8037| The Institute of Cancer Research, Cancer Biology| Post Doctoral Training Fellow - Cancer Biology| The Institute of Cancer Research, London, is one of the world’s most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. We provided the first convincing evidence that DNA damage is the basic cause of cancer, laying the foundation for the now universally accepted idea that cancer is a genetic disease. Today, The Institute of Cancer Research (ICR) leads the world at isolating cancer-related genes and discovering new targeted drugs for personalised cancer treatment.Under the leadership of our Chief Executive, Professor Paul Workman FRS, the ICR is ranked as the UK’s leading academic research centre. Together with our partner The Royal Marsden, we are rated in the top four cancer centres globally.The ICR is committed to attracting, developing and retaining the best minds in the world to join us in our mission – to make the discoveries that defeat cancer.The Genome Stability Team, led by Professor Jessica Downs, is investigating the interplay between epigenetics and genome stability. The goal of this research is to understand how the packaging and organisation of DNA in cells helps to maintain its integrity and prevent tumourigenesis. A Post Doctoral Training Fellow position funded by Cancer Research UK is available to investigate the contribution of chromatin dynamics to DNA damage responses and genome stability. Applicants should possess a PhD in a biological science such as cell biology or biochemistry. Experience with genetic engineering of mammalian cells, chromatin biology and/or genome instability is desirable. Appointment will be on a Fixed Term Contract for 3 years. The full salary scale for the post is in the range from £30,715 to £35,109 p.a. inclusive. Starting salary will be based on previous postdoctoral experience. Informal enquires can be made to Professor Jessica Downs at [email protected] Please do not send your application to Professor Jessica Downs, formal applications must be submitted online. To apply please submit your CV and covering letter (addressing with specific examples where you meet the person specification and incl. the names and addresses of two referees) online on ICR careers webpage (vacancy reference 517)

8036| Dublin City University, Fraunhofer Project Centre| Development of microfluidic systems for applications in medicine and the life sciences| We offer an exciting research position in [email protected] – Ireland’s first Fraunhofer Project Centre for Embedded Bioanalytical Systems at Dublin City University. In collaboration with the Fraunhofer Institute for Production Technology (IPT) in Germany, [email protected] engineers and manufactures next-generation life-science technologies for the benefit of people and societies. [email protected] operates at the challenging crossroads of microsystems engineering and the life sciences. Common fields of application are in-vitro (“Point-of-Care”) diagnostics, pharma, life-science research, agrifood and environmental monitoring.Background & Role:You will develop microfluidic designs and manufacturing processes for typically polymer-based microfluidic systems towards high technology readiness levels (TRLs) within [email protected] In this role you will have access to competent technical, infrastructural and administrative support and the opportunity to evolve a multi-facetted skillset in an environment where you closely collaborate with world-class research organisations as well as domestic and international companies. Attractive career opportunities will arise with the success of [email protected] Principal Duties and Responsibilities:You will be reporting to the [email protected] director or a manager appointed by him. Your duties will include, but are not limited to:• Development of microfluidic “Lab-on-a-Chip” systems by microfluidic design, experimental characterisation, modelling and simulation• Development of advanced manufacturing processes for high-TRL, polymer-based microfluidic “Lab-on-a-Chip” systems• Development of support instrumentation / optical detection platforms• Bioassay optimisation on microfluidic systems;• Support of project management, reporting and interactions with partners;• Support of project acquisition from industry and funding agencies;• Internal technical reporting;• Authoring of scientific publications and marketing activities;• Related administrative tasks.For covering these tasks, you can avail of [email protected]’s interdisciplinary staff competency matrix and training.Minimum Criteria:Applicants must have a PhD on a related topic; salary point according to your present postdoctoral research career. Relevant experience in the design and testing of (typically polymer) microfluidic “Lab-on-a-Chip” systems for bioanalytical testing and their manufacture as well as in bioassay optimisation is desirable.

8077| University of Calgary| Post Doctoral Fellowship to study telomere dynamics during early development| THE PROJECT. We are seeking ambitious applicants for a prestigious "Eyes High" Post Doctoral Fellowship (https://ucalgary.ca/research/eyes-high-postdoc) at the University of Calgary in Alberta, Canada. The project will involve utilizing genetic, imaging and bioinformatics tools to dissect the mechanisms of stem cell maintenance, epigenetic regulation and telomere dynamics during early development. Individuals will participate in studies that include, but are not limited to, using murine models to examine effects of assisted reproductive technologies (ART) such as intracytoplasmic sperm injection (ICSI) on measures of epigenetic state and telomere length and heterogeneity.REQUIREMENTS. A PhD and/or MD and/or DVM degree in a subject related to cell and molecular biology, developmental biology, or a related field is preferred. Applicants must have prior experience with standard technologies of stem cell and molecular biology, and experience with embryo manipulation would be particularly useful. Expertise in genome editing, differential gene expression analysis of high-throughput sequencing data or research related to developing mouse models is also highly desirable. The candidate must be self-motivated, highly independent, and have excellent theoretical and practical research skills, with strong communication, written and interpersonal skills an asset.OUR LABS AND LOCATION. The laboratories of Drs. Claudia Klein and Karl Riabowol are fully equipped for tissue culture, molecular biology and cell imaging, and the applicant will have full access to cutting edge microscopy facilities, DNA synthesis & sequencing including high-throughput services such as RNAseq, ChIPseq and others, mass spectrometry, FACS, a transgenic mouse facility including a knockout service, tissue microarray and bioinformatics services, among others. We are located in the Cumming School of Medicine and the Faculty of Veterinary Medicine within the Heritage Medical Research Building at the University of Calgary. The city of Calgary is routinely recognized as being within the top 5-10 most liveable cities in the world, boasting numerous parks, a low crime rate and hundreds of kilometers of bicycle paths and other public indoor and outdoor facilities. Calgary is situated near the Rocky Mountains and Banff National Park, adding to quality of life through outstanding recreational activities.WHAT WE OFFER. This position is supported by a University of Calgary 'Eyes High' Post Doctoral award with a two year term and the possibility of extending to a third year. The position comes with a $55,000/year stipend and all postdoctoral scholars whose initial appointment is for 12 months or longer will be eligible to receive the Alberta Health Care Insurance Plan (AHCIP). The AHCIP provides Alberta residents with coverage for hospital and physician services. Visit the AHCIP website for information on how to register and to see what hospital and physician services are provided. Additional information can be found at https://ucalgary.ca/research/postdoc/benefits or by inquiring at [email protected] The postdoctoral scholar will participate in weekly joint work-in-progress laboratory meetings, institute journal clubs and research seminars where external speakers, principal investigators, postdoctoral scholars and trainees present their most recent work. They will work in a collaborative multi-disciplinary group made up of researchers, postdoctoral scholars, research associates and coordinators, biostatisticians, bioinformaticians and trainees at all levels. We encourage trainees to present their research findings at local, national and international conferences.APPLYING. To apply interested candidates should submit a cover letter indicating how their background suits this position, their CV with the names and contact information of three references in one PDF file to Ms. Benedicta Anim Odame-Ankrah (Email [email protected]) (Tel: 1-403-220-3029).TIMELINE AND APPLICATIONS DETAILS. Applications are due by November 1, 2018. They will be evaluated and successful candidates will be contacted by November 19, to arrange interviews. Ideally the successful candidate will begin early in 2019, but starting date is negotiable.

8047| Aix Marseille Université, CNRS| Post-doctorate on studying auditory cortex plasticity| A post-doctorate positions are available immediately in the group of Dr. Arnaud Norena at Laboratory of Integrative and Adaptive Neuroscience, CNRS-Aix-Marseille University, Marseille, France.Our group is studying the auditory perception, the neural correlates of auditory perception and the plasticity of auditory centers due to specific acoustic environment or cochlear hearing loss. We have also a strong interest on computational and theoretical neuroscience (neural coding and system dynamics). The salary will be competitive.website: https://lnsc.fr/equipe/dynamique-neuronale-et-audition/We are looking for a highly motivated candidates to be involved in a project aimed at investigating the cortical plasticity triggered by cochlear hearing loss (and potentially associated to tinnitus – “the auditory phantom perception”) from multi-unit cortical recordings. In particular, we are interested in the neural coding of intensity level (from information theory point of view) in presence or absence of hearing loss. and in the mlecular mechanisms of central inhibition.We are looking for a candidate with experience in:· central electrophysiology with arrays of micro-electrodes · and/or strong background in neurophysiology, signal processing, information theory and computational neuroscience· programming skills in Matlab and/or Python are also highly desirable

8053| Luleå University of Technology, Department of Civil, Environmental and Natural Resources Engineering| Post-doctoral researchers position in urban water engineering – Sources of emerging contaminants entering urban drainage systems| Ref 2324-2018The Urban Water research group at the Department of Civil, Environmental and Natural resources engineering at Luleå University of Technology seeks a driven and committed post-doctoral researcher with focus on Characterization and management of stormwater sediments.Research groupUrban Water Engineering research at LTU covers the entire urban water system (stormwater management, water and wastewater supply) including collection, transport and treatment, as well as organisation and planning. The research aims to encourage a clean environment and the wise use of resources, while preserving the public’s health and safety. The group’s overall aim is to contribute to the development of sustainable urban water systems.The Urban Water research group has a strong position in research and education within the area of urban water systems mainly regarding stormwater, wastewater and sewer systems. Being a part of the Urban Water research group means working in an international and creative environment. The group consists of a number of senior researchers, adjunct professors and about 14 doctoral candidates. The group has an extensive international collaboration network.More information is available on www.ltu.se/waterResearch ProjectUrban areas contain numerous diffuse sources of contaminants, which are released during wet weather and discharged into urban drainage systems. Important sources of such contaminants include surfaces of buildings, structures, streets, highways, and green areas, which are exposed to wash-off processes driven by rainfall, and stormwater and snowmelt runoff. Wash-off processes that comprise both physical detachment of materials and microorganisms accumulated on surfaces as well as chemical corrosion and dissolution of materials forming such surfaces, facilitate releases of materials, chemicals (including emerging contaminants) and microbiological organisms into urban stormwater and snowmelt transported in the form of runoff. Additional chemicals may be released in storm sewers conveying stormwater. The distribution and magnitude of contaminant releases varies depending on the source characteristics, and the type, intensity and duration of the wash-off process. Besides the magnitude of contaminant releases, their partitioning into the dissolved or particulate fractions is of utmost importance for assessing the contaminant mode of transport, treatment options, and fate. In general, contaminants attached to particles follow sediment transport and are easier to separate from the liquid phase by naturally occurring settling or by filtration. For dissolved contaminants, the truly dissolved fractions are of particular interest, because they represent the most bioavailable form of chemical substances and may be precursors of chemical impacts on biota. In summary, the successful candidate for this position will focus on characterizing the urban diffuse sources and releases of contaminants through wash-off processes along urban surfaces.The Post-Doctoral researcher position is part of DRIZZLE - Centre for Stormwater Management a Research Centre of Excellence. In DRIZZLE, researchers at Luleå University of Technology, companies, and municipalities will develop pioneering, research-based stormwater management knowledge and solutions: to minimize pollution loads discharged into receiving waters; to minimize the risk for flooding in urban areas; and to exploit the beneficial opportunities that stormwater runoff can offer. DRIZZLE consists of 11 parties, i.e. Aarsleff Rörteknik AB, Stormwater&Sewers, Järven Ecotech AB, Luleå Municipality, Luleå University of Technology (project manager), NCC Infrastructure, Rent Dagvatten AB, Stockholm City, Stockholm Water, Tyréns and StormTac AB.DutiesThe work will contain laboratory and field work which is planned and performed by the post-doctoral researcher in collaboration with other staff at LTU. The results will be presented in scientific articles Participating and presenting the work at national and international conferences and for national stakeholders are important duties. Administration and/or teaching activities will be added.QualificationsWe seek a candidate with a doctoral degree in civil, water resources or environmental engineering or related disciplines. Experience conducting field experiments on stormwater control measures and the knowledge of measuring equipment, stormwater sampling, relevant scientific/analytical methods, (geo-)chemistry and hydrological modelling and/or statistics are required. Other skills needed are the ability to work independently and/or within collaborative teams as well as being able to penetrate new research areas.English language skills are required since the research will be conducted in international collaboration and the results will be presented internationally in scientific journals and at conferences. Swedish language skills are beneficial since the work will be carried out in collaboration with Swedish municipalities and industry. Having a professional network among Swedish municipal staff and/or the international scientific stormwater research community will be beneficial.Similar applies for a driving license is required to access to field sites. The applicant must upon request be prepared to give contact information of two references.Information For further information about the position, please contact: Professor Maria Viklander, +46 70 330 14 86, [email protected] representatives: SACO-S Christer Gardelli, +46 (0)920-49 1809 [email protected] and OFR-S Lars Frisk, +46 (0)920-49 1792 [email protected]å University of Technology is actively working on equality and diversity that contributes to a creative study- and work environment. The University's core values are based on respect, trust, openness and responsibility.In case of different interpretations of the English and Swedish versions of this announcement, the Swedish version takes precedence.The post-doctoral researcher will have a time-limited employment for 2 years.ApplicationWe prefer that you apply for this position by clicking on the apply button below. The application should include a CV, personal letter and copies of verified diplomas from high school and universities. Your application, including diplomas, must be written in English or Swedish. Mark your application with the reference number below.Reference number: 2324-2018Deadline for application: 2018-09-24

8059| University of Cambridge, Department of Physics| Winton Advanced Research Fellowships (Group Leaders) in the Physics of Sustainability| £39,992-£50,618Department of PhysicsREFERENCE: KA16494The Winton Advanced Research Fellowship scheme supports outstanding, scientists, providing generous support packages comparable to those for Assistant Professor positions to enable Fellows to establish and lead their own independent research group. We are looking for candidates with new ambitious programmes that expand the range of research activities within the Cavendish Laboratory, and welcome proposals that cross traditional boundaries between physics and other sciences and engineering disciplines.Candidates are expected to be of the calibre that would be competitive for schemes such as the Royal Society University Research Fellowship (URF), European Research Council (ERC) Starter grants and Assistant Professorship positions across the world. Fellows are expected to win permanent posts in universities at the end of their fellowships. A list of the current Fellows and details of their broad range of research interests can be found at http://www.winton.phy.cam.ac.uk/directory/fellows.Fellows will have access to state-of-the-art laboratory space and facilities in the existing and the new Cavendish Laboratory (http://www.phy.cam.ac.uk/caviii) that will be operational in 2021/22. Much of the research of the Programme is also based in the Maxwell Centre (http://www.maxwell.cam.ac.uk) that is home to interdisciplinary research on the West Cambridge Science and Technology Campus. The Centre includes research facilities as part of the Henry Royce Institute and office space to foster collaborative research including engaging with industrial partners.The Fund Managers of the Winton Programme invite applications for up to two Group Leaders - Advanced Research Fellows. Candidates will normally have completed at least one post-doctoral appointment at an institution different to that at which their PhD was obtained. Fellowships will be of 5 years' duration and will provide salary comparable to junior university faculty positions (on the scale currently £39,992-£50,618 per annum) with start-up packages sufficient to enable new groups to be established. Funding is available for:Small and large equipment to enable new research directions to be startedLaboratory and computing facility set up costs and on-going operating expenses including access chargesFull funding for a graduate student with additional studentships available through Departmental allocations, Doctoral Training Centres and various Cambridge Scholarship schemesLaboratory and office space for Fellow and their group membersTravel budget to build international collaborations and attend conferencesProposed projects should be in new areas or take new approaches in established areas related to research in the broad field of the application of physics to sustainability.Applicants should submit curriculum vitae including a list of publications and the names and addresses of 3 referees; a personal statement of accomplishments to date (up to 1000 words); an outline research proposal (up to 1500 words) with a brief account of research support required (up to 750 words). The research outline should emphasise the novelty of the research approach, but also set out a clear plan of activity.Those successful at the outline stage will be invited for an interview for which guidance will be provided.Fixed-term: The funds for this post are available for 5 years in the first instance.To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.Details of the Winton Programme can be found at http://www.winton.phy.cam.ac.uk/ and enquires and further information can be obtained by contacting the Winton Programme manager Dr Nalin Patel ([email protected]).Please quote reference KA16494 on your application and in any correspondence about this vacancy.CLOSING DATE: 17 October 2018The University values diversity and is committed to equality of opportunity.The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

8051| Kings College London, Department of Imaging Chemistry and Biology| Postdoctoral Research Associate in Cancer Imaging| The salary will be paid at Grade 6, £37,412 to £44,105 per annum, inclusive of £3,223 per annum London Allowance.We are seeking a Postdoctoral Research Associate with experience in cancer biology to work in the Molecular Imaging Lab in the Department of Imaging Chemistry and Biology (www.witneylab.com). The successful candidate will provide in vitro and in vivo biological expertise as a member of a multidisciplinary team comprising molecular biologists, chemists, and physicists, to help develop novel fluorine-18 labelled positron emission tomography (PET) radiotracers to image cancer drug resistance. In collaboration with the new GMP radiochemistry facility at KCL (the PERL), we will seek to translate these novel imaging methods to the clinic.The post holder will plan and conduct a high quality programme of research in the biological evaluation of novel radiotracers for cancer imaging. This is an exciting opportunity to join a vibrant multidisciplinary research group within one of the premier biomedical imaging centres in Europe, where you will enjoy support in career development through Fellowship applications, networking events, and attendance at international conferences.This post will be offered on a fixed-term contract for 2 years.This is a full-time post.The selection process will include a panel interview and a presentation.For an informal discussion to find out more about the role, please contact Dr Tim Witney at [email protected] apply, please visit https://my.corehr.com/pls/kingrecruit/erq_jobspec_version_4.jobspec?p_id=003804 and register with the King’s College London application portal and complete your application online.Closing date: 7 October 2018

8073| Ghent University, Mechanics of Materials and Structures| Postdoctoral vacancy (36 months) on patient-specific design and finite element modelling of 3D printed medical implants| 3D printing or Additive Manufacturing (AM) technologies carry the promise of revolutionizing the quality and efficiency of healthcare. However, the required technologies, even when available, are currently too fragmented to be integrated into routine, affordable and streamlined solutions that can benefit a large number of patients. The challenge thereby is to deliver 3D printing technologies that enable:Patient-specific solutions: personalized medical devices that are designed using the images acquired for individual patients and best fit their treatment needs;Complexity and miniaturization: complex shapes, articulations and miniaturized geometries of implantable medical devices and instruments have the potential to radically enhance treatment effectiveness and post-treatment recovery;Streamlined care: the ability to integrate diagnosis, design and manufacturing of AM medical devices into a validated software platform is the key to delivering fast, affordable treatments with dramatic life-saving potential.The INTERREG project 3DMed aims to improve affordability and large-scale accessibility of medical treatment using 3D printed devices. This will be achieved by increasing the Technology Readiness Level (TRL) of state-of-the-art 3D printing technologies for medical applications and integrating them into a streamlined, fast, cost-effective software platform for use in routine clinical practice. This project contains 17 partners from The Netherlands, Belgium, France and United Kingdom, including universities, hospitals, software suppliers, 3D printing companies, clinical observers, manufacturers of medical devices and implants,... The project is coordinated by TUDelft.In this Postdoctoral position, it is the purpose to develop patient-specific design and finite element modelling of 3D printed medical implants. This position requires an in-depth knowledge of advanced design, finite element modelling and topology optimization, based on the processing and segmentation of patient-specific medical images. Important criteria that will be investigated, are: (i) stress limits for a fatigue-safe design (under multi-axial loading); (ii) critical stress concentrations due to certain geometrical discontinuities; (iii) stiffness match (or mismatch) with surrounding body parts; (iv) thermal behaviour of the part at body temperature. Different orthotics and prosthetics will be covered and a close collaboration will be required with the researchers at TUDelft, clinical observers, AM service providers and software companies.Only candidates with a PhD degree or equivalent experience should apply. The candidate should have a strong background in design and FE modelling for medical applications. He/she will closely work together with the other postdoc in the team (see other vacancy) and is willing to travel frequently to meet and discuss with the other project partners in the neighbouring countries.More information can be found on:http://www.composites.ugent.be/PhD_job_vacancies_PhD_job_positions_composites.html

8024| UKRI Medical Research Council, Laboratory of Molecular Biology| Postdoctoral Scientist - Neurobiology - Dr William Schafer - LMB 909| Postdoctoral Scientist – Neurobiology Starting Salary £30,464 to £33,305 per annum 3 Years Fixed TermMRC Laboratory of Molecular Biology, Cambridge, UKThe MRC Laboratory of Molecular Biology is one of the birthplaces of molecular biology and is an internationally renowned centre for fundamental biomedical research. The LMB has a strong track record in training Postdoctoral Fellows who have gone on to become leading Scientists. We also have an excellent record of innovative basic research leading to applications in medicine. Scientists are drawn to the LMB from all over the world, thus creating a lively and international community for the exchange of ideas and technical innovation. Following our move to a new laboratory in 2013, we are able to provide state-of-the-art facilities in which innovative medical research, translation and collaboration can flourish.Applications are invited for a postdoctoral scientist position in the laboratory of Dr William Schafer at the MRC LMB, Cambridge to work within a programme aimed at understanding the molecular and cellular mechanisms of arousal and modulation of nociception by neuropeptides. Specifically, the post holder will carry out genetic, behavioural and molecular analyses of the receptors, neuropeptides and signaling molecules that underlie sensitisation in response to aversive sensory stimuli. Key approaches will include classical genetic analysis, generation of transgenic nematodes, and in vivo fluorescence microscopy.The ideal candidate will have a PhD in a relevant subject and possess a background in C. elegans molecular genetics and combination of skills in molecular cloning and in vivo neuroimaging.Successful applicants will be awarded a 3-year Career Development Fellowship/MRC Postdoctoral Training Scheme. The fellowship is a training and development position for a post-doctoral scientist who has recently completed their doctoral studies, or is moving into a new research discipline.The MRC Laboratory of Molecular Biology is a research institute within UK Research and Innovation (UKRI). UKRI is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at www.ukri.org.Working for UKRI MRC provides a whole host of benefits including a defined benefit pension scheme, excellent holiday entitlement (40 ½ days including bank holidays and privilege days) and Benenden Healthcare membership. You will also have access to employee shopping/travel discounts, on site sport and social facilities, as well as salary sacrifice cycle to work schemes and childcare vouchers.Closing date: 23rd September 2018 Final appointments will be subject to a pre-employment screening.The Medical Research Council is an Equal Opportunities Employer who participates in the Disability Confident scheme.

8056| Agri-Food and Biosciences Institute Northern Ireland (AFBI)| Senior Economist| REF: IRC233217SALARY: £36,812 - £40,473DEPARTMENT: Agri-Food and Biosciences Institute Northern Ireland (AFBI)LOCATION: AFBI Newforge, BelfastFurther appointments may be made from this competition should AFBI positions become vacant which have similar duties and responsibilities.For more detailed information and to apply, please go to www.nicsrecruitment.org.ukAlternatively, an application pack can be requested by contacting:HRConnect, PO Box 1089, The Metro Building, 6-9 Donegall Square South, Belfast, BT1 9EW. Telephone: 0800 1 300 330. Email: [email protected] requests must include your name, address and reference number IRC233217Completed application forms must be returned to arrive not later than 12:00 noon (UK time) on Monday 8th October 2018.AFBI is an Equal Opportunities EmployerApplications are particularly welcomed from Roman Catholics and Females as these groups are currently under-represented within AFBI.ALL APPLICATIONS FOR EMPLOYMENT ARE CONSIDERED STRICTLY ON THE BASIS OF MERIT

8045| Trinity College Dublin, School of Physics| Postdoctoral Researcher| Two-year Postdoctoral Research Position in Design and Modelling of Chemical and Physical Processes for the upgrading of Lignocellulosic BiomassSalary of €40,259 – €47,728 per annum (22-24 months). A position is available in the research team of Prof. Stephen Dooley at the School of Physics Trinity College Dublin, in collaboration with the School of Chemical Sciences at the University of Limerick, Ireland, supported by the Sustainable Energy Authority of Ireland. The project focusses on developing and understanding effective physics and chemistry which can convert lignocellulosic biomass into valuable chemicals and advanced liquid biofuels. The position supports multiple projects that combine experimental and computational sciences: (i) Researchers at Trinity College Dublin and the University of Limerick have invented a novel cost effective process to produce drop-in diesel and gasoline liquid transportation fuels from sustainable carbon neutral biomass. The researcher will gather crucial fundamental chemical engineering data that will lead to a full technico-economic analysis of this process. A host of experimental methods are to be applied to achieve this end. Simultaneously the mechanism and theory of the process will be probed by the application of chemical and numerical modelling procedures.(ii) In parallel associated work the researcher will take charge of a recent €3.1 million Research Infrastructure Grant that has commissioned a "Test-bed for Sustainable Chemical Processes". The test-bed provides a range of chemical reactor technologies and chemical and physical analytic equipment to probe the mechanism and element/energy efficiency of prototype technologies. The test-bed is the perfect tool to support the combination of experiment and theory to develop predictive numerical models of process chemistry.The successful candidate is expected to; lead the execution of these and other test-bed projects and their reporting in international peer reviewed journals in the energy/physics/chemistry/chemical engineering area, to publicise their progress at international scientific conferences, and to engage with external collaborators industry and academic collaborators. A formal background in the physical sciences, holding a Ph.D. degree in any physical sciences discipline such as Chemical Engineering, Material Science, Physical/Organic Chemistry, Catalysis, Computational Modelling or a related subject matter would be most appropriate.Experience of chemical reactor technology, purification protocols, chemical reaction kinetics, thermophysical modelling, and of chemical analysis techniques is required. Experience with chromatography and mass spectrometry are particularly important. Knowledge of scaling chemical reactions toward chemical engineering setups would be helpful, as would knowledge of sophisticated spectroscopic techniques such as liquid phase H1 and C13 Nuclear Magnetic Resonance (NMR) spectroscopy. Skills and/or interest in translating experimental findings into numerical models is viewed as a critical commodity. The successful applicant will join a dynamic inter-disciplinary team of experimental and computational scientists and engineers, and will therefore have the opportunity to develop new skills and experiences.Prospective candidates should send a two page CV, a covering letter outlining their educational background, research track-record, interest in the position and the names and contact details of two referees to Prof. Stephen Dooley ([email protected]). Please quote the entire job title in the subject line of your email. The 24-month position is available immediately. Applications will be evaluated as received and candidates of all levels of experience possessing appropriate skillsets will be considered. The School of Physics, Trinity College Dublin has been awarded Institute of Physics Juno Practitioner and Athena SWAN Bronze Award status for taking action to address gender inequities across its student and staff body. It is committed to promoting better working practices for men and women. See https://www.tcd.ie/Physics/womeninphysics/. The School welcomes applications from all qualified applicants, and applications are particularly encouraged from traditionally under-represented groups in Physics.

8069| Ghent University, Mechanics of Materials and Structures| Postdoctoral vacancy (3 years) on high-frequency vibration techniques for non-destructive inspection of 3D printed metal parts| The use of 3D printed metal structures is taking a very fast ramp-up in industry. General Electric has demonstrated the possibility of printing titanium fuel injectors for their LEAP engine, EADS has printed a nacelle hinge bracket for the Airbus A320, Boeing is printing plastic inlet ducts for high-altitude aircrafts, hip implants and other prosthetics are exploiting the design freedom of additive manufacturing (AM),...Additive manufacturing of titanium alloys yields great potential for the aerospace industry (and others) as it allows the generation of geometrically complex structures with high specific strength, low density and high corrosion resistance. However the inspection of such 3D printed components is almost impossible with traditional Non-Destructive Testing (NDT) techniques because of the typical complex geometries and internal cavities. A very interesting alternative is PCRT (Process Compensated Resonance Testing), a high-frequency vibration technique that tries to detect defects by isolating very small shifts in the resonance spectrum at very high frequencies.In this Postdoctoral position, it is the purpose to build a PCRT set-up for inspecting 3D printed metal parts with complex geometry, to implement the data-acquisition and to develop advanced post-processing tools for identification of defects in the frequency domain. The research is in close collaboration with Materialise and Siemens, two leading companies in the development of 3D printing. The project is funded by SIM-Flanders (Strategic Initiative Materials in Flanders).Only candidates with a PhD degree or equivalent experience should apply. The candidate should have a strong background in vibration techniques and data analysis in frequency domain.More information can be found on :http://www.composites.ugent.be/PhD_job_vacancies_PhD_job_positions_composites.html

8029| Duke University, Medicine / Pharmacology and Cancer Biology| Postdoctoral Associate Position in Tumor Immunology/Immunotherapy at the Duke Cancer Institute| The Hanks Lab is a basic/translational research lab in the Duke Cancer Institute with an interest in understanding cancer immune evasion and immunotherapy resistance. We are seeking a motivated, hardworking Post-Doctoral Candidate with a background in immunology to take a leadership role in projects focused on understanding the role of the tumor microenvironment on immunotherapy resistance in the gastrointestinal cancers. This will be a two-year minimum position. The candidate will be expected to work independently but capable of collaborating with other lab members in a team-oriented work environment. Recent Ph.D. graduates preferred. http://www.thehankslab.com- PhD degree with a background in tumor immunology- Significant experience in multi-parameter flow cytometry and in the design of cell-based assays- Significant experience working with murine cancer models- Previous grant writing experience preferred.- Background in metabolism research preferred.- Excellent verbal and written communication skills in English with outstanding organizational and analytical abilitiesInterested candidates should send CVs to Dr. Brent A. Hanks at [email protected] for consideration. Select candidates will undergo a phone interview and finalists will be interviewed in-person at Duke University.

8043| D. E. Shaw Research| Postdoctoral Fellowships in Computational Chemistry and Physics at D. E. Shaw Research| D. E. Shaw Research is seeking postdoctoral fellows of exceptional ability to join our New York–based team. This is a unique opportunity to develop and work with transformative technology in a dynamic, interdisciplinary environment. Candidates should have expertise in computational, theoretical, or quantum chemistry, theoretical chemical physics, applied mathematics, or in a relevant area of computer science. Relevant areas of experience might include force field improvement through detailed comparisons of simulation data with NMR measurements or other experimental data, development and implementation of new methodology, such as integrators or efficient approximations of long-range forces, methods for enhanced sampling or free-energy calculations, or tools to efficiently analyze large simulation datasets. Specific knowledge of any of these areas is less critical, however, than outstanding intellectual ability, unusually strong research skills, and a history of innovation and accomplishment. We are committed to fostering a stimulating, rewarding, and flexible work environment, and we offer above-market compensation to candidates of truly exceptional ability.To submit an application, please use the link provided below: http://www.deshawresearch.com/recruit/jobs/Ads/FindAPostDoc/ChemPF-MD. E. Shaw Research is an independent research group that is pursuing an ambitious, long-term strategy aimed at fundamentally transforming the process of drug discovery. We have developed a special-purpose supercomputer, ANTON®, capable of executing molecular dynamics (MD) simulations orders of magnitude faster than was previously possible. Our current projects include investigations of proteins and other biomedically relevant macromolecules as well as the development of computational chemistry methods to enable more accurate and effective MD simulations.D. E. Shaw Research is an equal opportunity employer, dedicated to the goal of building a diverse workforce. We welcome inquiries from all exceptionally well-qualified applicants, regardless of race, color, gender, age, religion, national origin, sexual orientation, gender identity, disability, pregnancy, marital status, military service eligibility, veteran status, or status in any other category protected by law.

8039| University of Vienna, Institute of Biological Chemistry| Postdoc - Pharmacologist| A talented postdoctoral fellow with strong experience in pharmacology, molecular biology, and chemical biology is sought to join the Neuropeptide Research Group at the Institute of Biological Chemistry at the University of Vienna. The group is focused on the exploration of nature's biodiversity to develop molecular probes and discover novel therapeutic leads with applications in pain, cancer, autism, gastrointestinal disorders and neurodegenerative diseases. The successful applicant will be responsible for drug target discovery and validation, pharmacological characterisation of molecular probes and therapeutic leads, ADMET and other preclinical studies.DutiesDuties and responsibilities include, but are not limited to:Research Duties• Pharmacological and biophysical characterisation of peptide ligands• Structure-activity relationship studies of molecular probes and therapeutic leads• Gastrointestinal wound healing assays and target receptor discovery• ADMET studies• Preparation of research reports, manuscripts for publications and oral presentations• Supervision and training of students and staff• Liaising with team members to promote the achievement of immediate project goalsAdministrative Duties• Support with administrative tasks, teaching and grant applications• Participation at research meetings and maintenance of an accurate lab book• Chemical purchases and equipment maintenance• Any other duties as reasonably directed by your supervisor Organisational RelationshipsThe position reports to A/Prof. Markus Muttenthaler. SELECTION CRITERIAEssential• PhD in the area of pharmacology, chemical or molecular biology, or biochemistry• Strong experience with pharmacological bioassays and analysis• Strong experience with molecular biology techniques• Well-developed laboratory and problem-solving skills• Ability to work collaboratively with colleagues and across disciplines• Ability to independently drive research projects to completion• Ability to write research manuscripts and grant/fellowship applications• Excellent written and verbal communication skills in EnglishDesirable• Experience in GPCR pharmacology (IP-1, cAMP, binding, BRET, FLIPR assays)• Experience with recombinant expression systems for peptide/protein production• Experience with bioactive peptides, peptide NMR, mass spectrometry• Experience with wound healing and/or IncuCyte instrument• Experience with animal models (i.e. DSS, TNBS models)• Experience with phage display• Ability to supervise students and junior staff• Written and verbal communication skills in German

8066| Liverpool School of Tropical Medicine| Research Assistant/ Post Doctoral Research Associate| Founded in 1898 and the oldest of its kind in the world, the Liverpool School of Tropical Medicine (LSTM) is an internationally recognised centre of excellence for teaching and research in tropical diseases. Through the creation of effective links with governments, NGOs, private organisations and global institutions and by responding to the health needs of communities, LSTM aims to promote improved health, particularly for people of the less developed/resource poorest countries in the tropics and sub-tropics.The Health Systems & Workforce Strengthening Unit within the International Public Health Department at LSTM, works to strengthen health systems and the health workforce for equitable access to quality health care, focussing particularly on health systems research and its use in guiding policy and programming to strengthen health systems and improve care. Presently, we are leading ‘PERFORM2Scale’, a 5-year multi-partner EC-funded project to scale up a process of strengthening district-level management to support workforce performance improvement; and have led the ‘ReBUILD’ consortium on strengthening health systems in conflict and crisis affected contexts and have plans to continue this work. We are presently recruiting a Research Assistant (RA) or Post-Doctoral Research Associate (PDRA), to support the Unit by helping the team to generate new work and deliver effectively on current projects. As part of the Health Systems and Workforce Strengthening Unit, you will liaise closely with researchers and international partners, to carry out and disseminate policy-relevant research in health systems in mid and low-income countries. You will provide technical input to partners in primary and secondary data management, publish research findings in peer reviewed academic journals and assist with grant proposals on health systems and human resources for health research.To be successful, you must possess a PhD (for PDRA) or Masters (for RA) in health or health-related social science discipline including a research skills component. An additional qualification or module studied related to health systems and /or human resource management will be an added advantage to your application. Proven experience in designing research, applying for ethical approval, carrying out data collection field work and analysis of data sets in low and middle-income countries is essential. Applied research skills relevant to health or health-related social science, coupled with excellent skills for producing academic products and computing skills for quantitative and qualitative data analysis are vital to the post.Closing Date: 30th September 2018Take a look at some of the great work we have achieved over the past year 2016-2017 by viewing our annual report: http://www.lstmed.ac.uk/about/publications/lstm-annual-report-2016-2017 This job is unlikely to attract a Tier 2 Certificate of Sponsorship (formerly a work permit). Applications from candidates who require Tier 2 immigration status to work in the UK may not be considered if there are a sufficient number of other suitable candidates. To apply for a Tier 2 Certificate of Sponsorship, employers need to demonstrate that they are unable to recruit a resident worker before recruiting an individual overseas. For further information, please visit: https://www.gov.uk/government/organisations/uk-visas-and-immigrationWe believe that this post will not be suitable for individuals on Tier 5 visas as these posts are not considered to be supernumerary to the organisation. For further details, please visit the UKVI website: https://www.gov.uk/browse/visas-immigration/work-visas LSTM actively promotes Equal Opportunities and Safeguarding Policies

8055| The Institute of Public Health in Ireland (IPH)| Public Health Development Officer (Policy)| The Institute of Public Health in Ireland (IPH) promotes cooperation for public health on the island of Ireland.IPH intends to recruit a Public Health Policy Officer (Policy) who will contribute to improving population health and reduce health inequalities across the island.The position will involve:• Working as part of an all-island policy team.• Supporting policy design and development processes such as evidence-review, knowledge translation and stakeholder engagement.• Delivering effective policy reviews and evaluations.• Delivering quantitative, qualitative and mixed method research projects relevant to policy issues.• Support effective co-operation on the design, delivery and review of public health policies and programmes on the island of Ireland.• Working collaboratively on public health priorities with policy stakeholders on a North/South basis, across the UK and at European level.Terms & Conditions• This post is being offered on a full-time, permanent basis • Salary scale attached to the position is €50,175- €63,974 • Location: Vistatec House, 700 South Circular Road, Dublin 8.Applications• The job description, including the essential requirements for applicants, is available here.• Applications will only be deemed valid where they include a fully completed application form. CVs will not be accepted.• Applicants must send their completed application form by 5pm on Monday 24th September 2018.• Short-listed candidates will be invited to a practical assessment relating to this post. The assessment will be held on Thursday 4th October 2018.• Successful candidates will then be invited to interview. Interviews are expected to be held between Monday 15th October and Friday 19th October 2018.8.• For any queries relating to this post, please contact [email protected]

8052| Luleå University of Technology, Department of Civil, Environmental and Natural Resources Engineering| Post-doctoral research position in urban water engineering - characterisation and management of stormwater sediments| Ref 2314-2018The Urban Water research group at the Department of Civil, Environmental and Natural resources engineering at Luleå University of Technology seeks a driven and committed post-doctoral researcher with focus on Characterization and management of stormwater sediments.Research GroupUrban Water Engineering research at LTU covers the entire urban water system (stormwater management, water and wastewater supply) including collection, transport and treatment, as well as organisation and planning. The research aims to encourage a clean environment and the wise use of resources, while preserving the public’s health and safety. The group’s overall aim is to contribute to the development of sustainable urban water systems.The Urban Water research group has a strong position in research and education within the area of urban water systems mainly regarding stormwater, wastewater and sewer systems. Being a part of the Urban Water research group means working in an international and creative environment. The group consists of a number of senior researchers, adjunct professors and about 14 doctoral candidates. The group has an extensive international collaboration network.More information is available on www.ltu.se/waterResearch ProjectStormwater control measures (SCM) have rapidly evolved and in order to maintain or upgrade their functions, they require attention with respect to maintenance and restoration of their design status, and examination of opportunities for upgrading taking advantage of the latest knowledge of this field. Two of the most common SCMs in Sweden are the gully pots and stormwater management ponds. Gully pots are located in road gutters, close to the source of runoff and hence represent near-the-source controls. They do not affect much runoff flow rates, but can be effective in trapping road surface sediments with attached pollutants. Such effectiveness has been examined in recent years with introduction of innovative designs, including various gully pot inserts enhancing sediment/pollutant capture, but also increasing maintenance costs. Stormwater ponds are typically located in the downstream parts of the drainage system and provide a broad spectrum of hydrological, water quality and ecological services and amenities. Older facilities may not reflect the latest knowledge in this field and be somewhat “dated”. The objective of this project task is to develop the knowledge of processes affecting the functionality and performance of the urban drainage system, and examine opportunities for functional upgrading.The Post-Doctoral researcher position is part of DRIZZLE - Centre for Stormwater Management a Research Centre of Excellence. In DRIZZLE, researchers at Luleå University of Technology, companies, and municipalities will develop pioneering, research-based stormwater management knowledge and solutions: to minimize pollution loads discharged into receiving waters; to minimize the risk for flooding in urban areas; and to exploit the beneficial opportunities that stormwater runoff can offer. DRIZZLE consists of 11 parties, i.e. Aarsleff Rörteknik AB, Stormwater&Sewers, Järven Ecotech AB, Luleå Municipality, Luleå University of Technology (project manager), NCC Infrastructure, Rent Dagvatten AB, Stockholm City, Stockholm Water, Tyréns and StormTac AB.DutiesThe work will contain laboratory and field work which is planned and performed by the post-doctoral researcher in collaboration with other staff at LTU. The results will be presented in scientific articles Participating and presenting the work at national and international conferences and for national stakeholders are important duties. Administration and/or teaching activities will be added.QualificationsWe seek a candidate with a doctoral degree, not older than 3 years, in civil, water or environmental engineering or related disciplines. Experience conducting field experiments on stormwater control measures and knowledge of measurement equipment, stormwater sampling, relevant scientific/analytical methods, (geo-)chemistry and/or statistics are required. Other skills needed are the ability to work independently and within collaborative teams as well as being able to penetrate new research areas.English language skills are required since the research will be conducted in international collaboration and the results will be presented internationally in scientific journals and at conferences. Swedish language skills are beneficial since the work will be carried out in collaboration with Swedish municipalities and industry. Having a network among Swedish municipalities and/or the international scientific stormwater research community is beneficial. Similar applies for a driving license that is required to access to field sites.Applicants must upon request be prepared to give contact information of two references.InformationThe post-doctoral researcher will have a time-limited employment for 2 years.For further information, please contact: Professor Maria Viklander, +46 70 330 14 86, [email protected] representatives:SACO-S Christer Gardelli, +46 (0)920-49 1809 [email protected] and OFR-S Lars Frisk, +46 (0)920-49 1792 [email protected] prefer that you apply for this position by clicking on the apply button below. The application should include a CV, personal letter and copies of verified diplomas from high school and universities. Your application, including diplomas, must be written in English or Swedish. Mark your application with the reference number below.Application deadline: 2018-09-24Reference number: 2314-2018

8075| NORCE - Norwegian Research Centre AS| Open position as Post-Doctoral Fellow at Norwegian Research Centre AS – NORCE positioned in Grimstad| Agderforskning AS, Christian Michelsen Research AS, International Research Institute of Stavanger AS, Teknova AS and Uni Research AS are merging into the new research institute NORCE Norwegian Research Centre AS this autumn.NORCE will be one of Norway's largest independent research institutes, with 700 employees, 1 500 projects, an annual turnover of approx NOK 900 million, and some 500 scientific publications per year. If we include NORCE's subsidiaries, the group has 800 employees from around the world. The group's knowledge is represented in several countries, and its turnover is over NOK 1 billion.We deliver research and innovation in energy, health, climate, environment, society and technology. Our solutions address key challenges for society and contribute to value creation on the local, national and global levels.All employees are transferred to the new company. In this way, the professional expertise and focus areas will remain the same. NORCE's main office is in Bergen, and the group has a strong presence in Haugesund, Stavanger, Kristiansand, Grimstad and Oslo.NORCE is owned by the University of Bergen, Stavanger Research Holding AS (owned by the Rogalandsforskning Foundation and the University of Stavanger), Agder Research Holding AS (owned by the University of Agder et al.) and other researchers in research and business with smaller ownersRead more about NORCE at norceresearch.no . Follow us at Facebook, Twitter, LinkedIn and InstagramOpen position as Post-Doctoral Fellow at Norwegian Research Centre AS – NORCEpositioned in GrimstadJob Summary and Responsibilities:This Post-Doctoral position is available 1 January 2019 to conduct research related to condition monitoring of hydraulic cylinders. The focus of this Post-Doctoral position will be to develop model-based condition monitoring methods to estimate the level of aeration, oxidation, leakage, water content and particle contamination in cylinders. These estimates shall then be combined by using a nonlinear particle filter to provide the end user with a prediction of the cylinder remaining useful life.The work will require: extensive utilization of sensors and instruments (such as acoustic, vibration, magnetic, etc.) to capture signals emitted from cylinders under testing, extensive post processing of data using signal processing, data fusion, statistics and particle filtersIn addition to conducting experiments, the duties of the Post-Doctoral position will include reading and knowing the relevant literature, attending and presenting at scientific meetings, and writing drafts of manuscripts. The successful candidate will be required to work in collaboration with other researchers in and outside the lab as well as travel when required. Minimum Requirements: • Ph.D. graduate within the last two years• Submit a curriculum vitae and the contact information of three references,• Experience in the fields of condition-based maintenance, instrumentation, statistics, signal processing • Publications in the fields of condition-based maintenance, instrumentation, statistics, signal processing• Knowledge of routine computational skills used for data analysis and presentation, including but not limited to Microsoft Office, MatLab. • Applicants without a PhD thesis written and defended in English must document their English proficiency through one of the following tests with the stated results or better:TOEFL - Test of English as a Foreign Language with a minimum score of 550 on the Paper-based Test (PBT), or 80 on the Internet based Test (iBT)IELTS - International English Language Testing System, with a result of at least 6.5.We offer:• Salary depending on qualifications within the range NOK 517.700 – 579.300• Benefits: includes health care coverage, business travel insurance, pension plan etc.• Twenty-four (24) month time limited appointment with NORCE• Start date: 1 January 2019• Location: Grimstad, NorwayHow to apply:Please send your application attached the required documentation to [email protected], labeled “Postdoc CM”.Submit a curriculum vitae and the contact information of three references.For full consideration applications must be received by 1 November 2018. For further information please contact Dr. Thomas J.J. Meyer, [email protected] Opportunity StatementNORCE is an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity or national origin. Women, minorities and individuals with disabilities are encouraged to apply.

8070| Ghent University, Mechanics of Materials and Structures| Postdoctoral vacancy (2.5 years) on multi-axial fatigue modelling and testing for 3D printed metal parts| The use of 3D printed metal structures is taking a very fast ramp-up in industry. General Electric has demonstrated the possibility of printing titanium fuel injectors for their LEAP engine, EADS has printed a nacelle hinge bracket for the Airbus A320, Boeing is printing plastic inlet ducts for high-altitude aircrafts, hip implants and other prosthetics are exploiting the design freedom of additive manufacturing (AM),...Additive manufacturing of titanium and inconel superalloys yields great potential for the aerospace industry (and others) as it allows the generation of geometrically complex structures with high specific strength, low density and high corrosion and creep resistance at high temperatures. However the fatigue life prediction of such components cannot be done with traditional fatigue models for traditionally manufactured metals, because the fatigue life is influenced by various factors that are specific for 3D printing: process parameters, induced voids and defects, microstructure, surface roughness, etc.In this Postdoctoral position, it is the purpose to develop suitable criteria for fatigue life prediction under multi-axial stress states, and validate them by multi-axial fatigue tests. Those criteria will be implemented in an already developed software environment. The researcher will work in close collaboration with Siemens Industry Software for this project, and will be supported by their development team. The final objective is to develop an industrial software solution that can be applied to complex AM components and predict their fatigue life. The position is a mix of numerical simulation and experimental testing in the field of multi-axial fatigue of 3D printed metals. The candidate should be experience in both aspects of the work. The equipment for the multi-axial fatigue testing is available in the lab of the research group, together with all instrumentation methods.Only candidates with a PhD degree or equivalent experience should apply. The candidate should have a strong background in fatigue life prediction for metals (e.g. critical plane approaches) and have experimental experience with fatigue testing. Experience in simulation of AM metals is recommended.More information can be found on :http://www.composites.ugent.be/PhD_job_vacancies_PhD_job_positions_composites.html

8063| University of Liverpool, Faculty of Health and Life Sciences| Postdoctoral Research Associate Grade 7 - Institute of Integrative Biology| We are seeking to recruit an innovative, motivated individual to join a Medical Research Council funded project led by Dr Kate Baker. Based at the Institute for Integrative Biology, you will work computationally on a large dataset of whole genome sequences from Shigella collected during the GEMS trial to inform treatment and management of shigellosis in resource-poor settings. The project will integrate genomic analyses with aspects of epidemiology, antimicrobial resistance and vaccine design. Collaborators include the Earlham Institute and the Centre for Vaccine Development at the University of Maryland, Baltimore. You should have (or be about to obtain) a PhD in microbial genomics or a related discipline, as well as some further skills specific to the role (see job description). You will have a strong track record of research outputs appropriate to your level, and be an otherwise well-rounded scientific researcher. The post is available for 35 months until 26 January 2022.

8028| Weizmann Institute of Science, Department of Molecular Cell Biology| A Postdoctoral position to study Triple-Negative Breast Cancer| A Postdoctoral position is available at the Weizmann Institute of Science to integrate into multidisciplinary projects associated with Triple-Negative Breast Cancer (TNBC) progression, heterogeneity and therapy. Ongoing studies are focused on signaling networks in TNBC subtypes, combination therapies and drug resistance, cancer stem cells, exosomes as biomarkers and the crosstalk between TNBC and the tumor microenvironment, in particular, with tumor associated macrophages. We employ multiple advanced experimental approaches using high-throughput screens, advanced molecular cell biology methods, cell signaling and bioinformatics tools utilizing in vitro cellular models and in vivo animal models as well as cancer patient samples. Candidates must have a background in cell signaling. Individuals with experience with animal models are preferred.Please address inquiries to:Prof. Sima LevDepartment of Molecular Cell Biology, The Weizmann Institute of Science,Rehovot 76100, Israel. Email: [email protected]: 972-8-934-2126 http://www.weizmann.ac.il/mcb/Lev/

8061| Dublin City University, Fraunhofer Project Centre| Postdoc in Microfluidics| Research Career Framework:As part of this role the researcher will be required to participate in the DCU Research Career Framework http://dcu.ie/hr/ResearchersFramework/index.shtml. This framework is designed to provide significant professional development opportunities to researchers and offer the best opportunities in terms of a wider career path. DCU has a strong track record in attracting both Irish and European Union research funding under Horizon 2020 (and all previous Framework Programmes), Marie Curie Actions and Erasmus. We offer a dynamic and internationally-focused environment in which you can advance your academic career. We offer an exciting research position in [email protected] – Ireland’s first Fraunhofer Project Centre for Embedded Bioanalytical Systems at Dublin City University. In collaboration with the Fraunhofer Institute for Production Technology (IPT) in Germany, [email protected] engineers and manufactures next-generation life-science technologies for the benefit of people and societies. [email protected] operates at the challenging crossroads of microsystems engineering and the life sciences. Common fields of application are in-vitro (“Point-of-Care”) diagnostics, pharma, life-science research, agrifood and environmental monitoring.Background & Role:You will develop microfluidic designs and manufacturing processes for typically polymer-based microfluidic systems towards high technology readiness levels (TRLs) within [email protected] In this role you will have access to competent technical, infrastructural and administrative support and the opportunity to evolve a multi-faceted skill set in an environment where you closely collaborate with world-class research organisations as well as domestic and international companies. Attractive career opportunities will arise with the success of [email protected] Duties and Responsibilities:You will be reporting to the [email protected] director or a manager appointed by him. Your duties will include, but are not limited to:• Development of microfluidic “Lab-on-a-Chip” systems by microfluidic design, experimental characterisation, modelling and simulation• Development of advanced manufacturing processes for high-TRL, polymer-based microfluidic “Lab-on-a-Chip” systems• Development of support instrumentation / optical detection platforms• Bioassay optimisation on microfluidic systems;• Support of project management, reporting and interactions with partners;• Support of project acquisition from industry and funding agencies;• Internal technical reporting;• Authoring of scientific publications and marketing activities;• Related administrative tasks.For covering these tasks, you can avail of [email protected]’s interdisciplinary staff competency matrix and training.Minimum Criteria:Applicants must have a PhD on a related topic; for Level 2 at least 4 years as postdoctoral researcher. Relevant experience in the design and testing of (typically polymer) microfluidic “Lab-on-a-Chip” systems for bioanalytical testing and their manufacture as well as in bioassay optimisation is desirable. Candidates will be assessed on the following competencies:Discipline specific knowledge and Research Skills (demonstrates knowledge of a research discipline and the ability to conduct a specific programme of research within that discipline)Communicating Research (Demonstrates the ability to communicate their research with their peers and the wider research community (for example presenting at conferences and publishing research in relevant journals) and the potential to teach and tutor students)Managing & Leadership skills (demonstrates the potential to manage a research project including the supervision of undergraduate students)Understanding the Research Environment (demonstrates an awareness of the research environment (e.g. funding bodies) and takes responsibility for how their research is conducted.

8072| Ghent University, Mechanics of Materials and Structures| Postdoctoral vacancy (36 months) on automated software workflow for medical application of 3D printed technologies| 3D printing or Additive Manufacturing (AM) technologies carry the promise of revolutionizing the quality and efficiency of healthcare. However, the required technologies, even when available, are currently too fragmented to be integrated into routine, affordable and streamlined solutions that can benefit a large number of patients. The challenge thereby is to deliver 3D printing technologies that enable:Patient-specific solutions: personalized medical devices that are designed using the images acquired for individual patients and best fit their treatment needs;Complexity and miniaturization: complex shapes, articulations and miniaturized geometries of implantable medical devices and instruments have the potential to radically enhance treatment effectiveness and post-treatment recovery;Streamlined care: the ability to integrate diagnosis, design and manufacturing of AM medical devices into a validated software platform is the key to delivering fast, affordable treatments with dramatic life-saving potential.The INTERREG project 3DMed aims to improve affordability and large-scale accessibility of medical treatment using 3D printed devices. This will be achieved by increasing the Technology Readiness Level (TRL) of state-of-the-art 3D printing technologies for medical applications and integrating them into a streamlined, fast, cost-effective software platform for use in routine clinical practice. This project contains 17 partners from The Netherlands, Belgium, France and United Kingdom, including universities, hospitals, software suppliers, 3D printing companies, clinical observers, manufacturers of medical devices and implants,... The project is coordinated by TUDelft.In this postdoctoral position, it is the purpose to develop a streamlined, fast, cost-effective software platform to connect the design and production of 3D printed devices with clinical evaluation (pre- and postoperative). This involves data transfer protocols to link image acquisition, design and the manufacture (3D printing) of the device; software collection and evaluation; software development; software interfacing; process automation; protocol collection and validation of the software platform for the selected categories of medical devices. Interfacing various software tools also involves formatting the input and output of each software so that automated interaction with the other software components is possible. Each input and output must be expressed in a terminology that is understandable by both clinicians and engineers and uses a consistent set of variables and measures for defining the medical device under consideration. Setting up this tool chain of different (commercial) software packages and programming the necessary data protocols to achieve an integrated software platform is the goal, and to achieve this goal, a close collaboration will be required with the researchers at TUDelft, clinical observers, AM service providers and software companies.Only candidates with a PhD degree or equivalent experience should apply. The candidate should have strong programming skills (Python, C++, C#,...) and has experience with different software tools for patient-specific design of implants, for example: (i) medical image segmentation software (Mimics, SimpleWare, Amira,...), (ii) FE tools (Abaqus, Ansys, Simcenter,...), (iii) topology optimization (Autodesk Within Medical, Altair/Optistruct, Frustum/Generate,...). He/she will closely work together with the other postdoc in the team (see other vacancy) and is willing to travel frequently to meet and discuss with the other project partners in the neighbouring countries.More information can be found on: http://www.composites.ugent.be/PhD_job_vacancies_PhD_job_positions_composites.html

8064| University of Liverpool, Faculty of Health and Life Sciences| Postdoctoral Research Associate Grade 7 - Functional and Comparative Genomics| The Betancourt laboratory seeks an individual with a background in bioinformatics and/or population genetics to lead a BBSRC funded project to quantify the fitness effects of transposable element insertions in Drosophila. A central goal of evolutionary genetics has been to understand the causes of variation in fitness between individuals. But, while the effects of DNA point mutations on fitness have been extensively studied, another potentially major source of mutations-- selfish transposable elements (TEs)-- has been largely neglected. Circumstantial evidence suggests that the contribution of TEs may be substantial: in Drosophila, they are the cause of most spontaneous mutations with abnormal phenotypes. We will measure the selective effects of TEs using a combination of deep sequencing, population genetic inference, functional Drosophila genetics, and laboratory assays.You will be part of a team including a full and part-time research technician, embedded in the research group of Andrea Betancourt in the Department of Evolution, Ecology and Behaviour within the Institute of Integrative Biology. This research group has tackled a wide variety of questions in evolutionary genetics, addressing the role of recombination and sex-linkage in evolution, and the evolutionary pressure imposed by selfish elements in Drosophila. The Institute for Integrative Biology boasts a state-of-the-art Drosophila laboratory, cutting-edge facilities in DNA sequencing, proteomics, and microscopy, and a thriving and productive research group working on evolutionary biology, ecology and behaviour.You should have a PhD degree in a relevant discipline (Biology, Genomics, Population Genetics, Evolution) and experience analysing large data sets. The post is available from 1 January 2019 to 14 July 2020.

8044| University of Edinburgh, School of Engineering| Research Associate in Kinetic Modelling of Liquid-Vapour Flows| A consortium of three internationally-leading UK institutions (Edinburgh University, Warwick University, and Daresbury Laboratory) are seeking a Research Associate to develop new modelling capabilities for multiscale interfacial fluid dynamics. This is part of a flagship £3.4M EPSRC Programme Grant targeting the multiscale fluid dynamics needed to simulate and design engineering flow systems of the future. This position is to work with Dr Livio Gibelli, Dr Matthew Borg, and Prof Jason Reese, in the School of Engineering in the University of Edinburgh. The start date is January 2019 (or another date, by arrangement), and is for 30 months. More information about the inter-institutional research partnership is at www.micronanoflows.ac.ukThe principal objectives of this research project are: • to apply and extend a mean-field kinetic theory approach to improve the fundamental understanding of non-equilibrium fluid flows involving phase change;• to develop numerical codes for the efficient simulation of liquid-vapour flows at the micro/nano-scale, including evaporation/condensation of droplets, nucleation dynamics, and bubble collapse.You should have a PhD, or equivalent experience, in mechanical or chemical engineering, or physics, or applied mathematics, or computational science. Preference will be given to those with expertise in: kinetic theory; stochastic particle methods for solving kinetic equations; physics of interfacial phenomena; numerical coding (possibly in Fortran). Candidates invited for interview will be informed no later than two working weeks after the close of applications.Closing date: 16 October 2018Vacancy number: 045138To apply please click the link below:https://www.vacancies.ed.ac.uk/pls/corehrrecruit/erq_jobspec_version_4.jobspec?p_id=045138

8060| Medical Research Council, The National Centre for the Replacement, Refinement & Reduction of Animals in Research| Programme Manager - In vitro Reporting Guidelines| Programme Manager - In vitro Reporting GuidelinesNC3Rs, LondonFixed Term, 3 years£37,769 to £44,396 (plus London allowances) The NC3Rs has a long-standing programme of work focusing on improving the design, analysis and reporting of animal experiments in order to ensure that studies are robust and reproducible, contribute to the knowledge base, and avoid the unnecessary use of animals. The team currently includes the NC3Rs lead for experimental design and two Science Managers.Key aspects of the programme include the ARRIVE reporting guidelines and the online Experimental Design Assistant (EDA). We are extending this programme of work to develop guidance to support improved reporting of in vitro research. These guidelines (working title, the RIVER guidelines - reporting In Vitro Experiments Responsibly) will optimise the reproducibility of in vitro studies and improve confidence in their validity to support wider uptake.Application of the 3Rs plays an essential role in achieving scientific excellence. The NC3Rs supports the development and uptake of new research tools and models with reduced reliance on the use of animals and/or improved animal welfare and its activities are divided between its role as a 3Rs research funder and programmes led by its own team of scientists. Further information can be found at www.nc3rs.org.uk You will need:• A PhD in a biological science, ideally with in vitro experience• Demonstrable knowledge/experience of systematic review and guidelines development• An understanding of the issues around the use of animals in research • Excellent communication and interpersonal skillsChoosing to come to work at the NC3Rs (part of UKRI) means that you will have access to a whole host of benefits from a defined benefit pension scheme and excellent holiday entitlement to access to employee shopping/travel discounts and salary sacrifice cycle to work scheme.For full details of this post and to complete an online application, visit https://mrc.tal.net/vx/lang-en-GB/mobile-0/appcentre-1/brand-3/xf-e4105499c463/candidate/so/pm/4/pl/1/opp/922-Programme-Manager-In-vitro-Reporting-Guidelines-NC3RS-922/en-GB and upload your CV along with a covering letter stating why you are applying for this role. Please quote reference number NC3Rs 922.The National Centre for the Replacement, Refinement & Reduction of Animals in Research is a body within UK Research and Innovation. UK Research and Innovation is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at www.ukri.org Closing date: 15 October 2018

8041| Queen Mary University of London, William Harvey Research Institute, Centre for Microvascular Research| Postdoctoral Research Assistant in Experimental Pathology of ACKR1; 2 positions| Postdoctoral Research Assistant in Experimental Pathology of ACKR1; 2 positionsThe William Harvey Research Institute (WHRI; www.whri.qmul.ac.uk) is a dynamic academic institution, with 90% of its research judged world-leading and internationally excellent (REF2014). WHRI, in a strategic partnership with the multi-disciplinary Centre for Inflammation and Therapeutic Innovation (CiTI; www.qmul.ac.uk/citi/) at the Queen Mary University of London (QMUL), is at the vanguard of uncovering molecular and cellular disease pathomechanisms and exploring innovative strategies for their effective therapies.Professor Antal Rot (http://www.qmul.ac.uk/whri/people/academic-staff/items/rotantal.html) is an internationally recognised pioneer investigator studying functions of chemokines and their receptors with particular focus on the mechanisms guiding their diverse pathophysiological roles. His group at the Centre of Microvascular Research, WHRI and CiTI uses modern tools of experimental pathology and immunology to uncover the multifaceted contributions of the atypical chemokine receptors to immunity and disease pathogenesis.In this context, supported by the Wellcome Trust Investigator Award to Professor Antal Rot, we are seeking to recruit 2 postdoctoral researchers who will conduct ground-braking world-class research on the contribution of ACKR1 expression in the erythroid compartment of the bone marrow to the pathophysiology of haematopoiesis and downstream effects in infection, inflammatory diseases and cancer. This work is of particular relevance to the health of individuals of African ancestry who due to the hugely prevalent SNP in ACKR1 gene do not express this receptor in erythroid cells. https://www.nature.com/articles/ni.3763The candidates should have relevant qualifications of PhD, MD, DVM or equivalent and have a strong track record of successful research as demonstrated by publications in renowned international journals.Both posts is for the period of 36 months, initially, with the possibility to extend for further 24 months. Starting salary will be in the range of £32,956 to £38,709 per annum inclusive of London Allowance, based on the QMUL pay scale as corresponding to the experience of candidates.Candidates must be able to demonstrate their eligibility to work in the UK in accordance with the Immigration, Asylum and Nationality Act 2006. Where required this may include entry clearance or continued leave to remain under the Points Based Immigration Scheme.For further information, please contact Professor Antal Rot ([email protected]l.ac.uk).Application queries can be directed to [email protected] apply, please visit the Human Resources website on http://www.jobs.qmul.ac.uk and search for reference QMUL14429.

8032| University College London, Institute of Cardiovascular Science| Research Associate in MR Physics and Machine Learning| Full Time The appointment will be on UCL Grade 7. The salary range will be £35,328 - £37,345 per annum, inclusive of London Allowance.In this project, we plan to develop rapid methods of assessing the anatomy and physiology using rapid imaging techniques and to use machine learning techniques to rapidly reconstruct heavily accelerated MR acquisitions. The appointee's main aims will be to modify and develop machine learning reconstruction methods for cardiovascular MR sequences to progress rapid methods of MR imaging. The postholder will be part of a multi-disciplinary group made up of MR Physicists, MR Physics PhD students and clinical academics. The group collaborates with the MR scanner manufacturer and has access to the cardiovascular pulse-programming environment. The appointment is funded to 31 May 2020 in the first instance.Candidates will have a PhD in a relevant subject area, or be in the final stages of writing up their thesis. They will demonstrate a high level of interest in the academic aspects of Imaging or Machine Learning with exposure to different research methods, together with experience in MR Reconstruction or Maching Learning with practical applications. An understanding of the basics of MRI and Machine Learning is essential.For further details about the vacancy and how to apply online please go to https://www.ucl.ac.uk/human-resources/working-ucl/jobs-ucl and search on Reference Number 1744462If you have any queries regarding the vacancy please contact Dr Vivek Muthurangu ( [email protected] ); for queries on the application process, contact [email protected] .Closing Date: 26 September 2018Latest time for the submission of applications: 23:59.Interview Date: TBCUCL Taking Action for EqualityWe will consider applications to work on a part-time, flexible and job share basis wherever possible.Our department holds an Athena SWAN Silver award, in recognition of our commitment and demonstrable impact in advancing gender equality.To apply click here https://atsv7.wcn.co.uk/search_engine/jobs.cgi?owner=5041178&ownertype=fair&jcode=1744462

8050| Kings College London, Department of Imaging Chemistry and Biology| Postdoctoral Research Associate in Radiochemistry| The salary will be paid at Grade 6, £37,412 to £44,105 per annum, inclusive of £3,223 per annum London Allowance.We are seeking a Postdoctoral Research Associate with experience in the design, synthesis, purification, and characterisation of novel organic compounds to work in the Molecular Imaging Lab in the Department of Imaging Chemistry and Biology (www.witneylab.com). The post holder will develop new chemistry and novel fluorine-18 labelled radiotracers for cancer imaging with positron emission tomography (PET) as well as synthesise and characterise a library of non-radioactive reference compounds and precursors for radiolabelling. In collaboration with the new GMP radiochemistry facility at KCL (the PERL), we will seek to translate these novel imaging methods to the clinic.The successful candidate will have extensive experience in both synthetic chemistry and fluorine-18 radiochemistry. This is an exciting opportunity to join a vibrant multidisciplinary research group within one of the premier biomedical imaging centres in Europe, where you will enjoy support in career development through Fellowship applications, networking events, and attendance at international conferences.This post will be offered on a fixed-term contract for 2 years.This is a full-time post.The selection process will include a panel interview and a presentation.For an informal discussion to find out more about the role, please contact Dr Tim Witney at [email protected] apply, please visit https://my.corehr.com/pls/kingrecruit/erq_jobspec_version_4.jobspec?p_id=003803 and register with the King’s College London application portal and complete your application online.Closing date: 7 October 2018