalised cancer treatment.Under the leadership of our Chief Executive, Professor Paul Workman FRS, the ICR is ranked as the UK’s leading academic research centre. Together with our partner The Royal Marsden, we are rated in the top four cancer centres globally.The ICR is committed to attracting, developing and retaining the best minds in the world to join us in our mission – to make the discoveries that defeat cancer.The Cancer Research UK Cancer Therapeutics Unit, within the Division of Cancer Therapeutics, is a multidisciplinary 'bench to bedside' centre, comprising around 160 staff dedicated to the discovery and development of novel therapeutics for the treatment of cancer. The Cancer Therapeutics Unit’s exciting goal is to discover high quality drug candidates for validated biological targets and to progress these candidates to clinical trial. All the scientific disciplines are in place to make this possible. Our biologists work alongside world-class chemists and drug metabolism specialists focusing on new molecular targets emerging from human genome and ground breaking cell biology research. This is an exciting and fast moving area of cancer research, and offers the opportunity to work within a multi-disciplinary environment using state-of-the-art techniques and equipment.This Unit is now under the leadership of Professor Rajesh Chopra who has previously held senior leadership positions at AstraZeneca and Celgene and academic positions in the UK in haematological oncology and stem cell transplantation.The Functional Proteomics unit is located at the Chester Beatty Labs, in Chelsea. This unit is led by Dr Jyoti Choudhary, also the Head of Mass Spectrometry Unit at the ICR.The unit has leading edge Proteomics and Metabolomics technologies, including several Orbitrap and Time of Flight mass spectrometers.This vibrant team are comprised of experimental and computational scientists that develop quantitative mass spectrometry to characterise diverse protein attributes. The team have expertise in large scale proteomics for basic and clinical applications. The unit is located within the Division of Cancer Biology.Starting salary in the region of £30,410 to £42,634 pa inclusive (based on previous experience). Appointment will be for 24 months in the first instance.

8121| University of Southampton, School of Biological Sciences| Postdoctoral Research Fellow in Mammary Stem Cell Biology| Full Time - Fixed Term for 3 yearsReference: 1061818BJA Research Fellow position is available in the laboratory of Mammary Stem Cell Biology & Breast Cancer headed by Dr. Salah Elias at the School of Biological Sciences (SoBS) – University of Southampton (UoS), to study the mechanisms of asymmetric cell division during mammary gland development and homeostasis. The position is available for 3 years tenable from February 2019, funded by the Medical Research Council (MRC).The ProjectOur lab focusses on studying the mechanisms that regulate mammary stem cell fate and dynamics in normal development and breast cancer. This exciting project is a collaboration between our group and Dr. Philip Greulich group based at the Department of Mathematical Sciences at UoS. It will employ combined cutting-edge in vivo single-cell lineage tracing, quantitative three-dimensional (3D) high-resolution imaging and single-cell RNA-sequencing as well as mathematical/computational modelling to (1) identify novel mechanisms that control mitotic spindle orientation in mammary stem cells; and (2) determine how these mechanisms influence cell fate outcomes in the differentiating mammary epithelium. The outcomes of this collaborative project are expected to provide important novel insight into the identity, dynamics and potential of mammary stem cells. The Successful CandidateWe are looking for a creative, ambitious and skilled Postdoctoral Researcher Scientist willing to challenge an innovative project by adopting a pro-active attitude and an analytical approach, with a strong interest in interdisciplinary collaboration. You will be responsible for the development of the project, which includes experimental design, data collection and interpretation. You will work in collaboration with Dr. Greulich group who will use mathematical modelling to compare the generated experimental data with predictions from stochastic models for cell fate dynamics, and test the project’s hypotheses via Bayesian inference. You are also expected to contribute to new ideas for research projects, develop ideas for writing grant proposals, prepare scientific reports, write up results for publication in international peer-reviewed journals, assist other members of our group or people working on collaborative projects to become familiar with new methodologies, act as a source of information and advice on scientific protocols. You will hold a PhD* or equivalent professional qualifications and experience in epithelial stem cell and/or cancer biology (or related field). A strong evidence of proficiency in cell biology and quantitative advanced microscopy in vivo is necessary. You will have experience in animal models and have a personal licence to work with rodents or be prepared to obtain such a licence via attendance of in-house courses. Experience in molecular biology techniques including Next Generation Sequencing is desirable. Basic understanding of computational/mathematical modelling would be advantageous. You will be friendly and have excellent interpersonal skills with a desire to communicate with other researchers whilst maintaining the highest level of professionalism at all times.The Environment At SoBS, we use cutting-edge technologies for innovative research to define the basis of human health and disease, and develop interventions that benefit peoples’ lives. There is a strong interdisciplinary research focus bringing together researchers from Biological and Medical Sciences, Computer Sciences, Physics and Mathematical Sciences with experimental work housed in a £45 million building that encompasses cutting-edge research infrastructures. SoBS offers a supportive and dynamic research environment, with comprehensive training and career development opportunities. You will have full access to all resources and undertake appropriate training in the use of the equipment of our state-of-the-art core facilities to accomplish your studies. SoBS has an outstanding Stem Cell and Developmental research theme, in which our group is perfectly embedded, with excellent potential for collaborations that extend to the closely located Cancer Sciences where breast cancer research is very active. You will thrive within a unique international, stimulating and challenging research environment, with an outstanding international research seminar series in addition to Stem Cells and Quantitative Biology-centred meetings co-organized by SoBS and Mathematical Sciences. The proximity of SoBS and Mathematical Sciences and the specialized expertise that each contributes provides a unique environment needed to achieve the maximum impact of this project.For informal enquiries, please contact Dr Salah Elias [email protected] in the first instance.It is anticipated that interviews will take place at the end of November 2018.Equal Opportunities and BenefitsSoBS holds an Athena SWAN Silver Award, demonstrating commitment to equal opportunities and gender balance in the workplace. The University of Southampton has a generous maternity policy and onsite childcare facilities; employees are able to participate in the childcare vouchers scheme. Other benefits include state-of-the-art on-campus sports, arts and culture facilities, a full programme of events and a range of staff discounts.Application ProcedureClosing Date: 5th November 2018. However, we encourage early applications as we will be reviewing applications on an on-going basis. Therefore the advert may close before the deadline if suitable candidates are identified. First review date: 29th October 2018How to Apply: You should submit your completed application form online at www.jobs.soton.ac.uk. Please include (1) a cover letter outlining your scientific interests, describing how you meet the requirements of the position, and an outline of future goals; (2) a curriculum vitae, (3) contact information for at least two references. References are requested along with your application, so please allow time for these to be received prior to the close date, to assist the department with shortlisting. If you need any assistance, please call Samantha Stubbs (Recruitment Team) on +44 (0) 23 8059 4046. Please quote vacancy reference number 1061818BJ on all correspondence.*Applications will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification. The title of Research Fellow will be applied upon successful completion of the PhD. Prior to the qualification being awarded the title of Senior Research Assistant will be given..

8106| Queen Mary University of London, School of Biological and Chemical Sciences| Postdoctoral Research Assistant| An ERC-funded Postdoctoral Research Assistant position is available at Queen Mary University of London (QMUL) in Dr José M (Chema) Martín-Durán’s group, to work on the epigenetic regulation of conditional and autonomous development in spiral cleaving animals (e.g. annelid worms, molluscs, and nemerteans). Queen Mary is one of the top research-led universities in the UK and was ranked 9th among the UK multi-faculty universities in the Research Excellence Framework (REF 2014). All postdoctoral researchers are part of the QMUL Doctoral College, which provides support with high-quality training and career development activities.This research position will focus on identifying the maternal factors that control early spiral cleavage and account for the differences in cell fate specification modes observed among spiralian lineages. The project will involve the use of multiple animal species, and combine proteomics and single-cell transcriptomics with classic embryological approaches. The findings from the project will untangle the molecular regulation of early spiral cleavage and provide a general understanding of the evolution of novel strategies of early development.The ideal candidate for the position will have a PhD in developmental and/or evolutionary biology, with significant experience in embryological methods (in vitro fertilisation, embryo culture, in situ hybridisation, imaging), general molecular biology techniques (PCR, gene cloning, etc) and bioinformatics (RNA-seq data analyses, fluid use of command line tools and R). A track record of peer-reviewed publications is essential. Experience in single-cell RNA-seq experimental and computational methods and/or proteomics is highly desirable. The post is funded by the European Research Council (ERC) and is a full-time position. The post is available for a period 2 years, with possibility a 1 year extension thereafter. The start date is 1st February 2019 or as soon as possible thereafter. The salary is dependent on qualifications, skills and experience and is in the range of £33,615 - £39,483 per annum, inclusive of London allowance. Benefits include 30 days annual leave and a pension scheme. Candidates must be able to demonstrate their eligibility to work in the UK in accordance with the Immigration, Asylum and Nationality Act 2006. Where required this may include entry clearance or continued leave to remain under the Points Based Immigration Scheme.Informal enquiries are welcomed and encouraged, and may be made to Dr Martín-Durán via e-mail at [email protected] For information about the School of Biological and Chemical Sciences and the Martín-Durán lab, please visit martinduranlab.com and http://www.sbcs.qmul.ac.uk To apply, please click on the link below.Application enquiries should be directed to [email protected] closing date for applications is 31 October 2018. Interviews will be held shortly thereafter. Valuing Diversity & Committed to Equality

8135| Max Planck Institute for Biophysical Chemistry, Department of Theoretical and Computational Biophysics, Computational Biomolecular Dynamics Group| Open Postdoc Positions in Computational Biophysics, Max Planck Institute for Biophysical Chemistry, Goettingen, Germany| The Computational Biomolecular Dynamics Research Group (Prof. Dr. Bert de Groot) at the Department for Theoretical and Computational Biophysics aims at an understanding of the physics and function of proteins, protein complexes, and other biomolecular structures at the atomic level through molecular dy-namics simulations and invites applications for positions as postodc for the following projects:-- Markov State Modeling of Permeation in Ion Channels-- Collective Dynamics Underlying Channel Permeation-- Design of Protein Mutations Affecting Channel GatingThe successful candidate has a keen interest in computational molecular biophysics and skills in structural biology, physical chemistry, statistical mechanics and biocomputing and hold a PhD in any of these or a related field.The payment and benefits are based on the German TVöD guidelines. The Postdoc positions are limited to two years with a possible extension. The Max Planck Society is committed to increasing the number of individuals with disabilities in its workforce and therefore encourages applications from such qualified individuals. Please submit your application including cover letter (explaining background and motivation), CV, transcripts, and publication record preferably via e-mail as one single PDF file with reference to the code number (35-18) to [email protected] Planck Institute for Biophysical Chemistry Department of Theoretical and Computational Biophysics Computational Biomolecular Dynamics Research GroupProf. Dr. Bert de GrootAm Fassberg 11D-37077 GöttingenPhone : +49 551 201 2308Web: https://www.mpibpc.mpg.de/degrootor http://www3.mpibpc.mpg.de/groups/de_groot/index.html

8125| National Oceanography Center (NOC)| Postdoctoral Research Associate| Postdoctoral Research AssociateUKRI - NERC NOCSouthampton£28,200 - £32,430Full time/Part Time (hour’s subject to negotiation)Fixed term (2 years) contract length variable for part time rolesAbout UsThe Natural and Environmental Research Council (NERC) is a partner organisation within UK Research and Innovation (UKRI). UKRI is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, and a vision to ensure the UK maintains its world-leading position in research and innovation. The National Oceanography Centre (NOC), part of NERC, is a national research organisation, delivering integrated marine science and technology from the coast to the deep ocean and is one of the top five institutions of its kind in the world.BenefitsIn return for your talents, we offer a competitive remuneration package, including a RCUK pension scheme, 30 days annual leave with a further 14 Public/local days off and free car-parking. Opportunities for further training and development are supported.About the roleWe are looking to recruit an enthusiastic and motivated scientist, with experience in physical oceanography and its role in climate, to carry out Lagrangian analyses of drifter trajectories (observed and modelled). You will diagnose freshwater pathways originating in Arctic and Greenland melt water using drifters deployed on the shelves around Greenland. You will then use the observed and modelled pathways and additional datasets, to identify processes by which freshwater crosses off the continental shelf and into the deep ocean in the subpolar North Atlantic.You will work as part of the TERIFIC team (a new EU-funded project called Targeted Experiment to Reconcile Increased Freshwater with Increased Convection), within the Ocean Circulation and Processes subgroup at the National Oceanography Centre in Southampton. Key responsibilities: • analysis of numerical simulations of drifters to plan drifter deployments and contribute to the TERIFIC scientific aims• drifter deployments and related logistics for TERIFIC fieldwork• quality control of drifter dataset• analysis of drifter dataset and related observational-based products to investigate the pathways of freshwater around Greenland and the Labrador Sea in order to contribute to the TERIFIC scientific aims• publish and present results from the TERIFIC project.About youYou will have a PhD in physical oceanography with experience in oceanographic observations and their analysis. You must have a good knowledge of ocean dynamics and its role in climate systems with strong quantitative skills, good communication and interpersonal skills and a publication record appropriate to your career stage.You should have an interest in presenting your results at national and international conferences.Participation in fieldwork expeditions (anticipated for 2019/20) is desirable but not required.How to ApplyApplicants are required to include a cover letter outlining their suitability for this role. Applications are handled by UK SBS; to apply please click the apply button. Applicants who are unable to apply online should contact us by telephone on +44 (0)1793 867000.The closing date for applications is 11th November 2018.

8114| University of Bath, Computer Science| Research Associate in Visual Computing and Machine Learning| We are looking for highly motivated individual to work on an exciting new collaboration using visual computing and machine learning in the context of digital healthcare. The 'RA Flare Profiler' is an Innovate UK funded project between the University of Bath, Royal United Hospitals Foundation Trust and Living With Ltd to provide transformational new capability to Living With’s existing 'Living With Rheumatoid Arthritis' (LWRA) product. Utilising Machine Learning technologies, the proposed flare profiler will provide a very granular view of a patient's RA profile, based largely on data collected from the patient from the convenience of their own home and comparing it to a wider patient population, significantly reducing the need for hospital-based specialist tests.Flare frequency, duration and severity are key indicators of disease progression in Rheumatoid Arthritis (RA). While undergoing a flare, patients are exposed to systemic inflammation that can be permanently damaging. Current clinical management of RA is based on either pre-scheduled appointments (e.g. at 6, 12 or 18 month intervals) or emergency clinics, with data collection based around these interactions. There is no regular mapping of fluctuations in disease severity, with the unpredictability of acute flare-ups being a key feature of the disease despite as many as 78% of patients recalling flares monthly or more regularly. As such, it remains very difficult to make informed treatment plans, because of the unpredictability of the disease and patients' fluctuating symptoms.The Rheumatoid Arthritis Flare Profiler will allow every Rheumatoid Arthritis patient to receive a more intelligent and personalised treatment plan, based on the early and continuous reporting of their flare up data and its comparison against the aggregated RA profiler model. This will reduce some of the costs associated with an unexpected deterioration in health and wellbeing. It will do this by combining new and existing mobile phone based methods of capturing individual disease activity with advanced artificial intelligence technology to provide a profiling model that can inform treatment planning.You will join the Centre for the Analysis of Motion, Entertainment Research and Applications (CAMERA) is a thriving EPSRC funded research centre based at the University of Bath (Departments of Computer Science and Health). The aim is to create research impact in the areas of Entertainment, Human Performance Enhancement (e.g. Sport and Training) and Assistive Technologies (e.g. Health). CAMERA has several existing world-class partners across Entertainment, Sport and Health, including: The Imaginarium, The Foundy, The Ministry of Defence (MoD), British Maritime Technologies (BMT) and British Skeleton.This is a fixed-term position with an expected duration of up to 15 months.For an informal discussion about the role, please contact Professor Darren Cosker ([email protected]) or Matthew Young ([email protected]).We are working to improve the gender balance within the department’s population and particularly welcome applications from women.Closing date: Sunday 28 October 2018 Interview date: To be confirmed

8136| The University of Texas MD Anderson Cancer Center, Epigenetics and Molecular Carcinogenesis| Postdoctoral Fellowship in Signal Transduction and Proteomics| A funded postdoctoral fellowship is available in the laboratory of Dr. Mark Bedford at The University of Texas MD Anderson Cancer Center. Research on arginine methylation and the use of protein domain microarrays to interrogate signaling pathways will be carried out in the Department of Epigenetics and Molecular Carcinogenesis in Smithville. The department (near Austin, TX) is one of MD Anderson’s largest and most successful fundamental research departments. For more information, see the laboratory website:https://www.mdanderson.org/research/departments-labs-institutes/labs/bedford-laboratory.htmlMD Anderson offers many benefits and career training opportunities for postdoctoral fellows:https://www.mdanderson.org/education-training/clinical-research-training/postdoctoral-training.htmlRequirements:Applicants should have a recent Ph.D. degree in biochemistry or a highly related field, one or more first-authored publications in highly regarded scientific journals, and proven proficiency in written and spoken English. Experience with mammalian cell culture, recombinant protein purification and Western blot analysis is an advantage.Application process:Applicants should send a cover letter, CV, statement of research interest and the contact information of three references to Dr. Mark Bedford ([email protected]) with the subject line “Postdoc Application in Signaling & Arrays”.M. D. Anderson Cancer Center is an equal opportunity employer and does not discriminate on basis of race, color, national origin, gender, sexual orientation, age, religion, disability or veteran status except where such distinction is required by law. All positions at The University of Texas M. D. Anderson Cancer Center are security sensitive and subject to examination of criminal history record information. Smoke-free and drug-free environment.

8122| University of Southampton, Ecology and Evolution| Research Fellow in Evolutionary Genomics| Location: Highfield CampusSalary: £30,395 to £31,302 Full Time Fixed Term (3 years)Closing Date: Friday 02 November 2018Reference: 1064218BJWe seek a Research Fellow to investigate “The contribution of plasticity to adaptive divergence: domestication as a model”. The NERC/BBSRC co-funded project provides support for 3 years from 7th January 2019 to work with Dr Mark Chapman in the Ecology and Evolution group at the University of Southampton (https://www.southampton.ac.uk/biosci/about/staff/mc1c12.page), co-supervised by Dr Tom Ezard in Ocean and Earth Science (https://www.southampton.ac.uk/oes/about/staff/te1e12.page).The goal of this project is to study the evolution of plasticity, comparing crops to their wild relatives, as a model for understanding the genetic basis and role of plasticity in adaptive divergence and the early emergence of new taxa.You will have a PhD* or equivalent professional qualification in a relevant subject area, with a strong evolutionary and genomic/transcriptomic component. A high level of competence in bioinformatics is required, with relevant experience demonstrated by publications in peer reviewed journals where possible. Competency in statistics and programming would be advantageous and experience with plants desirable. You should be a highly motivated scientist, capable of contributing to developing your own research project, a good team worker and an excellent communicator.Chapman and Ezard are interested in fusing evolutionary theory with experimental approaches, and you would be expected to contribute intellectually to the development of the project. A broad interest in evolution as a whole is required. The current work will use extensive greenhouse and laboratory experiments coupled with transcriptome, whole genome and methylome analyses to decipher the contribution of plasticity to adaptive divergence. It offers excellent potential for publishing in high impact journals and developing independent research agendas.You will assume leadership on the project, including significant intellectual contribution, setting up experiments and involvement in making decisions about current and future research directions. You will work in a highly collaborative atmosphere supported by state-of-the-art research facilities that will provide a perfect environment to carry out the project.For informal enquiries, please email Dr Mark Chapman ([email protected]) in the first instance. *Applications will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification. The title of Research Fellow will be applied upon successful completion of the PhD. Prior to the qualification being awarded the title of Senior Research Assistant will be given.Equal Opportunities and Benefits: Biological Sciences holds an Athena SWAN Silver Award, demonstrating commitment to equal opportunities and gender balance in the workplace. We aim to be an equal opportunities employer and welcome applications from all sections of the community. Please note that applications from agencies will not be accepted.The University of Southampton has a generous maternity policy and onsite childcare facilities; employees are able to participate in the childcare vouchers scheme. Other benefits include state-of-the-art on-campus sports, arts and culture facilities, a full programme of events and a range of staff discounts.Please include a covering letter, full CV and names and contact details for three referees in your application.Application Procedure:You should submit your completed online application form at http://www.jobs.soton.ac.uk/www.jobs.soton.ac.uk. The application deadline will be midnight on the closing date stated above. If you need any assistance, please call Sam Stubbs (Recruitment Team) on +44 (0)23 8059 4046. Please quote reference 1064218BJ on all correspondence.

8111| The Medical Research Council (MRC)| Policy and Governance Manager| Policy and Governance ManagerUKRI - MRCSwindon£37,789 - £41,988Full timeOpen endedAbout UsThe Medical Research Council (MRC) is a partner organisation within UK Research and Innovation (UKRI). UKRI is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, and a vision to ensure the UK maintains its world-leading position in research and innovation. The MRC is a publicly-funded organisation dedicated to improving human health. We support research across the entire spectrum of medical sciences, in universities and hospitals, and in our own units and institutes.BenefitsChoosing to come to work at the MRC means that you will have access to a whole host of benefits from a defined benefit pension scheme and excellent holiday entitlement to access to employee shopping/travel discounts and salary sacrifice cycle to work scheme, as well as the chance to put the MRC and UKRI on your CV in the future.About the roleThe overall purpose of this role is to support the Director of Policy, Ethics and Governance and the Executive Chair in:• developing and implementing research related policy• ensuring the MRC contributes effectively to policy discussions relevant to medical and health research both within UKRI and nationally• maintaining good governance within the MRC, meeting reporting requirements within UKRI and supporting effective operation of the MRC Council and any subcommittees.Key responsibilities:• provide support on policy relating to animals in research and engage with research funders and other stakeholders, including the Animals in Science Regulation Unit• work with the communications team to support transparency about animal research• keep abreast of policy discussions and publications relating to research integrity and reproducibility, advise senior staff and contribute to development of relevant policy or initiatives, working with other stakeholders as required• manage the review and updating of policy and governance documents• engaging with staff from across MRC, other research councils and NC3Rs to support policy implementation and identify issues that need addressing• managing the secretariat for MRC’s Council and the MRC Ethics, Regulation and Public Involvement Committee, including planning agendas, producing papers, managing members’ induction and appraisal, and ensuring conflicts of interest are identified and managed appropriately• represent MRC in cross-UKRI discussions on governance, research policy and ethics.About youYou will be educated to PhD level or equivalent and will have significant experience of working in research, research policy or research management in life sciences or a health related field. You should have experience of organising senior-level meetings and writing minutes and reports as well as having previous involvement in working with external stakeholders and representing your organisation. You must have excellent communication skills and experience of dealing with people across all levels of management, including executive and senior management. You should have knowledge of university and medical research sectors and be familiar with the policy environment for science and research. How to ApplyApplicants are required to include a cover letter outlining their suitability for this role. Applications are handled by UK SBS; to apply please click the apply button. Applicants who are unable to apply online should contact us by telephone on +44 (0)1793 867000.The closing date for applications is 21st October 2018.

8095| Institute of Cancer Research| Post-Doctoral Training Fellow Biologist – Regulation of protein synthesis initiation| The Institute of Cancer Research, London, is one of the world’s most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. We provided the first convincing evidence that DNA damage is the basic cause of cancer, laying the foundation for the now universally accepted idea that cancer is a genetic disease. Today, The Institute of Cancer Research (ICR) leads the world at isolating cancer-related genes and discovering new targeted drugs for personalised cancer treatment.Under the leadership of our Chief Executive, Professor Paul Workman FRS, the ICR is ranked as the UK’s leading academic research centre. Together with our partner The Royal Marsden, we are rated in the top four cancer centres globally.The ICR is committed to attracting, developing and retaining the best minds in the world to join us in our mission – to make the discoveries that defeat cancer.Vacancy Description Astex PharmaceuticalsAstex Pharmaceuticals is a world leader in innovative drug discovery and development. The company has successfully applied its proprietary Fragment-Based Drug Discovery (FBDD) platform to generate multiple new drug candidates that are progressing in clinical development and is recognised as having world leading expertise in structural biology and FBDD. Astex’s Sustaining Innovation Post-Doctoral Research Program aims to maintain and further enhance the company’s excellent scientific culture by fostering basic research in areas of interest to drug discovery. The program also seeks to promote interactions between scientists from the biotech sector and academic experts in areas of common research interest.The Cancer Research UK Cancer Therapeutics Unit, within the Division of Cancer Therapeutics, is a multidisciplinary 'bench to bedside' centre, comprising around 160 staff dedicated to the discovery and development of novel therapeutics for the treatment of cancer. The Cancer Therapeutics Unit’s exciting goal is to discover high quality drug candidates for validated biological targets and to progress these candidates to clinical trial. All the scientific disciplines are in place to make this possible. Our biologists work alongside world-class chemists and drug metabolism specialists focusing on new molecular targets emerging from human genome and ground breaking cell biology research. This is an exciting and fast moving area of cancer research, and offers the opportunity to work within a multi-disciplinary environment using state-of-the-art techniques and equipment. We are seeking a highly motivated Biologist to work in our Signal Transduction and Molecular Pharmacology Team with Dr Paul Clarke, located in well-equipped laboratories in Sutton, South London. The successful applicant will use molecular, biochemical and cellular techniques to explore the regulation of protein synthesis initiation in cancer cells and to validate potential molecular targets for cancer therapy identified by the team. The project is in collaboration with Astex Pharmaceuticals and it is expected that the successful applicant will also have access to Astex’s Sustaining Innovation Post-Doctoral Research Program. Candidates should possess a PhD in Biochemistry, Molecular Biology or Cell Biology, have developed a range of skills through experience in these areas and be able to work in an interdisciplinary environment towards the goal of performing cellular and biochemical assays required for pathway analysis. Knowledge of cancer research and familiarity with contemporary approaches to drug discovery, molecular target validation is desirable. Appointment will be to a Postdoctoral Training Fellowship with starting salary in the range of £30,715 to £39,082 p.a. inclusive based on relevance of skills and experience. Appointment will be for 2 years in the first instance, and benefits from a contributory defined benefit pension scheme and generous leave entitlement. Further information can be found in the full job description at https://icr.tal.net/vx/appcentre-ext/brand-0/candidate/so/pm/1/pl/1/opp/537-Post-Doctoral-Training-Fellow-Biologist-Regulation-of-protein-synthesis-initiation/en-GBWe consider all applications on merit and have a strong commitment to enhancing the diversity of our staff.

8118| University College Dublin, UCD School of Computer Science| UCD Post- Doctoral Research Fellow Level 1, UCD School of Computer Science (Temporary)| UCD together with Origin Enterprises Plc have recently established a new research programme, CONSUS, focussed on the application of precision agriculture to crop production with a particular emphasis on optimisation of agri-food production systems leading to more efficient food production with lower environmental impacts.The particular focus of this research post is to work with the research team to manage the various field trials that will be undertaken to validate the CONSUS platform. This will be done in partnership with other stakeholders within CONSUS. The candidate will be responsible for developing the test cases using an appropriate methodology and set of protocols and evaluation strategies to assess the effectiveness of each trial using a suite of established metrics, including performance and usability metrics.The successful candidate will have the opportunity to work in a dynamic research environment and will actively contribute to exciting and cutting-edge multi-disciplinary research.Experience gained in this post will significantly further the career development and training of the successful candidate.Salary: €35,324 per annum.Closing Date: 17.00hrs (Local Irish Time) on 26th October 2018.Applications must be submitted by the closing date and time specified. Any applications which are still in progress at the closing time of 17:00hrs (Local Irish Time) on the specified closing date will be cancelled automatically by the system. UCD are unable to accept late applications.UCD do not require assistance from Recruitment Agencies. Any CVs submitted by Recruitment Agencies will be returned.Prior to application, further information (including application procedure) should be obtained from the Work at UCD website: https://www.ucd.ie/workatucd/jobs/.

8085| Medical Research Council, London Institute of Medical Sciences| MRC Post Doctoral Research Scientist| MRC Post Doctoral Research ScientistFunctional Gene Control groupMRC Band 4 Salary £35,340 - £38,181 pa inclusive*London, UKA 3-year postdoctoral position is open in the Functional Gene Control group at MRC London Institute for Medical Sciences (LMS) led by Dr Mikhail Spivakov (https://lms.mrc.ac.uk/research-group/functional-gene-control/ and http://functionalgenecontrol.group). We combine experimental and computational approaches to study the logic of gene regulation, with a particular emphasis on the function of DNA elements such as enhancers in gene regulatory networks and on human primary cells as experimental systems. Examples of our recent work include Freire-Pritchett et al., eLife 2017, Javierre et al., Cell 2016, and the Chicago R package for Capture Hi-C analysis (Cairns et al., Genome Biol 2016).You will have a PhD, a strong background in a biomedical science or quantitative discipline (mathematics, statistics, physics, computer science), as well as prior experience in generating and/or interrogating data from high-throughput genomics assays. Competence in the analysis of chromosomal interactions and cis-regulatory networks is particularly relevant, and a track record in devising novel experimental and/or computational techniques is desirable. The ideal applicant will have a dual wet- and dry-lab expertise, but strong candidates from either one of these backgrounds are also encouraged to apply. You will join an international, multidisciplinary team within a collaborative and stimulating research environment, with strong links with other groups at the LMS and beyond.Informal inquiries can be addressed to Dr Mikhail Spivakov ([email protected]).Choosing to come to work at the MRC (part of UKRI) means that you will have access to a whole host of benefits from a defined benefit pension scheme and excellent holiday entitlement to access to employee shopping/travel discounts and salary sacrifice cycle to work scheme, as well as the chance to put the MRC and UKRI on your CV in the future.For full details of this post and to complete an online application, visit https://mrc.tal.net/vx/lang-en-GB/appcentre-1/candidate/postings/1044 and upload your CV, names and contacts of two scientific references along with a covering letter stating why you are applying for this role (providing evidence against the requirements of the job and your motivation). Please quote reference number LMS – 926.Closing date: 27 October 2018The MRC London Institute of Medical Sciences is a research institute within UK Research andInnovation. UK Research and Innovation is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at www.ukri.org *Salary quoted is inclusive of London weighting. Additional allowances comprise a £1,000 lump sum Settlement Allowance plus a yearly Training Allowance of £850 in the first year, paid in monthly installments. The Training Allowance increases to £1,300 in year two, and £1,800 in the third year.

8086| Agri-Food and Biosciences Institute Northern Ireland (AFBI)| Principal Economist (Grade 7)| REF: IRC233235SALARY: £48,226 to £52,857DEPARTMENT: Agri-Food and Biosciences Institute Northern Ireland (AFBI)LOCATION: AFBI Headquarters, Newforge Lane, BelfastThe demand for economic analysis across the Agri–Food industry for both policy and strategy development has increased significantly in AFBI. As such AFBI are now seeking to appoint a Principal Economist to lead on key research initiatives in support of the local, national and international Agri-Food Sector.Further appointments may be made from this competition should AFBI positions become vacant which have similar duties and responsibilities.For more detailed information and to apply, please go to www.nicsrecruitment.org.ukPerson specification: https://irecruit-ext.hrconnect.nigov.net/resources/documents/i/r/c/irc233235---final-cib_141610.pdfAlternatively, an application pack can be requested by contacting:HRConnect, PO Box 1089, The Metro Building, 6-9 Donegall Square South, Belfast, BT1 9EW. Telephone: 0800 1 300 330. Email: [email protected] requests must include your name, address and reference number IRC233235Completed application forms must be returned to arrive not later than 12:00 noon (UK time) on Monday 22nd October 2018.Applications are particularly welcomed from Roman Catholics and Females as these groups are currently under-represented within AFBI.AFBI is an Equal Opportunities EmployerALL APPLICATIONS FOR EMPLOYMENT ARE CONSIDERED STRICTLY ON THE BASIS OF MERIT

8130| University of Calgary, Faculty of Environmental Design and Cumming School of Medicine| 2-Year Post-Doctoral Fellowship –Geospatial Analysis of Human Radon Gas Exposure in Relation to Environmental Design Metrics| Context: Our goal is to understand the geospatially distinct environmental design contributors of radiation exposure from radon gas as a source of lung cancer, and develop solutions to protect the population. Lung cancer is the leading cause of cancer death in North America and is overwhelmingly caused by chronic inhalation of tobacco smoke and/or radioactive radon gas. Radon is the primary cause of lung cancer in never smokers, encompassing 10,000-40,000 Canadians per decade. Canada contains many radon-generating regions, and Canadians have constructed population centres across all of them, although this does not mean that all buildings contain high radon. Indeed, there are three factors needed to incur hazardous radon exposure: (i) a geologic source and pathway (upwards) for radon, (ii) environmental design metrics that actively draw up and concentrate radon and (iii) human behaviour that prolongs exposure or increases radon concentrations. The postdoctoral scholar will aim to identify modifiable behaviours and environmental design practices influencing chronic radon exposure in our changing world and define engineering and community intervention solutions applicable within the Canadian context to eliminate radon as a source of cancer in the future. The mentorship team encompasses leading expertise in radon and cancer biology (Goodarzi) merged with architecture and environmental design (Taron). Qualifications: The ideal candidate will be a scholar with a PhD (within 3 years of completing PhD; ABD will be considered) in geography, architecture, urban studies, public heath, energy efficiency or a related field, who will maintain a high degree of research productivity and extend existing capacities of the growing Evict Radon research confederation of scholars. They will demonstrate a high degree of self-direction and creativity, and will ideally be familiar with the Canadian funding landscape. This position is initially for two years, with the possibility of renewal pending successful funding applications.Application closing date: November 14th, 2018Position start date: early 2019Salary: $55 000 per year plus benefits To apply, Please send your CV, a cover letter outlining broad research interests and contributions, and a one-page research proposal pertaining to the themes above, to [email protected] and [email protected] by end of November 14th, 2019. Successful short-listed applicants will be required to provide letters of reference and may be invited for an in-person or video-conference interview.

8082| Austrian Academy of Sciences, Research Center for Molecular Medicine| Postdoc: Bioinformatics, Deep Learning and Digital Medicine| We are recruiting an ambitious computational postdoc who wants to pursue groundbreaking research at the interface of computational biology and digital medicine, including deep neural networks and bioinformatic methods development. The scope of potential projects comprises machine learning in medicine (genomics, imaging, etc.), development and application of new methods for multimodal time series analysis, or massive-scale single-cell sequencing analysis.Our group at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences in Vienna combines wet-lab biology/medicine (cancer, immunology, epigenetics etc.) with advanced bioinformatics including deep learning. We work closely with physicians at the Vienna General Hospital & Medical University of Vienna to advance precision medicine.The ProjectThe successful candidate will develop and apply advanced machine learning technology (e.g., deep neural networks, kernel methods, time series analysis, causal modeling) to discover fundamental mechanisms of biology and to advance personalized medicine. Potential applications include single-cell sequencing in cancer, 3D reconstruction of tumors, epigenetic landscapes, mobile health technology, and pattern discovery in heterogeneous biomedical data. Our location on one of the largest medical campuses in Europe ensures direct relevance to medicine, while close ties with the Max Planck Institute for Informatics (Germany) provide first-hand access to a top-notch computer science environment.The CandidateWe are looking for ambitious candidates who want to build a scientific career in bioinformatics and/or artificial intelligence research and its applications in biology and medicine. A strong candidate would have a strong background in the quantitative sciences (computer science, bioinformatics, statistics, mathematics physics, engineering, etc.). We will also consider applicants with a background in biology or medicine who have strong quantitative skills and a keen interest in pursuing computational projects (a combination with wet-lab research is possible).The Lab (http://epigenomics.cemm.oeaw.ac.at/)The Medical Epigenomics Lab at CeMM pursues an interdisciplinary and highly collaborative research program aimed at understanding the cancer epigenome and establishing its utility for precision medicine. The lab is internationally well-connected and active in several fields:• Epigenomics. Many diseases show widespread deregulation of epigenetic cell states. As members of the Human Cell Atlas and the International Human Epigenome Consortium, we use epigenome sequencing to dissect the epigenetic basis of cancer and immunity.• Technology. Groundbreaking biomedical research is often driven by new technologies. Our lab is therefore heavily invested into technology development, including single-cell sequencing, CRISPR screens, and epigenome editing.• Bioinformatics. New algorithms and advanced computational methods allow us to infer epigenetic cell states from large datasets, in order to reconstruct the epigenetic landscape of cellular differentiation and complex diseases.• Diagnostics. New technologies (genome sequencing, mobile devices, etc.) provide important information for personalized medicine. We develop and validate assays and algorithms for translating the value of digital medicine into routine clinical practice.The Principal Investigator (https://scholar.google.com/citations?user=9qSsTcIAAAAJ)Christoph Bock is a principal investigator at CeMM. His research focuses on epigenetics, bioinformatics, and high-throughput technology (single-cell sequencing, CRISPR) in the context of personalized medicine. He is also a guest professor at the Medical University of Vienna, scientific coordinator of the Biomedical Sequencing Facility at CeMM, and adjunct group leader for bioinformatics at the Max Planck Institute for Infor-matics. He has been a principal investigator of the BLUEPRINT project (in the International Human Epigenome Consortium), and he co-founded Genom Austria, a citizen science project that is the Austrian partner in the International Network of Personal Genome Projects. He is a member of the Young Academy of the Austrian Academy of Sciences (since 2017) and recipient of several major research awards, including the Max Planck Society’s Otto Hahn Medal (2009), a New Frontier Group grant by the Austrian Academy of Sciences (2015-2020), an ERC Starting Grant (2016-2021), and the Overton Prize of the International Society of Computational Biology (2017).The Institute (http://www.cemm.at/)CeMM is an international research institute of the Austrian Academy of Sciences and a founding member of EU-LIFE. It has an outstanding track record of top-notch science (last few years: >10 papers in Nature/Cell/Science/NEJM, >25 papers in Nature/Cell sister journals) and medical translation. With just over a hundred researchers, CeMM provides a truly collaborative and personal environment, while maintaining critical mass and all relevant technologies. Research at CeMM focuses on cancer, inflammation, and immune disorders. CeMM is located at the center of one of the largest medical campuses in Europe, within walking distance of Vienna’s historical city center. A study by “The Scientist” placed CeMM among the top-5 best places to work in academia world-wide (http://the-scientist.com/2012/08/01/best-places-to-work-aca-demia-2012). Vienna is frequently ranked the world’s best city to live. It is a United Nations city with a large English-speaking community. The official language at CeMM is English, and more than 40 different nationalities are represented at the institute. CeMM promotes equal opportunity and harbors a mix of different talents, backgrounds, competences, and interests. Postdocs at CeMM are paid according to the Austrian Science Fund’s salary scheme, which amounts to an annual gross salary slightly above EUR 50,000.Please apply online(https://cemm.jobbase.io/job/7u3y2q4d) with cover letter, CV, academic transcripts, and contact details of three referees.Applications will be reviewed on a rolling basis. Any application received by 3 November 2018 will be considered. Start dates are flexible.

8138| Queen Mary University of London, School of Biological and Chemical Sciences| Postdoctoral Research Assistant| A Postdoctoral Research Assistant position is available at Queen Mary University of London (QMUL) in Dr Fabrice Caudron’s group, to work on the role of prion-like proteins in cell fate and memory. Queen Mary is one of the top research-led universities in the UK and was ranked 9th among the UK multi-faculty universities in the Research Excellence Framework (REF 2014). All postdoctoral researchers are part of the QMUL Doctoral College, which provides support with high-quality training and career development activities. This research position will focus the mechanisms of condensation and function of several prion-like proteins in response to pheromone and during yeast replicative ageing. This involves classical molecular biology and yeast genetics techniques in order to perform 3D time-lapse microscopy. In addition, you will establish the production and use of microfluidics chips to perform full lifespan imaging of yeast cell, in collaboration with other research groups. You will also start translating this research to zebrafish embryos. The ideal candidate for the position will have a PhD in cell and molecular biology, with significant experience in yeast cell biology. A track record of peer-reviewed publications is essential. Experience in the production of microfluidic chips would be an asset. The post is BBSRC funded and is a full-time position, available for a period of 3 years. The start date is 1st December 2018. The salary is £33,615 per annum and is inclusive of London allowance. Benefits include 30 days annual leave and a pension scheme. Candidates must be able to demonstrate their eligibility to work in the UK in accordance with the Immigration, Asylum and Nationality Act 2006. Where required this may include entry clearance or continued leave to remain under the Points Based Immigration Scheme.Informal enquiries are welcomed, and may be made to Dr Fabrice Caudron via e-mail at [email protected] For information about the School of Biological and Chemical Sciences, please visit http://www.sbcs.qmul.ac.uk To apply, please click on the link below.Application enquiries should be directed to [email protected] closing date for applications is 15 November 2018. Interviews will be held shortly thereafter. Valuing Diversity & Committed to Equality

8129| University of Calgary, Departments of Ecosystem and Public Health/Comparative Biology and Experimental Medicine| Developing treatment strategies for prion and Alzheimer's disease| We are seeking applicants for a prestigious "Eyes High" Post Doctoral Fellowship (https://ucalgary.ca/research/eyes-high-postdoc) at the University of Calgary in Alberta, Canada. Highly motivated candidates have the opportunity to join an ambitious team at the Calgary Prion Research Unit (https://vet.ucalgary.ca/calgary-prion-research-unit/) to work on a project entitled "Expanding the use of cellulose ethers for the treatment of prion and prion-like diseases". This project aims to investigate the underlying effect of cellulose ethers on prion and amyloid-propagation. The goal is to develop novel therapeutic strategies for prion and Alzheimer’s disease by using single or combination drug treatment in vitro and in vivo. We offer the opportunity to independently develop a research project, to participate in undergraduate and graduate student supervision and training, to attend national and international conferences. Required qualifications are a PhD in cell biology, biochemistry, neuroscience or a related field. Experience with cell culture and primary neuronal cultures and in particular in vitro, cell culture and mouse models of Alzheimer's disease or prion diseases would be an asset. The position is funded for 2 years. Competitive applicants are expected to apply for external fellowships. In addition to working in an inspiring research environment, the city of Calgary offers many recreational amenities from sports to cultural events. It is located closely to the Rocky Mountains and Banff National Park, providing a unique variety of hiking trails and skiing areas.Please send your application containing a statement of previous research experience and publication record, a statement why you are interested in joining our groups, a CV and a list of three referees to Dr. Sabine Gilch ([email protected]; www.ucalgary.ca/gilchlab/ ), Associate Professor and Canada Research Chair in Prion Disease Research and/or Dr. Hermann Schaetzl, Professor in Prion Biology and Immunology ([email protected]; https://www.ucalgary.ca/schatzl_prionlab/; https://www.ncbi.nlm.nih.gov/pubmed/?term=schatzl+h )

8093| MRC Laboratory of Molecular Biology, Neurobiology| Postdoctoral Scientist| Starting Salary £30,464 - £33,305 per annum Fixed Term 3 Years MRC Laboratory of Molecular Biology, Cambridge, UKThe MRC Laboratory of Molecular Biology is a world leader in biological research, with an expanding scientific programme dedicated to understanding gene function in health and disease. It provides an unsurpassed environment for both young and established researchers. Scientists are drawn to the LMB from all over the world, creating a lively and international community for the exchange of ideas and technical innovation.We are looking to recruit a molecular biologist with expertise in mouse work, and in particular, experience in conducting behavioral studies, preferably with expertise in mouse models of neurodegenerative diseases and diabetes. You will join Dr Anne Bertolotti’s pioneering research programme, which focuses on innovative approaches to rescue cells from protein misfolding, a condition at the origin of many human diseases, including neurodegenerative diseases. One of such approaches consists in selective inhibition of phosphatases, an important discovery because phosphatases were thought to be undruggable before this work (see Tsaytler et al., 2011, Science, 332, 91-4; and Das et al., 2015, Science, 348, 239-242, Carrara, M., Sigurdardottir, A., & Bertolotti, A. (2017). Nat Struct Mol Biol, 24(9), 708–716). Krzyzosiak, A., Sigurdardottir, A. et al., A. (2018). Cell, 174(5), 1216–1228.e19.)You will join a strong inter-disciplinary team at the LMB which has broad expertise extending from biochemistry, structural, chemical, molecular and cell biology through to transgenic animals models of degenerative diseases. We also have an excellent record of innovative basic research leading to applications in medicine, a passion for science and a commitment to explore the unknown.Further information about the position may be obtained from Dr Anne Bertolotti– email: [email protected] You will be ambitious, creative and fearless. You will have a PhD molecular or cell biology due to complete doctoral studies within 6 months of applying. Relevant experience is required and this must be best attested by at least one impactful publication. Experience with mouse models is essential. An interest in signaling, stress responses and protein quality control is desirable. You will be awarded a three-year MRC Career Development Fellowship/MRC Postdoctoral Training Scheme, which is a training and development position for a postdoctoral scientist who has recently completed doctoral studies or is moving into a new research discipline.The MRC Laboratory of Molecular Biology is a research institute within UK Research and Innovation (UKRI). UKRI is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at www.ukri.org.Working for UKRI MRC provides a whole host of benefits including a defined benefit pension scheme, excellent holiday entitlement (40 ½ days including bank holidays and privilege days) and Benenden Healthcare membership. You will also have access to employee shopping/travel discounts, on site sport and social facilities, as well as salary sacrifice cycle to work schemes and childcare vouchers.To apply and access full details of the vacancy please visit our job board at https://mrc.tal.net/vx/lang-en-GB/appcentre-1/candidate/postings/1049. If you are unable to apply online please contact us at [email protected] date: 28 October 2018Final appointments will be subject to a pre-employment screening.The Medical Research Council is an Equal Opportunities Employer who participates in the Disability Confident scheme.

8117| University College Dublin, UCD School of Computer Science| UCD Post- Doctoral Research Fellow Level 1, UCD School of Computer Science (Temporary)| The postdoctoral researcher will contribute to the development of a suite of intelligent decision support services that will aid agronomists and farmers in the management of their crops. In particular, the researcher will contribute to the research, design and implementation of the CONSUS software and data architecture that will facilitate the integration and seamless interoperability of software components, services and data and will facilitate the transformation of data into knowledge that can be utilised by the decision support services.The software and data architecture will support the harvesting, curation, conflation and access to diverse data together with actuation of data deriving components. This architecture will incorporate IoT (Internet of Things) technologies and will underpin and make provision for Intelligent decision support services offered to the end user.The particular focus of this research post is delivering intelligent decision-support services for both agronomists and farmers offering contextualised/personalised advice and support for what if scenario modelling.The successful candidate will have the opportunity to work in a dynamic research environment and will actively contribute to exciting and cutting-edge multi-disciplinary research. Experience gained in this post will significantly further the career development and training of the successful candidate.Salary: €35,324 per annum.Closing Date: 17.00hrs (Local Irish Time) on 26th October 2018.Applications must be submitted by the closing date and time specified. Any applications which are still in progress at the closing time of 17:00hrs (Local Irish Time) on the specified closing date will be cancelled automatically by the system. UCD are unable to accept late applications.UCD do not require assistance from Recruitment Agencies. Any CVs submitted by Recruitment Agencies will be returned.Prior to application, further information (including application procedure) should be obtained from the Work at UCD website: https://www.ucd.ie/workatucd/jobs/.

8131| University of Iowa, Carver College of Medicine - Department of Pediatrics| Postdoctoral Research Scholar| About the Stead Family Department of Pediatrics and University of Iowa Stead Family Children’s HospitalThe Stead Family Department of Pediatrics is a national leader in pediatric medicine. The Department's mission is to provide outstanding care to the children of Iowa and beyond by being a leader in state-of-the-art clinical care to children, performing cutting-edge research to find new treatments and cures for childhood illnesses, and educating the next generation of pediatric health care providers. The Department comprises the medical and research staff of UI Stead Family Children’s Hospital. UI Stead Family Children’s Hospital is one of the nation’s top-ranked pediatric care and research institutions, and Iowa’s only comprehensive children’s hospital. A new free-standing Children’s Hospital opened in 2017. Division of Pediatric Pulmonary Medicine, Allergy, and ImmunologyThe Division of Pulmonary Medicine, Allergy, and Immunology seeks a Post-doctoral Scholar to assist with research efforts on the preclinical development of novel gene therapies for cystic fibrosis. We are broadly interested in host-pathogen interactions, defense mechanisms, and epithelial responses to bacteria and viruses. The lab has a major interest in the pathogenesis and treatment of cystic fibrosis. Additional studies are investigating interactions between airway epithelia and specific viral and bacterial pathogens.The laboratory is performing a variety of gene transfer studies using lentiviral and transposon vectors. We have developed novel lentiviral vector pseudotypes that target receptors on the apical surface of airway epithelia. We are also exploring other nucleic acid based interventions including RNA interference and gene editing for therapeutic purposes. In addition we are investigating genomics approaches such as the connectivity map to identify small molecules to rescue CFTR function. A long-term goal is to develop vector systems with that can be successfully used in children to treat or prevent CF lung disease by gene addition or gene repair.Position Summary The candidate will assist with research efforts on the preclinical development of novel gene therapies for cystic fibrosis. We seek a candidate with proven ability to work independently and collaboratively to achieve project goals. The candidate will be expected to generate novel ideas to overcome barriers to vector delivery. The ultimate goal is the generation of products that will benefit patients. Position Responsibilities• Test novel viral vectors by quantifying gene transfer or gene editing efficiencies in both in vitro and in vivo models.• Use molecular biology to optimize vectors by enhancing genome packaging and optimizing titer.• Conduct molecular biological research on novel viral vectors to enhance the efficiency of target cell transduction and perform studies of functional expression of therapeutic transgenes.• Generate, manage, evaluate, and maintain critical data in a highly organized manner. Author technical reports, method transfer documents, and prepare scientific presentations as needed.• Provide project leadership to ensure that research objectives are achieved in a timely manner. Education Requirements• Ph.D is required, preferably in the biological sciencesExperience Requirements• Strong background in cell biology and molecular biology. • A demonstrated relevant publication and/or funding record.• Strong record of conducting molecular virology or viral vector research using multiple approaches to elucidate molecular mechanisms of virus-cell interactions.• Ability to effectively prioritize parallel laboratory activities and communicate the progress of these activities.• Ability to work effectively in a collaborative team environment.• Excellent written and verbal communication skillsHighly Desired Qualifications• Experience with adenoviral vector systems is highly desirable.• Prior experience conducting small and large animal research is highly desirable.• Experience manipulating high molecular weight bacterial plasmids is highly desirable.

8083| Austrian Academy of Sciences, Research Center for Molecular Medicine| Postdoc: Cancer, Immunology, and/or Single-cell Epigenomics| We are recruiting an ambitious wet-lab postdoc who wants to pursue groundbreaking re-search in the field of cancer and immunology. The scope of potential projects includes functional dissection of immune processes in primary tumors and transgenic mouse models, development and application of high-throughput technologies including CRISPR screens and single-cell epigenomics, and systematic engineering of cell-based therapies (CAR T cells).Our group at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences in Vienna combines wet-lab biology (epigenomics, single-cell sequencing, drug screening, flow cytometry, imaging) and bioinformatics. We work closely with physicians at the Vienna General Hospital & Medical University of Vienna to advance precision medicine.The ProjectRecent technological progress opens up many opportunities for groundbreaking research in cancer and immunology. Our lab has established powerful assays for single-cell mapping and high-throughput functional dissection, which we are applying to understand the role of immune (de)regulation in cancer, and to develop the scientific foundations for a new generation of powerful and flexible CAR T cell therapies. We are open for a broad range of project ideas that combine a solid foundation in immunology / cancer research with latest technological advances.The CandidateWe are looking for ambitious candidates who want to build a scientific career in basic biology and/or biomedical research. A strong candidate would have a background in immunology, cancer research, or related areas (cell-based therapies, functional genomics, etc.) and a keen interest in interdisciplinary collaboration. We are fully equipped and experienced with wet-lab and computational work, allowing candidates to get the best of both worlds and establish a unique skill set that will allow them to effectively combine wet-lab and bioinformatics in their future lab.The Lab (http://epigenomics.cemm.oeaw.ac.at/)The Medical Epigenomics Lab at CeMM pursues an interdisciplinary and highly collaborative research program aimed at understanding the cancer epigenome and establishing its utility for precision medicine. The lab is internationally well-connected and active in several fields:• Epigenomics. Many diseases show widespread deregulation of epigenetic cell states. As members of the Human Cell Atlas and the International Human Epigenome Consortium, we use epigenome sequencing to dissect the epigenetic basis of cancer and immunity.• Technology. Groundbreaking biomedical research is often driven by new technologies. Our lab is therefore heavily invested into technology development, including single-cell sequencing, CRISPR screens, and epigenome editing.• Bioinformatics. New algorithms and advanced computational methods allow us to infer epigenetic cell states from large datasets, in order to reconstruct the epigenetic landscape of cellular differentiation and complex diseases.• Diagnostics. New technologies (genome sequencing, mobile devices, etc.) provide important information for personalized medicine. We develop and validate assays and algorithms for translating the value of digital medicine into routine clinical practice.The Principal Investigator (https://scholar.google.com/citations?user=9qSsTcIAAAAJ)Christoph Bock is a principal investigator at CeMM. His research focuses on epigenetics, bioinformatics, and high-throughput technology (single-cell sequencing, CRISPR) in the context of personalized medicine. He is also a guest professor at the Medical University of Vienna, scientific coordinator of the Biomedical Sequencing Facility at CeMM, and adjunct group leader for bioinformatics at the Max Planck Institute for Infor-matics. He has been a principal investigator of the BLUEPRINT project (in the International Human Epigenome Consortium), and he co-founded Genom Austria, a citizen science project that is the Austrian partner in the International Network of Personal Genome Projects. He is a member of the Young Academy of the Austrian Academy of Sciences (since 2017) and recipient of several major research awards, including the Max Planck Society’s Otto Hahn Medal (2009), a New Frontier Group grant by the Austrian Academy of Sciences (2015-2020), an ERC Starting Grant (2016-2021), and the Overton Prize of the International Society of Computational Biology (2017).The Institute (http://www.cemm.at/)CeMM is an international research institute of the Austrian Academy of Sciences and a founding member of EU-LIFE. It has an outstanding track record of top-notch science (last few years: >10 papers in Nature/Cell/Science/NEJM, >25 papers in Nature/Cell sister journals) and medical translation. With just over a hundred researchers, CeMM provides a truly collaborative and personal environment, while maintaining critical mass and all relevant technologies. Research at CeMM focuses on cancer, inflammation, and immune disorders. CeMM is located at the center of one of the largest medical campuses in Europe, within walking distance of Vienna’s historical city center. A study by “The Scientist” placed CeMM among the top-5 best places to work in academia world-wide (http://the-scientist.com/2012/08/01/best-places-to-work-aca-demia-2012). Vienna is frequently ranked the world’s best city to live. It is a United Nations city with a large English-speaking community. The official language at CeMM is English, and more than 40 different nationalities are represented at the institute. CeMM promotes equal opportunityand harbors a mix of different talents, backgrounds, competences, and interests. Postdocs at CeMM are paid according to the Austrian Science Fund’s salary scheme, which amounts to an annual gross salary slightly above EUR 50,000.Please apply online(https://cemm.jobbase.io/job/98um8nev) with cover letter, CV, academic transcripts, and contact details of three refer-ees. Applications will be reviewed on a rolling basis. Any application received by 3 November 2018 will be considered. Start dates are flexible.

8133| University of Huddersfield, Computing & Engineering| Research Fellow| Fixed term appointment for 30 months, 37 hours per week Ref: R3952The School of Computing and Engineering is seeking to recruit a suitably qualified Research Fellow in computer science. This is a research post funded by the EPSRC UKRI Innovation Fellowship: A semantic infrastructure for advanced manufacturing (EP/S001328/1). The research theme is to build a novel semantic infrastructure for advanced manufacturing, by supporting knowledge representation, interrogation, reasoning and exchange for smart design, manufacturing and measurement of advanced products. The focus will be on the development of a toolbox to formalise knowledge in/between design, manufacturing and measurement, especially for additive manufacturing (AM).The person appointed will have a PhD in computer science-related subjects. The appointee will have a comprehensive background in the research field of knowledge management, and demonstrate an awareness of the current state of knowledge representation languages. Strong knowledge in informatics and practical experience in the development of software systems are key requirements. The appointee must also have advanced level of programming skills, including at least one or more of the following programming languages: Java, C++, C#, Scala, Haskell and Python.Candidates should have a good recent record of publication in high quality journals and be capable of developing research objectives, projects and proposals, undertaking research and evaluating outcomes independently. Candidates must also show a good experience on team work and communications for the sponsored post. The role will be required to undertake supervision of post-graduate research students, organisation of technical, progress and planning meetings. Candidates will be expected to generate high quality publications.For further details about this post and to make an application please visit http://hud.ac/er4 Closing Date: 5 November 2018Interview Date: 3 December 2018Working for Equal Opportunities.Innovative University. Inspiring Employer.

8101| University of Southampton, Earth Surface Dynamics| Research Fellow| Location: Highfield CampusSalary: £30,395 to £37,345 per annum Full Time - Fixed Term for 3 yearsClosing Date: 31/10/2018Reference: 1062718WRApplications are invited for a Research Fellow to join our project "Unnatural dynamics of flood deposits in built environments", funded by The Leverhulme Trust, on a fixed term basis for 3 years.Population and land-use pressures on river and coastal floodplains means that flood events deposit large volumes of sediment and debris in built environments. These "unnatural" flood deposits are ubiquitous, delay emergency response, and are costly to clean up. We aim to predict how spatial characteristics of built environments control the shape, scale, movement, and distribution of flood deposits. We will measure and model flood deposits in built and non-built environments to quantify and explain their differences. This project is a formative step in transdisciplinary research into how natural phenomena interact with and impact built environments.We seek a talented, quantitative, scientist who has facility and experience with numerical modelling and writing open-source code. Candidates should have a PhD* or equivalent professional qualifications and experience in a relevant subject area. A background in physical geography is preferred, but not essential: candidates with a background in cognate disciplines (e.g., physics, fluid dynamics, coastal/fluvial engineering, computer science) are encouraged to apply.The post will involve numerical modelling and data analysis, and participation in a large-scale physical experiment at the COAST Lab, a state-of-the-art facility at the University of Plymouth. Experience applying and/or modifying numerical models and analytical scripts is therefore highly desirable, but training in the necessary modelling techniques (in XBEACH) is available during the project.The successful candidate will work closely with the two principal investigators (Dr Eli Lazarus, at Southampton, & Dr Evan Goldstein, at the University of North Carolina), and will collaborate with, and help to mentor, a PhD student also working on the project. The post is hosted in the School of Geography & Environmental Science at the University of Southampton.For informal enquiries, please contact Dr Eli Lazarus ([email protected]) and/or Dr Evan Goldstein ([email protected]).It is anticipated that interviews will take place November 2018, with the intended project start date 1 January 2019.Application Procedure:You should submit your completed online application form at www.jobs.soton.ac.uk. Please ensure you include your CV and 2 page cover letter. The application deadline will be midnight on the closing date stated above. If you need any assistance, please call Geraldine Lewis (Recruitment Team) on +44 (0) 23 8059 3462. Please quote reference 1062718WR on all correspondence.*Applications for Research Fellow positions will be considered from candidates who are nearing completion of a relevant PhD qualification. The title of Research Fellow will be applied upon successful completion of the PhD. Prior to the qualification being awarded the title of Senior Research Assistant will be given.

8116| University of Southampton, Ecology and Evolution| Research Fellow in Evolutionary Genomics| Location: Highfield CampusSalary: £30,395 to £31,302 Full Time Fixed Term (3 years)Closing Date: Friday 02 November 2018Reference: 1064218BJWe seek a Research Fellow to investigate “The contribution of plasticity to adaptive divergence: domestication as a model”. The NERC/BBSRC co-funded project provides support for 3 years from 7th January 2019 to work with Dr Mark Chapman in the Ecology and Evolution group at the University of Southampton (https://www.southampton.ac.uk/biosci/about/staff/mc1c12.page), co-supervised by Dr Tom Ezard in Ocean and Earth Science (https://www.southampton.ac.uk/oes/about/staff/te1e12.page).The goal of this project is to study the evolution of plasticity, comparing crops to their wild relatives, as a model for understanding the genetic basis and role of plasticity in adaptive divergence and the early emergence of new taxa.You will have a PhD* or equivalent professional qualification in a relevant subject area, with a strong evolutionary and genomic/transcriptomic component. A high level of competence in bioinformatics is required, with relevant experience demonstrated by publications in peer reviewed journals where possible. Competency in statistics and programming would be advantageous and experience with plants desirable. You should be a highly motivated scientist, capable of contributing to developing your own research project, a good team worker and an excellent communicator.Chapman and Ezard are interested in fusing evolutionary theory with experimental approaches, and you would be expected to contribute intellectually to the development of the project. A broad interest in evolution as a whole is required. The current work will use extensive greenhouse and laboratory experiments coupled with transcriptome, whole genome and methylome analyses to decipher the contribution of plasticity to adaptive divergence. It offers excellent potential for publishing in high impact journals and developing independent research agendas.You will assume leadership on the project, including significant intellectual contribution, setting up experiments and involvement in making decisions about current and future research directions. You will work in a highly collaborative atmosphere supported by state-of-the-art research facilities that will provide a perfect environment to carry out the project.For informal enquiries, please email Dr Mark Chapman ([email protected]) in the first instance. *Applications will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification. The title of Research Fellow will be applied upon successful completion of the PhD. Prior to the qualification being awarded the title of Senior Research Assistant will be given.Equal Opportunities and Benefits: Biological Sciences holds an Athena SWAN Silver Award, demonstrating commitment to equal opportunities and gender balance in the workplace. We aim to be an equal opportunities employer and welcome applications from all sections of the community. Please note that applications from agencies will not be accepted.The University of Southampton has a generous maternity policy and onsite childcare facilities; employees are able to participate in the childcare vouchers scheme. Other benefits include state-of-the-art on-campus sports, arts and culture facilities, a full programme of events and a range of staff discounts.Please include a covering letter, full CV and names and contact details for three referees in your application.Application Procedure:You should submit your completed online application form at http://www.jobs.soton.ac.uk/www.jobs.soton.ac.uk. The application deadline will be midnight on the closing date stated above. If you need any assistance, please call Sam Stubbs (Recruitment Team) on +44 (0)23 8059 4046. Please quote reference 1064218BJ on all correspondence.