8491| Agri-Food and Biosciences Institute (AFBI)| Ruminant Livestock Production Research Scientist – Higher Scientific Officer – 40 month Fixed Term Contract| Further appointments may be made from this competition should AFBI positions become vacant which have similar duties and responsibilities.For more detailed information and to apply, please go to www.nicsrecruitment.org.ukAlternatively, an application pack can be requested by contacting:HRConnect, PO Box 1089, The Metro Building, 6-9 Donegall Square South, Belfast, BT1 9EW. Telephone: 0800 1 300 330. Email: [email protected] requests must include your name, address and reference number IRC238121Completed application forms must be returned to arrive not later than 12:00 noon (UK time) on Friday 7th June 2019.All applications for employment are considered strictly on the basis of merit. Applications are particularly welcomed from Roman Catholics and females as these groups are currently under-represented within AFBI.AFBI IS AN EQUAL OPPORTUNITIES EMPLOYERALL APPLICATIONS FOR EMPLOYMENT ARE CONSIDERED STRICTLY ON THE BASIS OF MERIT

8495| Imperial College London, Institute of Clinical Sciences, Faculty of Medicine| Research Associate| Applications are invited for a postdoctoral research position in the Reprogramming and Chromatin Group headed by Professor Petra Hajkova at the London Institute of Medical Sciences (LMS) in Imperial College London. The group studies molecular mechanisms underlying epigenetic reprogramming in vivo and in vitro (for further information, please visit http://www.lms.mrc.ac.uk/Research/Groups/EDC/ReprogrammingChromatin/)We are looking for a passionate scientist to join our efforts to elucidate molecular mechanisms implicated in the dynamic changes in nucleic acid modifications observed in early mouse embryo, developing germ line and pluripotent stem cells. The ideal candidate will have a solid background in epigenetics and/or in the field of nucleic acid chemistry and metabolism. Experience with HPLC and LC/MS would be highly desirable but not essential. Candidates who have not yet been officially awarded their PhD will be appointed as Research Assistant within the salary range £34,397- £37,486 p.a.For informal enquiries please contact Professor Petra Hajkova [email protected] technical issues when applying online please email [email protected] apply, please visit: https://www.imperial.ac.uk/jobs/ Closing date: 19 June 2019Committed to equality and valuing diversity, we are also an Athena SWAN Silver Award winner, a Stonewall Diversity Champion, a Disability Confident Employer and are working in partnership with GIRES to promote respect for trans people.The College is a proud signatory to the San-Francisco Declaration on Research Assessment (DORA), which means that in hiring and promotion decisions, we evaluate applicants on the quality of their work, not the journal impact factor where it is published. For more information, see https://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research- evaluation/The College believes that the use of animals in research is vital to improve human and animal health and welfare. Animals may only be used in research programmes where their use is shown to be necessary for developing new treatments and making medical advances. Imperial is committed to ensuring that, in cases where this research is deemed essential, all animals in the College’s care are treated with full respect, and that all staff involved with this work show due consideration at every level. http://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-integrity/animal-research/

8489| Institute of Cancer Research, Radiotherapy and Imaging| Postdoctoral Training Fellow in diffusion-weighted MRI for MR-guided radiotherapy| Diffusion-weighted MRI already plays an important part in cancer diagnosis and its results impact treatment decisions. Furthermore, it is expected to have a key role in unleashing the revolutionizing potential of MR-guided radiotherapy.This project aims at implementing distortion-less diffusion-weighted MRI with a particular focus on the Unity MR-Linac system, to enable daily functional MRI throughout the course of MR-guided radiotherapy. To meet the high requirements of radiotherapy in terms of spatial accuracy, in particular in the context of hypo-fractionated treatments, the successful applicant will have to combine MR pulse programming with state-of-the-art image reconstruction techniques, supported by dedicated high-performance hardware. The implemented technique will be tested in clinical studies regarding its value for assessment and prediction of treatment response. Another key aim of this project is the characterization of intravoxel incoherent motion (IVIM) with tailored diffusion-weighting gradient profiles.The post holder will drive the work forward within a multi-disciplinary team of computer scientists, medical physicists and clinicians within the Joint Department of Physics at the Institute of Cancer Research and the Royal Marsden NHS Foundation Trust. Results will be published in relevant high-impact journals and presented at national- and international conferences.Applicants will hold (or be very close to obtaining) a PhD in Physics, Engineering or another relevant field and ideally have experience in pulse sequence development and/or MR image reconstruction. It is anticipated that the starting salary will be in the range from £31,023* to £39,473 p.a. inclusive.*thesis submitted, awaiting PhD awardInformal enquiries can be made to Dr Andreas Wetscherek ([email protected]). Please do not send your application by email. To apply, please upload your CV and cover letter (addressing where you meet the person specification and including the names and addresses of two referees) using the ICR’s e-recruitment system, vacancy ref 730: www.icr.ac.uk/jobsearch

8505| University of Liverpool, Faculty of Science and Engineering| Postdoctoral Research Associate – Grade 7| The particle physics research group in Liverpool is looking for a highly motivated individual to work with us on the development of novel Depleted Monolithic Active Pixel Sensors (DMAPS) in industry standard High Voltage-CMOS (HV-CMOS) processes, aimed at future generations of fundamental physics experiments and other applications. Your research work will be focused on the design of DMAPS at the ASIC level, submission of the developed prototypes to silicon foundries and experimental characterization of the fabricated devices in the cleanrooms in Liverpool and elsewhere. Experience in the design of analog and/or digital CMOS/HV-CMOS circuits at the ASIC level, and with position sensitive particle detectors/imaging sensors, are desirable. You will play an important role in the design and characterisation programme of the prototypes. You will work closely with postgraduate research students at Liverpool and with collaborators from UK and international institutions. A willingness to travel within the UK and Europe, and the ability to communicate effectively with international collaborators, are essential. You should have a PhD in Electronic Engineering, Physics or equivalent. The post is available until 30 April 2023 with the possibility of an extension.For full details and to apply online, please visit: https://recruit.liverpool.ac.ukJob Ref: 011851/FPOSTClosing Date: 20 June 2019

8504| University of Otago, Faculty of Law| Postdoctoral Fellow - Law-1901075| Who we are:The University of Otago Legal Issues Centre ("the Centre") is housed in the Faculty of Law and conducts research on New Zealand's justice system that examines its accessibility, affordability, efficiency, fairness and accuracy, with the purpose of informing and influencing policy and conduct for the benefit of all New Zealanders.The roleThis position represents an exciting opportunity to join one of the country's most research intensive Universities and become part of a team helping to lead civil justice research in New Zealand.As a Postdoctoral Fellow in the Centre you will lead a study investigating pricing structures in the New Zealand civil litigation legal services market. In this role you be required to independently conduct research, analyse and report on the research findings. You will also be expected to publish these research findings in well-regarded journals and contribute to building the Centre's profile by supporting its media strategy.Your skills and experience• PhD in related discipline.• Experience conducting economic research and analysis.• Expertise in labour economics and/or the sociology of work is desirable.• Strong quantitative and/or qualitative research skills.• Proven track record of completing and publishing work.• Excellent oral and written communication skills.• Commitment to collegiality, teamwork, collaboration, and cooperation.Further details:This is a full-time, fixed-term position for two years from a date to be mutually agreed.Ideally, this role will be based in Dunedin, however, we are open to an appointment in another New Zealand city by negotiation with the Centre Director.Application:Applications quoting reference number 1901122 will close on Friday, 21 June 2019.APPLICATION INFORMATION:To see a full job description and to apply online go to: https://otago.taleo.net/careersection/2/jobdetail.ftl?job=1901075Equal opportunity in employment is University policy.E tautoko ana Te Whare Wananga o Otago i te kaupapa whakaorite whiwhinga mahi.

8486| Univeristy of Cambridge, Dept of Chemistry| Research Associate - Bioelectrochemistry and Spectroscopy (Fixed Term)| Fixed-term: The funds for this post are available for 2 years in the first instance. Applications are invited for a Postdoctoral Research Associate (PDRA) to work in the Reisner group in the Department of Chemistry at the University of Cambridge, UK. The project is part of a European Research Council (ERC) and Leverhulme Trust funded project on protein electrochemistry and spectroscopy. The ERC funded project (0.7 FTE) on 'Semi-artificial photosynthesis with wired enzymes' aims to integrate enzymes into porous electrodes to explore novel pathways for efficient solar-to-chemical conversion. We thereby address the need for new innovations in the solar fuels field and develop a new chemical biology platform, in which biological pathways can be systematically re-wired in vitro to characterise important metabolic processes, such as water splitting and CO2 utilisation. Central to this project is materials design (in particular 3D electrode architectures), where materials will be tailored to the dimensions and functions of the enzymes, as well as the development of spectroelectrochemical techniques to deepen our understanding of the enzyme-material interface. The Leverhulme Trust funded project (0.3 FTE) is closely connected with the goals of the ERC-project and will be executed in collaboration with Dr Maxie Roessler from Imperial College London (https://www.imperial.ac.uk/people/m.roessler). This project on "Film-electrochemical EPR: a new method to investigate redox-based catalysis" is intended to pioneer EPR spectroelectrochemistry of immobilised proteins using porous metal oxide electrodes.Applicants should have (or be about to obtain) a PhD in Chemistry, Biochemistry, Materials Science, Electrochemistry, Spectroscopy or a closely related discipline. A strong background in bioelectrochemistry, catalysis, materials chemistry and/or spectroscopy are desirable for the position. The applicant should also have experience in coordinating activities as part of a larger interdisciplinary team. Candidates are encouraged to think outside of their formal field of training to fit into a creative, collaborative and dynamic research environment. A strong record of research productivity, reflected in a strong publication record as well as excellent communication, management and English writing skills will be required. The successful candidate will also be expected to help guiding undergraduate and postgraduate students as well as taking on laboratory management duties. More information about the Reisner group, including relevant publications, can be found at http://www-reisner.ch.cam.ac.uk/. Recent reviews on this topic are available here: Kornienko, Ly, Robinson, Heidary, Zhang & Reisner, Acc. Chem. Res. 2019, in print (DOI: 10.1021/acs.accounts.9b00087); Kornienko, Zhang, Sakimoto, Yang & Reisner, Nature Nanotechn. 2018, 13, 890-899 (DOI: 10.1038/s41565-018-0251-7). To apply online for this vacancy and to view further information about the role, please visit :http://www.jobs.cam.ac.uk/job/21403. Please ensure that you upload your Curriculum Vitae (CV), a covering letter and include a publications list in the upload section of the online application. If you upload any additional documents that have not been requested, we will not be able to consider these as part of your application. For queries relating to your application or the application process, please contact Inger Lomax (administrator of the Reisner laboratory) via email on [email protected] Please quote reference MA19027 on your application and in any correspondence about this vacancy. The Department holds an Athena SWAN silver award for women in Science, Technology, Engineering, Mathematics, and Medicine. The University actively supports equality, diversity and inclusion and encourages applications from all sections of society. The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

8490| University College London, Department of Medical Physics and Biomedical Engineering| Research Fellow in Brain Image Analysis| UCL is one of the foremost universities in Britain and the world. The Department of Medical Physics & Biomedical Engineering is proud to host internationally-leading research groups covering a broad range of activities and spread over several sites. Our staff and students have a diverse range of interests and expertise, covering many areas of physics, engineering, medicine, physiology, computer science, and mathematics. This provides a highly stimulating multidisciplinary environment for learning and for scientific research. In addition to our research activities, we run a variety of undergraduate and graduate degree programmes. We are now seeking to appoint a Research Fellow (PDRA) with two purposes. First, to improve our reconstruction tools using deep learning based registration techniques, in order to produce an accurate 3D atlas. And second, to collaborate in the development of segmentation techniques that apply the atlas to the automated analysis of in vivo MRI scans. The latter task involves assisting Dr. Iglesias in the supervision of a doctoral student who is working on a related task. This project provides an exciting opportunity at the interface between histology, neuroscience, biomedical imaging, computer vision and statistics, with a huge potential imaging in the neuroimaging field. The postholder will be expected to produce implementations that will be made publicly available to the research community, as part of the widespread package FreeSurfer. The post holder will be integrated with the UCL Centre for Medical Image Computing (CMIC), which will be soon co-located with the new UCL AI Centre on High Holborn. In addition, the postholder will have the opportunity of visiting labs at MIT and the Martinos Center (MGH/Harvard Medical School) in Boston, where Dr. Iglesias holds affiliate / part-time appointments. Starting date is flexible but would ideally be September 2019 at the latest. The position is for 2 years in the first instance.Applicants must have a PhD or about to submit a PhD or equivalent research experience in biomedical image analysis. Good publication track record in top medical imaging journals and conferences (IEEE-TMI, Medical Image Analysis, MICCAI, IPMI) and Strong expertise in programming or using high-level languages or packages (e.g. C/C++, Matlab). Experience with deep learning packages (e.g., TensorFlow, Keras, PyTorch) and Background in Bayesian inference are desirable. Appointment at Grade 7 is dependent upon having been awarded a PhD. Or if about to submit a PhD, the appointment will be at Grade 6B (£30,922 - £32,607 salary, inclusive of London Allowance) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis.Further information about the Department of Medical Physics and Biomedical Engineering can be found here https://www.ucl.ac.uk/medical-physics-biomedical-engineering/For further details about the vacancy and how to apply online please go to https://www.ucl.ac.uk/human-resources/working-ucl/jobs-ucl and search on Reference Number 1803717.For informal queries about the position, please contact Dr Juan Eugenio Iglesias [email protected] If you have any queries regarding the application process, please contact Tracy Pearmain on [email protected] Closing Date: 1/6/2019Latest time for the submission of applications: 23:59Interview Date: TBCUCL Taking Action for EqualityWe will consider applications to work on a part-time, flexible and job share basis wherever possible.Our department holds an Athena SWAN Bronze award, in recognition of our commitment to advancing gender equality.To apply click here https://atsv7.wcn.co.uk/search_engine/jobs.cgi?owner=5041178&ownertype=fair&jcode=1803717

8500| ENSEA, ETIS| Two Post-doctoral Researcher Positions on “IoT security” and on “Non Orthogonal Multiple Access (NOMA) Techniques for B5G Networks”| Two Post-doctoral Researcher Positions on “IoT security” and on “Non Orthogonal Multiple Access (NOMA) Techniques for B5G Networks” 1) Post-doc on “IoT Security”: Reference ELIOT Starting date: September / October 2019 (negotiable if necessary) Full-time, 1.5-year fixed term contract, remuneration: 50 kEuros/year (~2,200 - 2,500 Euros/month net salary) plus conference attendance and travel expenses to Brazil for project meetings.Description: The post-doc will work on the project ELIOT “Enabling technologies for IoT” https://eliot.ensea.fr/, funded by the French National Research Agency (ANR), in collaboration with the Universities of Sao Paulo USP and PUC-Rio in Brazil. Applications are sought from international candidates with an outstanding academic background and expertise in at least one of the following areas:o physical layer security, secret key generation at PHYo localization-based authenticationo anomaly detection / hardware security o IoT securityand related disciplines. Demonstrable mathematical skills and familiarity with IoT security standards will be an advantage. Experience in proposal writing will be an advantage. 2) Post-doc on “NOMA Techniques for B5G Networks”: Reference eNiGMA Starting date: September / October 2019 (negotiable if necessary) Full-time, 2-year fixed term contract, remuneration: 50 kEuros/year (~2,200 - 2,500 Euros/month net salary) plus conference attendance expenses to international venues. Description: The post-doc will work on the “Paris Seine Excellence Initiative” funded project eNiGMA “NOMA schemes for fifth generation and beyond systems under security and delay constraints”. Applications are sought from international candidates with an outstanding academic background and expertise in at least one of the following areas:o wireless communications and NOMA techniqueso discrete and convex optimization theoryo delay constrained systems / ultra-reliable low latency communications (URLLC) o uplink strategies in massive machine type communications (mMTC)Demonstrable mathematical skills are essential. Experience in proposal writing is highly desirable.About the opportunity and usThe two postdoctoral researchers will join the ETIS Laboratory UMR 8051 and will work under the supervision of Dr. Arsenia (Ersi) Chorti for the position “ELIOT” and Dr. Arsenia (Ersi) Chorti and Prof. Inbar Fijalkow for the position “eNiGMA”. Informal enquiries about these positions can be made by email to Dr. Arsenia (Ersi) Chorti [email protected] Both postdocs will be located at the École Nationale Supérieure de l'Électronique et de ses Applications (ENSEA), a reputable Engineering School (“Grande Ecole”) at the outskirts of Paris (line RER A, station Cergy Prefecture) in France.About youApplicants must have (or be close to completion) a PhD degree in a relevant area, a good publication record and should be familiar with key engineering programming languages (e.g., MATLAB, Python, R, etc.). Strong interpersonal and communication skills, the ability to work effectively in a team, manage resources and prioritise tasks to achieve project outcomes will be essential. A good knowledge of the English language is required. Knowledge of French is not a pre-requisite.How to ApplyApplication procedure: Applications should include the following elements: 1) detailed CV, 2) one-page motivation letter, 3) two or three academic references. All applications must be submitted directly by email at [email protected] For applications for the post-doc ELIOT, the subject of your email should be “Application for ELIOT post-doc”, for applications for the post-doc eNiGMA the subject of your email should be “Application for eNiGMA post-doc”. Closing date: 11:59 pm 5th July 2019 (GMT+1 Time Zone)Interviews will be conducted in person (upon availability) or by phone / videoconference between 8-12 July 2019.We are committed to diversity and social inclusion. Applications from female candidates, people with disabilities and diverse backgrounds are encouraged.We reserve the right not to proceed with any appointment

8496| University of Pretoria, Centre for Microbial Ecology and Genomics| Post-Doc Researcher| A Post-Doctoral position in the field of microbial metagenomics are currently available in CMEG, one of the University of Pretoria’s leading research institutes. The post is offered on a 1-year basis renewable for up to 3 years, subject to performance. Applicants are required to have a PhD in a relevant field (e.g., microbial ecology, microbial genetics, metagenomics, genomics and bioinformatics). Previous post-doctoral experience and a record of good publications will be an added advantage. The research project available are in the field of hot and cold desert microbial ecology and metaviromics. The project is in collaboration with other national and/or international laboratories.

8487| Univeristy of Cambridge, Dept of Chemistry| Research Associate - Photocatalysis (Fixed Term)| Fixed-term: The funds for this post are available for 2 years in the first instance.Applications are invited for a Postdoctoral Research Associate (PDRA) to work in the Reisner group in the Department of Chemistry at the University of Cambridge, UK. The project is part of a Leverhulme Trust funded project entitled 'Optofluidic microreactors for advanced photocatalysis'. Producing renewable solar fuel by Artificial Photosynthesis and sustainable chemicals by photoredox catalysis is recognised as a promising solution to the energy & environmental crisis, but these approaches are facing critical roadblocks in technology development.This interdisciplinary project tackles the main problems holding back exploitation of photocatalysis: lack of quantitative in-operando (during reaction) analysis and therefore fundamental understanding. We will develop optical detection strategies based on hollow-core photonic crystal fibre, whose glass microstructure guides light through metre-long microfluidic channels. The resulting optofluidic microreactors enable ultrasensitive absorption spectroscopy within minute reaction volumes (several nL per cm). By combining fibres with microfluidic circuits, we will create a rapid screening platform for photocatalysts and flow-chemistry in general. This project will be executed in collaboration with the group of Dr Tijmen Euser, Cavendish Laboratory, University of Cambridge (www.np.phy.cam.ac.uk/research-themes/optofluidics). Work of this PDRA based in Chemistry will therefore be closely executed with the Tijmen team in the Physics department.Applicants should have (or be about to obtain) a PhD in Chemistry, Materials Science, or a closely related discipline. A strong background in photocatalysis is required and knowledge in materials chemistry, mechanistic chemistry, microfluidics and spectroscopy are desirable for the position. The applicant should have experience in coordinating activities as part of a larger interdisciplinary team. Candidates are encouraged to think outside of their formal field of training to fit into a creative, collaborative and dynamic research environment. A strong record of research productivity, reflected in a strong publication record as well as excellent communication, management and English writing skills will be required. The successful candidate will also be expected to help guiding undergraduate and postgraduate students as well as taking on laboratory management duties.More information about the Reisner group, including relevant publications, can be found at www-reisner.ch.cam.ac.uk. Recent reviews on this topic are available here: Dalle, Warnan, Leung, Reuillard, Karmel & Reisner, Chem. Rev. 2019, 119, 2752-2875; Hutton, Martindale & Reisner, Chem. Soc. Rev. 2017, 46, 6111-6123; Willkomm, Orchard, Reynal, Pastor, Durrant & Reisner, Chem. Soc. Rev. 2016, 45, 9-23; Cubillas, Unterkofler, Euser, Etzold, Jones, Sadler, Wasserscheid & Russell, Chem. Soc. Rev., 2013, 42, 8629-8648.To apply online for this vacancy and to view further information about the role, please visit: www.jobs.cam.ac.uk/job/21404Please ensure that you upload your Curriculum Vitae (CV), a covering letter and include a publications list in the upload section of the online application. If you upload any additional documents that have not been requested, we will not be able to consider these as part of your application.For queries relating to your application or the application process, please contact Inger Lomax (administrator of the Reisner laboratory) via email on [email protected] quote reference MA19028 on your application and in any correspondence about this vacancy.The Department holds an Athena SWAN silver award for women in Science, Technology, Engineering, Mathematics, and Medicine.The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

8507| University College London, Medical Physics and Biomedical Engineering| Research Fellow in Photoacoustic Wavefront Shaping Instrumentation, - Ref:1804152| Applications are invited for a postdoctoral research position to work on the development of optics and ultrasonics based techniques for controlling illumination patterns of light inside scattering media such as biological tissue for biomedical imaging applications. The aim of the project will be to design and evaluate optical wavefront shaping systems - systems that iteratively search for an optimised wavefront correction to apply to an incident light field in order to produce a desired illumination pattern (e.g. a tight focus) inside a scattering medium. A key aspect will be investigating the use of photoacoustic (optically generated ultrasound) signals as a feedback mechanism to guide the wavefront shaping process. The project will involve constructing benchtop experimental setups comprising (CW and ns pulsed) laser sources, optical amplitude and phase control systems (e.g. spatial light modulators) and ultrasonic detectors. It will also involve developing system control software and implementing and evaluating new wavefront optimisation algorithms. The post is available immediately, and is initially funded for 2 years with possible extension subject to funding.A postdoctoral optical physicist or engineer with a strong track record of research achievement (or the potential to acquire one) is sought. A strong applied optics background is required with experience of optical system design, lasers, free-space optics and preferably experience using phase control systems such as spatial light modulators or interferometers. Knowledge of some or all of the following would also be advantageous: photoacoustics, ultrasonics, electronics, signal processing, computer controlled data acquisition and programming. Candidates must have a PhD (or equivalent) or be about to submit a PhD in engineering, physics, or a related discipline. Candidates must have good demonstrable practical skills in physics and/or engineering. An ability to build novel bench top optical systems and instrumentation and make precise measurements and experience of experimental applied optics and optical systems is required. Experience of Labview and Matlab programming is desirable. Appointment at Grade 7 is dependent upon having been awarded a PhD. Or if about to submit a PhD, the appointment will be at Grade 6B (£30,922 - £32,607 salary, inclusive of London Allowance) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis.For further details about the vacancy and how to apply online please go to https://www.ucl.ac.uk/human-resources/working-ucl/jobs-ucl and search on Reference Number 1804152. Further information about the Department of Medical Physics and Biomedical Engineering can be found here https://www.ucl.ac.uk/medical-physics-biomedical-engineering/Further information on the research activities of the Photoacoustic Imaging Group can be found at: http://www.medphys.ucl.ac.uk/research/mle/index.htm For informal queries about the position, please contact Dr James Guggenheim on [email protected] you have any queries regarding the application process, please contact Tracy Pearmain on [email protected] Closing Date: 9 June 2019Latest time for the submission of applications: 23:59.Interview Date: TBCUCL Taking Action for EqualityWe will consider applications to work on a part-time, flexible and job share basis wherever possible.Our department holds an Athena SWAN Bronze award, in recognition of our commitment to advancing gender equality.To apply click here: https://atsv7.wcn.co.uk/search_engine/jobs.cgi?owner=5041178&ownertype=fair&jcode=1804152

8474| University of Manchester, Cancer Research UK Manchester Institute| Postdoctoral Scientist – Prostate Oncobiology| We are looking for a highly-motivated Postdoctoral Scientist to join Dr Baena’s Prostate Oncobiology group to study the role of inflammation on prostate tumour initiation and how to prevent their progression to metastatic prostate cancer.Prostate cancer (PCa) is the second leading cause of cancer-related mortality in men worldwide, accounting for 15% of all male cancer deaths. PCa patients exhibit a high heterogeneity both clinically and biologically highly variable clinical behaviour; some have indolent disease whilst in others it is lethal. Although the initial response to androgen deprivation therapy is almost universal, progression to castration resistant state is inevitable and lethal. Previous work from our laboratory shows the importance of further understanding molecular events leading to castration-resistant prostate cancer as they’re key for the development of improved therapies for such patients (Barros-Silva et al., 2018; Parry et al., 2019; Baena et al., 2013). Thus, the post holder will work on defining the modification on tumour microenvironment (TME) driven by tumour-stem cell to promote castration-resistant stage. This study will provide new avenues to prevent prostate tumour progression and metastasis by combining anti-tumour and anti-TME (e.g. immune) interventions for prostate cancer patients.About you:You will have a PhD in a relevant related subject and have research laboratory experience. You will also have profound knowledge in cellular and molecular biology and have experience of working with in vivo cancer models. You will have significant experience of cell culture, particularly in vitro 3D culture systems and handling primary cells. Profound experience in FACS analyses and lineage tracing work is also essential for this position. This is an exciting opportunity for you to be involved in developing and driving the project as well as writing up work for presentation and publication. Why choose Cancer Research UK Manchester Institute?The Cancer Research UK Manchester Institute (www.cruk.manchester.ac.uk), an Institute of The University of Manchester (www.manchester.ac.uk), is a world-leading centre for excellence in cancer research. The Institute is core funded by Cancer Research UK (www.cancerresearchuk.org), the largest independent cancer research organisation in the world. We are currently situated at the internationally-renowned life sciences campus at Alderley Park in Cheshire England, 15 miles from Manchester, a vibrant and dynamic city surrounded by beautiful countryside. We are partnered with The Christie NHS Foundation Trust (adjacent to the CRUK Manchester Institute, Paterson Building) in South Manchester (www.christie.nhs.uk), one of the largest cancer treatment centres in Europe. The CRUK Manchester Institute is a key part of the Belfast-Manchester Movember Centre of Excellence for Prostate Cancer. As well as bringing together expert researchers and clinicians, the Movember Centres of Excellence will also provide a world-class training ground for the scientists of the future, building a legacy of top prostate cancer researchers in the UK, as well as establishing international collaborations for the brightest minds to tackle the most important questions in prostate cancer research – now and into the future.How to apply?To apply for this position please visit our website: http://www.cruk.manchester.ac.uk/Opportunities/Opportunities-Home For any informal enquiries about this post, please contact Dr Esther Baena, email: [email protected] Closing date: Sunday 2 June 2019.

8488| Institute of Cancer Research, Radiotherapy and Imaging| Postdoctoral Training Fellow in diffusion-weighted MRI for MR-guided radiotherapy| Diffusion-weighted MRI already plays an important part in cancer diagnosis and its results impact treatment decisions. Furthermore, it is expected to have a key role in unleashing the revolutionizing potential of MR-guided radiotherapy.This project aims at implementing distortion-less diffusion-weighted MRI with a particular focus on the Unity MR-Linac system, to enable daily functional MRI throughout the course of MR-guided radiotherapy. To meet the high requirements of radiotherapy in terms of spatial accuracy, in particular in the context of hypo-fractionated treatments, the successful applicant will have to combine MR pulse programming with state-of-the-art image reconstruction techniques, supported by dedicated high-performance hardware. The implemented technique will be tested in clinical studies regarding its value for assessment and prediction of treatment response. Another key aim of this project is the characterization of intravoxel incoherent motion (IVIM) with tailored diffusion-weighting gradient profiles.The post holder will drive the work forward within a multi-disciplinary team of computer scientists, medical physicists and clinicians within the Joint Department of Physics at the Institute of Cancer Research and the Royal Marsden NHS Foundation Trust. Results will be published in relevant high-impact journals and presented at national- and international conferences.Applicants will hold (or be very close to obtaining) a PhD in Physics, Engineering or another relevant field and ideally have experience in pulse sequence development and/or MR image reconstruction. It is anticipated that the starting salary will be in the range from £31,023* to £39,473 p.a. inclusive.*thesis submitted, awaiting PhD awardInformal enquiries can be made to Dr Andreas Wetscherek ([email protected]). Please do not send your application by email. To apply, please upload your CV and cover letter (addressing where you meet the person specification and including the names and addresses of two referees) using the ICR’s e-recruitment system, vacancy ref 728: www.icr.ac.uk/jobsearch

8506| University College London, Medical Physics and Biomedical Engineering| Research Fellow in Clinical Photoacoustic Imaging Instrumentation, - Ref:1804428| Applications are invited for a postdoctoral research position to work on the development of a novel clinical photoacoustic scanner for imaging cancer and other diseases.The aim of the project is to optimise aspects of an existing scanner design based upon an optical interferometric ultrasound sensor and develop a compact, mobile instrument that can be used in a hospital environment for clinical studies. The project will be highly interdisciplinary encompassing optical hardware and instrument design, biomedical optics, software development and image analysis. A component of the project may also involve conducting clinical studies in collaboration with clinicians at UCL Hospitals.This post offers an opportunity to undertake translational research in photoacoustic imaging within an internationally leading research group and make a major impact on the clinical application of a promising new medical imaging technique.The post is available immediately, and is initially funded for 2 years with possible extension subject to funding.Key RequirementsA postdoctoral engineer or physicist with strong practical engineering skills and an interest in the clinical translation of research is sought. Candidates must have a PhD (or equivalent) or be about to submit a PhD in engineering, physics, or a related discipline. Experience of optical system design, lasers, free-space and fibre optics, PC based data acquisition and instrumentation control and a knowledge of laser-tissue interactions is desirable. Good inter-personal skills and an ability to work well in a multidisciplinary team of engineers, physicists and clinicians are essential. Experience of some or all of the following would also be advantageous: interferometry, optical scanners, Labview programming, tissue optics, optical spectroscopy and in vivo optical or ultrasound measurements in a clinical environment.Appointment at Grade 7 is dependent upon having been awarded a PhD. Or if about to submit a PhD, the appointment will be at Grade 6B (£30,922 - £32,607 salary, inclusive of London Allowance) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis.Further Details:For further details about the vacancy and how to apply online please go to http://www.ucl.ac.uk/hr/jobs and search on Reference Number 1804428. Further information about the Department of Medical Physics and Biomedical Engineering can be found here: http://www.ucl.ac.uk/medphys/ Further information on the research activities of the Photoacoustic Imaging Group can be found at: http://www.medphys.ucl.ac.uk/research/mle/index.htm For informal queries about the position, please contact Prof Paul Beard on [email protected] If you have any queries regarding the application process, please contact Tracy Pearmain on [email protected] apply click here: https://atsv7.wcn.co.uk/search_engine/jobs.cgi?owner=5041178&ownertype=fair&jcode=1804428 UCL Taking Action for EqualityWe will consider applications to work on a part-time, flexible and job share basis wherever possible.Closing Date: 13 June 2019Latest time for the submission of applications: 23:59Interview date: TBCOur department holds an Athena SWAN Bronze award, in recognition of our commitment to advancing gender equality.This appointment is subject to UCL Terms and Conditions of Service for Research and Support Staff.

8503| Invicro| Senior Imaging Scientist| Applications are invited for a Senior Imaging Scientist position to work within the Discovery Research (DR) group based in London. We are seeking a Senior Imaging Scientist to design and facilitate the execution and analysis of preclinical imaging studies as well as drive new business opportunities with existing and potential Sponsors. The individual should enjoy challenging and analytical work and be motivated by the idea that together we can accomplish great things and make a positive contribution to society through our mission. The RoleThe Senior Imaging Scientist is expected to design and facilitate the execution and analysis of preclinical imaging studies within the DR group and will also play a leading role in business development activities. The ideal candidate will have experience with pre-clinical in vivo imaging techniques including understanding of theory, familiarity with data acquisition and analysis techniques, and experience in quality control and presentation of such data. They will be expected to plan, execute and manage preclinical imaging studies across various therapeutic areas and modalities, in addition to providing guidance and support for analysis of data. The CandidateCan demonstrate the ability to manage multiple projects at once. The candidate must be able to work quickly and accurately and pay strict attention to detail. They must be adaptable and capable of working and leading in a team environment. In addition, they must be able to professionally and confidently interact with customers and subcontractors, as well as prepare and deliver written and oral summaries of work. They will be highly motivated and able to deliver to defined timelines, in collaboration with colleagues from the preclinical sciences and image analysis groups.Key Duties:• Manage the design, execution, analysis and reporting of pre-clinical discovery research studies whilst following the DR study workflows and ensuring collected and reported data is of high standard. • Be the sponsor facing scientist with the responsibilities of updating the sponsor during protocol development, during key study milestones, and presenting the results.• As the study director on multiple projects you are ultimately responsible for:o All internal and external study related communications.o Creating and maintaining an open and supportive internal team environment. o Sufficient knowledge on the disease of interest, its basic biology and how the specific study fits within that field to engage in discussions with sponsor o The integrity and quality of the data shared to the sponsor.• Support execution of pre-clinical imaging studies across various therapeutic areas• Support fellow Imaging Scientists in your key areas of expertise• Interface with business development, sponsors, study managers, and laboratory staff to manage all aspects of study management from proposal to final report• Author and review technical documents including study protocols, final reports, abstracts/manuscripts/white papers, etc. • Represent Invicro externally in a professional manner• Drive new business development opportunitiesTo be considered for this position, you will have:• Scientific/technical PhD with appropriate industry experience or Scientific/technical Masters with appropriate industry experience. PhD or MS in a relevant field (e.g. engineering, physics, chemistry or biology)• Significant experience with small molecule radiochemistry and/or radio- or fluorescent labeling of proteins and/or MRI, PET, SPECT, CT, or other relevant imaging modality required• Experience with the application of molecular imaging to study drug effects, biodistribution, and target engagement• Superior skills related to teamwork, multi-tasking, and time/project management• Ability to work quickly with strict attention to detail• Ability to demonstrate adaptability and past leadership experience in a team environment• Ability to interact professionally and confidentially with customers and subcontractors• Ability to prepare and deliver written and oral scientific summaries of work• Excellent communication skillsCompetitive Salary & Benefits Bonus, Contributory Pension, Private Medical Insurance, Life Assurance & Flexible Benefits options.To apply for this position please forward your CV and a covering letter detailing your relevant experience to [email protected] ensure compliance with Data Protection laws and you can find our Privacy Notice on Invicro IntranetImanova is an equal opportunities employer and positively encourages applications from suitably qualified and eligible candidates regardless of sex, race, disability, age, sexual orientation, gender reassignment, religion or belief, marital status, or pregnancy and maternity.

8497| University of Manchester, Cancer Research UK Manchester Institute| Postdoctoral Scientist – Cell Signalling Group| - Salary in the range of £31,604 - £41,929 (dependent upon qualifications and experience)- Job Ref: MI/19/20 - Duration of position: 3 yearsAbout the role:We are looking for a highly motivated Postdoctoral Scientist to join the Cell Signalling laboratory of Prof. Angeliki Malliri (http://www.cruk.manchester.ac.uk/Our-Research/Cell-Signalling) aiming to identify novel molecular targets for KRAS mutant non-small cell lung cancer, the most common subtype of this cancer, by discovering and contrasting signalling events associated with particular mutant alleles of KRAS. In addition the role will involve examining resistance mechanisms to novel agents targeting KRAS.About you:You should have a PhD in molecular and cellular biology along with a knowledge of the essentials of biochemistry and genetics. A background in bioinformatics and in vivo models of cancer is desirable but not essential.Why choose Cancer Research UK Manchester Institute?The Cancer Research UK Manchester Institute (www.cruk.manchester.ac.uk), an Institute of The University of Manchester (www.manchester.ac.uk), is a world-leading centre for excellence in cancer research. The Institute is core funded by Cancer Research UK (www.cancerresearchuk.org), the largest independent cancer research organisation in the world. We are currently situated at the internationally-renowned life sciences campus at Alderley Park in Cheshire England, 15 miles from Manchester, a vibrant and dynamic city surrounded by beautiful countryside. We are partnered with The Christie NHS Foundation Trust in South Manchester (www.christie.nhs.uk), one of the largest cancer treatment centres in Europe. These factors combine to provide an exceptional environment in which to pursue basic, translational and clinical research programmes.The CRUK Manchester Institute is a key partner of the CRUK Lung Cancer Centre of Excellence together with UCL, which brings together a unique range of internationally renowned scientists and clinicians within the field of lung cancer research. The Centre combines expertise in basic, translational and clinical research. It is committed to delivering an outstanding lung cancer training programme and building a world class centre of excellence in lung cancer research.How to apply?To apply for this position please visit our website: http://www.cruk.manchester.ac.uk/Opportunities/Opportunities-Home For any informal enquiries about this post, please contact Prof. Angeliki Malliri via email: [email protected] for receipt of applications: 16 June 2019.

8511| Science & Technology Facilities Council (STFC)| Project Manager for CEDA Data/IT Projects| Project Manager Rutherford Appleton Laboratory, Harwell Campus, OxfordshireSalary £38,318 - £42,576 (dependent upon qualifications and experience)Open EndedFull time or part time considered / Flexible hours consideredAbout UsThe Science and Technology Facilities Council (STFC) is one of Europe’s largest research organisations. Through combining world-class facilities with major international collaborations, and some of the world’s most talented staff, we’re driving ground-breaking advances in science and technology / engineering.The STFC Centre for Environmental Data Analysis (CEDA) exists to enable the efficient delivery of environmental science programmes through effective data services and computational infrastructure. Substantial infrastructure investment in recent years has given CEDA a high performance data analysis facility (JASMIN) to support the analysis and distribution of data from the European space programme (Copernicus) and the climate model projections underpinning discussions on climate change, and many other high profile environmental datasets. STFC is one of nine partner organisations that have been brought together to create UK Research and Innovation (UKRI); a new organisation with a vision to ensure the UK maintains its world-leading position in research and innovation. STFC offers a benefits package designed to provide an excellent work/life balance. This includes 30 days’ annual leave, 10.5 public and privilege days, Christmas shut down, flexible working hours, a workplace nursery, an exceptional defined benefit pension scheme, and social and sporting activities and societies.About The RoleWithin STFC CEDA a team of data managers, scientists and software developers provide new and innovative applications and services that enable end-users to access and exploit atmospheric, satellite and environmental data holdings. CEDA collaborates with leading scientists and software developers from the UK and internationally. Major activities include running Atmospheric Science and Earth Observation data archives for the Natural Environment Research Council (NERC), working with the Met Office on high-resolution climate model simulations and supporting multi-Petabyte satellite data processing systems for the European Space Agency.We now have an excellent opportunity for a Project Manager to join us to work on a number of ongoing and new projects. This portfolio of projects covers a wide range of data related topics (environmental data management, e-infrastructure, cloud computing, data acquisition, development of standards). As Project Manager you will have the opportunity to work on environmental data, software and infrastructure projects at all stages of implementation; from the proposal stage right through to deployment, operation and supportResponsibilities will include:• Managing projects and/or significant work packages.• Managing multidisciplinary, cross-organisational and international teams to produce project deliverables.• Managing sub-contractors and consortium partners, nationally and internationally.• Reporting to Customers on all aspects your projects using written reports, Gantt charts and presentations.• Leading a team of specialists preparing proposals for future lines of work.• Reporting project finance and schedule to CEDA’s Senior Management Team.• Providing advice and training on project management matters to junior members of staff.• Promoting improvements to project management tooling and practice within CEDA.About YouTo be successful in this role you will be educated to degree level or equivalent, ideally in a Computing or Physical Science, Engineering or Mathematics subject. You will have expertise in at least one environmental, data or IT related science discipline and have dedicated experience managing research projects in these areas, including proven ability to manage projects within strict financial and schedule constraints. You will demonstrate strong leadership skills with the ability to motivate and develop others effectively, having previously managed multidisciplinary teams, sub-contractors or external project partners.It is also desirable but not essential if you have:• Experience of managing projects funded by the Research Councils, the European Commission (e.g. H2020)• Experience of developing work breakdown and cost breakdown structures.• Experience of proposal writing.• Active membership of the Association of Project Management (APM), Project Management Institute (PMI) or other internationally recognized project management organization• Recognized project management qualification, such as APMP (IPMA Level D) / Practitioner Qualification (IPMA Level C), or CAPM / PMP (PMI). To ApplyApplicants are required to include a cover letter outlining their suitability for this role. Please also state where you saw this role advertised.Applications are handled by UK SBS; to apply please click the apply button. Applicants who are unable to apply online should contact us by telephone on +44 (0)1793 867000.The closing date for applications is 24th June 2019.

8476| UKRI Medical Research Council, Laboratory of Molecular Biology| Investigator Scientist - Structural Studies - Dr Madan Mohan - LMB 1079| Investigator Scientist – Structural StudiesStarting Salary £30,914 - £33,755 per annumBand Salary £30,914 - £39,381 per annumMRC Laboratory of Molecular Biology, Cambridge UKWe have a research scientist position available (to be filled as soon as possible) for an experienced and highly motivated individual in the group of Dr. M. Madan Babu at the MRC Laboratory of Molecular Biology in Cambridge, UK. We are looking for a research scientist to assist other members in the group in a programme aimed at understanding the principles of how disordered regions contribute to function. Specifically, the person will provide core support and help other scientists in research aimed at investigating how disordered regions drive the formation of protein assemblies, modulate protein stability and transcription initiation. The ideal candidate will have a Ph.D. and extensive lab experience in yeast molecular biology, genetics and genomics. Experience with handling DNA sequence libraries, library cloning and next generation sequencing is essential. You will enjoy a rich and collaborative intellectual environment and interactions with a dynamic interdisciplinary team working on a variety topics, both computational and experimental.The MRC Laboratory of Molecular Biology is a research institute within UK Research and Innovation (UKRI). UKRI is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at www.ukri.org.Working for UKRI MRC provides a whole host of benefits including a defined benefit pension scheme, excellent holiday entitlement and Benenden Healthcare membership. You will also have access to employee shopping/travel discounts, on site sport and social facilities, as well as salary sacrifice cycle to work schemes and childcare vouchers.To apply and access full details of the vacancy please visit our job board at https://mrc.tal.net/vx/lang-en-GB/appcentre-1/tmpwid-7c20_1d396251-2252-4867-8a5b-3b9423c960ff/candidate/postings/1208 If you are unable to apply online please contact us at [email protected] date: 12 June 2019Final appointments will be subject to a pre-employment screening.The Medical Research Council is an Equal Opportunities Employer who participates in the Disability Confident scheme

8494| University of Otago, Department of Pathology| Research Fellow - Pathology| DEPARTMENT OF PATHOLOGYDUNEDIN SCHOOL OF MEDICINEWho we are:The Developmental Genetics & Pathology laboratory team is focused on aberrant developmental mechanisms of disease, particularly cancer. The team comprises four research fellows, two assistant research fellows (including a bioinformatician), five postgraduate students, and an intern, housed within a well-equipped research laboratory, and using state-of-the art advanced methodologies. The research team has a well-established international profile.The Role:As a Research Fellow based within our department you will be part of the team working on the project ‘Epigenomic profiling to predict patient response to melanoma immunotherapy’.Some key tasks include:• Collecting samples for discovery cohorts.• Carrying out sequencing-based analysis of genome-wide methylation landscapes of responding and non-responding patients.• Investigating mutational profiles of responding and non-responding patients.• Developing Sequenom assays for methylation biomarkers identified in responding and non-responding patients.• Carrying out gene expression analysis of biomarker regions of interest in the validation cohort.• Contributing to the development and dissemination of research tools for genome-wide and epigenome-wide analysis for the Eccles laboratory group, including for CancerHub.Your Skills and Experience:• PhD in relevant field.• Experience in identifying blood-based biomarkers.• Experience with epigenetic analysis and large-scale/integrated bioinformatic analysis.• Organised, methodical, with excellent attention to detail.• Ability to work as a team member and to interact well with a range of staff and health professionals, and to perform tasks with minimal supervision.Further Details: Position 1901102This is a full-time, fixed term position for four years and is available immediately.Specific enquiries may be directed to Professor Michael Eccles, via the contact details attached.

8478| The University of Nottingham, Mechanical, Materials and Manufacturing Engineering| Postdoctoral Research Associate in Composite Structures and Metamaterials Modelling and Health Monitoring| The University of Nottingham is a world leader in aerospace R&D. With a research income which exceeds £120M per Year, the Engineering Research Power of the University currently ranks 4th in the UK. The Faculty of Engineering is ranked in the top 5 out of 85 engineering departments in the UK in the last Research Assessment Exercise, with most of its research output classified as world leading or internationally excellent in quality. It provides state-of-the art experimental and computational facilities and attracts leading scholars from around the world, many of whom are leaders in their fields.Project description: Failure of aerospace composite structures can be life threatening for passengers and financially catastrophic for the operator and the manufacturer. This is the main reason for which a large part of an aircraft’s lifecycle and operating cost is spent for inspecting its structural integrity on the ground. On-line detection and characterization of minor failures within composite aerospace structures can lead to a radical reduction of this cost. Applications are invited for a full-time Postdoctoral Research Associate post within the Composites Group of the University. A fixed-term 24 month contract will be offered to the successful candidate. Remuneration will depend on previous experience.The successful candidate will be expected to make significant contributions to the development of multiscale and wave propagation modelling tools as well as robust damage identification tools for industrial composites and metamaterials. Applicants should be able to demonstrate a consistent publication track record in the areas of numerical modelling and/or composite structures.This funding call is open to all UK, EU and International applicants.Enquiries prior to making an application may be addressed along with a detailed CV to Dr D. Chronopoulos [email protected] This position will remain open until filled.

8475| University of Exeter, College of Life and Environmental Sciences| College of Life and Environmental Sciences, Biosciences Postdoctoral Research Fellow| The above full-time post is available from 1/7/19 to 30/6/23 in the College of Life and Environmental Sciences on a fixed term basis.This project has received funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (grant agreement No. 646625.The post:The College wishes to recruit a Postdoctoral Research Fellow to participate in a high profile ERC funded project entitled 'Understanding and exploiting the P450 insect resistome' and then subsequently a BBSRC project entitled 'The adaptive potential of clonality in aphid crop pests'. This post is available for four years from July 2019. The post-holder will be based in the Bass lab and be part of a thriving group comprising several PhD students, post-doctoral research fellows and technicians.About the role:Both projects focus on different aspects of the evolution of insect resistance to natural and synthetic toxins. We will use a range of genomic, transcriptomic and epigenetic approaches to understand the (epi)genetic mechanisms that allow clonally reproducing insects to adapt to sudden environmental change (such as that imposed by pesticides) in the absence of sexual reproduction.The successful applicant will employ a range of bioinformatic and molecular approaches to investigate this topic. Their primary role will be to generate and analyse next generation sequence data, including resequenced insect genomes, transcriptomes and whole genome bisulfite sequencing (WGBS) data. The fellow may also conduct, orcontribute to, follow-on work to functionally validate the role of candidateresistance genes.Over the duration of the project, the postdoc will be encouraged to develop their own avenues of research with a view to establishing themselves as an independent investigator. The project includes substantial funds for sequencing, research consumables, and to facilitate attendance at national and international conferences/workshops.About you:Applicants will possess a relevant PhD or equivalent qualification/experience in a related field of study. Experience working with genomic data and bioinformatics skills are essential. Experience with standard molecular biology methods and post-genomic functional approaches would be advantageous.You can view the Job Description and Person Specification document here.For further information please contact Professor Chris Bass, e-mail [email protected] University of ExeterWe are a member of the prestigious Russell Group of research-intensive universities and in the top 150 universities in the world (Times Higher Education World University Rankings 2019). We combine world-class teaching with world-class research, achieving a Gold rating in the Teaching Excellence Framework Award 2017.Our research income in recent years means we're fastest growing UK Research University and we seek to answer some of the most fundamental issues facing humankind today through this. 98% of our research is international quality (2014 Research Excellence Framework) and we encourage proactive engagement with industry, business and community partners to enhance the impact of research and education and improve the employability of our students. Benefits:We offer some fantastic benefits including:- 41 days leave per year- Options for flexible working- Numerous discounts at leading retailers- Onsite gyms on all of our campus' and a cycle to work scheme- Sector leading policies around maternity, adoption and shared parental leave (up to 26 weeks full pay), paternity leave(up to six weeks full pay) and a new Fertility Treatment Policy- Stunning campus environments in Exeter and Cornwall, in the beautiful South West of EnglandTo apply, please visit: https://jobs.exeter.ac.uk/hrpr_webrecruitment/wrd/run/ETREC107GF.open?VACANCY_ID%3d366021Og93%1BUSESSION=6F6FD48AC2C04751B753C70CE85D0511&WVID=3817591jNg&LANG=USAWith over 22,000 students and 5,500 staff from 180 different countries we offer a diverse and engaging environment in which to work. We are an equal opportunity employer, a Disability Confident employer and an Athena Swan accredited institution. Whilst all applicants will be judged on merit alone, we particularly welcome applications from groups currently underrepresented in the workforce. The closing date for completed applications is 12 Midnight, Monday 27th May 2019. Interviews are expected to take place in June.

8501| Institute of Cancer Research, Structural Biology| Postdoctoral Research Fellow in Cancer Biology| Funded by a 6-year Programme Foundation Award from Cancer Research UK, a post-doctoral position is available immediately in the laboratory of Dr. Alessandro Vannini, Division of Structural Biology at The Institute of Cancer Research in London. We are looking for highly motivated and creative individuals with a strong interest in cancer biology. We currently employ molecular and cell biology approaches in vitro and in vivo, to elucidate the role of the RNA Polymerase III transcription apparatus in cancer.This is an ideal opportunity for a committed and enthusiastic scientist to join a dynamic research team with excellent collaborators and facilities. The Postdoctoral Researcher will work independently and will have the opportunity to supervise a higher scientific officer in order to establish a comprehensive research plan aimed at uncovering RNA Polymerase III role in cancer and exploit its therapeutic potential (see for example “Gouge et al., Cell 2015”).Applicants should possess a PhD (or equivalent) in in cell biology or related disciplines and should be familiar with multiple of the following techniques: functional genomics via next generation sequencing, genome editing with CRISPR, 3D cell culture and tissue culture/engineering.Appointment will be on Fixed Term Contract for 3 years in the first instance, with a starting salary in the range of £31,023 to £38,135 p.a. inclusive (based on previous post-doctoral experience).Informal enquiries are welcome and can be made to Dr. Alessandro Vannini ([email protected]). Please note, this address is for enquiries only and you should not send your application to this email address.Application form, CV and supporting statement must be submitted online at http://www.icr.ac.uk/jobsearchVacancy ref 741

8502| Invicro| Senior Study Manager| This is an exciting opportunity to work as a Senior Study Manager within the Discovery Research (DR) group at Invicro (based in London). We are seeking a Study Manager with clinical or pre-clinical imaging research experience to manage all internal aspects of projects with our Discovery Research group. The individual should enjoy challenging and analytical work and be motivated by the idea that together we can accomplish great things and make a positive contribution to society through our mission.The RoleThe Senior Study Manager is responsible for managing the organization and reporting of pre-clinical imaging studies within the Discovery Research department as well as assisting with business development activities such as study pricing and quote generation.Key responsibilities include:Organisation and oversight of data acquisition, reporting, and preparation of scientific presentations / interpretation of results for a given studyWorking closely with the Analysis team to ensure that all desired deliverables are generated in a scientifically-relevant form, acceptable to send to the customer, and goals of a given study are clearly addressedAccountability for the accuracy of all data in a study and compilation/posting of study documentationOversight and management of project timelines and progress while working closely with Operations and Imaging Scientists to interface with customers and subcontractors on oversight of project financesFunction as a representative of the Discovery Research department within Invicro and maintain a positive attitude in interactions with all involved in a study, while focusing on collaborative problem-solving.The CandidateThe ideal candidate will have experience with pre-clinical in vivo imaging techniques including understanding of theory, familiarity with data acquisition and analysis techniques, and experience in quality control and presentation of such data. The candidate should demonstrate the ability to manage multiple projects at once. The candidate must be able to work quickly and accurately and pay strict attention to detail. They must be adaptable and capable of working and leading in a team environment. In addition, they must be able to professionally and confidently interact with customers and subcontractors, as well as prepare and deliver written summaries of work. They will be highly motivated and able to deliver to defined timelines, in collaboration with colleagues from the preclinical sciences and image analysis groups.To be considered for this position, you will have:• PhD with applicable experience; Technical Masters with 4+ years applicable industry experience or equivalent; Technical Bachelors with 6+ years applicable industry experience (e.g. engineering, physics, chemistry or biology)• Previous biomedical research experience• Excellent communication skills• Superior time- and project-management skills• Ability to work quickly with strict attention to detail• Past leadership experience in a team environment• Adaptable, able to professionally and confidently interact with teammates and subcontractors and deliver written summaries of work• Basic understanding of (or past exposure to) small molecule radiochemistry and/or radio- or fluorescent labeling of proteins and/or MRI, PET, SPECT, or CTCompetitive Salary & Benefits Contributory Pension, Bonus, Private Medical Insurance, Life Assurance & Flexible Benefits options.To apply for this position please forward your CV and a covering letter detailing your relevant experience to [email protected] We ensure compliance with Data Protection laws and you can find our Privacy Notice on the Invicro IntranetInvicro is an equal opportunities employer and positively encourages applications from suitably qualified and eligible candidates regardless of sex, race, disability, age, sexual orientation, gender reassignment, religion or belief, marital status, or pregnancy and maternity.

8470| University College London, Department of Chemistry| Research Fellow in Virtual Human Blood Flow Simulation| The successful candidate will join a very active inter-disciplinary group in the Centre for Computational Science, and will work on the development and deployment of medical and clinical applications of the lattice-Boltzmann method for blood flow. The postholder will work primarily on scientific applications of HemeLB, a flexible lattice-Boltzmann code for the simulation of blood flow, at the scale of the entire human body, in support of medical and clinical decision making and for physiological research. The postholder will be expected to engage closely in the development of software within the project, and with the verification and validation of the methods being deployed, in order to facilitate uptake of HemeLB within the context of CompBioMed. The post is funded by the European Commission and is available immediately, for a period of 24 months initially. A PhD (or near to being awarded a PhD) degree—involving a substantial high-performance computing component—in physics, computer science, computer engineering, applied mathematics or chemistry, with experience in the lattice-Boltzmann method, is an essential requirement. Experience in high performance computing is also essential, alongside a proven ability to programme quickly and effectively in state-of-the-art high-performance computing environments. Please note, appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, appointment will be at Research Assistant Grade 6B (salary £30,922 - £32,607 per annum, including London Allowance of £3,092 p.a).For further details about the vacancy and how to apply online please go to: https://www.ucl.ac.uk/human-resources/working-ucl/jobs-ucl and search on Reference Number 1802717. Please include a publication list along with CV. Informal enquiries should be addressed to Prof Peter Coveney ( [email protected] ). Any queries on the application process can be directed to Judith James – [email protected] Date: 26/5/2019Latest time for the submission of applications: 23:59.Interview Date: TBCWe particularly welcome female applicants and those from an ethnic minority, as they are under-represented within UCL at this level. Our department holds an Athena SWAN Bronze award, in recognition of our commitment to advancing gender equality.To apply click here: https://atsv7.wcn.co.uk/search_engine/jobs.cgi?owner=5041178&ownertype=fair&jcode=1802717

8498| University of Cambridge, MRC Mitochondrial Biology Unit| Research Associate (Fixed Term)| Department/Location: MRC Mitochondrial Biology UnitSalary: £32,236-£39,609Reference: SM19126The University of Cambridge wishes to appoint a Postdoctoral scientist to join the research group of Dr Edmund Kunji in the MRC Mitochondrial Biology Unit of the University of Cambridge.The postholder will work within a programme focussed on mitochondrial transporters. Transport processes are crucial for the functioning of mitochondria and mutations in transport proteins cause of a wide range of metabolic, neuromuscular and developmental diseases. Basic molecular understanding of their structure and mechanism is required to understand their role in health and disease.The goal of the project is to study their structures in different conformational states by electron cryo-microscopy and/or x-ray crystallography. The post-holder will participate in every stage of the process, from the generation of expression strains or cell lines, isolation of mitochondria, purification and sample preparation, data acquisition and processing, and structure model building and interpretation. There will also be an opportunity to study their role and mechanism using a wide range of biochemical and biophysical techniques. This project is part of a collaborative SNF Sinergia grant together with Profs. Hediger and Lochner of the University of Bern.Candidates will have a PhD in Structural Biology/Biophysics or related disciplines, and a track record of research achievements. Knowledge of protein purification and experience in structural biology are essential.The MRC Mitochondrial Biology Unit is a world-renowned centre for mitochondrial research. Additional information can be found at http://www.mrc-mbu.cam.ac.uk/ Fixed-term: The funds for this post are available for 3 years in the first instance.To apply online for this vacancy and to view further information about the role, please visit: http://www.jobs.cam.ac.uk/job/21519/ The closing date for applications is Wednesday 12th June 2019 with interview date yet to be confirmed.Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.Please include details of your referees, including e-mail address and phone number, one of which must be your most recent line manager.Please quote reference SM19126 on your application and in any correspondence about this vacancy.The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

8493| Medical Research Council, MRC London Institute of Medical Sciences| MRC Post Doctoral Research Scientist| MRC Postdoctoral Research ScientistFixed-term, 2 years initially£35,859 - £38,700 pa inclusive*London, UKApplications are invited for a 2-year postdoctoral research position in the Reprogramming and Chromatin Group headed by Professor Petra Hajkova at the MRC London Institute of Medical Sciences. The group studies molecular mechanisms underlying epigenetic reprogramming in vivo and in vitro (for further information please visit https://lms.mrc.ac.uk/research-group/reprogramming-and-chromatin/).We are looking for a passionate scientist to join our efforts to elucidate molecular mechanisms implicated in the erasure of epigenetic memory (at both DNA methylation and chromatin structure levels) observed in early mouse embryo and in developing germ line. For our recent publications please see (Nashun et al, Mol Cell 2015, Amouroux et al, Nat Cell Biology 2016 and Hill et al, Nature 2018). You will need a PhD or equivalent experience in a relevant area and proven experience in the field of epigenetics and chromatin.The London Institute of Medical Sciences is an Institute funded by the MRC and is a Division of the Faculty of Medicine, Imperial College. Based on the Hammersmith Hospital Campus in West London (W12), the LMS has first class facilities and provides investigators from clinical and basic science backgrounds with the opportunity to pursue innovative, multidisciplinary research within the established clinical base of Imperial College. For more information, visit www.lms.mrc.ac.uk.This post is a MRC Postdoctoral Scientist to support post-doctoral training and help establish successful research scientists in their chosen field. During the fellowship tenure we are committed to provide mentorship for career development and improvement of communication skills. We offer a highly attractive benefits package including competitive salary, excellent holiday entitlement and generous pension scheme. The MRC London Institute of Medical Sciences is a research institute within UK Research andInnovation. UK Research and Innovation is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at www.ukri.org For full details of this post and to complete an online application, visit https://mrc.tal.net/vx/lang-en-GB/appcentre-1/candidate/postings/1212 and upload your CV, names and contacts of two scientific references along with a covering letter stating why you are applying for this role (providing evidence against the requirements of the job as per the job description and person specification). Please quote reference number LMS – 1082.Closing date: 12 June 2019*Salary quoted is inclusive of London weighting. Additional allowances comprise a £1,000 lump sum Settlement Allowance plus a yearly Training Allowance of £850 in the first year, paid in monthly installments. The Training Allowance increases to £1,300 in year two.

8472| Ghent University, Mechanics of Materials and Structures| Postdoctoral vacancy (3 years) on design and finite element modelling of 3D printed orthoses and prostheses| 3D printing or Additive Manufacturing (AM) technologies carry the promise of revolutionizing the quality and efficiency of healthcare. However, the required technologies, even when available, are currently too fragmented to be integrated into routine, affordable and streamlined solutions that can benefit a large number of patients. The challenge thereby is to deliver 3D printing technologies that enable:Patient-specific solutions: personalized medical devices that are designed using the images acquired for individual patients and best fit their treatment needs;Complexity and miniaturization: complex shapes, articulations and miniaturized geometries of orthotics/prosthetics and instruments have the potential to radically enhance treatment effectiveness and post-treatment recovery;Streamlined care: the ability to integrate diagnosis, design and manufacturing of AM medical devices into a validated software platform is the key to delivering fast, affordable treatments with dramatic life-saving potential.The INTERREG project 3DMed aims to improve affordability and large-scale accessibility of medical treatment using 3D printed devices. This will be achieved by increasing the Technology Readiness Level (TRL) of state-of-the-art 3D printing technologies for medical applications and integrating them into a streamlined, fast, cost-effective software platform for use in routine clinical practice. This project contains 17 partners from The Netherlands, Belgium, France and United Kingdom, including universities, hospitals, software suppliers, 3D printing companies, clinical observers, manufacturers of medical devices and implants,... The project is coordinated by TUDelft.In this Postdoctoral position, it is the purpose to develop patient-specific design and finite element modelling of 3D printed orthoses and prostheses (an orthosis is an externally applied device used to modify the structural and functional characteristics of the neuromuscular and skeletal system, while a prosthesis an artificial device replaces a missing body part). This position requires an in-depth knowledge of advanced design, finite element modelling and topology optimization, based on the processing and segmentation of patient-specific medical images. Important criteria that will be investigated, are: (i) stress limits for a fatigue-safe design (under multi-axial loading); (ii) critical stress concentrations due to certain geometrical discontinuities; (iii) stiffness match (or mismatch) with surrounding body parts; (iv) thermal behaviour of the part at body temperature. Different orthoses and prostheses will be covered and a close collaboration will be required with the researchers at TUDelft, clinical observers, AM service providers and software companies.Only candidates with a PhD degree or equivalent experience should apply. The candidate should have a strong background in design and FE modelling for medical applications. He/she will closely work together with the other postdoc in the team (see other vacancy) and is willing to travel frequently to meet and discuss with the other project partners in the neighbouring countries.More information can be found on:http://www.composites.ugent.be/PhD_job_vacancies_PhD_job_positions_composites.html

8508| University College London| Research Fellow - Bioinformatics - Cancer Genome Evolution Scientist, - Ref: 1805885| We are seeking a full time Research Fellow to work on evolutionary cancer genomics. The successful candidate will make use of multiple ‘omics data from the longitudinal prospective cohort study TRACERx, in order to map tumour evolution, and obtain a deeper understanding of the interface between cancer evolution and the immune microenvironment. The candidate will be based within the McGranahan Lab within the UCL Cancer Institute and the CRUK Lung Cancer Centre of Excellence. The posts are funded for one year in the first instance with a start date of as soon as possible. The successful candidate must have, or be studying towards, a PhD. They must provide previous experience with NGS data as well as fluent in R, Python, Perl or C ++, have good knowledge of statistics and be able to present complex data at meetings. Appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at research assistant Grade 6B (salary £30,922 - £32,607 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis. For further details about the vacancy and how to apply online please go to: https://www.ucl.ac.uk/human-resources/working-ucl/jobs-ucl and search on Reference Number 1805885. For enquiries regarding the application process please contact Cancer Institute HR Office [email protected] Closing Date: 30 May 2019Latest time for the submission of applications: 23:59.Interview Date: TBCUCL Taking Action for EqualityOur department holds an Athena SWAN Silver award, in recognition of our commitment and demonstrable impact in advancing gender equality.To apply click here: https://atsv7.wcn.co.uk/search_engine/jobs.cgi?owner=5041178&ownertype=fair&jcode=1805885

8499| Liverpool School of Tropical Medicine, Department of Vector Biology| Post-Doctoral Research Associate| Founded in 1898 and the oldest of its kind in the world, the Liverpool School of Tropical Medicine (LSTM) is an internationally recognised centre of excellence for teaching and research in tropical diseases. Through the creation of effective links with governments, NGOs, private organisations and global institutions and by responding to the health needs of communities, LSTM aims to promote improved health, particularly for people of the less developed/resource poorest countries in the tropics and sub-tropics.The Department of Vector Biology at LSTM is an international leader in the study of insect disease vector biology, and at the forefront in developing novel strategies for vector control, particularly the management of insecticide resistance. Vector Biology Department has recently established a research group based at the Malawi-Liverpool-Wellcome Trust Clinical Research Programme (MLW) in Blantyre, Malawi. The purpose of the group is to encourage new developments in vector research related to the monitoring and control of vector-borne diseases. Led by Christopher Jones, the group has acquired funding to modify and apply a quantitative model – previously developed for tracking midge-borne infections in Europe – to determine the influence of wind patterns on mosquito movement and malaria infection. The research team is currently recruiting for a Post-Doctoral Research Associate to implement a field study to quantify mosquito dispersal and contribute to the development of the model for the mosquito-malaria system. This is an interesting opportunity for a highly motivated and experienced entomologist/biologist with interest in ecological modelling to join a large and diverse team of Vector Biologists with an extensive network of collaborators. To apply, you must hold a PhD in Biology and/or Ecology or related science with a strong quantitative component and possess excellent knowledge of conducting scientific literature searches and using R-cran statistical software. Evident experience of field work in malaria endemic countries coupled with the ability to synthesise and critically appraise large volumes of scientific literature and adapt to working in varying environments is crucial to the post. Well-developed skills in the areas of research, communication and problem solving is essential to your success. Knowledge and experience in mosquito vector behaviour, inferential methods and stochastic analyses and handling insects and entomological trapping devices, will be advantageous to your application.Please note that for the duration of the contract, the post will be based between LSTM (Liverpool), Lancaster and Malawi. The successful post holder will be encouraged and supported to apply for independent fellowships and will also be provided strong mentorship and guidance for such applications.Closing Date: 2nd June 2019Take a look at some of the great work we have achieved over the past year 2017-2018 by viewing our annual report: https://www.lstmed.ac.uk/about/publications/lstm-annual-report-2017-2018 This job is unlikely to attract a Tier 2 Certificate of Sponsorship (formerly a work permit). Applications from candidates who require Tier 2 immigration status to work in the UK may not be considered if there are a sufficient number of other suitable candidates. To apply for a Tier 2 Certificate of Sponsorship, employers need to demonstrate that they are unable to recruit a resident worker before recruiting an individual overseas. For further information, please visit: https://www.gov.uk/government/organisations/uk-visas-and-immigrationWe believe that this post will not be suitable for individuals on Tier 5 visas as these posts are not considered to be supernumerary to the organisation. For further details, please visit the UKVI website: https://www.gov.uk/browse/visas-immigration/work-visas LSTM actively promotes Equal Opportunities and Safeguarding Policies

8473| Queen Mary University of London, School of Economics and Finance| Marie Skłodowska-Curie Individual Fellowships (2019 Call) European Commission H2020 Funding Opportunity (MSCA-IF-2019)| The School of Economics and Finance at QMUL welcomes expressions of interest by postdoctoral researchers of any nationality, to apply jointly with a QMUL host supervisor to the EC Marie Skłodowska-Curie Individual European Fellowship Scheme under the 2019 call. The Fellowship is a prestigious European funding scheme that supports mobility, career development, and training within and beyond Europe, and offers 12 to 24 months’ highly competitive salary, a mobility allowance, family allowance and research funds.Full details of the Scheme and application process can be found at:https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/msca-if-2019The call is now open, the final deadline date for applications to the European Commission is 11 September 2019. Applicants will need to submit an EOI to QMUL by 3 June 2019, please see the ‘How to Apply’ section for more details.How the fellowship worksA postdoctoral researcher (fellow) with a minimum of PhD level experience moves to an institution in another country (host), where he or she works with a supervisor to deliver a specific project involving research, innovation, training and networking activities. Both parties must collaborate on the application and the supervisor should offer appropriate supervision and support. Regular meetings between the supervisor and the researcher are essential for the planning and implementation of the research and innovation plan.Proposals should be built around a plan for training-through-research at the host organisation (Career Development Plan). In addition to research activities and objectives, this should address the researcher's training and career needs, including training on transferable skills, planning for publications and participation in conferences.What funding the fellowship offers12-24 months' full-time research funding. The funding covers:• Gross salary (€89,067 pa*, including Living Allowance and Mobility Allowance)• Family allowance (€500 per month, if eligible also paid as salary to fellow) • Research, training and networking costs (€800 per month)• Management and indirect costs (€650 per month to the host)*Note that gross salary includes employer on-costsAll allowances are flat rate, calculated according to the duration (number of months) of the fellowship. Research AreasYou have free choice of research field within Economics and Finance. However, below are details of the School’s research groups for information:Applied MicroeconomicsEconometricsFinanceMacroeconomicsMicroeconomic TheoryEligibilityThere are two main requirements:• you must hold a PhD (or equivalent), or have four years full time research experience by the call deadline of 11 September 2019.• you must not have lived or worked in the UK for more than 12 months during the three years up to the closing date of the call (11 September 2019). How to ApplyPlease submit your EOI pack to Nick Owen, Research Manager, [email protected], tel. +44 (0)20 7882 7298 by Monday 3 June, 2019. Expressions of Interest should consist of the following documentation, submitted in one PDF file:• Cover letter (max one page)• A copy of your CV• A 3-page research proposal summaryThe School aim to select candidates that it wishes to support for the Fellowship by 7 June 2019. Selected candidates will then be invited to prepare their full proposal with their proposed supervisor(s). If you are invited to submit a full proposal, please Read the Guide for Applicants and call text. Assistance with regards to proposal development and submission will also be provided by the QMUL Joint Research Management Office, EU Unit.