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1038335| Ricerca Biosciences, LLC| Senior Study Director| Responsibilities BASIC SUMMARY: Study Director for pilot and IND-enabling studies. Experience in chronic, investigative and carcinogenicity study designs. Responsible for the planning, conduct and successful reporting of assigned studies. Participate in report review and generation process. Develop new capabilities for Ricerca Biosciences. Communicate with Sponsors as required. ESSENTIAL DUTIES AND RESPONSIBILITIES: Participate in the proposal and bid development process Serve as a key contact for sponsors Participate in and coordinate all phases of the study planning process with Client Services and technical and laboratory support operations Responsible for study design and generation of protocols Interpret study data, write reports and draw conclusions Develop and foster business relationships Perform other duties as assigned Qualifications 10+ Years' experience as a Study Director in a CRO setting PhD in Toxicology or Pharmacology or a related field. Ability to interact with multiple personality types and cultural backgrounds. DABT preferred. Additional experience as a toxicologist, or related field in a governmental or industrial setting is preferable. Working knowledge of Good Laboratory Practices regulations Attention to detail and excellent interpersonal and communication skills
7153| University College London, UCL Medical Physics and Biomedical Engineering Wellcome / EPSRC Centre for Surgical and Interventional Sciences, Institute of Healthcare Engineering| Research Associate / Senior Research Associate in Precision Instrumentation for Computer-assisted Intervention Science| The appointment will be full time on UCL Grade 7/8. The salary range will be Grade 7 £34,056 - £41,163 per annum Grade 8 £42,304 - £49,904 per annum, inclusive of London Allowance.The Wellcome / EPSRC Centre for Surgical and Interventional Sciences at UCL invites applications for Medical Physics and Biophotonics Engineering Research Associates and Senior Research Associates with experience in surgical and interventional sciences. This is an exciting opportunity for enthusiastic Researchers / Engineers with relevant skills in this area to join an internationally leading research group. The Centre mission is to translate developments from flagship research projects into clinical tools and bring the duration to first-in-human clinical studies under 5 years. The appointment is available from 1 May 2017 and is funded for 2 years in the first instance. In our System Integration innovation support theme, we require engineers with in-depth mechanical, materials, electronics, mechatronics or optoelectronics engineering expertise, and capabilities in system integration. For our three fundamental research themes (Physiological Navigation - Clinician Experience - Precision Instrumentation), we require researchers/engineers with a broad set of technical expertise underpinning the Centre’s mechatronics platforms and research aspirations. More specifically, we seek applications from researchers / precision instrumentation engineers with expertise in interventional imaging, robotics/instrumentation, and sensing applications. To be appointed at Grade 8 (Senior Research Associate) candidates must be able to demonstrate experience leading a team of researchers and have some evidence of being invited to present at international conferences. An excellent publication record is necessary, while experience of serving on peer-review committees would be desirable. The Appointees will have a strong mathematical and/or engineering background and relevant experience in one or more research areas listed within the person specification. Interested candidates are welcome to contact either Professor Sebastien Ourselin or Dr Tom Vercauteren, email: [email protected] for an informal discussion. For further details about the vacancy and how to apply online please go to http://www.ucl.ac.uk/hr/jobs/ and search on Reference Number 1629242.If you have any queries regarding the application process please contact Neha Shah, HR Manager for advice [email protected] . Closing Date: 17 March 2017UCL Taking Action for Equality.
7145| University of Otago, Wellington, Department of Paediatrics| Postdoctoral Fellow in Bioinformatics (Epilepsy Genetics)| Te Whare Wānanga o Otāgo ki Te Whanga-Nui-a-TaraDEPARTMENT OF PAEDIATRICSTe Tari Mātai Mate me te Hauora TamarikiAn exciting postdoctoral opportunity is available for outstanding applicants with experience in analysing next-generation sequencing data. You will be based at the Epilepsy Research Group at the University of Otago, Wellington, where you will manage epilepsy genetic bioinformatics research projects focusing on the analysis of next-generation sequencing data from family and cohort studies.The Epilepsy Research Group is a high-calibre national epilepsy genetics project with over 1200 individuals participating from around New Zealand. The group has strong ties with world-leading scientists in Melbourne at the Walter and Eliza Hall Institute (WEHI) and the Epilepsy Research Centre, University of Melbourne. The project will be primarily supervised by Associate Professor Lynette Sadleir with Professor Melanie Bahlo at the WEHI. You will have an affiliation with the WEHI as a visiting scientist to the institute and will travel to Melbourne at least twice a year. The bioinformatics analysis will be performed using established analysis pipelines at the WEHI and accessed remotely while in Wellington.Key Tasks:• Appropriate analysis of data using next-generation sequencing analysis tools.• Maintenance and development of data analysis pipelines.• Understanding and interpretation of techniques and results.• Management of a portfolio of epilepsy projects.• Understanding of epilepsy genetics.• Maintain good working relationships with Epilepsy Research Group staff and our research collaborators.• Summarising and reporting key results to collaborators.• Present research results at meetings.• Writing manuscripts reporting the results.• Contribute to the Epilepsy Research Group and Bahlo lab meeting schedule by giving meeting talks (2-3 times pa).• Present work at conferences.• Attendance at Epilepsy Collaborative Group Retreats (twice pa).• Contribute to Grant Funding applications.Knowledge and skills: A PhD in a quantitative discipline such as computational biology, statistics, mathematics, computer science is required, as well as experience in the analysis of next-generation sequencing data and a good understanding of genetics. Experience with family studies is also highly desirable. The successful candidate will have experience in Perl (and/or Python), R programming and post analysis interpretation, as well as report writing and discussion of research results.This is a full-time position fixed-term for two years.Please include the following in your application:• A current curriculum vitae.• If relevant, please also attach a copy of your current work visa.• A cover letter is also required. In your cover letter, please address specifically, with examples, how you fulfil each of the essential and desired person specifications stated in the job description. Please also state why you are interested in the position.Applications quoting reference number 1700249 will close on Monday, 13 February 2017.APPLICATION INFORMATIONTo see a full job description and to apply online go to: www.otago.ac.nz/humanresources/join-otagoEqual opportunity in employment is University policy.E tautoko ana Te Whare Wananga o Otago i te kaupapa whakaorite whiwhinga mahi.
7120| Czech Technical University in Prague, Faculty of Electrical Engineering| Research and Career Opportunities in the Centre for Advanced Photovoltaics at Czech Technical University in Prague| A number of Postdoctoral Research Fellowships and Ph.D. studentships are available in all research areas of the Centre for Advanced Photovoltaics CTU in Prague, including:- Two Fellowships to work on the in silico design of smart self-assembling materials for photovoltaic applications.-One Fellowship in experimental microscopic studies of transient phenomena in PV materials, structures, and complete device.- One Fellowship to work on the fabrication, characterisation and modelling of photonic structures to enhance the capture of light.- One Fellowship to work on the Building Integrated and Building Applied Photovoltaics (BIPV, BAPV).- One Fellowship to work on the theoretical studies and interpretation of optical measurements of novel solid state materials.- One Fellowship to work on the preparations of novel high efficient heterojunction silicon solar cell.- One Fellowship to work on the synthesis and characterisation of organic layers attached to the surface silicon.- One Fellowship to work on the chemical preparation of materials for photovoltaic utilization.Detailed description of all positions is available at http://cap.fel.cvut.cz/The applicants for Fellowships should hold, or be about to obtain, a doctorate in the relevant academic discipline. The appointment will be for three years with probation period of one year. At the end of the three-year period, opportunities will exist for exceptional candidates to apply for longer-term posts (assistant professor). Interested candidates should apply, with an up-to-date CV, a brief statement of proposed research and the names and contact details of two referees to [email protected] The positions can be discussed informally with the leaders of the appropriate research themes. Starting salary will be within the range of Euro 1600 – 2000 per month depending on the qualifications and experience. For all the applicants (Ph.D. Studentships as well as Research Fellowships), knowledge of the Czech language is not mandatory but a good working knowledge of English is essential.The deadline for the first round of applications for Research Fellowships is 24th February 2017. It is intended to hold interviews with the short listed candidates between 3rd and 5th April 2017; applicants from outside Europe will be interviewed by Skype. Further appointments will be made at approximately six-monthly intervals until all positions are filled.
1038334| City of Cleveland| Chief of Clinical Laboratories| Chief of Clinical Laboratories Department of Public Health DUTIES Under general supervision, oversees laboratory work performed within a division to ensure compliance with standards and regulations. Designs and sets up laboratory tests, incorporating quality control and quality assurance procedures. Oversees the training and assesses the competency of laboratory personnel. Assigns duties to laboratory staff. Updates staff concerning new laboratory testing methods. Monitors procedures for compliance with quality requirements and accrediting agencies' regulations and standards. Ensures that laboratory and work environment conditions are safe and clean. Maintains laboratory supply inventory using department procurement tools. Performs other job-related duties as required. MINIMUM QUALIFICATIONS HEALTH - Must satisfy Clinical Laboratory Improvement Act requirements for Lab Director and Clinical Consultant for a High Complexity clinical lab. Must have EITHER a Doctor of Medicine Degree (MD) or a Doctor of Osteopathic Medicine degree (DO) with a current State of Ohio license as well as two years directing/supervising a high complexity lab or one year of clinical lab training in medical school OR. Must possess a PhD in Chemical, Physical, Biological, or Clinical lab science and be certified by an Health and Human Services-approved board (eg: ABMM, ABCC). A valid State of Ohio Driver's License is required. Interested Candidates please click apply. THE City OF CLEVELAND IS AN EQUAL OPPORTUNITY EMPLOYER
1038304| Consol Partners| ASIC Design Methodology Engineer| Candidate will be working as part of a team supporting introducing new technology to design team. The team works in close collaboration with our internal team design teams spanning from architecture to physical design. The responsibilities of candidate are to accurately predict the impact of process changes on design and architecture and to optimize the PPAC of our product. To achieve this target, candidate needs to do a lot of experiment spanning spice level simulation, standard cell design, place &routing and so on. QualificationsMaster or PHD in Electrical Engineering, Computer Engineering or related disciplineMore than 2 years' experience in SRAM or Standard cell designMore than 2 years'experience in IC physical design covering the whole flow, floorplan, partition, power plan, placement, CTS, routing, physical verification, power verification, STA. Have in-depth knowledge in semiconductor process and device.Skills in C/C++, Perl, TCL, python, Shell Scripting is a strong plus
7147| Institute of Food Research, Gut Health and Food Safety Programme| Research Scientist| Applications are invited for a Research Scientist to work on a 3 year project in the Gut Health and Food Safety Programme at the Institute of Food Research, investigating the metabolism of sialic acid by gut bacteria. The post-holder will carry out in vitro work (anaerobic cultures, heterologous expression, enzymatic assays), in vivo colonisation (mouse models) and contribute to carbohydrate (NMR, HPLC, MS) and microbiome analyses (16S sequencing). A PhD degree in Biological Sciences and previous research experience in molecular biology, microbiology and protein/carbohydrate chemistry is essential. The post-holder will work closely with collaborators on the Norwich Research Park involved in the project. In addition to the proposed experimental work, the post-holder will contribute to the research by interacting with Research Scientists and PhD students in the Juge Group, writing-up reports and publications, and presenting at relevant meetings and Conferences. The post-holder will also be encouraged to join public engagement activities. In addition, they will benefit from regular BBSRC-sponsored training courses in career development and transferable skills. In 2018, research teams from IFR, the University of East Anglia’s Faculty of Science and Norwich Medical School and the Norfolk and Norwich University Hospitals’ gastrointestinal endoscopy facility will integrate into the Quadram Institute, a new interdisciplinary research institute at the forefront of a new era in food and health research at the heart of the Norwich Research Park. (http://quadram.ac.uk/).Salary on appointment will be within the range £30,750 to £37,750 per annum depending on qualifications and experience. This post is for a contract of 3 years. For further information and details of how to apply, please visit our web site http://jobs.ifr.ac.uk or contact Human Resources, Norwich BioScience Institutes Partnership, Norwich Bioscience Institutes, Norwich, NR4 7UA, UK, 01603 450462 quoting reference 1003190.We are committed to equal opportunities and welcome applications from all sectors of society. The Institute supports equality of opportunity within the workplace and expects all employees to share and display these values. To support our commitment, we have a range of family, faith and diversity friendly working arrangements to help all staff achieve excellence in their area of work.As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. The closing date for applications will be 7th March 2017. The Institute of Food Research is a registered charity (No 1058499) and is an Equal Opportunities Employer.
7129| University of Oxford, RDM - Division of Cardiovascular Medicine| Postdoctoral Researcher in Anti-Inflammatory Therapeutic Peptide Development| An opportunity has arisen for a Postdoctoral Researcher in Anti-Inflammatory Therapeutic Peptide Development. You will join a team of researchers developing a number of novel anti-inflammatory therapeutic peptides called evasins that we have identified from tick saliva. You will analyse the data from these experiments and present them internally (group meetings) and externally (scientific papers and conferences). Working under the guidance of Professor Shoumo Bhattacharya, the post offers a unique opportunity to develop a skill set and research profile in the field of anti-inflammatory therapeutic peptide development in cardiovascular and other diseases, with opportunities for networking and collaborating with local and international research groups of outstanding reputation.You should hold a PhD (by the time of appointment to the post) in Pharmacology, Chemical Biology or Biochemistry or other relevant discipline. You will also need to have experience with protein expression and purification, biophysical analysis of proteins (e.g. Kd determination), cell culture and cell based assays. Experience with molecular biology technology including E.coli, plasmid design & construction, cloning, PCR, mutagenesis is also essential.This 3 year post is based at the Wellcome Trust Centre for Human Genetics, Oxford and you would be expected to start on 1st June 2017 (or as soon as possible thereafter). Informal enquiries in advance of the application deadline should be directed to Professor Bhattacharya [email protected] . All enquiries will be treated in strict confidence; they will not form part of the selection decision.Applications for this vacancy are to be made online; you will be required to upload a supporting statement and a copy of your CV as part of your online application. To apply for this role and for further details, including a job description and person specification, please click on the link.Only applications received before midday on 10th March 2017 can be considered.Interviews are scheduled for 21st March 2017 The University is an Equal Opportunity Employer
7116| Medical Research Council, Mammalian Genetics Unit| Post-Doctoral Training Fellow| Post-Doctoral Training Fellow (MGU 429)Neurodegeneration & Gene TargetingMRC Mammalian Genetics Unit Harwell, Oxfordshire£27,629 to £32,975 (plus allowances)Fixed Term - 47 monthsAbout UsWe are based at the MRC Harwell Institute, a major international research centre at the forefront of studies in mouse genetics and functional genomics (www.har.mrc.ac.uk). We are advancing medicine through the discovery and investigation of mouse models of human disease; join us to help improve human health.About the RoleYou will be part of a joint programme between groups at MRC Harwell and University College London to create and to characterize bespoke mouse models for answering specific questions in neurodegenerative diseases. This is a 47-month training and development position for a post-doctoral scientist who has recently completed their doctoral studies. This is an exciting position, joining a new group and collaborating within a larger MRC Harwell–UCL Institute of Neurology programme studying neurodegeneration (for example, amyotrophic lateral sclerosis, Alzheimer disease). The group will be run day to day by an experienced Senior Investigator Scientist, Dr. rer. nat. Edgar Kramer, in collaboration with Professor Elizabeth Fisher at UCL, who holds an honorary position at MRC Harwell. The group will be supported by two dedicated laboratory technicians. Please see for more detail the internet site: https://www.har.mrc.ac.uk/research/lifetime-studies/mouse-models-neurodegeneration About YouYou will need:• A PhD in appropriate discipline, e.g. Genetics, Cell Biology, Molecular Biology• A proven track-record in carrying out scientific research to an international standard, e.g. publications/presentations at meetings• Successful experience in gene targeting/genome engineering/gene editing in miceBenefitsWe are strongly committed to your personal development and well-being, with extensive opportunities for training and flexible working. Choosing to come to work at the MRC means that you will have access to a whole host of benefits, from a final salary pension scheme and 30 days of holiday entitlement plus bank holidays, to access to employee shopping/travel discounts and salary-sacrifice cycle to work scheme and childcare vouchers.For full details of this post and to complete an online application, visit https://mrc.tal.net/vx/lang-en-GB/appcentre-1/candidate/postings/468 and upload your CV, along with a covering letter stating why you are applying for this role. Please quote reference number MGU 429.Closing date: 24th February 2017
1038328| The Job Jobber| Software Engineer-Components&Subsystems (photonics, optics etc)| Salary: $90,000 - $120,000Software Engineer - multiple openingsSummaryDesign and development using C, C++ and MATLAB.Design hardware interfaces and GUIsDevelopment of firmware, device drivers, APIDevelop vision processing algorithms for signal extraction, noise reduction and target identificationDevelop software for new products on Windows and Linux platformsWork independently as well as part of cross functional teamsOur client is a leader in providing components and subsystems to the automotive and other industries. These include photonics, optics, mapping and image recognition for autonomous vehicles, cameras, etc.Excellent opportunity for a experienced software engineers to develop state of the art image processing and mapping products.Positions are open due to expansion!Requirements:BS degree in a technical discipline (EE, CS, CE, etc.) MS or PhD preferred5+ years related experienceEmbedded firmware development experienceKnowledge of Ethernet, USB, etc. communication and vision protocolsExperience with image recognition, signal processing, computer vision, AI, machine learning, or robotics greatly desired. Automotive or autonomous vehicle experience a big plus.
7140| University of Tartu, Institute of Biomedicine and Translational Medicine| Research Fellow of Clinical Genomics and Personalized Medicine| Duties and responsibilities:We are seeking four highly motivated and experienced post-doctoral research scientist with a background in molecular biology / functional genomics and epigenetics / cell biology / reproductive and epithelial physiology/ to join the research team of the recently appointed ERA Chair (Senior Research Fellow Alireza Fazeli) in the Institute of Biomedicine and Translational Medicine, University of Tartu. The research fellows will work closely with the ERA Chair team. The ERA Chair research team is focused on investigating the mechanism of complex diseases such as infertility and chronic inflammatory diseases. The Department of Pathophysiology in the University of Tartu has excellent genomic, epigenomics, proteomics, cell biology and animal model investigation systems. The principal task of the research fellows will be to devise and conduct research projects in close collaboration with the ERA chair to understand the intercellular communication and epigenetic basis of the gametes- and embryo-maternal communication as well as inter-cellular communcation during chronic inflamatory diseases. Duties and responsibilities:The post holder will be responsible for:• The design of study protocols and perform experiments in close collaboration with ERA Chair• Supervision of PhD students involved in the project• Collaboration with other members of the research group• Reporting and publishing of obtained results• Participation in knowledge transfer and public awareness activities• Participation and input into commercialisation activities Required qualifications:research degree or an equivalent qualificationRequired experience:We seek candidates who may have some of the following expertise: Molecular Biology • Cell culture • Proteomics • Functional genomics and epigenomcs • Transcriptomics • Maternal communication with gametes and embrüo • Genetics of complex diseases • Genetic epidemiology Experience and/or willingness to participate in knowledge transfer and public awareness activities is considered a strong plus. Any experience working on the commercialization of research will also be a plus. The candidates with following experiences would be prefered: • Experience of work in a R&D institution or University at postdoctoral level • Evidence of peer reviewed publications in high impact factor journalsRequired language skills:The candidate’s English skills must be sufficient for communication and writing in his or her speciality.Additional infoFurther information: Potential applicants are strongly encouraged to take informal contact with Senior Research Fellow Alireza Fazeli ([email protected]) for further information about the post-doctoral position vacancies. Recruitment process: Applicants interested should submit a CV, two references and a letter of interest. Applicants may be asked for telephone interviews as part of the decision-making process.Starting at 01.04.2017, temporary contract to 31.03.2018Workload 1,00; and the classroom teaching load up to 64 academic hours per calendar yearSalary is negotiable, remuneration based on UT Salary Rules.Application documents and notification of results:In order to be considered for the position, the candidate must submit to the UT Human Resources Office (email: [email protected]; postal address: 18 Ülikooli St,Tartu 50090 ESTONIA) following documents:1) a letter of application to the Rector (in Estonian or English),2) a curriculum vitae in the established format (in Estonian or English),3) a list of research publications (if necessary, enclosing copies or offprints of more important publications),4) a copy of a document (including its annexes) which shows the candidate to hold the required qualification (authorized translation into Estonian, English or Russian if the credential is not in one of these languages). A candidate can be required to submit the original or a certified copy of the document (including its annexes) showing the candidate to hold the required qualification. If the candidate has acquired the higher education in question abroad, he or she may be required to submit an assessment issued by the Academic Recognition Information Centre (the Estonian ENIC/NARIC) of his or her qualification in respect of the qualification requirements for the position;5) other materials considered relevant by the candidate (a list of such materials must be included in the application or annexed to it).Candidates for the position of professor or lead research fellow shall present a statement not exceeding 1500 words of the aims to be achieved during the term in the position, and the outline of an action plan for achieving these.Number of copies: 1Notification of results: The candidate will be notified of election results within two weeks following the election. The assessments drawn up in respect of the candidate and the documents specified in paragraph 5 of the list of documents will be returned to the candidate. Unsuccessful candidates can also request the return of documents specified in paragraphs 2 -4 of the list.
7166| University College London, UCL Medical Physics and Biomedical Engineering Translational Imaging Department| Research Associate/Senior Research Associate in Image-Guided Neurosurgery| The appointment is full time and will be on UCL Grade 7-8. The salary range will be Grade 7 £34,056 - £41,163 per annum / Grade 8 £42,304 - £49,904 per annum, inclusive of London Allowance.This is an exciting opportunity for a researcher with skills in scientific computing to join an internationally leading university research group. The aim of the project is to have an active role in the full lifecycle of a surgical planning system for epilepsy neurosurgery. The main purpose of this post is to develop novel methods for automated and interactive planning of neurosurgical interventions and to implement cutting edge real-time visualization techniques for patient specific multi-modal data. The project has a strong translational focus, and excellent software development skills are required to design, document, implement, test and deliver a working planning tool for daily clinical use at the National Hospital for Neurology and Neurosurgery (NHNN). This post is funded for 24 months in the first instance. Candidates must have a PhD, equivalent qualification, or equivalent industrial experience, in image computing, medical image analysis, computer vision or a closely related field. Candidates must possess a first or upper second undergraduate degree, or equivalent in Computer Science, Engineering, Physics, Mathematics or a related subject and be able to demonstrate excellent verbal and written communication skills. Candidates must have demonstrable experience of C++ programming and software development in a collaborative development environment. Familiarity with version control using software such as Subversion or Git is preferable. An in-depth working knowledge of medical image analysis and/or image-guided surgery, as evidenced by a PhD or equivalent degree or equivalent industrial experience is essential. A demonstrable interest in biomechanical modelling and tissue dynamics is preferable. Experience with GPU programming, for example CUDA or OpenCL is desirable. In addition, experience of developing clinical-grade software-based medical devices (including knowledge and experience of standard software design and development processes for CE marking and/or FDA approval) is desirable. To be appointed at Grade 8 (Senior Research Associate) candidates must be able to demonstrate experience leading a team of researchers and have some evidence of being invited to present at international conferences. Experience of serving on peer-review committees would be desirable. For further details about the vacancy and how to apply online please go to http://www.ucl.ac.uk/hr/jobs/ and search on Reference Number 1628386 Further information about the Translational Imaging Group can be found at: http://cmictig.cs.ucl.ac.uk/ If you have any further queries please contact Professor Sebastien Ourselin: [email protected] The Department of Medical Physics and Biomedical Engineering holds an Athena SWAN Bronze Award which recognises and celebrates good practice and commitment to advancing women’s careers in science, technology, engineering, maths and medicine (STEMM) in higher education and research. The award reflects our commitment to the advancement and promotion of diversity and equality. For further information please visit https://www.ucl.ac.uk/medphys/dept/athenaswan Closing Date: 17 March 2017Latest time for the submission of applications: 23:59.Interview Date: TBCUCL Taking Action for Equality.
7134| University of Freiburg, Genetics Institute| Epigenetic Regulation of Plant Stem Cells| We are seeking highly motivated postdoc candidates to investigate how stem cells in the root meristem sense and adopt to environmental changes. A specific focus will be on the epigenetic regulation of stem cells during this process. Background: Unlike most animals, plants can grow and form new organs throughout their life, which in the case of some long-lived trees can last for more than thousand year. The cells for this are supplied by pluripotent stem cells in the proliferative centers plants, the meristems. In addition to their longevity, plant growth and thus stem cell activity must adjust to environmental signals, such as season, light, water and nutrient supply. How active stem cells can be maintained for such a long time and accurately form new organs and how they can sense and adopt to environmental conditions is a central question for both, stem cell biology and agriculture. Our group previously has shown that the stem cells of the shoot meristem are regulated by a local negatively feedback look between the transcription factor WUSCHEL (WUS) and the signaling peptide CLAVATA3 (Mayer at al, Cell 1998; Schoof et al, Cell 2000). We also found that the root meristem functions in a similar way, expressing the WUS homolog WOX5 (Sarkar et al., Nature 2007). WOX5 is required to maintain the stem cells forming the gravity sensing columella pluripotent but also can reprogram already differentiated cell to induced pluripotent stem cells (iPS). The way WOX5 work is that it changes the chromatin of the stem cells by recruiting a histone modifying enzyme to the DNA of its target genes, and as consequence, the Chromatin becomes compacted and the genes silenced (Pi et al., Developmental Cell, 2015). The columella stem cells are a prefect model to study stem cell regulation, because it consists only of three cells types, the niche cells, called quiescent center, that signal to maintain stem cells pluripotent, the dividing stem cells, and their differentiated daughter cells, the gravity sensing columella cells. The root stem cells must adopt to a number of abiotic and biotic environmental challenges including drought, flooding, nutrient shortage, soil contamination but also bacteria and fungus infections. Understanding how stem cells cope with these conditions to maintain root growth is not only of highest importance to stem cell biology, but also for agriculture, especially considering the global climate change.Goal: Understand how the genetic and epigenetic networks that regulates stem cells are affected and respond to environmental signals to cope with adverse conditions.Methods: In addition to standard genetic and molecular tools, the projects utilizes a novel microfluidic technology that is developed together with our engineering partners. This set up allows to simulate environment conditions with simultaneous 3-dimensional live imaging of cells and of fluorescent reporter proteins. Transcriptome, chromatin, and live imaging data will be combined to create models of how regulatory networks of stem cells cope with changing environmental conditions. We will test the role of specific genes by creating CRISPR/CAS9 induced mutants and comparing how environmental adaptation changed compared to wild type. Results will finally be used to formulate breeding concepts with our collaborators at the Shandong Agricultural University in Tai'an (China) to improve root growth under adverse conditions, such as drought or compromised soil.Lab detailsThe lab language is English. German is not required. For further information, also on our publications, please visit our homepage (www.biologie.uni-freiburg.de/LauxLab). The University of Freiburg with a strong and international scientific community is routinely among the best German Universities in international rankings, and advanced facilities for systems biology, protein analysis, and imaging are available. The city of Freiburg is located in the black forest, next to France, Switzerland, and the Alps.How to applyPlease send your CV including your research experiences and your future interests to Thomas Laux ([email protected]).
1038329| The Job Jobber| Computer Vision Engineer| Salary: ConfidentialClient is transforming the way Commerce is done.The ideal candidate will be part of the new App group utilizing Walk Out Technology,  powered by  computer vision, sensor fusion, and advanced machine learning.  If you are passionate about pushing the state of the art in computer vision, machine learning, distributed systems and hardware design, this may be the ideal role for you.You will solve problems that span a variety of domains: computer vision, image recognition, machine learning, Real Time and distributed systems. As a Computer Vision Research Scientist, you will help solve a variety of technical challenges and mentor other engineers.You will play an active role in translating business and functional requirements into concrete deliverables and build quick prototypes or proofs of concept in partnership with other technology leaders within the team.You should be comfortable with a degree of ambiguity that's higher than most projects and relish the idea of solving problems that, frankly, haven't been solved at scale before - anywhere.  A minimum of a BS degree with 4 years experience OR Masters/PhD with 2 years experience.
1038234| Miller Ag| Senior Director Agrochemical Development| Senior Director Agrochemical Development As a part of the Executive team, the main focus of this role is to promote our client's Bioscience's Agrochemical Development and expand our client base while fostering strong client relationships. Act as a liaison between external clients and the management and operational teams. The primary emphasis of this position will be to oversee the operations of teams that perform environmental fate, plant and animal metabolism, residue and physical chemistry studies. The successful candidate will have an understanding of study designs and the regulator requirements for these areas. The objective will be to complete studies on time, with quality and with excellent communication with the client. The primary measure of the success in in this role will be the achievement of annual revenue targets set by Executive and Business management. Responsiveness and Delivery to Promise will be the watchwords of the professional. This will include timely communications with clients (call-backs with one business day) and a sense of urgency around projects and deliverables. A Degree in life sciences required, PhD is preferred. Minimum of 5-7 years' experience. The requirements listed above are representative of the knowledge, skill and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. Miller Ag is a leading Agricultural Executive Search Firm in the US. Our client's pay all fees, relocations costs if needed and offer an excellent corporate benefits package. About the CompanyMiller Ag is a leading Agricultural Executive Search Firm in the US. Our client's pay all fees, relocations costs if needed and offer an excellent corporate benefits package. If interested in any of these or other positions with Miller Ag please send us your resume in confidence! See If these don't fit your needs please tell friend!
7126| Division of Molecular Pathology, ICR, The Institute of Cancer Research| Postdoctoral Training Fellow – Computer Vision| We seek a Postdoctoral Training Fellow to join the Yuan lab at The Institute of Cancer Research, London (ICR) and work on the TRACERx project, the largest study of lung cancer evolution in a collaboration with Prof. Charles Swanton at the Francis Crick Institute. The main focus of the Yuan lab is to develop new computational approaches for studying cancer by fusing computer vision, machine learning and bioinformatics (www.yuanlab.org). Different from traditional cancer-centric approaches, we study cancer from a novel perspective: as evolving ecosystems. Aided by technological advances, we use ecological principles to help us understand why cancer is so difficult to treat – by studying not only cancer cells but also normal cells around them – and discover new ways to target these diseases, akin to draining the swamps to get rid of mosquitoes as one way of eradicating malaria. This is a rare opportunity to collaborate with the world-leading Swanton team and several major universities and hospitals in the UK. Together we aim to reveal the evolutionary dynamics of lung cancer in this pioneering study. You will lead the development of new histology image analysis system for lung cancer. We expect this exciting project to enable the discovery of new biomarkers and clinical innovations to change the way we treat lung cancer.You will join a team of computer scientists, physicists, and mathematicians, working closely with clinicians in the vibrant centre of cancer research discovery and therapeutics at ICR London in the endeavour to cure cancer. You will enjoy the highly collaborative nature of this project, have the opportunities to learn about the latest biotechnologies and travel to conferences, and excel in coordinating between programming and broadening horizons in medicine.ICR were ranked first in the Times Higher Education league table of UK university research quality from the most recent Research Excellence Framework (REF 2014) for our high impact publications. We are world leaders in identifying cancer genes, discovering cancer drugs and developing precision radiotherapy. Together with our hospital partner The Royal Marsden, we are rated in the top four centres for cancer research and treatment worldwide. Our Cancer Research UK Cancer Therapeutics Unit is the largest academic cancer drug discovery and development group worldwide. We discover more new cancer drugs than any other academic centre in the world. Applicants must hold a PhD in Computer Science, Systems Biology, Engineering, Ecology or Statistics. Good programming skills, preferably in R, Matlab, Python or C, and experience in computer vision, machine learning or statistics are essential. Appointment will be on a Fixed Term Contract for 3 years, with a starting salary in the range of £29,960 to £42,820 p.a. inclusive, depending on postdoctoral experience. The expected start date is 1 April 2017 with flexibility. The successful candidate will be based in Sutton, Surrey.To apply, please upload your CV and covering letter (including the names and contact details of two referees) online. To apply please include the following to your application:• A full CV with a publication List• Covering letter including the names and contact details of two referees• Research plan (one to two pages outlining your current research interests and research plans for the next 3 years)
7112| University of Basel, University Children's Hospital/Department of Biomedicine| Postdoctoral Position in Experimental Leukemia Research| We are seeking a highly motivated and career-oriented postdoctoral fellow (PhD or MD-PhD) to complement our team at the Department of Biomedicine of the University Children’s Hospital in Basel/Switzerland. Our group establishes models to functionally study genetic alterations that are involved in the development, maintenance and relapse of acute leukemia (Stavropoulou et al., Cancer Cell, 2016; Picaud et al., Cancer Research, 2015). Potential candidates must have a practical experience in cellular and molecular biology, biochemistry and mouse experimentation. Practical knowledge in bioinformatics data mining is a plus. The Department of Biomedicine of the University of Basel hosts over 30 different research groups and offers an international stimulating and friendly atmosphere in an attractive city, rich in culture, located in the middle of Europe.More information can be obtained at: http://biomedizin.unibas.ch/research/research-group-details/publications/researchgroup/childhood-leukemia/The position will be open from April 2017. For applications and further inquiries, please contact [email protected] Juerg SchwallerChildhood leukemia groupUniversity Children’s Hospital (UKBB)Department of Biomedicine, ZLFHebelstrasse 20CH-4031 BaselSwitzerland
7138| MRC, LMB| Postdoctoral Scientist - Structural Studies - LMB 446| Postdoctoral Scientist – Structural StudiesStarting Salary £30,162 to £32,975 per annum MRC Laboratory of Molecular Biology, Cambridge UKWe are looking for a postdoctoral scientist to join the group of Prof Julian Gough to work on personal genomics. Specifically, to undertake research to investigate connecting phenotype to genotype through molecular biology. There is established research in the group on genetic variant analysis (FATHMM) and functional and phenotype prediction (dcGO) which also builds on previous bioinformatics tools and resources. This project is to bring together our previous research in these areas and apply it to personal genomics, by connecting phenotype to genotype through molecular biology. The project includes analysis of both coding and non-coding genetic variation. The work is anticipated to be predominantly computational and theoretical but could optionally include some laboratory validation or follow-up work.You are highly motivated, have a PhD in a relevant subject, and you have an aptitude for computational work and data analysis. The post is available to applicants with varying computational experience. Applicants with no formal training in computational or mathematical work but who enjoy it, have self-taught to a high level, have a strong aptitude for it and are keen to learn will be considered, if they have other complimentary biological qualifications, knowledge and experience. Conversely computer or technical scientists with no formal training in molecular biology will be considered if they have a powerful interest and motivation in molecular biology and are driven to learn.The successful applicant will be awarded a 3 year Career Development Fellowship/MRC Postdoctoral Training Scheme. The fellowship is a training and development position for a Postdoctoral Scientist who has recently completed their doctoral studies, or is moving into a new research discipline. There will also be the opportunity to work with biotech companies in the Cambridge area to translate the technology for medical use and commercialisation.Working for the MRC provides a whole host of benefits including a final salary pension scheme, Benenden Healthcare membership and excellent holiday entitlement. You will also have access to employee shopping/travel discounts, on site sport and social facilities, as well as salary sacrifice cycle to work schemes and childcare vouchers. The MRC Laboratory of Molecular Biology is one of the birthplaces of molecular biology and is an internationally renowned centre for fundamental biomedical research. The LMB has a strong track record in training Postdoctoral Fellows who have gone on to become leading Scientists. We also have an excellent record of innovative basic research leading to applications in medicine. Scientists are drawn to the LMB from all over the world, thus creating a lively and international community for the exchange of ideas and technical innovation. For further information of the research undertaken at the LMB, please visit:http://www2.mrc-lmb.cam.ac.uk Informal enquires may be made to Julian Gough at: [email protected] apply and access full details of the vacancy please visit our job board at https://mrc.tal.net/vx/lang-en-GB/appcentre-1/candidate/postings/493. If you are unable to apply online please contact us at [email protected] .Closing date: 6 March 2017Final appointments will be subject to a pre-employment screening. The Medical Research Council is an Equal Opportunities Employer who participates in the Disability Confident scheme
1038324| Henley Silk Consulting| Expert Java/C# Developer Required. Excellent Benefits| Based in the UK with headquarters in London, our client is a rapidly expanding software house. Building bespoke, business critical, systems for Blue Chip Organisations there is a requirement for an expert, experienced, Java or C# Developer to play a central part in project deliverables. The Role: You will be an expert C# or Java developer and a keen team player. Working in a collaborative environment and adhering to the latest agile methodologies, you will be passionate about developing applications the 'right way'. The role is hands-on and client facing where you will be involved in the full development life cycle. You will need: You will be an expert in your chosen development language. 5+ years experience in Java/C# programming. Educated to degree level - MSc or PhD. Proven commercial Java experience, preferably enterprise scale. Good OO design principles and patterns. Experience of the Full Software life cycle. Agile methodologies. Adaptable team player, keen to learn new technologies. Nice to have: HTML5 experience. Knowledge of Server Side, scalable, applications - REST, Spring, SQL/NoSQL etc. Javascript experience. Open Source contributions. Consultancy experience. Market leading salary, commensurate with experience. Negotiable. Excellent Benefits. The role is based in London/Newcastle/Edinburgh or Bristol. Rapid career progression is available to the ideal candidate. If you feel you have the necessary skill and experience, then please send me your CV.
1038292| Consol Partners| 5G Radio Algorithm Expert/Engineer/Developer| 5G Radio Algorithm ExpertLocation: Stockholm, SwedenJob Type: 12 month contract + extensionStart: ASAPThe CompanyConsol Partners client is a well-known global telecommunications company that has been running for around three decades. They are still continuing to grow in their historic market as well as growing and expanding into brand new areas. They are focused on innovation and dedicated to hiring the most skilled people in the market.The RoleMy client is developing advanced receivers, advanced antenna systems and on radio resource management algorithms. This is project with universities all over Europe to find the next technological breakthroughs. If this sounds like an interesting challenge where your background will be appreciated, then you should consider the following positions.The IndividualMinimum qualifications 5+ years of experience in radio network algorithm development for cellular networks. Solid background in at least one of the areas radio resource management, SON or machine learning. Up-to-date knowledge about new research trends in academia. Experience in modelling and radio network simulations. Good knowledge in L2 scheduler algorithms.Preferred qualifications A PhD degree in electrical engineering or equivalent. A solid theoretical background in areas such as optimization and machine learning.Ideally we want someone with a background in machine learning as this is more important that the wireless aspect Knowledge of C/C++.
7161| King Abdullah University of Science and Technology, Vibrational Imaging Lab, Biological and Environmental Science & Engineering Division| Postdoctoral researcher in label-free imaging based on broadband Coherent Raman micro-spectroscopy| A postdoctoral researcher position is currently available in the Vibrational Imaging group, headed by Prof. Carlo Liberale, in the Biological and Environmental Science & Engineering Division at King Abdullah University of Science and Technology (KAUST, Saudi Arabia).The Liberale group is a multidisciplinary team of physicists, engineers and biologists committed to the development and application of new-generation label-free microscopy methods for biomedical research. The laboratory is equipped with cutting edge instruments and technology in the field of vibrational micro-spectroscopy. Additionally, KAUST offers exceptional infrastructure for scientific research and is equipped with state of the art core facilities for imaging, characterization and micro-\nano-fabrication.An innovative high-speed broadband Stimulated Raman Scattering system will be designed and set up in our laboratory, in the framework of a recently awarded grant, in collaboration with Prof. Giulio Cerullo and Prof. Dario Polli (Politecnico di Milano).We are looking for ambitious and self-motivated candidates to work on the set up and application of the Stimulated Raman Scattering system, in a collaborative and interdisciplinary project involving radiation-matter interaction, nonlinear optics, ultrashort laser pulses, detectors, electronic instrumentation and finally investigating lipid dysregulation in cancer.A Ph.D. degree in engineering, physics, or a related field is required. Proficiency using Matlab and Labview is preferred. The candidate must have hands-on experience with optical setups and ultrashort pulse laser sources. Experience in Multivariate Analysis of spectroscopic data will be considered a plus.Highly competitive PostDoc salary is provided. Benefits: free housing; relocation support; life insurance; subsidized medical and dental insurance; one round-trip airline ticket per year to visit home country.Applications should include: a CV; a cover letter that summarizes the research experience and areas of interests of the applicant; contact information of at least 2 professional references.The postdoctoral position will be open until filled.
7118| MRC Laboratory of Molecular Biology, Structural Studies| Postdoctoral Scientist| Postdoctoral Scientist – Structural StudiesStarting Salary £30,162 to £32,975 per annum MRC Laboratory of Molecular Biology, Cambridge UKApplications are invited for an experienced postdoctoral researcher to work in the laboratory of Dr David Neuhaus at the MRC LMB Cambridge, in a collaboration with Dr Kevin Embrey at AstraZeneca. The successful applicant will join a project working on the structural and mechanistic basis of a key multi-domain enzyme involved in DNA repair and tumorogenesis, using solution state NMR spectroscopy as the main tool. The project aims to establish how different types of DNA damage are recognised by combinations of protein domains, as well as characterising DNA-dependent inter-domain interactions and dynamics that underlie enzyme activation. State-of-the-art NMR experiments will be used in conjunction with a variety of stable-isotope labelling strategies, in addition to other biophysical and biochemical approaches as needed. You should have extensive previous experience in protein NMR spectroscopy to at least PhD level, including preparation and purification of isotope labelled proteins; experience with expressing and purifying deuterated protein samples, as well as with other biophysical and biochemical techniques for characterising protein-DNA interactions would be an advantage. You should be able to demonstrate skills in working independently and within a team to solve experimental problems.The successful applicant will be awarded a two year Career Development Fellowship/MRC Postdoctoral Training Scheme with a potential 3rd year extension following assesment by the funder. The fellowship is a training and development position for a Postdoctoral Scientist who has recently completed their doctoral studies.The MRC Laboratory of Molecular Biology is one of the birthplaces of molecular biology and excels at deciphering the molecular mechanisms of life. It provides an unsurpassed environment for both new and established researchers. Scientists are drawn to the LMB from all over the world, creating a lively and international community for the exchange of ideas and technical innovation.Working for the MRC provides a whole host of benefits including a final salary pension scheme, Benenden Healthcare membership and excellent holiday entitlement. You will also have access to employee shopping/travel discounts, on site sport and social facilities, as well as salary sacrifice cycle to work schemes and childcare vouchers.For further information of the research undertaken at the LMB, please visit:http://www2.mrc-lmb.cam.ac.ukInformal enquires may be made to Dr David Neuhaus, e-mail: [email protected] apply and access full details of the vacancy please visit our job board at https://mrc.tal.net/vx/lang-en-GB/appcentre-1/candidate/postings/477. If you are unable to apply online please contact us at [email protected] .Closing date: 1 March 2017 Final appointments will be subject to a pre-employment screening. The Medical Research Council is an Equal Opportunities Employer who participates in the Disability Confident scheme
7164| Earlham Institute, Platforms and Pipelines| Platforms and Pipelines Bioinformatician (Maternity Cover)| We have a great opportunity at Earlham Institute for a Bioinformatician to join our Platforms and Pipelines Group who are responsible for delivering the BBSRC National Capability in Genomics. This group provides access to state of the art genomics technologies for research groups throughout the UK as well as delivering sequencing and genomics services to the associated Science Faculty groups and commercial customers.The P&P Bioinformatician post will focus on performing primary data analysis for research projects from a wide variety of Next Generation Sequencing (NGS) platforms, including Illumina HiSeq, MiSeq, PacBio RSii, Sequel, and associated large molecule technologies such as Oxford Nanopore, BioNano Genomics and 10x Genomics. These projects cover practically every NGS application from genome assembly, amplicon resequencing, exome capture, CHIP-Seq, RNA-Seq miRNA-Seq and metagenomics.This maternity cover position will join a team of 3 bioinformaticians and a Bioinformatics Manager and will be responsible for data analysis, producing bioinformatics pipelines for use with new sequencing applications delivered on HPC platforms, maintaining and improving current pipelines, increasing automation of tasks and supporting the project management team with bioinformatics and NGS customer enquiries.This maternity cover contract is anticipated to last 12 months however it may be shorter or longer depending on when the absent employee returns to work.Earlham is a vibrant, contemporary research institute and a UK hub for innovative Bioinformatics through research, andlysis and interpretation of data sets. We host one of the largest computing facilities dedicated to life-sciences research in Europe and our aim is to ensure that biological science in the UK has access to a skill base in genomics and bioinformatics to deliver programmes leading to improved food security, advances in industrial biotechnology and improved human health and wellbeing.At Earlham we offer competitive salaries, excellent defined contribution pension scheme, life assurance, tailored learning and development and onsite sports facilities that are available to all staff and their guests. We are located within easy reach of the Norfolk Broads and coastal areas of outstanding natural beauty.For further information and details of how to apply, please visit our web site http://jobs.earlham.ac.uk/ or contact Human Resources, Norwich BioScience Institutes Partnership, Norwich Research Park, Colney, Norwich, NR4 7UH, UK, 01603 450462 quoting reference 1001883. As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy.
1038308| ECS Recruitment Group Ltd| Analytical Method Development Lead| I am currently looking for a new Analytical Method Development Expert to join the R&D team of my client's global healthcare organisation, specialising in Inhalation, based in Loughborough.Working Hours -37.5 hours per week, Monday - Friday on a permanent basis, with a competitive salary and benefits.Overall Mission*Work as part of a team responsible for the testing and development of new inhalation pharmaceutical products as part of a successful R&D organisation. *You will be responsible for leading the development of analytical methods that will be used for the testing of pharmaceutical products. *Supporting the testing of drug products with 'from scratch' methods which will have marginal or zero literature available.*The principal dosage form will be inhalation, and the main technique will be LC.*Work with clients and on new development projects on drug development.*The successful candidate will also be required to have a knowledge of organic chemistry, in order to facilitate full contribution to the development of stability indicating impurity methods.Knowledge & Compulsory requirements*Very knowledgeable in the theoretical aspects of analytical method development with particular emphasis on development of LC methods*Practical experience of the execution of method development and method validation*Knowledge of organic chemistry and experience of relating this knowledge to the prediction of degradation pathways of organic molecules.*Experienced in the validation requirements for analytical methodology in the pharmaceutical industry (MHRA/FDA/ICH etc.)*Experienced in working to GMP (good manufacturing practice) *A track record of problem solving and production of robust methodologies to analyse pharmaceutical products.*Experience of a wide range of instrumental as well as practical experience of "wet" and classical chemistry.*Proven ability to work methodically and pay meticulous attention to detail.*Experienced in the characterisation of organic impurities, with emphasis on utilising LC with mass spectrometry detection as the principal means of elucidation*Broad knowledge of current industry practices, with an established network of relevant external contacts, ideally having history of authoring relevant publications *Working knowledge of analytical method life cycle management, to include Quality by Design and method risk assessmentsQualifications*Degree qualified, MSc or PhD in Chemistry and/or Biochemistry*Extensive experience in a method development role in the pharmaceutical industry.
7124| Medical Research Council, Toxicology Unit| MRC Postdoctoral Scientist| MRC Postdoctoral Scientist Medical Research Council -Toxicology Unit, LeicesterSalary range: £30,162 - £31,099 per annum plus allowances*Fixed term for three years (funded by BBSRC)We are looking to appoint a postdoctoral scientist specialising in RNA biology and biochemical techniques to join the MicroRNA Regulation of Gene Expression Group led by Prof. Martin Bushell to work on a project to determine the mechanism by which microRNAs control gene-expression.MicroRNAs have emerged as a major mechanism of gene regulation in metazoans, controlling the expression of approximately 60% of all protein encoding genes. These non-coding RNA molecules are ~21 nucleotides in length and exert their activity by base-pairing with specific mRNAs (normally within the 3'UTR) inhibiting gene expression at the post-transcriptional level. Since their discovery, numerous studies have documented the fundamental roles of these small RNA molecules in virtually all aspects of life and disease. However, the mechanisms by which these molecules function to repress gene-expression has remained unclear and controversial. The aims of this project are to resolve and understand the mechanistic heart of the miRNA-repression apparatus, to finally understand how repression is achieved. Using a variety of biochemical approaches you will investigate the role of the helicases in miRNA-repression, the goal being to reconstitute the repressive hub and determine the role of the helicases in this process using an array of RNA-Seq experiments and molecular biology approaches.You will have been awarded (or in the final stages of obtaining) a PhD in biological sciences, have experience in RNA-Seq methodologies, cloning, western blotting, qPCR and immunoprecipitation. Experience of mammalian tissue culture, in vitro RNA synthesis, and bioinformatics would be an advantage. You will be committed to working at a highly competitive level, able to communicate scientific ideas effectively and have published (or about to publish) in a peer-reviewed journal.The Medical Research Council Toxicology Unit, located at the University of Leicester, is an internationally renowned institution delivering field-changing mechanistic insights into toxicology and disease. The Unit is equipped with state-of-the-art facilities and offers excellent opportunities for postdoctoral development. The Unit is expected to relocate to the University of Cambridge during 2019.Choosing to come to work at the MRC means that you will have access to a whole host of benefits from a final salary pension scheme and excellent holiday entitlement to access to employee shopping/travel discounts and salary sacrifice cycle to work scheme and childcare vouchers, as well as the chance to put the MRC on your CV in the future.For full details of this post and to complete an online application, visit https://mrc.tal.net/vx/lang-en-GB/appcentre-1/candidate/postings/480 and upload your CV along with a covering letter. Please quote reference TOX 439.Closing date for applications: 28 February 2017The MRC is an Equal Opportunities Employer. Final appointments will be subject to pre-employment screening.The MRC Toxicology Unit is a member of Athena Swan.* For those who have only recently completed their doctoral studies (or who may be more experienced and moving into a new research discipline or with limited experience of key transferable skills) you will be given the choice upon appointment of undertaking the MRC Post-Doctoral Training Scheme which provides you with personal allowances of £1,000 initial settlement plus an annual training allowance of £850 increasing to £1,300 in year two, and £1,800 in the third year.
1038337| Westbourne Partners Ltd| Python Developer - London - Hedge Fund| Python Developer - London - Hedge Fund I am currently hiring for a Hedge Fund in London who are looking to continue growth in their technology division after a very successful 2015 trading year. The ideal candidate will have excellent full stack Python knowledge with very strong experience with OO Python Development. Ideally you will have experience with MongoDB though any NoSQL Db would be considered. Mercurial would be a nice to have but experience with GIT or any other distributed version is acceptable. Java or C++ as a secondary skill would be nice but not a pre-requisite. The role is quite varied and will involve working very closely with the Quants and Traders. Required: BSc/MSc/PhD in a mathematical discipline or Computer Science from a top-tier University. Strong technology skills; at least three years' experience in the full development life cycle. Agile/TDD/BDD experience. Strong Python skills. Ability to work well in a small, agile team in a critical role in a fast-paced environment. A proponent of strong software engineering techniques and agile methods: continuous integration, code review, unit testing, refactoring and related approaches. Proficient working on both Linux and Windows platforms. Desirable Javascript Pandas/Numpy/SciPy Web development experience Charting libraries - Matplotlib, D3, Highcharts etc. Financial experience Familiarity with financial risk measures Statistical methods Oracle/SQL Pyramid Successful candidates will not need to come from a finance background. You will however need to come from a background where you have not be pigeon holed into a given area of Python that has restricted your breadth of knowledge. If you are interested in discussing this opportunity further please contact me at (see below) or call.
7162| BBSRC, International Relations Unit| Assistant International Programme Manager| Biotechnology and Biological Sciences Research Council (BBSRC)Assistant International Programme ManagerSalary £24,193 per annumFull time, fixed term for 8 monthsSwindon About UsThe Biotechnology and Biological Sciences Research Council (BBSRC) invests in world-class bioscience research and training on behalf of the UK public. Our aim is to further scientific knowledge, to promote economic growth, wealth and job creation and to improve quality of life in the UK and beyond. Funded by Government, and with an annual budget of around £467M (2012-2013), we support research and training in universities and strategically funded institutes. BBSRC research and the people we fund are helping society to meet major challenges, including food security, green energy and healthier, longer lives. Our investments underpin important UK economic sectors, such as farming, food, industrial biotechnology and pharmaceuticals. For more information about BBSRC, our science and our impact see: http://www.bbsrc.ac.ukAbout the RoleThis is an excellent opportunity for developing work experience, skills and career development in international activities. Working with a number of European partners, the Assistant International Programme Manager (AIPM) will support the operational delivery of the work of the International Relations Unit. This will involve supporting with projects, assisting with budget management, contribution to briefings and serving as a point of contact between the grants delivery team. You will assist with the organisation of meetings, workshops and visits to overseas countries and maintain the web pages in the International section of BBSRC’s website.Please visit our job board at http://www.topcareer.jobs/Vacancy/irc240191_6977.aspx for additional details.About YouIdeally you will have a Degree in a biology-related subject with an aptitude for administrative planning. You will have excellent writing and interpersonal skills and be able to work closely with colleagues to ensure work is delivered on time and within budget. You have an understanding of the work of BBSRC including the purpose of international collaborations and you must be able to travel in the UK and Europe for short periods.How to ApplyApplications are handled by UK Shared Business Services (UKSBS). To apply please visit our job board at http://www.topcareer.jobs/Vacancy/irc240191_6977.aspx and complete an online application. Applicants who are unable to apply online should contact us by telephone on 01793 867000. Please quote reference number IRC240191. The closing date for applications is 08 March 2017. Interviews are expected to take place on 23 March 2017.The BBSRC welcomes applications from all sections of the community, irrespective of race, ethnic origin, religion, sexual orientation, grounds of gender, disability, age, race/ethnicity, religion or philosophical belief or sexual orientation.
1038289| Michael Bailey Associates - Zurich| Risk Modeling&Analytics Specialist| For our banking client in Zürich we are currently looking Risk Modeling & Analytics Specialist:START: 01.03.17 DURATION: 17 weeks LOCATION: ZürichThe role would include:- carry out project-based independent model assessments in line with the UBS model governance policy, supplementary documents, and the IFRS9 instructions, notably - assess the model's conceptual soundness and methodology - check appropriateness of assumptions, parameters, model calibrations, qualitative or expert adjustments, etc. - review outcome, impact, or benchmark analyses and develop a benchmark model (as appropriate) - assess model risk, including model robustness analysis, identification of limitations, and their assessment - document the assessment to required standards - interact and discuss with stakeholders (model developer as well as senior model owner and model governance bodies)The ideal candidate must bring:- a Master's or PhD degree in financial mathematics/engineering, statistics, or econometrics - at least three years experience in risk modelling, model validation or related fields - familiarity with accounting standards is a plus - ability to apply quantitative techniques to solve practical problems, especially in the areas of expected loss calculation - very good communication skills and the ability to explain technical topics clearly and intuitively, both written and orally - proficient in using statistical modelling software (eg, Matlab, R, SAS, STATA) - co-operative and team-orientated, while being able to motivate and organize yourself and complete tasks independently to high quality standards - fluent in English, oral and writtenMichael Bailey International is acting as an Employment Business in relation to this vacancy.
1038336| WSI Nationwide| Data Scientist - Machine Learning, NLP| Data Scientist - Machine Learning - levels I, II, Senior or Principal DOE.Our client is working to create a seamless and frictionless health care experience for consumers nationwide. This presents a unique challenge and opportunity for innovative and disruptive solutions from the Data Office. Our Data Scientists design, develop, and implement data-driven solutions using machine learning technologies and advanced statistical analyses. You should be passionate about finding insights in data, comfortable with large and fragmented data sets, and command a variety of analytic tools at your disposal. The ideal Data Scientist candidate is an independent, solution-oriented thinker with a strong background processing large data sets, applying analytical rigor and statistical methods, and driving toward actionable insights and novel solutions. Responsibilities:- The selected Data Scientist candidate will design and develop end-to-end machine learning pipelines (data exploration, training data generation, feature engineering, model building, and performance evaluation) for a wide variety of projects. - Work in a multi-disciplined team where you'll take full ownership of turning discoveries and ideas into machine learning models. - Design, implement, and analyze online experiments, including A/A and A/B testing, in a variety of configuration environments. - Qualified Data Scientist candidates will have many of the following requirements: - Experience as a Data Scientist - End to end machine learning experience. - PhDs preferred or MA/MS - Masters with lots of experience. Minimal: a Bachelors BA/BS degree (or equivalent experience) in Computer Science, or its equivalent in a related technical field and 3 years of related work experience or equivalent combination of education and experience. Master's or PhD degree preferred. Prefer a specialization in entity resolution/disambiguation, information retrieval, machine learning, or natural language processing. - Strong analytical skills and comfortable working with large data sets and ability to transform data into actionable insights.- Exceptional technical skills: - Strong programming skills in at least one language such as Python, Java, Scala, C++, Julia - Experience with SQL and relational databases. - Experience with unstructured & semi-structured data sources and requisite processing tools.- Ability to work in an agile environment.Preferred Capabilities & Responsibilities - Passion for helping healthy people stay well and for improving the comfort and health level of sick people as efficiently and compassionately as possible. - Familiarity with retail, E-commerce, or financial analytics, including approaches such as life event modelling, customer lifetime value. - Experience in Big Data Hadoop, Spark, Storm or related paradigms and associated languages such as Pig, Hive, Mahout - Experience in AWS, Azure, or other cloud ecosystems. - Familiarity with Big Data NoSQL databases: DynomoDB, Cassandra, MongoDB, or Neo4j.- Familiarity with Elasticsearch, Soir, or Lucene.- Published work in academic conferences or industry circles. - Demonstrated ability to guide and contribute to research of new analytic approaches, inference algorithms, and machine learning techniques.- A team player attitude with excellent English verbal and written English communication skills not requiring repeating during rapid English conversation No 3rd party referrals, agencies or corp to corp sub-contracting referrals from multi-employee consulting companies, please, for any WSI requirements, no exceptions).This career opportunity is based in Portland, Oregon and offers a generous competitive starting compensation package based on experience plus up to a $30,000 signing bonus and great benefits. Your asking compensation will be submitted after your approval. They offer a very generous relocation package. When resumes are received, the candidate is contacted if there is a match, the situation is thoroughly described and the candidate tells us how they would like us to proceed. No information leaves our office without prior approval. This creates long term relationships, which we encourage. WSI is a specialty recruiting organization with over twenty years experience and fees paid by our selected client companies, freeing our hands to find top level candidates for better projects all over the USA.
7144| Science and Technology Facilities Council| Post-Doctoral Research Assistant - Laser Spectroscopy| Post-Doctoral Research Assistant - Laser SpectroscopySTFC Rutherford Appleton Laboratory, Harwell, OxfordshireSalary £37,213 - £40,014 (dependent upon qualifications and experience)Fixed Term (14 months)About UsThe Science and Technology Facilities Council (STFC) is one of Europe’s largest research organisations. We’re trusted to support, enable and undertake pioneering projects in an amazing diversity of fields. Through world-class facilities and people, we’re driving ground-breaking advances in science and technology.About The RoleWe now have an opportunity for a Post-Doctoral Research Assistant (PDRA), working for STFC’s Central Laser Facility (CLF), but based within the Research Complex (RCaH) at Harwell. The role will carry out research and development on the application of ultrafast vibrational spectroscopy and optical imaging to gain mechanistic insights into a wide range of different material systems.CLF is a world-class centre for research in physical and life sciences, housing some of the most intense lasers in the world, while RCaH is a multidisciplinary laboratory that provides facilities for researchers to undertake new and cutting edge scientific research.Responsibilities will include:• working with a team of scientists from Johnson Matthey and RCaH to develop the applications of non-linear Raman spectroscopy, infrared spectroscopy and fluorescence imaging techniques• collaborating between CLF, RCaH and Johnson Matthey in the design and performance of experiments• supporting and encouraging science programmes within CLF and the wider Harwell Campus with an emphasis on industrial applications and commercial engagement• designing and running experiments, acquisition and analysis of data and publishing and disseminating results in science journals and conferences.Some travel to conferences and stakeholder locations will be required, as well as a flexible approach to working hours when required.About YouYou will be PhD qualified with experience in laser based experimentation, scientific instrument development, and scientific writing.Any further experience in the following areas is beneficial but not essential:• instrumentation such as microscopy, UV-Vis, Fluorimeter and FTIR• chemical catalysis• use of spectroscopic techniques for science research• relevant links to Industry• LabVIEW and C++ programming.You will demonstrate excellent interpersonal and communication skills to liaise with a wide range of colleagues and stakeholders, along with a self-motivated approach and excellent organisation skills.BenefitsAn exceptional index linked pension scheme, 30 days leave allowance and flexible working are offered, as well as an onsite nursery, subsidised restaurant, gym and sports facilities. To ApplyApplicants are required to include a cover letter outlining their suitability for this role. Please also state where you saw this role advertised.Applications are handled by UK SBS; to apply please visit our job board at http://www.topcareer.jobs/Vacancy/irc239883_6957.aspx. Applicants who are unable to apply online should contact us by telephone on +44 (0)1793 867000.The closing date for applications is 5th March 2017.

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