Queen Mary University of London, School of Biological and Chemical Sciences|
Postdoctoral Research Assistant|
A Postdoctoral Research Assistant position is available at Queen Mary University of London (QMUL) as part of a joint project between QMUL, University of Trento, Italy and the University of South California, USA funded by the Human Frontiers Scientific Program. The project ‘Imaging the neurobiology of numerosity- the evolution of counting’ seeks to use zebrafish as a model to unravel the neural basis of non-symbolic number cognition.This particular research position will focus on the characterization of the ontogeny of numerosity discrimination in wild type and mutant zebrafish. You will work together with 2 PhD students and a post-doctoral scientist within the School of Biological and Chemical Sciences at QMUL under the direct supervision of Dr. Caroline Brennan, but will also closely collaborate with the research group of Profs. Giorgio Vallortigara and Scott Fraser at the Mind Brain Institute, Trento, and the Translational Imaging Centre, Los Angeles, respectively. The candidate will be the leading zebrafish neuroscientist on the project and in charge of generation and characterisation of targeted loss-of function mutant lines. You will provide mutant lines with differential behavioural abilities to partners for further behavioural and imaging analysis. The project aims at gaining a better understanding of the evolution and neural basis of human numerosity. The ideal candidate for this position should have a PhD in neuroscience. Experience in the generation of targeted loss-of –function mutants and zebrafish developmental analysis would be desirable. A track record of peer-reviewed publications is essential.This is a full-time, fixed term post available for a period of 3 years. The start date is 1/12/2017. The starting salary is £36,064 per annum and is inclusive of London allowance. Benefits include 30 days annual leave, final salary pension scheme and an interest–free season ticket loan.Candidates must be able to demonstrate their eligibility to work in the UK in accordance with the Immigration, Asylum and Nationality Act 2006. Where required this may include entry clearance or continued leave to remain under the Points Based Immigration Scheme.Informal enquiries for further information are welcomed and may be made to Dr. Caroline Brennan, email: [email protected]
or Tel +44 (0)20 7882 6357For further information about the School, please see http://www.sbcs.qmul.ac.uk. To apply, please visit the Human Resources website on http://www.jobs.qmul.ac.uk and search for reference QMUL11942Application enquiries should be directed to [email protected]
The closing date for applications is 13 August 2017. Interviews will be held shortly thereafter. Valuing Diversity & Committed to Equality
New York University Abu Dhabi, Division of Sciences and Mathematics|
Post-Doctoral Associate, Division of Sciences and Mathematics, NYU Abu Dhabi|
Post-Doctoral Associate Division of Sciences and MathematicsNYU Abu DhabiApplications are invited for a postdoctoral position on Lagrangian numerical methods for studying ocean dynamics with Professor Francesco Paparella at New York University Abu Dhabi (NYUAD). The appointment will be for one year with potential for further two-years renewal, starting no later than Spring 2018. The successful candidate will be in charge of developing a Lagrangian numerical code running as a subsystem of an ocean circulation model (ROMS will be the initial testbed). The code will differ from current Lagrangian codes in being focused on on-line (that is, running synchronously with the circulation model) calculations with a number of particles comparable with the number of Eulerian grid nodes. The focus will initially be on elucidating the advantages of on-line vs off-line calculations. In the long run the goal is to use it as the foundation for innovative biogeochemical modelling. The post-doc will have direct access to NYUAD’s high performance computing facility (the Dalma cluster), and will be working in close contact with post-doc and researchers of the Center for Prototype Climate Modeling (http://nyuad.nyu.edu/en/research/nyuad-institute/institute-research/cpcm.html), joining a small team of scientists engaged in a broad effort to develop Lagrangian models to understand and model Ocean and Atmospheric dynamics. Funds will be available for travel to conferences and for other collaborative endeavors. Applicants must hold a PhD in ocean/atmospheric sciences, applied mathematics or related fields. The successful applicant will have significant experience in developing numerical codes in Fortran or C, in addition to running parallel code on high performance computing facilities and analyzing its outputs. Familiarity with ocean or atmospheric circulation models, and in particular with ROMS will be a plus. The terms of employment are very competitive. Applications will be accepted immediately and candidates will be considered until the position is filled. To be considered, all applicants must submit a cover letter, curriculum vitae, transcript of degree, a one-page summary of research accomplishments and interests, and at least 2 letters of recommendation, all in PDF format. Please visit our website at http://nyuad.nyu.edu/en/about/careers/faculty-positions.html for instructions and information on how to apply. If you have any questions, please email [email protected]
About NYUAD: New York University has established itself as a Global Network University. The network has three foundational degree-granting campuses: New York, Abu Dhabi, and Shanghai, complemented by a network of eleven research and study-away sites across five continents. Our students are drawn from around the world and surpass all traditional recruitment benchmarks, both US and global. Our goal is to develop a cohort of international students attuned to and educated for an inclusive global society. Students and Faculty will circulate within the global network in pursuit of common research interests and the promotion of cross-cultural and interdisciplinary solutions for problems both local and global.Entering its eighth year, NYU Abu Dhabi has recruited a cohort of faculty who are distinguished in their research and teaching. NYU Abu Dhabi’s highly selective liberal arts enterprise is complemented by an institute for advanced research, sponsoring cutting-edge projects across the Arts, Humanities, Social Sciences, Sciences, and Engineering. EOE/AA/Minorities/Females/Vet/Disabled/Sexual Orientation/Gender Identity Employer
Medical Research Council, Laboratory of Molecular Biology, LMB|
Postdoctoral Scientist – Computational Genomics|
Postdoctoral Scientist – Computational GenomicsStarting Salary £30,162 to £32,975 per annumMRC Laboratory of Molecular Biology, Cambridge UK We are looking for somebody to join the group of Prof Julian Gough to work on big data, data science, algorithms, data integration, machine learning and statistical methods applied to protein structure domains (SUPERFAMILY), protein disorder (D2P2), protein function and phenotype (dcGO) and other areas such as genetic variation (FATHMM). This project is to bring together our previous research in these areas with diverse and large biological datasets and to unite it into a coherent system for conducting cutting edge genomic research.The explosive amount of biological data coming from advances in high-throughput techniques such as DNA sequencing constitutes one of the two most important areas of data science for the next half-century (the other being internet-related). Unlike the more obvious internet-related areas of big data research, there is a lack of highly skilled and motivated computer scientists to work on the important problems. This opportunity to work in the Gough group is a chance to become one of those people.You are highly motivated, have a PhD in a relevant subject, and you have an aptitude for computer science, mathematics and working with data. This role will suit you if you enjoy learning and are comfortable working in an application area that stretches your comfort zone.The successful applicant(s) will be awarded a 3 year Career Development Fellowship/MRC Postdoctoral Training Scheme. Working for the MRC provides a whole host of benefits including a final salary pension scheme, Benenden Healthcare membership and excellent holiday entitlement. You will also have access to employee shopping/travel discounts, on site sport and social facilities, as well as salary sacrifice cycle to work schemes and childcare vouchers.The MRC Laboratory of Molecular Biology is one of the birthplaces of molecular biology and is an internationally renowned centre for fundamental biomedical research, with well-recognised fundamental contributions to computational biology and bioinformatics.The LMB has a strong track record in training Postdoctoral Fellows who have gone on to become leading Scientists. We also have an excellent record of innovative basic research leading to translation and commercialisation. Scientists are drawn to the LMB from all over the world, thus creating a lively and international community for the exchange of ideas and technical innovation. For further information of the research undertaken at the LMB, please visit:http://www2.mrc-lmb.cam.ac.uk To apply and access full details of the vacancy please visit our job board at https://mrc.tal.net/vx/lang-en-GB/appcentre-1/candidate/postings/644.If you are unable to apply online please contact us at [email protected]
date: 2nd August 2017Final appointments will be subject to a pre-employment screening.The Medical Research Council is an Equal Opportunities Employer who participates in the Disability Confident scheme
RM IT Professional Resources AG|
Ruby on Rails Engineer (Senior)|
Ruby on Rails Engineer (Senior) knowledge wanted for our Berlin based client in the IT sector.Your experience/skills:Degree in Computer Science, Software Engineering or in a related field, Masters' Degree or PhD is preferred3+ years' experience working as a Ruby on Rails Engineer or in a similar position with extraordinary Full Stack Engineering expertisePractical knowledge in relational database systems, like PostgreSQL or MySQL, as well as familiarity with AWS (EC2, S3, RDS) and HerokuLanguages: fluent English both written and spoken, knowledge in German is an assetYour tasks:Building API and tools for scaling up and supporting applications with millions of usersAssisting on drive core technical decisions as well as integrating 3rd party servicesWorking on a large project with Ruby on RailsCommitting code, writing tests and solving problemsStart: ASAP Duration: Permanent Location: Berlin, Germany Ref.Nr.: BH11214Does this sound like an interesting and challenging opportunity to you? Then take the next step by sending us your CV as a Word document and a contact telephone number.Due to work permit restrictions we can unfortunately only consider applications from EU or Swiss citizens as well as current work-permit holders for Switzerland.Going the extra mile New to Switzerland? In case of successful placement, we support you with:All administrative questionsFinding an apartmentHealth - and social insuranceWork permit and much more
The Job Jobber|
Principal Engineer - Biologics Process Development|
Salary: $120,000 - $145,000Company is seeking a Principal Engineer to lead projects in the Biologics process development and clinical manufacturing projects. The individual will design, develop, scale-up and optimize drug substance and drug product unit operations for protein therapeutics. Experience managing projects from Discovery integration through GMP manufacturing, with both internal and external partners are required. The candidate should have strong technical, communication and interpersonal skills, be able to multi-task, and to work across diverse, cross-functional teams both onsite and across sites.The key duties of this role are to provide technical leadership in biologic/protein therapeutic process development and early stage clinical manufacturing (Phase I/II). The role will also be responsible for leading tech transfer of drug substance and drug product processes to CMOs for Phase III and Commercial operations. Extensive experience in upstream process development and early phase clinical manufacturing required. Demonstrated ability to develop, optimize and scale up robust bioreactor processes using statistical experimentation and QbD principles is essential. Additionally, knowledge of chromatography, lyophilization, filtration and viral reduction downstream process steps is highly desirable. Mentoring junior level Scientists and Research Associates is also essential. QUALIFICATIONS Extensive experience in statistical design of experiments and QbD principles Process development in upstream (bioreactor) Process definition through optimization Strong problem solving skills Experience in developing process risk assessments Clinical manufacturing to commercial manufacturing of DS Sound working knowledge of current regulatory requirements Experience with process validation Experience with commercial manufacturing DP manufacturing experience helpful Strong writing skills required for process documentation, technical reports and regulatory filings Build strong relationships with internal and external stakeholders to advance program goalsEDUCATION AND EXPERIENCEMS or PhD in Chemical or BioengineeringMS with 12-15 years bioprocessing experience in mammalian cell culturePh.D. with 8-10 years bioprocessing experience in mammalian cell culture
Technical Author - Graduate PhD/MSc/BSc in Computer Science, IT Techni|
Technical Author - Graduate (PhD/MSc/BSc in Computer Science, IT, Technical Communications or similar) Our award-winning, enterprise-level software client is looking for an enthusiastic and motivated graduate to join their small but thriving documentation team. With full support and training you will produce a range of technical documentation, primarily for a software developer audience. You'll help to create high quality product documentation, describing complex software architectures and how to develop software applications using the SDK, APIs, and developer tools. Our client welcomes applications from graduates and juniors who want to kickstart an exciting new career in technical communications. As the successful candidate, you will have: A degree in IT, Computer Science, Technical Communications, or any other applicable technical discipline with an interest in technical writing. A technical background with the ability and enthusiasm to grasp enterprise -level technology. Excellent written and verbal communication skills, with the ability to understand technical concepts and explain them in simple, clear and concise terms. A real appetite and enthusiasm for new technology and developing new skills. A can do approach to a wide and rapidly changing workload. This is a great opportunity to join a friendly, professional writing team within a dynamic software company. A stimulating and rewarding working environment is on offer, as is a very competitive remuneration and benefits package. The office is in a central location within easy walking distance of a mainline train station.
Principal Data Scientist Machine Learning|
Data Science - Machine Learning - Algorithms - Python - Boston - Healthcare Our Client, a market leading healthcare organization, are seeking highly skilled Principal Data Scientist for their team in Boston. This role provides the opportunity to implement cutting edge machine learning models and algorithms to deliver actionable intelligence from large sets of structured and unstructured data.The vision of this business is to help to provide improved access to quality health care services for people throughout America, by working with doctors, hospitals and health networks alike.Skill requirements: 8+ years of experience in Data Science and Machine LearningPhD in relatable field (statistics, computer science, analytics, or other quantitative discipline)Machine learning: clustering, decision trees, neural networks and affinity analysisRelatable industry experience is a plusProven expertise in the fundamentals of statistical (Machine Learning, NLP)Role responsibilities:Lead development and execute new and highly complex algorithms and statistical modelsDetermine analytical and modelling techniques to evaluate potential future outcomesDevelop creative and intelligent Machine Learning modelsApply cutting edge machine learning theories and techniques to investigate problems, detecting patterns and recommending solutionsProvide guidance and develop strategy for business wide analytics roadmaps.Data Science - Machine Learning - Algorithms - Python - Boston - Healthcare This in an urgent requirement for an exciting business that is experiencing exponential growth, so if you have a passion for Data Science/Machine Learning and want to apply this to an industry that can change people's lives, then get in touch!
ICR, The Institute of Cancer Research, Division of Cancer Biology|
Postdoctoral Training Fellow|
A Postdoctoral Training Fellow position is available immediately to join the laboratory of Dr George Poulogiannis based in the Division of Cancer Biology at the Institute of Cancer Research. His team is also a member of the ICR-Imperial Centre for Systems Oncology and Cancer Innovation. We seek to appoint a highly motivated and creative individual with a strong interest in cancer biology to carry out research on understanding the therapy sensitivity pattern of metabolically-distinct breast cancer phenotypes using genetic and pharmacological approaches across patient-derived xenograft (PDX) and organoid (PDO) models.This is an ideal opportunity for a committed and enthusiastic scientist to join a dynamic research team with excellent collaborators and facilities. For more information about our research, please visit: http://www.icr.ac.uk/our-research/researchers-and-teams/dr-george-poulogiannis. The project is part of the CRUK Grant Challenge Award funded program that aims to map the entire molecular make-up of tumours using the latest technologies in high-throughput mass spectrometry imaging. For more information please visit: http://www.cancerresearchuk.org/funding-for-researchers/how-we-deliver-research/grand-challenge-award/funded-teams-bunchYou should hold a PhD (or equivalent) in Cancer Biology, Biochemistry or other similar disciplines and have experience with the following techniques: generation and passaging of breast cancer patient derived xenograft (PDX) and organoid (PDO) models, functional genomics via next generation sequencing, 3D cell culture and genome editing.Appointment will be on Fixed Term Contract for 3 years. The full salary scale for the post is in the range of £29,960 to £42,820 p.a. inclusive. Starting salary will be based on postdoctoral experience. Informal enquiries are welcome and can be made to Dr. George Poulogiannis ([email protected]
). Please note, this address is for enquiries only and you should not send your application to this email address. To apply please submit your CV and covering letter (addressing with specific examples where you meet the person specification and incl. the names and addresses of two referees) online. Job Ref. No. 71
University of Nottingham, Engineering|
Research Associate/Fellow in Robotic Control (fixed term)|
Applications are invited for the above two year fixed-term position at the Rolls-Royce Manufacturing and On-Wing University Technology Centre (see: http://www.nottingham.ac.uk/utc) within the Faculty of Engineering. The Faculty has an excellent international reputation for high quality theoretical and experimental research funded by EPSRC, Innovate UK, EU and manufacturing industry.The Rolls-Royce Manufacturing and On-Wing University Technology Centre (UTC) at the University of Nottingham is looking to recruit a researcher in robotic control to contribute to existing projects and conduct research within the expanding research groups. This is an exciting opportunity for an experienced graduate/postgraduate to play a leading role in challenging projects. In particular, to coordinate and carry out theoretical and experimental work for developing control methods and architectures for robotised machine tool systems and supervised processes.Candidates must possess a good knowledge of theoretical models and control algorithms, kinematic analysis, robotic hardware and actuation solutions and demostrate strong evidence of developing their own software/fireware to control such robotic systems. Previous expertise in developing customised robotic systems (e.g. for manipulation/surveillance) would be preferable.Apart from being capable to lead the research work on different projects, good communication, presentation/reporting and publishing skills are required for the person appointed to effectively interact with the international academic and industrial partners collaborating with the centre. In addition to carrying out projects' work, the researcher will benefit from exposure to internationally leading industrial companies that are interested in the results of the projects and willing to collaborate on spin-out individual projects. Candidates must possess a good first degree in mechatronics/mechanical engineering or related disciplines, and preferably a PhD degree in mechatronics/robotics or be close to completion.This full-time post will be offered on a fixed-term contract for a period of 2 years.To apply, please follow the link: http://www.nottingham.ac.uk/jobs/currentvacancies/ref/ENG237817Informal enquiries may be addressed to Prof. D Axinte, tel: 0155 9514117 or email [email protected]
note that applications sent directly to this email address will not be accepted.The University of Nottingham is an equal opportunities employer and welcomes applications from all sections of the community.
Key Retirement Group|
Following the investment in a data warehouse we have an overwhelming desire to become data-driven and insight led. If you didn't know, we are the KR Group, an award-winning, entrepreneurial financial services group for those both in, and approaching, their retirement. Our market share is already 35% and rising, so the future of our business looks very bright indeed. You will be excited by learning about our business which we understand is probably not overly familiar to most people. Over time, you will become an expert and someone our colleagues and senior decision makers turn to for analytical support. You will shape and deliver proactive insightful analysis across our business and present findings to our leadership team, in the form of reports, data visualisation and data-stories. You adore all things to do with BI, Insight and Statistics. You have experience providing actionable commercial insight solutions to a business which sometimes works at a pace of delivery that is demanding. You might have a degree, Masters or PhD in Maths, Business Systems/BI or Computer Science or are qualified by experience. We would love to hear from you if you have experience of any or all of the following: SPSS, SAS, SSAS, R/Python, MS SQL programming and the use of geographical analytical tools would be a bonus. This role will take hard work, commitment and self-motivation but in exchange it will also enhance your career working alongside a talented team and a head of department, who are leaders in their field. To apply for this position please click the APPLY button!
SJB Technical Recruitment Ltd|
Biomaterial Research Scientist (ISO13485, New Product Development, Mou|
Biomaterial Research Scientist (ISO13485, New Product Development, Mouldings) South Oxfordshire £33k - £40k plus benefits Our client is a fast-growing medical implant company, involved in developing a fantastic new product, a natural regenerative orthopaedic implant, using a protein biomaterial with a molecular structure that emulates the human body and repairs and regenerates damage. The Biomaterial Research Scientist is a broad ranging laboratory and office based role with responsibility for Product development through preclinical, and clinical phases Leading R&D function activities on development projects Developing and implementing research plans Problem solving Interfacing with both internal and external research teams to develop and analyze prototypes, Furthering the development of core technologies Identifying and implement new technologies to enable GMP manufacturing of novel implantable devices. Experience and Qualifications A relevant Degree or equivalent qualifications (Essential). An MSc/MPhil/PhD in related field (Desirable). 3-10 years of experience of development within chemistry/biochemistry/biomaterials/textiles, ideally materials or protein chemistry, solving technical problems to achieve project objectives. Experience of product development in an ISO13485 or QSR820 environment (Essential). Novel implantable medical devices experience (advantageous). A practical approach and enjoy hands on' experimental work. Confidence when working independently, but able to work well within a team.
Divisions of Structural Biology and Cancer Biology, ICR, The Institute of Cancer Research|
Postdoctoral Training Fellow: Protein Biochemistry / Cryo-Electron Microscopy|
We seek to appoint a Postdoctoral Training Fellow to the research team led by Dr Sebastian Guettler in the Divisions of Structural and Cancer Biology. Work in the Guettler laboratory centres on the elucidation of signal transduction mechanisms relevant to the function of cancer cells, in particular the Wnt/-catenin network and telomere homeostasis and their control by poly (ADP-ribosyl)ation. We take a multi-disciplinary approach that combines structural biology, both by X-ray crystallography and cryo-electron microscopy, biochemistry, biophysics and functional studies in mammalian cells. For a recent publication, please see Mariotti et al. (2016). Molecular Cell 63, 498–513. Additional information is available at http://www.icr.ac.uk/our-research/researchers-and-teams/sebastian-guettler.You will undertake biochemical, structural and functional studies on macromolecular complexes controlling the maintenance and integrity of telomeres, and their regulation by poly(ADP-ribosyl)ation. A central component of the research project will be the structural analysis of large multi-protein assemblies by cryo-electron microscopy.You should possess a PhD in a biological science such as biochemistry or molecular biology and have experience with single-particle electron microscopy. In addition, experience with recombinant DNA techniques, high-quality protein expression and purification, protein characterisation, such as protein-protein interaction analyses, is essential. Experience in protein production in insect cells would be advantageous.Appointment will be on a Fixed Term Contract for 3 years. The full salary scale is in the range from £29,960 - £42,820 p.a. inclusive. Starting salary will be based on postdoctoral experience. To apply, please click below to submit your CV and covering letter online. In your covering letter, please address with specific examples where you meet the person specification and summarise your research interests and motivation for applying. Please include the names and addresses of two referees.Job Ref. No.: 90Closing date: 18th August 2017Informal enquiries can be made to [email protected]
Please do not submit your formal application by email; applications must be submitted in line with the instructions above.Research in the Divisions of Structural Biology and Cancer Biology focuses on the functional, biochemical, and structural characterisation of cellular processes relevant to cancer and cancer therapy. The Division of Structural Biology has managed facilities for protein production, with expertise in multi-subunit expression (insect cell, yeast and bacterial expression, including a 60-litre fermentor), protein crystallography (crystallisation robots, Bruker Microstar and CCD detector) and cryo-electron microscopy (FEI Tecnai F20 and T12). Regular access to shared cryo-electron microscopy facilities, such as eBIC, is available. Moreover, the Institute of Cancer Research will be part of the London Consortium for Cryo-Electron Microscopy, hosting an FEI Titan Krios cryo-electron microscope equipped with a Volta phase plate, a Falcon III detector and a Gatan Bioquantum energy filter and K3 detector. The Division is also well-equipped with instrumentation for biophysical analysis (e.g. ITC, fluorescence, multi-angle light scattering).The Division of Cancer Biology provides a state-of-the-art infrastructure for mammalian cell culture, light microscopy, mammalian genetics, chemical biology and proteomics.The Institute of Cancer Research, London, is one of the world’s most influential cancer research institutes. We provided the first convincing evidence that DNA damage is the basic cause of cancer, and today lead the world at isolating cancer-related genes and discovering new targeted drugs for personalised cancer treatment.The Institute of Cancer Research (ICR) came top in the league table of university research quality compiled from the Research Excellence Framework (REF 2014). Based on our publication record, citations and impact, we rank among the world’s leading cancer research centres. As a college of the University of London, the ICR provides postgraduate higher education of international distinction. We also have charitable status and rely on support from partner organisations, charities, donors and the public. The ICR is committed to attracting, developing and retaining the best minds in the world to join us in our mission – to make the discoveries that defeat cancer
University of Southampton, Southampton General Hospital|
Research Fellow in Clinical Neurosciences|
Location: Southampton General HospitalSalary: £29,301 per annumFull Time - Fixed Term for 3 yearsClosing Date: Friday 18 August 2017Reference: 896717FCApplications are invited for a Research Fellow to join Dr Ratnayaka’s group to study the effects of Retinal Pigment Epithelial (RPE) pathology leading to Sorsbys Fundus Dystrophy (SFD); an autosomal dominant macular dystrophy with no effective treatment.You will have a PhD* or equivalent professional qualifications and laboratory experience in areas of cell biology and/or retinal biology. Previous experience in cellular/in-vitro disease modelling, molecular biology and extracellular matrix (ECM) modulation would be an advantage. Prior experience in RPE biology and/or generating adult induced pluripotent stem cells (iPSC) would also be advantageous. Candidates should be capable of independently designing and carrying out experiments as well as intellectually contributing to the project to achieve its goals in a timely manner. Evidence of publishing in high-quality, peer-reviewed journals would be desirable.The Ratnayaka group investigates degenerative mechanisms in the senescent retina and brain. This project, funded by RP Fighting Blindness, will provide an opportunity to elucidate mechanistic changes in the RPE monolayer in relation to its underlying substrate. Potential findings may not only reveal new insights into dynamic RPE-ECM interactions underpinning SFD, but other retinopathies such as AMD. The project will employ techniques including cell culture-disease modelling, molecular biology/biochemistry, CRISPR/Cas9 gene-editing, confocal and ultrastructural imaging as well as working with iPSC-RPE. Hence this exciting project offers the opportunity to work at the interphase of cutting-edge, multidisciplinary research.You will join a vibrant and dynamic research group and be expected to work as a team with other postdocs, PhD/undergraduate students and technicians. You will collaborate with colleagues across Faculties of Medicine and Biological Sciences at the University of Southampton. The successful candidate may be offered an honorary NHS contract for accessing patient samples and data relevant to the project. The candidate can expect a collegial and research-focused environment with mentoring and career development support from the PI. The post is available for a period of 3 years. Due to funding requirements the post can only be offered on a full-time basis.Interviews for shortlisted candidates are likely to be held in September 2017.Informal inquires may be directed to Dr Ratnayaka ([email protected]
).Application Procedure:You should submit your completed online application form at www.jobs.soton.ac.ukThe application deadline will be midnight on the closing date stated above. If you need any assistance, please call Geraldine Lewis (Recruitment Team) on +44 (0) 23 8059 2507. Please quote reference 896717FC on all correspondence.Applications for Research Fellow positions will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification. The title of Research Fellow will be applied upon successful completion of the PhD. Prior to the qualification being awarded the title of Senior Research Assistant will be given.The Faculty of Medicine holds an Athena SWAN Silver Award demonstrating commitment to equal opportunities and gender balance in the workplace. The Faculty recognises that applicants may seek flexible working patterns which will be considered as part of the recruitment process. For further information including key benefits designed to help maintain and support employees' well-being and work-life balance, please see our working with us website pages.
UNESP - Sao Paulo State University, Department of Morphology/Institute of Biosciences|
Bioinformatics applied to chromosome biology|
Postdoctoral Position – Bioinformatics in Animal CytogenomicsThe Integrative Genomics Laboratory, hosted by São Paulo State University, Brazil, and funded by FAPESP (São Paulo Research Foundation) is offering a postdoctoral fellowship for PhDs with outstanding research potential Project Title: Towards a functional view of B chromosome biology and its interface with sex chromosomes.Starting date: February 1st, 2018Application Deadline: August 30th 2017Duration: 24 months that can last up to 48 monthsInstitution: The fellowship holder will work in the Integrative Genomics Laboratory (www.ibb.unesp.br/lgi), Institute of Biosciences, São Paulo State University (Unesp), Botucatu, SP, Brazil. Address: Rua Prof Zanin, 250. 18618-689. Botucatu, SP, Brazil.Funding agency: São Paulo State Research Foundation – FAPESP.Benefits:Fellowship: monthly stipend of R$6,819.30; R$ 81,831.60/year (~US$ 24,800.00/year);Travel/Moving support: one additional monthly stipend (paid with the 1st fellowship payment) and flight tickets to support moving to Botucatu, SP, Brazil;Research Contingency Funds: 15 per cent of the annual value of the fellowship for use in activities developed by the fellowship holder, strictly related to the fellowship research project;For details on the fellowship and candidate obligations, check http://www.fapesp.br/en/postdocJob DescriptionThis project is part of a major project involving structural and functional genomics, cytogenetics, bioinformatics and systems biology applied to the study of sex and B chromosomes in different animal models (fishes and insects). The general aim is to advance in the knowledge of the molecular basis that governs the evolutionary history of these chromosomes.General Tasks: Genome assembling and annotation, search of B and sex chromosomes sequences, genome rearrangements, transcriptomes and microRNomes analysis, gene enrichment analysis, proteomes, and protein networks construction.Essential skills and experiencePhD in one of following areas: genetics, molecular biology, biochemistry, bioinformatics or equivalent fields;Experience with bioinformatics applied to genome assembling, genome annotation and transcriptome analysis (mapping/assembling, annotation, differential expression analysis, gene ontology and metabolic pathways descriptions);Experience with bioinformatics applied in proteomics (mass spectrometry) (desirable, but not required);Proficiently in written and spoken English.Programing in Python, or Pearl or C++ (mandatory);Graphical data analysis with R, Python, Wolfram, or similar;General statistics or math (desirable but not required);Leadership and group work;Scientific criticism;Open minded, creative and cooperative.We offerA working team where trust, international collaboration, and commitment are essential;Access to state-of-the-art tools and infrastructure;A stimulating and supportive research environment.How to applyIn order for your application to be processed, the following documents must be submitted by e-mail to Dr. Cesar Martins ([email protected]
).1) Curriculum;2) Motivation letter outlining details of research interests, expertise, availability, and any further information relevant to the application 3) Two reference letters (e-mails accepted) from previous professors/advisors/co-workers;4) Copy of PhD degree certificate.All documents must be presented in English or Portuguese.For further information please contact Dr. Cesar Martins [email protected]
Clearwater People Solutions|
Principle Medical Writer|
OVERVIEWCurrently recruiting for a Principal Medical Writer for a specialist healthcare communications agency, located in Lancashire. Within this position, the responsibilities will include producing high-level medical writing to support across a variety of accounts. Striving to achieve writing excellence across therapy areas and the communication mix. This position reports to the Scientific Director and is responsible for Associate Medical Writers and Medical Writers.KEY RESPONSIBILITIES - Keeping up to date with codes of practice and legislation - Work across several accounts and support Junior Writers - Promotion of quality control processes and procedures - Work across multiple therapeutic areas - Develop in-depth understanding of client and competitor products, therapy areas and portfolio - Technical Lead on designated client projects - Ensure departmental objectives are achieved - Relationship building with internal and external stakeholders - Identify opportunities to maximise business from accounts - Exemplify the organisations values and behaviours - People ManagementKEY SKILLS - MD, Pharmacist or PHD - Substantial experience of working in medical communications - Demonstrable experience working working as a Medical Writer, ideally within an agency environment - Recognise the focus on the customer - Proficient in standard software; Word, Excel, PowerPoint and OutlookWhat is Offered: - Full-time career opportunity with career progression - Market-leading salary will be offered depending on level of experience and skills - Permanent contract of employment with company perks and benefitsWhy this Vacancy is right for you: - Established and successful company. - Investment in employee development.Please send your application* with your most recent CV today via Pharmiweb. To find out more about this career opportunity please call Sarah or email (see below) detailing your interest. If this role is not right for you, please contact us to discuss what you are looking for.*Applicants who have not had a response within two weeks should assume their application has been unsuccessful.Clearwater People Solutions are proud to offer a service based on a quality and personalised approach. We work diligently on behalf of our Candidates to find the right role that you and your specialist skill set deserve. Our consultative, honest approach combined with our integrity and full qualification of each-and-every requirement we work make us a perfect partner for you in your search for the ideal position. At Clearwater: your Career is our Job. We look forward to hearing from you.Medical Writer/Medical information/Pharmaceutical/Medical/Surrey/Kingston/Surbiton/Copy Approval/Life Science
Technische Informationsbibliothek (TIB)|
Research group leaders Web&Data Science|
Acting in the capacity of the German national library of science and technology, our forward-looking services secure the infrastructural requirements for providing researchers in science and industry with highquality information and literature. The services we offer in our capacity as a University Library ensure that Leibniz Universität Hannover is provided with items locally. The Technische Informationsbibliothek (TIB) - German National Library of Science and Technology, Programme Area C, Research and Development, is looking to employ Research group leaders Web&Data Science (E 14 TV-L) The ideal candidate holds a doctoral degree in Computer Science, Information Science, Mathematics or a related field and is able to combine theoretical and practical aspects in her/his work. The candidate is expected to build up her/his own research group and should have a track record in at least three (and be committed to expand to more) of the following areas: Publication of research results in renowned, peer-reviewed journals and conferences of her/his field Proven software engineering skills and the ability to develop mature software components beyond pure research prototypes Successful supervision of bachelor, master and doctoral students Collaboration with other research groups, industry, NGOs as well as open-source and community initiatives, for example, in the context of publicly funded collaborative research projects Successfully competing for funding by national and international funding bodies Transfer and commercialization of research results, for example, through open-source software or contractual research and development for public institutions, industry or other stakeholders Due to the embedding of the group at Leibniz University Hannover, Leibniz Information Center for Science&Technology (TIB) and L3S Research Center (L3S) particular emphasis will be on the successful transfer of research results into sustainable technologies, software components and services facilitating high-impact information services as well as societal and industrial applications. Fluent English communication skills are a fundamental requirement; command of German language is a plus. Fields: The candidate should have a background in a field relevant for Web and Data Science such as: Semantic technologies, linked data, knowledge graphs and ontology engineering Artificial intelligence, knowledge representation and machine learning Natural language processing and information retrieval Software engineering and modern application development Data management, integration and analysis Human-computer interaction and data visualization Applications: The candidate should be interested to pursue applications of her/his research in areas including (but not limited to): digital libraries, data integration for science and technology, question answering, scholarly communication, e-learning, open science&crowdsourcing. What we offer: We provide a scientifically and intellectually inspiring environment with an entrepreneurial mindset embedded in a leading technical university and one of the largest technical information centers being part of Leibniz research association. Our aim is to provide the environment and resources to make the research group leaders successful in their field. Research group leaders will have initially one or two PhD student positions assigned. There is funding available for equipment, conference and research visit travel and all costs required for a successful built-up of the research group. Possibility to pursue further academic qualifications such as habilitation and teaching experience A portfolio of technology components to build on, including DBpedia, BigDataEurope platform, OntoWiki, Qanary QA, SlideWiki etc. TIB/L3S are already engaged in a number of research projects at the national and European level The positions start as soon as possible, are open until filled and will be granted initially for 3 years with envisioned extension for another 3 years and an option to make the position permanent thereafter. How to apply: Please send your CV, two publications, 1-2 letters of reference and a two-page motivational statement (incl. research, funding and transfer ambitions) to Technische Informationsbibliothek (TIB) Personalservice Herrn Daniel Eilers Welfengarten 1 B 30167 Hannover Germany You can also send your application by email: Please do not send emails larger than 10 MB. Questions regarding the positions can be addressed to the designated new director of TIB, Prof. Dr. Sören Auer ( ). For more information about the TIB, please visit: TIB provides ideal working conditions, and continuously takes action to enable its employees to combine career interests with family life. Severely disabled candidates with comparable qualifications will be given preferential treatment. We look forward to receiving your application. Please note that your application documents will not be returned. Application and travel costs cannot be reimbursed.
Cranfield University, School of Water, Energy and Environment|
Research Fellow in Climate Change Adaptation|
Here at Cranfield, we can offer you the opportunity and resources to really develop your career. Cranfield is an exclusively postgraduate university that is a global leader for education and transformational research in technology and management.The Water theme has an international reputation for its transformational research and teaching in the science, engineering and management of water in the municipal, industrial and natural environments. Our activities deliver pioneering research that has changed water management thinking and practice and provide progressive educational and research support for practitioners, often through ground breaking collaborations with the private sector. These contributions are founded on strong scientific foundations and are drawn from right across the science and humanities spectrum.You will support the Institute’s contribution to “Impacts and risks from high-end scenarios: Strategies for innovative solutions (IMPRESSIONS)”, a project funded by the European Commission’s Seventh Framework Programme. IMPRESSIONS aims to advance understanding of the implications of high-end climate and socio-economic change, involving temperature increases above 2°C, and to help decision-makers apply such knowledge within integrated adaptation and mitigation strategies. You will model and analyse multi- and inter-sectoral adaptation pathways in Europe, covering urban, agricultural, forestry, water resources, flooding and biodiversity sectors and to contribute to the cross-sectoral and cross-scale synthesis activities of IMPRESSIONS. You will also support the delivery of other research contracts for clients on a range of water resource management issues including water security, catchment processes, and agricultural water use.You will have a PhD obtained (or be close to completion) in Environmental Science or a related discipline, strong data analysis, experience of applying a range of modelling techniques or disciplines to environmental problems, a growing publication track record and well-developed written and oral communication skills.For an informal discussion, please contact Prof Ian Holman, Professor of Integrated Land and Water Management, on +44 (0)1234 758277 or (E); [email protected]
Cranfield University is committed to promoting a harmonious working and learning environment where everyone is treated with respect and dignity, recognising that the contribution of all its people will be most effective in conditions which are inclusive.We are signatories to the Athena SWAN Charter and achieved a Bronze Opportunity Now Award. We also run the Leadership Foundation’s Aurora Programme, which is a leadership development programme, aimed at women in an academic, technical or professional service role. Your career at Cranfield will be enhanced through access to fully equipped shared laboratory and pilot facilities, extensive research and business training through our learning and development team and doctoral training centres in a collegiate and supportive environment.Apply online now at www.cranfield.ac.uk/hr or contact us for further details on E: [email protected]
or T: +44 (0)1234 750111 Ext. 4951. For any enquiries, please quote reference number 2506. Closing date for receipt of applications: 03 August 2017Interviews to be held: 10 August 2017www.cranfield.ac.uk
University of Kansas, Department of Ecology and Evolutionary Biology|
Postdoctoral researcher in population modelling|
Dr Daniel Reuman is recruiting into his lab in the University of Kansas Department of Ecology and Evolutionary Biology (EEB). At least 3 years of funding are available to carry out modelling pertaining to spatial population dynamics and analysis of large spatial population data sets. The postdoc will join an interdisciplinary team consisting of Reuman, three postdocs and one student currently in the Reuman lab, collaborators in EEB and in the Math Department at KU, and collaborators at several institutions in the USA and UK. Funding is from the NSF Mathematical Biology program and the James S McDonnell Foundation. In many hierarchical dynamical systems, “synchrony” between multiple fluctuating variables, i.e. correlations or other similarities in fluctuations between variables through time, is more important than the individual variables themselves. For instance, a neuron may fire only when its input neurons fire synchronously. Or the electrical grid may crash only when demands of multiple users become synchronized, producing total-usage spikes. Ecosystems can show this type of dependency on synchrony. Ecosystems include multiple trophic levels, with population signals from lower levels often being spatially aggregated to affect higher levels. For instance, a predator is only harmed if its prey are scarce over its whole hunting area. For systems of this type, it is primarily the synchronous components of signals that matter in the average signal that affects the next level – non-synchronous components tend to cancel in the spatial average. Thus synchrony is very important to ecosystems. Synchrony is found in organisms as diverse as mammals and protists, at distances up to thousands of kilometers. Synchrony relates to large-scale outbreaks and shortages and is important in conservation. In spite of the importance of synchrony in ecology, possible impacts of climate change on synchrony are little studied. Synchrony can also be transmitted through trophic interactions - e.g., a synchronized predator can induce synchrony in its prey. But the extent to which climate-induced changes in synchrony may cascade through species interaction networks via this mechanism, or influence spatial or other branches of ecology, is unknown. The postdoc will perform statistical and/or mathematical population modelling to address these questions, and will investigate connections to extinction risk models and to Taylor’s law, a commonly applied empirical regularity in spatial ecology. The postdoc will be encouraged to develop his/her own projects within the goals of the funding grants.We seek individuals from biological or physical-science backgrounds with skills and demonstrable interests in modelling and related areas. Experience with stochastic process modelling and Fourier or wavelet approaches is a plus. Experience with population models is a plus, as are computational skills, particularly if applied in a statistical or modelling context. A PhD or ABD in a related field is required. Applicants from underrepresented groups are encouraged. The University of Kansas (KU) is a major research university with special strength in ecology and evolutionary biology. The EEB department has >40 permanent faculty working in a wide variety of theoretical and empirical areas, with National Research Council and Chronicle of Higher Education rankings in the top 10 in the USA. KU is located in Lawrence, Kansas, about 30 miles from Kansas City. Lawrence is a progressive and cosmopolitan university town with vibrant art, music, and sports scenes that has been ranked among the top ten college towns in the country for liveability.See http://www.reumanlab.res.ku.edu/ for further information about the Reuman lab and links to past publications. Email [email protected]
or call 785 864 1542 with questions. A start date during or before autumn 2017 is preferred. To apply, please send a CV, a cover letter of up to two pages, the names and contact information of two references, and one publication to [email protected]
Review of applications has begun. Position open until filled.
Agri Food and Biosciences Institute Northern Ireland AFBI|
PRINCIPAL SCIENTIFIC OFFICER - PATHOGEN GENOMICS BIOINFORMATICIAN|
PRINCIPAL SCIENTIFIC OFFICER - PATHOGEN GENOMICS BIOINFORMATICIAN REF: IRC220207SALARY: £47,749 - £52,334DEPARTMENT: Agri-Food and Biosciences Institute Northern Ireland (AFBI)LOCATION: AFBI Stormont, BelfastThis new post offers an exciting opportunity for a skilled and experienced Pathogen Genome Bioinformatician to join AFBI at a pivotal time to enable AFBI to harness the potential of genomics across the diverse data streams and remits of AFBI and to establish a new cross-cutting pathogen genomics and bioinformatics platform to drive the development of AFBI in forthcoming years. The successful candidate will lead and manage this high-priority area within a well-established and multi-disciplinary scientific group, providing considerable impacts for the agri-food industry and tangible achievements both within and beyond academia.Further appointments may be made from this competition should AFBI positions become vacant which have similar duties and responsibilities.For more detailed information and to apply, please go to www.nicsrecruitment.org.ukAlternatively, an application pack can be requested by contacting:HRConnect, PO Box 1089, The Metro Building, 6-9 Donegall Square South, Belfast, BT1 9EW. Telephone: 0800 1 300 330. Email: [email protected]
requests must include your name, address and reference number IRC220207Completed application forms must be returned to arrive not later than 12:00 noon (UK time) on Monday 21st August 2017.Applications are particularly welcomed from Roman Catholics and Females as these groups are currently under-represented within AFBI.AFBI is an Equal Opportunities EmployerALL APPLICATIONS FOR EMPLOYMENT ARE CONSIDERED STRICTLY ON THE BASIS OF MERIT
The Institute of Cancer Research, London, Radiotherapy and Imaging, Magnetic Resonance|
The Institute of Cancer Research, London, is one of the world’s most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. We provided the first convincing evidence that DNA damage is the basic cause of cancer, laying the foundation for the now universally accepted idea that cancer is a genetic disease. Today, The Institute of Cancer Research (ICR) leads the world at isolating cancer-related genes and discovering new targeted drugs for personalised cancer treatment.Research within the Imaging Centre at the Institute of Cancer Research (ICR) covers a wide range of measurements, from equipment and technology development and evaluation, through biological studies in cells and animals, to clinical studies.Locally, images are managed via a Research Picture Archiving and Communications System (PACS), which complements the Royal Marsden Hospital (RMH) clinical PACS. The Research PACS is based on the extensible Neuroimaging Archive Toolkit (XNAT) platform (Washington University, St Louis), which is rapidly gaining traction as a leading solution in both clinical and preclinical academic research.At the ICR, XNAT is deployed in three modes, each providing exciting opportunities for gaining experience in enterprise-level technologies:•Identifiable patient data sitting behind the NHS clinical firewall: Data are backed up via a dedicated 200 TB geo-spread object store (disk only, Lattus-M with StorNext, quantum.com).•Anonymised data within the ICR academic firewall: Data are backed up via the ICR’s state-of-the-art 6 PiB research data storage platform.•Anonymised publicly accessible repository: prototype of the new Cancer Research UK national platformOver recent years, ICR has recognized the need for investment in the latest computational resources and has recently commissioned and published a thorough Digital Review. We are seeking a highly motivated and experienced Data Scientist to take an active role in all aspects of the XNAT platform, from cutting edge research in cancer to infrastructure strategy:•data science: use of the platform to perform state-of-the-art analyses of clinical image data, using radiomics and other methods;•software development: enhancement of the platform and creation of associated tools in the “XNAT ecosystem”;•day-to-day management: operational oversight of 5 XNAT instances, including key responsibility in the area of information governance;•interaction with end users: organising induction for new users, following up queries and problem solving;•strategy development: liaison with the ICR’s Department for Data Science to perform integration of image data with “-omics” and other types of cancer data; collaboration with the XNAT development team in Washington University, St Louis; involvement with Cancer Research UK on the national rollout of the XNAT platform.The successful candidate will be working in a stimulating, multi-disciplinary environment, alongside clinicians, physicists, bioinformaticians and biologists. The initial one-year post is likely to be extensible, but given the enthusiastic adoption of XNAT by the academic community, the skills and expertise acquired in the position are also likely to be highly transferrable.The successful candidate will hold a Bachelor’s degree in computer science, physics, mathematics, computational biology or related field. A PhD in a quantitative field is desirable but not essential. In addition to excellent programming skills in both scripting and high-level languages (preferably including Java), web development experience is highly desirable as is previous experience programming for the XNAT platform. Demonstrated ability to deliver software tools, and experience in data integration and visualization are also required. The ability to work on high impact problems in a collaborative environment coupled with excellent communication skills and ability to communicate research findings and methodology, for audiences at a variety of different levels are crucial to this role.The ICR has a great record in employee satisfaction thanks to its competitive salary and benefits packages, environment and career support.To download a full JD and to apply please visit our website.
The ECS Group Limited|
Senior Analyst Method Development|
I am currently looking for a new Senior Analyst in Method Development to join the R&D team of my client's global healthcare organisation, specialising in Inhalation and pharma, based in Loughborough. Overall Mission * Work as part of a team responsible for the testing and development of new inhalation pharmaceutical products as part of a successful R&D organisation. * You will be responsible for leading the development of analytical methods that will be used for the testing of pharmaceutical products. * Supporting the testing of drug products with 'from scratch' methods which will have marginal or zero literature available. * The principal dosage form will be inhalation, and the main technique will be LC. * Work with clients and on new development projects on drug development. * The successful candidate will also be required to have a knowledge of organic chemistry, in order to facilitate full contribution to the development of stability indicating impurity methods. Knowledge & Compulsory requirements * Very knowledgeable in the theoretical aspects of analytical method development with particular emphasis on development of LC methods * Practical experience of the execution of method development and method validation * Knowledge of organic chemistry and experience of relating this knowledge to the prediction of degradation pathways of organic molecules. * Experienced in the validation requirements for analytical methodology in the pharmaceutical industry (MHRA/FDA/ICH etc.) * Experienced in working to GMP (good manufacturing practice) * A track record of problem solving and production of robust methodologies to analyse pharmaceutical products. * Experience of a wide range of instrumental as well as practical experience of "wet" and classical chemistry. * Proven ability to work methodically and pay meticulous attention to detail. * Experienced in the characterisation of organic impurities, with emphasis on utilising LC with mass spectrometry detection as the principal means of elucidation * Broad knowledge of current industry practices, with an established network of relevant external contacts, ideally having history of authoring relevant publications * Working knowledge of analytical method life cycle management, to include Quality by Design and method risk assessments Qualifications * Degree qualified, MSc or PhD in Chemistry and/or Biochemistry * Extensive experience in a method development role in the pharmaceutical industry.
The Job Jobber|
Big Data Lead - 8+ years exp|
Salary: $150,000 - $170,000Essential Functions:As the Big Data Platform Lead, you will define, architect and implement platform wide strategy that meets the needs of customer-facing applications, Data Engineering and Data Science teams.You will define, implement and manage performance, scalability, high availability data pipelines and build scalable and performant dataplatforms.Lead and define data platform architectures for strategic data platforms including Hadoop, noSQL and document stores.Facilitate multi-tenant ETL Flows to process raw data at scale (including Scripting, interfacing with and providing APIs, write SQL queries, etc.).Enhance Data Lake Implementation and work out algorithms to process insight realization with significantly large data payloadsImplement massively parallel, distributed computing and resilient architectureRequirements:8 + years of hands-on experience with designing and implementing large-scale, highly available, and extensible software solutions in Big Data and Business Intelligence space.Proven track record of leading enterprise and solution architecture implementation and adoptionExtensive experience in data in motion and data at rest integration technologies and architecture patternsHands-on proficiency with OLTP, Data warehousing, data lake platform architecture and engineeringCredible experience in data architecture and design, including relational databases, No- Sql, analytics and big dataThorough knowledge of infrastructure architecture design, including cloud-based infrastructureMultiple years of prior experience in application and/or database programming in multiple programming languages and technologies like Hadoop, Scala, Kafka, Pig, Hive, SQL, etc.Fluent knowledge of architecture modelling, including and beyond UML and BPMN, and related toolsAdvanced knowledge of multi-threading concepts.Experience with agile development methodologies (Scrum or similar) is a plus.Experience with Apache Spark, Kafka.QualificationsDemonstrated Technical leadership experience in Software Engineering with enterprise architecture and Product DevelopmentBS, MS or PhD in Computer Science or related fieldAt least 4+ years of experience in dealing with Big Data ecosystems.
King's College London, Imaging Chemistry and Biology|
Postdoctoral Research Associate in Radiation Biology|
Imaging Chemistry and BiologyKing’s College LondonR6/MRV/1518/17-POThe salary will be paid at Grade 6, £32,958 per annum, plus £2,623 per annum London Allowance.This post will be a Fixed Term Contract for 12 months This is a Full-time – 100 % full time equivalent, or Part-time – % to be decided.We are seeking a postdoctoral research associate to work on an exciting 12-month project to determine how therapeutic radionuclides can be used most effectively. Despite the use of radionuclides for therapy becoming more commonplace, their biological effects are poorly understood. This means that we do not know if radiopharmaceuticals are being used to their maximum potential. The aim of this project is to carry out an in-depth and structured set of mostly in vitro and some in vivo experiments to work out under which conditions radioactivity emitting alpha particles and electrons are most effective without harming healthy cells.Candidates with a PhD in radiobiology, biology, pharmaceutical sciences, radionuclide therapy, radionuclide imaging, or radiochemistry will be considered. Independence, initiative and problem solving abilities are prime requirements for this role, as is the ability to work flexibly and collaboratively. In return, the candidate will benefit working in a dynamic highly interdisciplinary environment with state-of-the art imaging facilities. This position is funded by a Springboard Award from the Academy of Medical Sciences.The selection process will include a presentation and a panel interview. Interviews are scheduled to be held the week commencing: 4 September 2017For an informal discussion to find out more about the role please contact Dr. Samantha Terry ([email protected]
)To apply for this role, please go to the King’s College London HireWire Job Board and register to download and submit the specified application form.The deadline for applications is midnight on 20 August 2017 Radiobiology, Molecular Biology, Cell Biology
University of Santiago de Compostela, MONTENEGRO GROUP|
HFSP funded Post-Doctoral Position in Supramolecular Chemical Biology and Synthetic Biology|
The group of Dr. Javier Montenegro (http://javiermontenegrochemistry.com/) is seeking for a Post-Doctoral Candidate with strong interest in Supramolecular Chemistry, Chemical Biology and Synthetic Biology. This is an excellent opportunity to join a Human Frontiers Project, a cutting-edge research aimed towards the fabrication of a minimal cell and a synthetic cytoskeleton (https://www.usc.es/ciqus/en/groups/peptide-nanotubes).The general aim of the project is to prepare and study peptides and other molecules that self-assemble into tubular and fibril networks in the “out of the equilibrium” regime.Description:The applicant will be involved in the preparation of the cytoskeleton of a minimal cell mimic. The research will involve the synthesis of self-assembling peptide building blocks and the biophysical characterization of the resulting ensembles. This project is part of an international project towards a fully synthetic cytoskeleton with self-regulating capabilities. The research groups involved are top-level scientists of the United States (Neal Devaraj - https://www.devarajgroup.com/) and Japan (Toshihide Takeuchi (http://www2.med.osaka-u.ac.jp/neurother/).Requirements:We seek outstanding individuals with initiative, creativity and team-working ability and with a PhD degree in Chemistry, Biophysics, Synthetic Biology, Chemical Biology or Biochemistry.Experience in peptide chemistry, self-assembly, microfluidics and biophysics will be highly considered.Good communication skills and proficiency in written and spoken English are essential.Research Center: CiQUS (www.usc.es/ciqus/en), University of Santiago de Compostela (Spain). Starting Date and Term: Starting date could be flexible during 2017. 2 years of contract (annual evaluation). Deadline: October, 25th 2017. Applications: All the application procedure will be done online. Applicants must fill out the form, attach the required documents and the contact references. This call is also available here in pdf format: (https://www.usc.es/ciqus/sites/default/files/empleo/hfsp_02.pdf) References:“In situ” Functionalized Polymers for siRNA Delivery”, Priegue, J. M.; Crisan, D. N.; Martínez-Costas, J; Granja, J. R.; Fernandez-Trillo, F.; Montenegro, J. Angew. Chem. Int. Ed. 2016, 55, 7492-7495.“Cellular Uptake: Lessons from Supramolecular Organic Chemistry”, G. Gasparini, E.-K. Bang, J, Montenegro and S. Matile, Chem. Commun. 2015, 51, 10389-10402. “Montenegro, J., Vázquez-Vázquez, C., Kalinin, A., Geckeler, K. E., & Granja, J. R. Coupling of carbon and Peptide nanotubes. J. Am. Chem. Soc., 2014, 136, 2484–2491.
Red - The Global SAP Solutions Provider|
Senior Business and I.T Architect|
Senior Business and IT ArchitectWe are pleased to offer you the opportunity to join our prestigious partner and take advantage of; higher salaries than market, training in best practice methodologies and latest technologies, unrivalled career development program and an environment best described as pragmatic & entrepreneurial.Accountabilities:Participation in challenging IT large scale projects for our domestic and multi-national customer baseAccess to cutting-edge innovation programs in order to grow your career with usExcellent networking and knowledge development base in Switzerland and internationallyWe offer you a work environment dominated by a strong team spirit that will allow you to develop both professionally and personallyGiven our customer base, our projects have a strong international flavour and offer you the chance to be self-motivated and creativeYou will join our motivated, multicultural team at our office in Zurich, Basel or BernSkills/Experience:University degree (master's, MBA or PhD)5+ year's professional experience in IT Architecture Design and ImplementationGood understanding of and practical experience in multiple technology stacks as part of major vendor environments as SAP, Oracle and Open Source FrameworksStrong networking skills and ability to work with peopleStrong business & technology acumen in different industriesProven track record in IT/enterprise strategy and architecture developmentStrong experience and broad area of expertise in large scale technology or business transformation programs (enterprise-wide)RED have a well-established relationship with our client so if you are interested in the above and feel that your past experience fits our client's requirements, then please attach your latest CV and a current contact number and a member of our team will be in touch!
Machine Learning Researcher | *Flexible Salaries-DOE* | Bristol|
Machine Learning Researchers Mobile App / Python / Ruby / Shell Scripts Salary: DOE Bristol Based, *Potential for Home Working!* I am looking for multiple Machine Learning Researchers to join a hugely successful mobile app start-up company who are already established in one of the most culturally significant countries globally, and who are now growing an office in Central Bristol to enable a global rollout. This product is having a profound positive effect on health, social connections and environmental sustainability. If you would like to solve real world problems, and have the following skills, please get in touch today! The role: * Work on developing scalable classifiers and tools using machine learning techniques * Research, code and deliver alongside the engineering team to test and release new features * Creatively enhance and adapt well know algorithms and methods to support and inform future roadmaps * Work closely with a team of high performing Machine Learning and Data Science engineers solving real world problems The skills: * Machine learning related work, or MSc or PhD degree in Computer Science or related field * Proven experience in machine learning and data mining * Track record translating product and feature requirements into production ready services * Experience with Python, Ruby, Shell Scripts You could be working on an app visited by over 3 million people p/day which is working to, and succeeding at, building a better world! Is this you? Ensure you email me with an updated CV today via and call me on if you have any questions. People Source Consulting Ltd is acting as an Employment Agency in relation to this vacancy. People Source specialise in technology recruitment across niche markets including Information Technology, Digital TV, Digital Marketing, Project and Programme Management, SAP, Digital and Consumer Electronics, Air Traffic Management, Management Consultancy, Business Intelligence, Manufacturing, Telecoms, Public Sector, Healthcare, Finance and Oil&Gas.
University College London, Institute of Materials Discovery|
Research Associate in Intelligent Nanocomposite Materials|
The appointment will be on UCL Grade 7. The salary range will be £34,056 - £41,163 per annum, inclusive of London Allowance. Applications are invited for a Research Associate to work with Professor Kwang-Leong Choy in the UCL Institute for Materials Discovery. This is an exciting three-year project that aims to discover, design new nanostructured intelligent nanocomposites and optimise them for next generation engineering components and devices at the UCL Institute for Materials Discovery . The research project in which the successful applicant will be involved takes advantage of recent developments in advanced nanocomposite materials. The successful applicant will carry out cutting edge research to design and develop novel nanostructured composites with intelligent properties such as self-maintenance, self-repair, self-replication, self-diagnosis, recognition, learning, adaptivity, information storage, signaling and evolution etc. for a wide range of engineering components and devices. The project involves strong academic and industrial collaboration. In addition to the duties outlined above, the postholder will be required to present results and reports at progress meetings, prepare papers for publication and contribute to project supervision. The appointment is funded by the European Commission for one year in the first instance. A PhD in Materials Science/Engineering, Materials Chemistry, Physics, or similar Science/Engineering degree, with a broad range of relevant backgrounds is essential . The successful candidate will have a keen interest in new materials development, nanocomposites, thin film and coating fabrication technology, materials simulation and characterisation. The project also requires a highly practical candidate with keen interest in designing and upgrading a purpose-built thin film deposition equipment and device fabrication. Please note, appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at Research Assistant Grade 6 (salary £29,809 - £31,432 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis. A job description and person specification can be accessed at the bottom of this page. For further details about the vacancy and how to apply online please go to http://www.ucl.ac.uk/hr/jobs/ and search on Reference Number:1653095 For informal enquiries about the role, please contact Prof. Kwang-Leong Choy: [email protected]
. Please send any queries regarding the vacancy or the application process to Randalle Roberts: [email protected]
as we wish to encourage online applications. Closing Date: 21 July 2017 Latest time for the submission of applications: 23:59. Interview Date: TBC We particularly welcome applications from black and minority ethnic candidates as they are under-represented within UCL at this level. Direct apply link: https://atsv7.wcn.co.uk/saf/login.cgi?owner=5041178&ownertype=fair&jcode=1653095&external=232110
Dublin City University, School of Electronic Engineering|
Postdoctoral Researcher in the Performance Engineering Lab (2 Posts)|
Clearwater People Solutions|
Medical Science Liaison/MSL - Permanent - Various U.K Territories - So|
We have a fantastic opportunity for a Permanent MSL position based at a market leading Therapy specialist operating at a local level. This is a field-based role within the company's key Therapeutic area: Iron Therapy.The MSL is expected to:. Initiate and maintain strong relationships with Key Opinion Leaders (KOLs).. Provide high quality scientific information to health care professionals (HCPs) in response to specific requests.. Take an active role in clinical trials: input into the clinical development plan, study design and protocols to ensure that UK needs are addressed. Proactively identify data gaps and work with relevant stakeholders to fill unmet needs. Drive company-sponsored studies and have full responsibility for assigned investigator-sponsored studies (ISSs).. Proactively identify areas of development for assigned therapeutic area, input into medical plans and the execute medical affairs strategy by taking actions that lead to advances ensuring optimal patient treatment.. Provide scientific support to sales and marketing teams: provide internal scientific training, input into the development of company materials and act as a compliance reviewer for sales/marketing materials.. Develop an excellent understanding of the ABPI Code practice: act as a compliance advisor for internal teams and have the opportunity to develop into a scientific non-final signatory reviewer.REQUIREMENTS:The ideal candidate has a Master's or PhD in medicine, pharmacy or life science and demonstrated commercial acumen.Hold a good understanding of the workings of the pharmaceutical industry and has worked in MSL role or similar Medical affairs position.Has a strong understanding of the NHS; knowledge regarding Irish healthcare system is considered an advantage.Proven track-record of translating scientific or clinical data into messages to help physicians best serve their patients and support change in clinical practices through collaboration with KOLs and strategic stakeholders.The individual would require a strong drive, collaborative mind-set and great communication skills.The successful candidate can expect to reasonably evolve their duties and responsibilities over time, reasonable flexibility is, therefore, a key part of any job. Significant variations in duties and responsibilities should be discussed between the post-holder and manager as they occur.Employees are encouraged to improve and innovate their own roles as well as to highlight improvements and innovations that may be made elsewhere, and gain agreement with your manager how such innovations may be raised or implemented.What is Offered: - Full-time career opportunity with career progression - Market-leading salary will be offered depending on level of experience and skills - Permanent contract of employment with company perks and benefitsWhy this Vacancy is right for you: - Established and successful company. - Investment in employee development.Please send your application with your most recent CV today. To find out more about this career opportunity please call Jacob or email (see below) detailing your interest.Applicants who have not had a response within two weeks should assume their application has been unsuccessful.Clearwater People Solutions are proud to offer a service based on a quality and personalised approach. We work diligently on behalf of our Candidates to find the right role that you and your specialist skill set deserve. Our consultative, honest approach combined with our integrity and full qualification of each-and-every requirement we work make us a perfect partner for you in your search for the ideal position. At Clearwater: your Career is our Job. We look forward to hearing from you.Key Words:Anaemia/Iron deficiency/MSL/Medical Liaison/RML/Regional Medical Liaison/Scientific Liaison/Regional Medical Advisor/Medical Information/South England/Central England/North England
SUNY Upstate Medical University, Center for Vision Research|
Two Postdoctoral positions - Protein aggregation/autophagic diseases in the eye|
Job SummaryTwo Postdoctoral positions are available in the Center for Vision Research at SUNY Upstate Medical University, Syracuse, New York, USA in the lab of Dr. Audrey Bernstein starting July 2017. Project 1: Promoting regenerative healing in the eye. Scarring results from the persistence of myofibroblasts, cells that excessively contract tissue and secrete disorganized extracellular matrix. RNA sequencing of myofibroblasts revealed significant changes in the expression of genes coding for ubiquitin pathway components, including increased expression of a subset of deubiquitinating enzymes (DUBs). This project will 1) investigate the impact of the DUB, USP10 in regulating integrin-mediated scarring and 2) test the efficacy of a self-delivery siRNA therapeutic to promote regenerative healing and prevent scarring in vivo. Project 2: Autophagic Dysfunction in Exfoliation Glaucoma. In Exfoliation Glaucoma (XFG), the leading identifiable cause of glaucoma, the eye accumulates protein aggregates that block the exit of fluid from the eye. Our studies are the first to identify an age-related cellular defect in the autophagy system in patient-derived XFG cells. This project will 1) interrogate the basic mechanisms leading to protein aggregate formation and expulsion from cells, and 2) leveraging the vast literature on neurodegenerative protein aggregation diseases, test novel therapies on patient-derived cells to reverse XFG pathology.Both projects use human primary patient-derived cells, organ culture, molecular and cell biological techniques as well as genetic and proteomic screening. The salary will be according to NIH guidelines, depending on the number of years of postdoctoral experience. SUNY Upstate is a well-funded campus with excellent resources. Syracuse, NY has a high quality of life with beautiful surroundings. http://www.goodyclancy.com/projects/upstate-neuroscience-research-building/Required QualificationsWe are seeking highly motivated and creative individuals with a PhD or MD. Experience in cell culture, molecular biology, and/or ocular surgery on animal models is welcomed. The successful candidate will have excellent organizational and communication skills. Contact:Please send a CV and contact information for 3 references to Dr. Audrey Bernstein ([email protected]
). Web page at SUNY is in progress. Please see http://labs.icahn.mssm.edu/audreybernsteinlab/