8120| Sidney Kimmel Cancer Center/Thomas Jefferson University, Department of Cancer Biology| Postdoctoral Researcher in Ras-tumor biology| We are currently seeking highly motivated and independent postdocs to study how oncogenic RAS signaling cooperates with stress stimuli to promote tumorigenesis. The lab has recently described that cancers that are driven by the mutated KRAS gene can mobilize a stress protective response through the engagement of the stress-sensing machinery known as stress granules. The successful candidate will utilize 2D and 3D cell culture, mouse models, high-resolution/high-content microscopy, biochemistry and molecular biology to decipher the molecular networks through which stress granules determine the capacity of mutant KRAS cells to cope with stress, and their role in KRAS-driven pancreatic cancer and the establishment of a tumor-promoting microenvironment. For further information please visit www.grabockalab.comRequirementsCandidates should have a recent PhD or MD/PhD degree in cancer biology, cell biology, biochemistry, or a closely related field, have proven ability to work independently as well as within a team, be able to multi-task, and communicate effectively. Only candidates with first author publications from their terminal degree will be considered.Interested applicants should submit a cover letter explaining their scientific interest, their previous experience, and a CV to Dr. Elda Grabocka at [email protected] The last page of the CV should include the contact information (e-mail address and phone number) for three references.

8134| University College Dublin, UCD School of Medicine| UCD Post-doctoral Research Fellow Level 1, UCD School of Medicine (Temporary)| Applications are invited for a Post- Doctoral Research Fellow Level 1 in the UCD School of Medicine. This is a temporary post.Dr Lynne O’Shea and her research group are focused on providing a molecular understanding of the factors affecting fertility. With a special interest in basic science, current research projects range from oocyte and follicle development to fertility preservation in women. With this project Dr O’Shea is leading the clinical validation of novel biomarkers of oocyte quality; with the potential to improve pregnancy rates following assisted reproduction.See Job Description for more details.Salary: €37,222 per annum.Appointment on the above range will be dependent upon qualifications and experience.Closing Date: 17.00hrs (Local Irish Time) on 5th November 2018.Applications must be submitted by the closing date and time specified. Any applications which are still in progress at the closing time of 17:00hrs (Local Irish Time) on the specified closing date will be cancelled automatically by the system. UCD are unable to accept late applications.UCD do not require assistance from Recruitment Agencies. Any CVs submitted by Recruitment Agencies will be returned.Prior to application, further information (including application procedure) should be obtained from the Work at UCD website: https://www.ucd.ie/workatucd/jobs/.

8133| University of Huddersfield, Computing & Engineering| Research Fellow| Fixed term appointment for 30 months, 37 hours per week Ref: R3952The School of Computing and Engineering is seeking to recruit a suitably qualified Research Fellow in computer science. This is a research post funded by the EPSRC UKRI Innovation Fellowship: A semantic infrastructure for advanced manufacturing (EP/S001328/1). The research theme is to build a novel semantic infrastructure for advanced manufacturing, by supporting knowledge representation, interrogation, reasoning and exchange for smart design, manufacturing and measurement of advanced products. The focus will be on the development of a toolbox to formalise knowledge in/between design, manufacturing and measurement, especially for additive manufacturing (AM).The person appointed will have a PhD in computer science-related subjects. The appointee will have a comprehensive background in the research field of knowledge management, and demonstrate an awareness of the current state of knowledge representation languages. Strong knowledge in informatics and practical experience in the development of software systems are key requirements. The appointee must also have advanced level of programming skills, including at least one or more of the following programming languages: Java, C++, C#, Scala, Haskell and Python.Candidates should have a good recent record of publication in high quality journals and be capable of developing research objectives, projects and proposals, undertaking research and evaluating outcomes independently. Candidates must also show a good experience on team work and communications for the sponsored post. The role will be required to undertake supervision of post-graduate research students, organisation of technical, progress and planning meetings. Candidates will be expected to generate high quality publications.For further details about this post and to make an application please visit http://hud.ac/er4 Closing Date: 5 November 2018Interview Date: 3 December 2018Working for Equal Opportunities.Innovative University. Inspiring Employer.

8122| University of Southampton, Ecology and Evolution| Research Fellow in Evolutionary Genomics| Location: Highfield CampusSalary: £30,395 to £31,302 Full Time Fixed Term (3 years)Closing Date: Friday 02 November 2018Reference: 1064218BJWe seek a Research Fellow to investigate “The contribution of plasticity to adaptive divergence: domestication as a model”. The NERC/BBSRC co-funded project provides support for 3 years from 7th January 2019 to work with Dr Mark Chapman in the Ecology and Evolution group at the University of Southampton (https://www.southampton.ac.uk/biosci/about/staff/mc1c12.page), co-supervised by Dr Tom Ezard in Ocean and Earth Science (https://www.southampton.ac.uk/oes/about/staff/te1e12.page).The goal of this project is to study the evolution of plasticity, comparing crops to their wild relatives, as a model for understanding the genetic basis and role of plasticity in adaptive divergence and the early emergence of new taxa.You will have a PhD* or equivalent professional qualification in a relevant subject area, with a strong evolutionary and genomic/transcriptomic component. A high level of competence in bioinformatics is required, with relevant experience demonstrated by publications in peer reviewed journals where possible. Competency in statistics and programming would be advantageous and experience with plants desirable. You should be a highly motivated scientist, capable of contributing to developing your own research project, a good team worker and an excellent communicator.Chapman and Ezard are interested in fusing evolutionary theory with experimental approaches, and you would be expected to contribute intellectually to the development of the project. A broad interest in evolution as a whole is required. The current work will use extensive greenhouse and laboratory experiments coupled with transcriptome, whole genome and methylome analyses to decipher the contribution of plasticity to adaptive divergence. It offers excellent potential for publishing in high impact journals and developing independent research agendas.You will assume leadership on the project, including significant intellectual contribution, setting up experiments and involvement in making decisions about current and future research directions. You will work in a highly collaborative atmosphere supported by state-of-the-art research facilities that will provide a perfect environment to carry out the project.For informal enquiries, please email Dr Mark Chapman ([email protected]) in the first instance. *Applications will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification. The title of Research Fellow will be applied upon successful completion of the PhD. Prior to the qualification being awarded the title of Senior Research Assistant will be given.Equal Opportunities and Benefits: Biological Sciences holds an Athena SWAN Silver Award, demonstrating commitment to equal opportunities and gender balance in the workplace. We aim to be an equal opportunities employer and welcome applications from all sections of the community. Please note that applications from agencies will not be accepted.The University of Southampton has a generous maternity policy and onsite childcare facilities; employees are able to participate in the childcare vouchers scheme. Other benefits include state-of-the-art on-campus sports, arts and culture facilities, a full programme of events and a range of staff discounts.Please include a covering letter, full CV and names and contact details for three referees in your application.Application Procedure:You should submit your completed online application form at http://www.jobs.soton.ac.uk/www.jobs.soton.ac.uk. The application deadline will be midnight on the closing date stated above. If you need any assistance, please call Sam Stubbs (Recruitment Team) on +44 (0)23 8059 4046. Please quote reference 1064218BJ on all correspondence.

8117| University College Dublin, UCD School of Computer Science| UCD Post- Doctoral Research Fellow Level 1, UCD School of Computer Science (Temporary)| The postdoctoral researcher will contribute to the development of a suite of intelligent decision support services that will aid agronomists and farmers in the management of their crops. In particular, the researcher will contribute to the research, design and implementation of the CONSUS software and data architecture that will facilitate the integration and seamless interoperability of software components, services and data and will facilitate the transformation of data into knowledge that can be utilised by the decision support services.The software and data architecture will support the harvesting, curation, conflation and access to diverse data together with actuation of data deriving components. This architecture will incorporate IoT (Internet of Things) technologies and will underpin and make provision for Intelligent decision support services offered to the end user.The particular focus of this research post is delivering intelligent decision-support services for both agronomists and farmers offering contextualised/personalised advice and support for what if scenario modelling.The successful candidate will have the opportunity to work in a dynamic research environment and will actively contribute to exciting and cutting-edge multi-disciplinary research. Experience gained in this post will significantly further the career development and training of the successful candidate.Salary: €35,324 per annum.Closing Date: 17.00hrs (Local Irish Time) on 26th October 2018.Applications must be submitted by the closing date and time specified. Any applications which are still in progress at the closing time of 17:00hrs (Local Irish Time) on the specified closing date will be cancelled automatically by the system. UCD are unable to accept late applications.UCD do not require assistance from Recruitment Agencies. Any CVs submitted by Recruitment Agencies will be returned.Prior to application, further information (including application procedure) should be obtained from the Work at UCD website: https://www.ucd.ie/workatucd/jobs/.

8137| University of Otago, Department of Anatomy| Postdoctoral Fellow - Biomaterials and tissue regeneration| The DepartmentThe Department of Anatomy is one of the largest and longest-established departments at the University of Otago. Our staff teach and research a diverse range of exciting topics in the field of biomedical sciences, including neuroscience.The RoleIn this role, you will be responsible for providing assistance with a project aiming to assess the bioactivity of synthetic heparan sulfate molecules to improve tissue repair.Duties will include:• Preparation and biological testing of biomaterials.• In vivo modelling of brain and skin injury.• Behavioural assessments following injury and repair.• Analysis of brain and skin samples.• Statistical analysis of data.• Writing manuscripts reporting on research results for publication in peer-reviewed journals.• Presenting findings at scientific meetings.• Assisting in writing grant applications and pursuing funding opportunities.• Assisting with writing progress reports to the funding organisation.Your Skills and Experience• PhD in an appropriate neuroscience or biological science.• Experience in biomaterial preparation and testing, behavioural assessments, immuocyto/histochemistry and tissue culture.• Evidence of ability to publish.• A thorough approach to laboratory practice, accurate record-keeping, attention to detail and compliance with all regulatory requirements.• Ability to work cooperatively with a wide variety of people within a research environment.• Ability to work without direct supervision, set priorities and allocate own timetable.• Self-motivated, and committed to a research career in the biological sciences. Further detailsThis is a full-time, fixed-term position for 36 months and is available for immediate start.For further information please contact Dr Andrew Clarkson, Department of Anatomy, via the contact details below.ApplicationTo submit your application please click the apply button below. Applications quoting reference number 1801899 will close on Sunday, 4 November 2018.Additional Information Primary Location: NZL-SI-DunedinEmployment Status: Fixed Term Full-timeSalary Level and Range: Postdoctoral Fellow ($75,896)

8114| University of Bath, Computer Science| Research Associate in Visual Computing and Machine Learning| We are looking for highly motivated individual to work on an exciting new collaboration using visual computing and machine learning in the context of digital healthcare. The 'RA Flare Profiler' is an Innovate UK funded project between the University of Bath, Royal United Hospitals Foundation Trust and Living With Ltd to provide transformational new capability to Living With’s existing 'Living With Rheumatoid Arthritis' (LWRA) product. Utilising Machine Learning technologies, the proposed flare profiler will provide a very granular view of a patient's RA profile, based largely on data collected from the patient from the convenience of their own home and comparing it to a wider patient population, significantly reducing the need for hospital-based specialist tests.Flare frequency, duration and severity are key indicators of disease progression in Rheumatoid Arthritis (RA). While undergoing a flare, patients are exposed to systemic inflammation that can be permanently damaging. Current clinical management of RA is based on either pre-scheduled appointments (e.g. at 6, 12 or 18 month intervals) or emergency clinics, with data collection based around these interactions. There is no regular mapping of fluctuations in disease severity, with the unpredictability of acute flare-ups being a key feature of the disease despite as many as 78% of patients recalling flares monthly or more regularly. As such, it remains very difficult to make informed treatment plans, because of the unpredictability of the disease and patients' fluctuating symptoms.The Rheumatoid Arthritis Flare Profiler will allow every Rheumatoid Arthritis patient to receive a more intelligent and personalised treatment plan, based on the early and continuous reporting of their flare up data and its comparison against the aggregated RA profiler model. This will reduce some of the costs associated with an unexpected deterioration in health and wellbeing. It will do this by combining new and existing mobile phone based methods of capturing individual disease activity with advanced artificial intelligence technology to provide a profiling model that can inform treatment planning.You will join the Centre for the Analysis of Motion, Entertainment Research and Applications (CAMERA) is a thriving EPSRC funded research centre based at the University of Bath (Departments of Computer Science and Health). The aim is to create research impact in the areas of Entertainment, Human Performance Enhancement (e.g. Sport and Training) and Assistive Technologies (e.g. Health). CAMERA has several existing world-class partners across Entertainment, Sport and Health, including: The Imaginarium, The Foundy, The Ministry of Defence (MoD), British Maritime Technologies (BMT) and British Skeleton.This is a fixed-term position with an expected duration of up to 15 months.For an informal discussion about the role, please contact Professor Darren Cosker ([email protected]) or Matthew Young ([email protected]).We are working to improve the gender balance within the department’s population and particularly welcome applications from women.Closing date: Sunday 28 October 2018 Interview date: To be confirmed

8099| University of Liège, Department of Urban & Environmental Engineering| Two postdoctoral positions at LEMA ULiege, in the field of transportation engineering| Job posting 1 - Postdoctoral fellowArea of Research: Transportation Engineering – Agent-Based ModellingOverview of the Position:You will be joining the LEMA research group of the University of Liège, co-directed by Professors Mario Cools, Sigrid Reiter and Jacques Teller, as a main contributor to the FEDER project "Wal-e-Cities", which aims at the development of Smart Cities in the Walloon region of Belgium, focusing on the use of innovative (automated) data collection systems as a backbone to support this development. The successful candidate will perform research on the development of a traffic demonstrator, i.e. an agent-based travel demand framework, which explicitly takes into account the accumulation of data through means of ubiquitous sensor networks. We are seeking a single candidate for a 3-year term (starting with a 1-year contract and upon positive evaluation extended with a further 2-year contract). The postdoctoral fellow will have office space in the Sart-Tilman campus of the University of Liège.Description of Duties:The successful candidate will conduct research in the aforementioned "Wal-e-Cities"- project, will be author on journal articles and conference presentations, and coordinate interactions between diverse project team members, and assure the administrative reporting of the project. Required qualifications:• PhD degree in computer sciences, engineering, planning or related field;• Demonstrated experience in quantitative analysis, GIS and network analysis, and travel behaviour modelling;• Excellent programming skills;• Excellent written and oral communication in English;• Excellent personal time management, project management and organizational skills;• Knowledge of French is considered as an asset. Application instructions:All individuals interested in this position must submit a cover letter and short research statement, a CV, and contact info for two references to Mario Cools by the closing date. Please email materials in a single PDF.Supervisors: Professors Jacques Teller and Mario CoolsExpected start date: October, 2018 (with some flexibility) Job posting II - Postdoctoral fellowArea of Research: Transportation Engineering – Transportation PlanningOverview of the Position:You will be joining the LEMA research group of the University of Liège, co-directed by Professors Mario Cools, Sigrid Reiter and Jacques Teller, as a main contributor to the INTERREG EMR Connect, which aims at improving cross-border mobility in the Euregio Meuse-Rhine. The main objectives of the project are:1. Connect academics, students, public authorities and professionals of the mobility sector in the Euregio Meuse-Rhine. This networking is done in collaboration with the University of Hasselt (Hasselt Universiteit) and the University of Aachen (RWTH Aachen).2. Gather information related to passengers' flows of transport in the Euregio Meuse-Rhine.We are seeking a single candidate for a 2-year term. The postdoctoral fellow will have office space in the Sart-Tilman campus of the University of Liège. Description of Duties:The successful candidate will conduct research in the aforementioned "EMR Connect"- project, will be author on journal articles and conference presentations, and coordinate interactions between diverse project team members, and assure the administrative reporting of the project.Required qualifications:• PhD degree in transportation sciences, (business) economics, geography, computer sciences, business economics), engineering, planning or related field;• Demonstrated experience in quantitative analysis, GIS and network analysis, and/or travel behaviour modelling;• Excellent written and oral communication in English;• Excellent personal time management, project management and organizational skills;• Knowledge of French is considered as an asset. Application instructions:All individuals interested in this position must submit a cover letter and short research statement, a CV, and contact info for two references to Mario Cools by the closing date. Please email materials in a single PDF.Closing date: Screening of applications will commence on September 20th and continue until the position is filled.Supervisors: Professor Mario CoolsExpected start date: October, 2018 (with some flexibility)

8139| The Health Concierge/ University of Westminster, School of Life Sciences| Research Fellow in Mitochondrial Bioenergetic Index| 12 MONTHS, FIXED TERMSalary Negotiable for Correct Candidate The role: It is now possible to collect a small volume of blood from subjects and assess basal mitochondrial function in the form of a mitochondrial bioenergetic health Index (MBHI) and subsequently determine how it varies in response to different life-style conditions. The aim of this project is for the Research Fellow to implement this MBHI to monitor changes in bioenergetics in free-living individuals. This, coupled with other risk markers, will enable us to stratify subjects against a population’s optimal health curve, and thus provide them with a measurable point on a scale. It will be a benchmark for each individual to work from, in order to achieve or maintain optimal health. The ultimate aim is to create a novel data management system that will integrate current and future health outputs that are presently collected and presented individually to customers.Responsibilities:Developing and implementing the MBHI. You will, in conjunction with Prof Bell, design and carry out the experiments, analyse results and create Standard MBHI Curves.Work closely with all stakeholders to maximise the impact of the results and integrate them into practical data management systemCollating, presenting and producing project updates/reports to SME stakeholders and colleagues Support the SME for knowledge transfer with project updates and maintenance/support documentation/videos.Essential criteria: Minimum 2.1 BSc in biochemistry or related subject and experience in:Isolation of PBMC and mitochondria Assessing mitochondrial function Use of SeaHorse system Participant recruitmentUnderstanding of research method, analysis and interpretation of resultsCreation of practical and ease of use of Data Bases and ModellingAbility to:Communicate well to non-specialist audience Work well under pressure Desirable criteria:PhD with experience in mitochondrial metabolism and cell biologyKnowledge of programming as you will be working closely with the SME to implement the use of “personalised avatars” for visualization of health outputSome expertise in “R” or “Python” for statistical analysisAbout KEEP+:This post forms an integral role in a Knowledge Exchange and Embed Partnerships (KEEP+) project. It provides you with the opportunity to work with a company to deliver a strategic project and also have access to university expertise and support.To apply for this vacancy please click above. Further information can be found in the job description and person specification, which can be accessed through link below. Closing date: 2 November 2018Applicants are encouraged to apply as early as possible as applications will be reviewed and candidates interviewed on a rolling basis.Informal enquiries may be made by email to ([email protected]) or ([email protected])Administrative contact (for queries only): [email protected] Please note: We are unable to accept applications by email. All applications must be made online. CV’s in isolation or incomplete application forms will not be accepted. We are fortunate to receive a large number of applications for our vacancies. Regrettably, we are not able to provide feedback to those job applicants who are not shortlisted, as it simply would not be manageable to do so. Applicants who require a certificate of sponsorship to work in the UK are encouraged to familiarise themselves with the UKVI Tier 2 certificate of sponsorship requirements in order to ensure they meet the eligibility criteria. For further information please visit the UKVI webpage on the Gov.uk website.Embracing diversity and promoting equality

8097| University College Dublin, UCD School of Electrical and Electronic Engineering| Senior Power Systems Researcher in Distributed Energy Resources, UCD School of Electrical and Electronic Engineering (Temporary)| Applications are sought for a Senior Researcher position to work on the topics of active distribution system management, distributed energy resources and control of power electronics devices in the distribution system. The position will be based in the UCD Energy Institute and UCD School of Electrical and Electronic Engineering. For this position, we are seeking a candidate to investigate the system level implications develop approach to assess the system level benefits of different control approaches for power electronics devices in distribution system, including power electronics transformers and smart inverters for distributed energy resources. The ideal candidate would be expected to have a thorough knowledge of power systems and specifically distribution systems, including experience with the modelling of DER such as electrical energy storage, wind generation and photovoltaic systems. Experience with control of power electronics converters, and validation of such approaches using real time simulation with hardware in the loop is also required.The position is part funded through the Horizon 2020 project “RE-SERVE”. Salary: €40,000 - €55,000 per annumAppointment on the above range will be dependent upon qualifications and experience.Closing Date: 17.00hrs (Local Irish Time) on 26th October 2018.Applications must be submitted by the closing date and time specified. Any applications which are still in progress at the closing time of 17:00hrs (Local Irish Time) on the specified closing date will be cancelled automatically by the system. UCD are unable to accept late applications.UCD do not require assistance from Recruitment Agencies. Any CVs submitted by Recruitment Agencies will be returned.Prior to application, further information (including application procedure) should be obtained from the Work at UCD website: https://www.ucd.ie/workatucd/jobs/.

8130| University of Calgary, Faculty of Environmental Design and Cumming School of Medicine| 2-Year Post-Doctoral Fellowship –Geospatial Analysis of Human Radon Gas Exposure in Relation to Environmental Design Metrics| Context: Our goal is to understand the geospatially distinct environmental design contributors of radiation exposure from radon gas as a source of lung cancer, and develop solutions to protect the population. Lung cancer is the leading cause of cancer death in North America and is overwhelmingly caused by chronic inhalation of tobacco smoke and/or radioactive radon gas. Radon is the primary cause of lung cancer in never smokers, encompassing 10,000-40,000 Canadians per decade. Canada contains many radon-generating regions, and Canadians have constructed population centres across all of them, although this does not mean that all buildings contain high radon. Indeed, there are three factors needed to incur hazardous radon exposure: (i) a geologic source and pathway (upwards) for radon, (ii) environmental design metrics that actively draw up and concentrate radon and (iii) human behaviour that prolongs exposure or increases radon concentrations. The postdoctoral scholar will aim to identify modifiable behaviours and environmental design practices influencing chronic radon exposure in our changing world and define engineering and community intervention solutions applicable within the Canadian context to eliminate radon as a source of cancer in the future. The mentorship team encompasses leading expertise in radon and cancer biology (Goodarzi) merged with architecture and environmental design (Taron). Qualifications: The ideal candidate will be a scholar with a PhD (within 3 years of completing PhD; ABD will be considered) in geography, architecture, urban studies, public heath, energy efficiency or a related field, who will maintain a high degree of research productivity and extend existing capacities of the growing Evict Radon research confederation of scholars. They will demonstrate a high degree of self-direction and creativity, and will ideally be familiar with the Canadian funding landscape. This position is initially for two years, with the possibility of renewal pending successful funding applications.Application closing date: November 14th, 2018Position start date: early 2019Salary: $55 000 per year plus benefits To apply, Please send your CV, a cover letter outlining broad research interests and contributions, and a one-page research proposal pertaining to the themes above, to [email protected] and [email protected] by end of November 14th, 2019. Successful short-listed applicants will be required to provide letters of reference and may be invited for an in-person or video-conference interview.

8101| University of Southampton, Earth Surface Dynamics| Research Fellow| Location: Highfield CampusSalary: £30,395 to £37,345 per annum Full Time - Fixed Term for 3 yearsClosing Date: 31/10/2018Reference: 1062718WRApplications are invited for a Research Fellow to join our project "Unnatural dynamics of flood deposits in built environments", funded by The Leverhulme Trust, on a fixed term basis for 3 years.Population and land-use pressures on river and coastal floodplains means that flood events deposit large volumes of sediment and debris in built environments. These "unnatural" flood deposits are ubiquitous, delay emergency response, and are costly to clean up. We aim to predict how spatial characteristics of built environments control the shape, scale, movement, and distribution of flood deposits. We will measure and model flood deposits in built and non-built environments to quantify and explain their differences. This project is a formative step in transdisciplinary research into how natural phenomena interact with and impact built environments.We seek a talented, quantitative, scientist who has facility and experience with numerical modelling and writing open-source code. Candidates should have a PhD* or equivalent professional qualifications and experience in a relevant subject area. A background in physical geography is preferred, but not essential: candidates with a background in cognate disciplines (e.g., physics, fluid dynamics, coastal/fluvial engineering, computer science) are encouraged to apply.The post will involve numerical modelling and data analysis, and participation in a large-scale physical experiment at the COAST Lab, a state-of-the-art facility at the University of Plymouth. Experience applying and/or modifying numerical models and analytical scripts is therefore highly desirable, but training in the necessary modelling techniques (in XBEACH) is available during the project.The successful candidate will work closely with the two principal investigators (Dr Eli Lazarus, at Southampton, & Dr Evan Goldstein, at the University of North Carolina), and will collaborate with, and help to mentor, a PhD student also working on the project. The post is hosted in the School of Geography & Environmental Science at the University of Southampton.For informal enquiries, please contact Dr Eli Lazarus ([email protected]) and/or Dr Evan Goldstein ([email protected]).It is anticipated that interviews will take place November 2018, with the intended project start date 1 January 2019.Application Procedure:You should submit your completed online application form at www.jobs.soton.ac.uk. Please ensure you include your CV and 2 page cover letter. The application deadline will be midnight on the closing date stated above. If you need any assistance, please call Geraldine Lewis (Recruitment Team) on +44 (0) 23 8059 3462. Please quote reference 1062718WR on all correspondence.*Applications for Research Fellow positions will be considered from candidates who are nearing completion of a relevant PhD qualification. The title of Research Fellow will be applied upon successful completion of the PhD. Prior to the qualification being awarded the title of Senior Research Assistant will be given.

8138| Queen Mary University of London, School of Biological and Chemical Sciences| Postdoctoral Research Assistant| A Postdoctoral Research Assistant position is available at Queen Mary University of London (QMUL) in Dr Fabrice Caudron’s group, to work on the role of prion-like proteins in cell fate and memory. Queen Mary is one of the top research-led universities in the UK and was ranked 9th among the UK multi-faculty universities in the Research Excellence Framework (REF 2014). All postdoctoral researchers are part of the QMUL Doctoral College, which provides support with high-quality training and career development activities. This research position will focus the mechanisms of condensation and function of several prion-like proteins in response to pheromone and during yeast replicative ageing. This involves classical molecular biology and yeast genetics techniques in order to perform 3D time-lapse microscopy. In addition, you will establish the production and use of microfluidics chips to perform full lifespan imaging of yeast cell, in collaboration with other research groups. You will also start translating this research to zebrafish embryos. The ideal candidate for the position will have a PhD in cell and molecular biology, with significant experience in yeast cell biology. A track record of peer-reviewed publications is essential. Experience in the production of microfluidic chips would be an asset. The post is BBSRC funded and is a full-time position, available for a period of 3 years. The start date is 1st December 2018. The salary is £33,615 per annum and is inclusive of London allowance. Benefits include 30 days annual leave and a pension scheme. Candidates must be able to demonstrate their eligibility to work in the UK in accordance with the Immigration, Asylum and Nationality Act 2006. Where required this may include entry clearance or continued leave to remain under the Points Based Immigration Scheme.Informal enquiries are welcomed, and may be made to Dr Fabrice Caudron via e-mail at [email protected] For information about the School of Biological and Chemical Sciences, please visit http://www.sbcs.qmul.ac.uk To apply, please click on the link below.Application enquiries should be directed to [email protected] closing date for applications is 15 November 2018. Interviews will be held shortly thereafter. Valuing Diversity & Committed to Equality

8141| English-Speaking Union| Lindemann Fellowship| The English-Speaking Union offers up to three grants a year, worth $50,000 each, for postdoctoral scientists to carry out their research at a host institution in the USA. The Lindemann Trust Fellowships are awarded to graduates who have shown exceptional promise and the capacity to produce original research in the applied sciences.These Fellowships enable postdoctoral scientists to pursue research in the USA without financial difficulty, and without being obliged to take up paid employment. We also offer a £1,000 grant to each Fellow to assist with travel costs. Following a legacy left by Brigadier Charles Lindemann, the ESU has run the Fellowships since March 1972.Each fellowship lasts for one year and supports research in the fields of astronomy, biophysics, chemistry, engineering, geology, geophysics, mathematics and physics.Applications for the 2019/20 Lindemann Trust Fellowships are now open. Applications close on Monday 11th February 2019. Interviews will be held on Tuesday 9th April 2019.To be eligible to apply, candidates must meet the following criteria:* Hold British, Irish or Commonwealth citizenship AND be normally resident in the UK* Either be in the final stages of your doctoral studies at a UK university, or have completed your doctorate at a UK university within the last three academic yearsCandidates will be required to complete an online application form. A letter of endorsement from the proposed host institution must be uploaded as part of this application process (please see the below ‘Notes for Host Endorsement Letter’) and two confidential references must be sent directly to the ESU before the application closing date.Successful applicants would then be invited to interview with the Lindemann Committee and members of the ESU’s international team. Fellowships may then be taken up any time between September and April of the following academic year.

8136| The University of Texas MD Anderson Cancer Center, Epigenetics and Molecular Carcinogenesis| Postdoctoral Fellowship in Signal Transduction and Proteomics| A funded postdoctoral fellowship is available in the laboratory of Dr. Mark Bedford at The University of Texas MD Anderson Cancer Center. Research on arginine methylation and the use of protein domain microarrays to interrogate signaling pathways will be carried out in the Department of Epigenetics and Molecular Carcinogenesis in Smithville. The department (near Austin, TX) is one of MD Anderson’s largest and most successful fundamental research departments. For more information, see the laboratory website:https://www.mdanderson.org/research/departments-labs-institutes/labs/bedford-laboratory.htmlMD Anderson offers many benefits and career training opportunities for postdoctoral fellows:https://www.mdanderson.org/education-training/clinical-research-training/postdoctoral-training.htmlRequirements:Applicants should have a recent Ph.D. degree in biochemistry or a highly related field, one or more first-authored publications in highly regarded scientific journals, and proven proficiency in written and spoken English. Experience with mammalian cell culture, recombinant protein purification and Western blot analysis is an advantage.Application process:Applicants should send a cover letter, CV, statement of research interest and the contact information of three references to Dr. Mark Bedford ([email protected]) with the subject line “Postdoc Application in Signaling & Arrays”.M. D. Anderson Cancer Center is an equal opportunity employer and does not discriminate on basis of race, color, national origin, gender, sexual orientation, age, religion, disability or veteran status except where such distinction is required by law. All positions at The University of Texas M. D. Anderson Cancer Center are security sensitive and subject to examination of criminal history record information. Smoke-free and drug-free environment.

8106| Queen Mary University of London, School of Biological and Chemical Sciences| Postdoctoral Research Assistant| An ERC-funded Postdoctoral Research Assistant position is available at Queen Mary University of London (QMUL) in Dr José M (Chema) Martín-Durán’s group, to work on the epigenetic regulation of conditional and autonomous development in spiral cleaving animals (e.g. annelid worms, molluscs, and nemerteans). Queen Mary is one of the top research-led universities in the UK and was ranked 9th among the UK multi-faculty universities in the Research Excellence Framework (REF 2014). All postdoctoral researchers are part of the QMUL Doctoral College, which provides support with high-quality training and career development activities.This research position will focus on identifying the maternal factors that control early spiral cleavage and account for the differences in cell fate specification modes observed among spiralian lineages. The project will involve the use of multiple animal species, and combine proteomics and single-cell transcriptomics with classic embryological approaches. The findings from the project will untangle the molecular regulation of early spiral cleavage and provide a general understanding of the evolution of novel strategies of early development.The ideal candidate for the position will have a PhD in developmental and/or evolutionary biology, with significant experience in embryological methods (in vitro fertilisation, embryo culture, in situ hybridisation, imaging), general molecular biology techniques (PCR, gene cloning, etc) and bioinformatics (RNA-seq data analyses, fluid use of command line tools and R). A track record of peer-reviewed publications is essential. Experience in single-cell RNA-seq experimental and computational methods and/or proteomics is highly desirable. The post is funded by the European Research Council (ERC) and is a full-time position. The post is available for a period 2 years, with possibility a 1 year extension thereafter. The start date is 1st February 2019 or as soon as possible thereafter. The salary is dependent on qualifications, skills and experience and is in the range of £33,615 - £39,483 per annum, inclusive of London allowance. Benefits include 30 days annual leave and a pension scheme. Candidates must be able to demonstrate their eligibility to work in the UK in accordance with the Immigration, Asylum and Nationality Act 2006. Where required this may include entry clearance or continued leave to remain under the Points Based Immigration Scheme.Informal enquiries are welcomed and encouraged, and may be made to Dr Martín-Durán via e-mail at [email protected] For information about the School of Biological and Chemical Sciences and the Martín-Durán lab, please visit martinduranlab.com and http://www.sbcs.qmul.ac.uk To apply, please click on the link below.Application enquiries should be directed to [email protected] closing date for applications is 31 October 2018. Interviews will be held shortly thereafter. Valuing Diversity & Committed to Equality

8116| University of Southampton, Ecology and Evolution| Research Fellow in Evolutionary Genomics| Location: Highfield CampusSalary: £30,395 to £31,302 Full Time Fixed Term (3 years)Closing Date: Friday 02 November 2018Reference: 1064218BJWe seek a Research Fellow to investigate “The contribution of plasticity to adaptive divergence: domestication as a model”. The NERC/BBSRC co-funded project provides support for 3 years from 7th January 2019 to work with Dr Mark Chapman in the Ecology and Evolution group at the University of Southampton (https://www.southampton.ac.uk/biosci/about/staff/mc1c12.page), co-supervised by Dr Tom Ezard in Ocean and Earth Science (https://www.southampton.ac.uk/oes/about/staff/te1e12.page).The goal of this project is to study the evolution of plasticity, comparing crops to their wild relatives, as a model for understanding the genetic basis and role of plasticity in adaptive divergence and the early emergence of new taxa.You will have a PhD* or equivalent professional qualification in a relevant subject area, with a strong evolutionary and genomic/transcriptomic component. A high level of competence in bioinformatics is required, with relevant experience demonstrated by publications in peer reviewed journals where possible. Competency in statistics and programming would be advantageous and experience with plants desirable. You should be a highly motivated scientist, capable of contributing to developing your own research project, a good team worker and an excellent communicator.Chapman and Ezard are interested in fusing evolutionary theory with experimental approaches, and you would be expected to contribute intellectually to the development of the project. A broad interest in evolution as a whole is required. The current work will use extensive greenhouse and laboratory experiments coupled with transcriptome, whole genome and methylome analyses to decipher the contribution of plasticity to adaptive divergence. It offers excellent potential for publishing in high impact journals and developing independent research agendas.You will assume leadership on the project, including significant intellectual contribution, setting up experiments and involvement in making decisions about current and future research directions. You will work in a highly collaborative atmosphere supported by state-of-the-art research facilities that will provide a perfect environment to carry out the project.For informal enquiries, please email Dr Mark Chapman ([email protected]) in the first instance. *Applications will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification. The title of Research Fellow will be applied upon successful completion of the PhD. Prior to the qualification being awarded the title of Senior Research Assistant will be given.Equal Opportunities and Benefits: Biological Sciences holds an Athena SWAN Silver Award, demonstrating commitment to equal opportunities and gender balance in the workplace. We aim to be an equal opportunities employer and welcome applications from all sections of the community. Please note that applications from agencies will not be accepted.The University of Southampton has a generous maternity policy and onsite childcare facilities; employees are able to participate in the childcare vouchers scheme. Other benefits include state-of-the-art on-campus sports, arts and culture facilities, a full programme of events and a range of staff discounts.Please include a covering letter, full CV and names and contact details for three referees in your application.Application Procedure:You should submit your completed online application form at http://www.jobs.soton.ac.uk/www.jobs.soton.ac.uk. The application deadline will be midnight on the closing date stated above. If you need any assistance, please call Sam Stubbs (Recruitment Team) on +44 (0)23 8059 4046. Please quote reference 1064218BJ on all correspondence.

8128| University College Dublin, UCD School of Chemistry| UCD Post-doctoral Research Fellow Level 1, UCD School of Chemistry (Temporary)| Applications are invited for a Post Doctoral Research Fellow Level 1 in the UCD School of Chemistry.This project will involve developing synthetic methods for production (at scale) of magnetic nanoparticles (MNPs) with strong magnetic response, forming nanocomposites by combining the MNPs with hydrogels, and evaluating their potential for tissue engineering applications. The Group have developed some of the relevant nanoparticle surface chemistry and colloidal techniques, and have expertise in hydrogel formation.In this part of the project further improvements in MNP preparation (reproducibility and scale up) will be undertaken. Novel hydrogels incorporating MNPs for controlled stimulus-response will be prepared. The response (including drug release) of bulk- and nano-gels on application of magnetic fields will be assessed.See Job Description for more details.Salary: €36,854 - €39,138 per annum.Appointment on the above range will be dependent on qualifications and experience.Closing Date: 17.00hrs (Local Irish Time) on 1st November 2018.Applications must be submitted by the closing date and time specified. Any applications which are still in progress at the closing time of 17:00hrs (Local Irish Time) on the specified closing date will be cancelled automatically by the system. UCD are unable to accept late applications.UCD do not require assistance from Recruitment Agencies. Any CVs submitted by Recruitment Agencies will be returned.Prior to application, further information (including application procedure) should be obtained from the Work at UCD website: https://www.ucd.ie/workatucd/jobs/.

8112| University of Iceland, Dep of Food Science| Biotechnology Post Doc Opportunities in Iceland| We are looking for two Post-Doctoral Fellows to work on a) research on extraction, identification and delivery of bioactives from sea weeds and other natural resources to be used in new skin care products and b) research on extraction and benefits of omega oils from geothermally grown micro-algae. The projects will be directed by Prof. Kristberg Kristbergsson at the Department of Food Science and nutrition at the University of Iceland and Director of Research and Development at TARAMAR Inc., a new company focusing on very pure skincare products and Prof. Gudrun Marteinsdottir at The School of Engineering and Natural Sciences and CEO of TARAMAR Inc. The successful candidate will be required to interact and work closely with the other researchers working on this project. Both positions are cooperative projects between the University of Iceland and TARAMAR Ltd and therefore a bridge between industry and academia offering opportunities in both.Essential experience: Applicants should have a PhD in Food Science or Food Engineering with a strong background in chemistry. A portfolio of international peer reviewed publications in relevant subject area. It is also essential that applicants have experience in project management, dissemination of research work at international conferences and technical report writing.Desirable experience: Post-doctoral experience and management of other researchers including masters and PhD students.Experience in product development is highly desirable. The first position is available for three years and is ideal for researchers who are motivated and willing to engage in project management and direction. The second position is a one year contract, with a possible extension to two years.

8090| University of Calgary, Faculty of Kinesiology| Nutrition, Obesity and Gut Microbiota| University of CalgaryFunded Postdoctoral Position Available in the area of “Nutrition, Obesity and Gut Microbiota”A funded postdoctoral fellowship in the areas of nutrition, obesity and gut microbiota is available for an early 2019 start date at the University of Calgary located in Calgary, Alberta, Canada. Dr. Raylene Reimer has been awarded funding through the University of Calgary Eyes High Postdoctoral Recruitment Strategy for a postdoctoral fellow ideally starting in early 2019. The proposed research would allow a talented postdoctoral fellow to conduct basic research testing the effect of novel dietary fibres on obesity risk associated with early life antibiotic exposure. Obesity is a major public health problem. A growing body of evidence links the gut microbiota to regulation of body weight. The gut microbiota is particularly vulnerable to perturbation during critical periods in early life. The postdoctoral fellow will be responsible for studies in rodents that examine the impact of early life antibiotic exposure on the developing gut microbiota and the impact on obesity risk. The Reimer lab has internationally recognized expertise in the use of prebiotics to modulate gut microbiota and some background in nutrition is therefore an asset. Essential to the position is training in bioinformatics directly linked to gut microbiota. Applicants with strong gut microbiota bioinformatics skills not directly related to obesity or nutrition are encouraged to apply if they have strong potential to transfer their skills to these areas of application. Interested applicants should email a copy of their graduate degree transcripts and CV to: [email protected]: http://contacts.ucalgary.ca/info/kn/profiles/196-1956

8095| Institute of Cancer Research| Post-Doctoral Training Fellow Biologist – Regulation of protein synthesis initiation| The Institute of Cancer Research, London, is one of the world’s most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. We provided the first convincing evidence that DNA damage is the basic cause of cancer, laying the foundation for the now universally accepted idea that cancer is a genetic disease. Today, The Institute of Cancer Research (ICR) leads the world at isolating cancer-related genes and discovering new targeted drugs for personalised cancer treatment.Under the leadership of our Chief Executive, Professor Paul Workman FRS, the ICR is ranked as the UK’s leading academic research centre. Together with our partner The Royal Marsden, we are rated in the top four cancer centres globally.The ICR is committed to attracting, developing and retaining the best minds in the world to join us in our mission – to make the discoveries that defeat cancer.Vacancy Description Astex PharmaceuticalsAstex Pharmaceuticals is a world leader in innovative drug discovery and development. The company has successfully applied its proprietary Fragment-Based Drug Discovery (FBDD) platform to generate multiple new drug candidates that are progressing in clinical development and is recognised as having world leading expertise in structural biology and FBDD. Astex’s Sustaining Innovation Post-Doctoral Research Program aims to maintain and further enhance the company’s excellent scientific culture by fostering basic research in areas of interest to drug discovery. The program also seeks to promote interactions between scientists from the biotech sector and academic experts in areas of common research interest.The Cancer Research UK Cancer Therapeutics Unit, within the Division of Cancer Therapeutics, is a multidisciplinary 'bench to bedside' centre, comprising around 160 staff dedicated to the discovery and development of novel therapeutics for the treatment of cancer. The Cancer Therapeutics Unit’s exciting goal is to discover high quality drug candidates for validated biological targets and to progress these candidates to clinical trial. All the scientific disciplines are in place to make this possible. Our biologists work alongside world-class chemists and drug metabolism specialists focusing on new molecular targets emerging from human genome and ground breaking cell biology research. This is an exciting and fast moving area of cancer research, and offers the opportunity to work within a multi-disciplinary environment using state-of-the-art techniques and equipment. We are seeking a highly motivated Biologist to work in our Signal Transduction and Molecular Pharmacology Team with Dr Paul Clarke, located in well-equipped laboratories in Sutton, South London. The successful applicant will use molecular, biochemical and cellular techniques to explore the regulation of protein synthesis initiation in cancer cells and to validate potential molecular targets for cancer therapy identified by the team. The project is in collaboration with Astex Pharmaceuticals and it is expected that the successful applicant will also have access to Astex’s Sustaining Innovation Post-Doctoral Research Program. Candidates should possess a PhD in Biochemistry, Molecular Biology or Cell Biology, have developed a range of skills through experience in these areas and be able to work in an interdisciplinary environment towards the goal of performing cellular and biochemical assays required for pathway analysis. Knowledge of cancer research and familiarity with contemporary approaches to drug discovery, molecular target validation is desirable. Appointment will be to a Postdoctoral Training Fellowship with starting salary in the range of £30,715 to £39,082 p.a. inclusive based on relevance of skills and experience. Appointment will be for 2 years in the first instance, and benefits from a contributory defined benefit pension scheme and generous leave entitlement. Further information can be found in the full job description at https://icr.tal.net/vx/appcentre-ext/brand-0/candidate/so/pm/1/pl/1/opp/537-Post-Doctoral-Training-Fellow-Biologist-Regulation-of-protein-synthesis-initiation/en-GBWe consider all applications on merit and have a strong commitment to enhancing the diversity of our staff.

8140| University College Dublin, UCD School of Electrical and Electronic Engineering| UCD Post- Doctoral Research Fellow Level 1, UCD School of Electrical and Electronic Engineering (Temporary)| New 5G wireless technologies aim for substantially broader coverage, with a special focus on supporting low-power Internet-of-Things (IoT) devices. One key technique underpinning the latest development of 5G-and-beyond standards is the use of multi-hop wireless connections. This project will design advanced strategies for wireless multi-hop communications, which substantially improve the delay-throughput performance of multi-hop links while significantly lowering the complexity.Two postdoctoral researchers are sought for this project: one with specific expertise in channel coding and information theory, and one with specific expertise in signal processing for wireless communications. Research challenges for the proposed new multi-hop framework include the design of new channel coding techniques and signal processing algorithms, incorporation of wireless channel estimation, performance analysis over fading channels, and testbed implementation.Salary: €37,222 - €43,029 per annum.Appointment on the above range will be dependent on qualifications and experience.Closing Date: 17.00hrs (Local Irish Time) on 12th November 2018.Applications must be submitted by the closing date and time specified. Any applications which are still in progress at the closing time of 17:00hrs (Local Irish Time) on the specified closing date will be cancelled automatically by the system. UCD are unable to accept late applications.UCD do not require assistance from Recruitment Agencies. Any CVs submitted by Recruitment Agencies will be returned.Prior to application, further information (including application procedure) should be obtained from the Work at UCD website: https://www.ucd.ie/workatucd/jobs/.

8093| MRC Laboratory of Molecular Biology, Neurobiology| Postdoctoral Scientist| Starting Salary £30,464 - £33,305 per annum Fixed Term 3 Years MRC Laboratory of Molecular Biology, Cambridge, UKThe MRC Laboratory of Molecular Biology is a world leader in biological research, with an expanding scientific programme dedicated to understanding gene function in health and disease. It provides an unsurpassed environment for both young and established researchers. Scientists are drawn to the LMB from all over the world, creating a lively and international community for the exchange of ideas and technical innovation.We are looking to recruit a molecular biologist with expertise in mouse work, and in particular, experience in conducting behavioral studies, preferably with expertise in mouse models of neurodegenerative diseases and diabetes. You will join Dr Anne Bertolotti’s pioneering research programme, which focuses on innovative approaches to rescue cells from protein misfolding, a condition at the origin of many human diseases, including neurodegenerative diseases. One of such approaches consists in selective inhibition of phosphatases, an important discovery because phosphatases were thought to be undruggable before this work (see Tsaytler et al., 2011, Science, 332, 91-4; and Das et al., 2015, Science, 348, 239-242, Carrara, M., Sigurdardottir, A., & Bertolotti, A. (2017). Nat Struct Mol Biol, 24(9), 708–716). Krzyzosiak, A., Sigurdardottir, A. et al., A. (2018). Cell, 174(5), 1216–1228.e19.)You will join a strong inter-disciplinary team at the LMB which has broad expertise extending from biochemistry, structural, chemical, molecular and cell biology through to transgenic animals models of degenerative diseases. We also have an excellent record of innovative basic research leading to applications in medicine, a passion for science and a commitment to explore the unknown.Further information about the position may be obtained from Dr Anne Bertolotti– email: [email protected] You will be ambitious, creative and fearless. You will have a PhD molecular or cell biology due to complete doctoral studies within 6 months of applying. Relevant experience is required and this must be best attested by at least one impactful publication. Experience with mouse models is essential. An interest in signaling, stress responses and protein quality control is desirable. You will be awarded a three-year MRC Career Development Fellowship/MRC Postdoctoral Training Scheme, which is a training and development position for a postdoctoral scientist who has recently completed doctoral studies or is moving into a new research discipline.The MRC Laboratory of Molecular Biology is a research institute within UK Research and Innovation (UKRI). UKRI is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at www.ukri.org.Working for UKRI MRC provides a whole host of benefits including a defined benefit pension scheme, excellent holiday entitlement (40 ½ days including bank holidays and privilege days) and Benenden Healthcare membership. You will also have access to employee shopping/travel discounts, on site sport and social facilities, as well as salary sacrifice cycle to work schemes and childcare vouchers.To apply and access full details of the vacancy please visit our job board at https://mrc.tal.net/vx/lang-en-GB/appcentre-1/candidate/postings/1049. If you are unable to apply online please contact us at [email protected] date: 28 October 2018Final appointments will be subject to a pre-employment screening.The Medical Research Council is an Equal Opportunities Employer who participates in the Disability Confident scheme.

8123| Dublin City University, School of Chemical Sciences| Postdoctoral Researcher in Liposomes and Proteoliposomes| We are seeking a postdoctoral scientist with a PhD in chemistry, biochemistry, molecular biology or related field and experience in preparation and study of liposomes, proteoliposomes or supported lipid bilayers. The researcher will contribute to projects focussed on assaying integrin aggregation and membrane transporter function in model cell membranes. Experience in preparation and handling of liposomes or proteoliposomes is essential. In particular, candidates with experience of working with giant unilammelar vesicles (GUVs) and their electroformation are particularly sought. Experience in biophysical analysis of biomembranes is an advantage and candidates with experience in confocal fluorescence microscopy and fluorescence correlation spectroscopy and/or in electrochemical impedance spectroscopy are particularly encouraged to apply. The candidate should have a PhD in chemistry, physical chemistry or related discipline with significant experience in preparation of plasmonic metal substrates for SERS and in computation analysis (numerical simulation) of plasmonic fields of SERS substrates. The candidate should have experience in Raman spectroscopy/microscopy and experience in fluorescence microscopy/lifetime imaging would also be an advantage.

8126| ICR| Post Doctoral Training Fellow - Biologist| Closing Date: 06/11/2018 Location: Sutton Division: Cancer TherapeuticsTeam: Translational Cancer DiscoveryVacancy Type: Full timeType of Contract: Fixed TermLength of Contract: 2 yearsHours per Week: 35Salary Range: £35,109 - £40,409The Institute of Cancer Research, London, is one of the world’s most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. We provided the first convincing evidence that DNA damage is the basic cause of cancer, laying the foundation for the now universally accepted idea that cancer is a genetic disease. Today, The Institute of Cancer Research (ICR) leads the world at isolating cancer-related genes and discovering new targeted drugs for personalised cancer treatment.Under the leadership of our Chief Executive, Professor Paul Workman FRS, the ICR is ranked as the UK’s leading academic research centre. Together with our partner The Royal Marsden, we are rated in the top four cancer centres globally.The ICR is committed to attracting, developing and retaining the best minds in the world to join us in our mission – to make the discoveries that defeat cancer.The Cancer Research UK Cancer Therapeutics Unit, within the Division of Cancer Therapeutics, is a multidisciplinary 'bench to bedside' centre, comprising around 160 staff dedicated to the discovery and development of novel therapeutics for the treatment of cancer. The Cancer Therapeutics Unit’s exciting goal is to discover high quality drug candidates for validated biological targets and to progress these candidates to clinical trial. All the scientific disciplines are in place to make this possible. Our biologists work alongside world-class chemists and drug metabolism specialists focusing on new molecular targets emerging from human genome and ground breaking cell biology research. This is an exciting and fast moving area of cancer research, and offers the opportunity to work within a multi-disciplinary environment using state-of-the-art techniques and equipment.This Unit is now under the leadership of Professor Rajesh Chopra who has previously held senior leadership positions at AstraZeneca and Celgene and academic positions in the UK in haematological oncology and stem cell transplantation.We are seeking a highly motivated Biologist to work in our new Translational Cancer Discovery Team (led by Professor Rajesh Chopra), located in well-equipped laboratories in Sutton, South London. This is a newly created post that has arisen as a result of collaboration between the Cancer Therapeutics Unit at the ICR and a new company (founded by Professor Ian Collins and Professor Raj Chopra) established to target protein degradation. This exciting initiative is an important part of our future drug discovery strategy and is part of an exciting industrial collaboration to develop novel modulators of E3 ligases for treatment of cancers.The successful applicant will use molecular, biochemical and cellular techniques to validate the molecular target and identify biomarkers of compounds that target a variety of difficult to drug targets such as c-MYC and RAS signalling.In addition we are developing novel organotypic assays for cancer cells in order to undertake cancer drug screening in a physiologically relevant manner. Finally the team will develop novel approaches to modulate antigen presentation.Candidates should possess a PhD in Biochemistry, Molecular Biology or Cell Biology, have developed a range of skills through experience in these areas and be able to work in an interdisciplinary environment towards the goal of performing cellular and biochemical assays required for pathway analysis. Knowledge of cancer research and for immunology and familiarity with contemporary approaches to drug discovery, molecular target validation is desirable. Starting salary in the region of £35,109 to £40,409 pa inclusive (based on previous experience). Appointment will be for 24 months in the first instance. Further information can be found in the full job description below. Previous applicants for this post need not apply.

8098| University College Dublin, UCD School of Electrical and Electronic Engineering| Senior Power Systems Researcher in Distributed Energy Resources, UCD School of Electrical and Electronic Engineering (Temporary)| Applications are sought for a Senior Researcher position to work on the topics of active distribution system management, distributed energy resources (DER) and control of power electronics devices in the distribution system. The position will be based in the UCD Energy Institute and UCD School of Electrical and Electronic Engineering.For this position, we are seeking a candidate to work on the development of methods to assess the system level benefits of different control approaches for power electronics devices in the distribution system, including power electronics transformers and smart inverters for distributed energy resources. The ideal candidate would be expected to have a thorough knowledge of power systems and specifically distribution systems, including experience with the modelling of DER such as electrical energy storage, wind generation and photovoltaic systems.Responsibilities will include working with other members of the team and with our project partners to deliver on the overarching scientific goals of the project.See Job Description for more details.Salary: €43,394 - €47,255 per annum.Closing Date: 17.00hrs (Local Irish Time) on 1 November 2018.Applications must be submitted by the closing date and time specified. Any applications which are still in progress at the closing time of 17:00hrs (Local Irish Time) on the specified closing date will be cancelled automatically by the system. UCD are unable to accept late applications.UCD do not require assistance from Recruitment Agencies. Any CVs submitted by Recruitment Agencies will be returned.Prior to application, further information (including application procedure) should be obtained from the Work at UCD website: https://www.ucd.ie/workatucd/jobs/.

8113| The Institute of Cancer Research, Division of Cancer Therapeutics| Post-Doctoral Training Fellow Biologist - Regulation of HSF1 in cancer cells| The Cancer Research UK Cancer Therapeutics Unit, within the Division of Cancer Therapeutics, is a multidisciplinary 'bench to bedside' centre, comprising around 160 staff dedicated to the discovery and development of novel therapeutics for the treatment of cancer. The Cancer Therapeutics Unit’s exciting goal is to discover high quality drug candidates for validated biological targets and to progress these candidates to clinical trial. All the scientific disciplines are in place to make this possible. Our biologists work alongside world-class chemists and drug metabolism specialists focusing on new molecular targets emerging from human genome and ground breaking cell biology research. This is an exciting and fast moving area of cancer research, and offers the opportunity to work within a multi-disciplinary environment using state-of-the-art techniques and equipment.We are seeking two highly motivated Biologists to work in our Signal Transduction and Molecular Pharmacology (STMP) Team with Dr Paul Clarke & Professor Paul Workman, located in well-equipped laboratories in Sutton, South London. The successful applicants will use molecular, biochemical and cellular techniques to explore to validate potential molecular targets that regulate the transcriptional response to heat shock and other stresses in cancer cells.Candidates should possess a PhD in Biochemistry, Molecular Biology or Cell Biology, have developed a range of skills through experience in these areas and be able to work in an interdisciplinary environment towards the goal of performing cellular and biochemical assays required for pathway analysis. Knowledge of cancer research and familiarity with contemporary approaches to drug discovery, molecular target validation is desirable.Appointment will be to a Post-Doctoral Training Fellowship with starting salary in the range of £30,715 to £39,082 p.a. inclusive (based on previous experience). Appointment will be for 3 years in the first instance, and benefits from a contributory defined benefit pension scheme and generous leave entitlement. To find more information and to apply online please follow the link to ICR Careers webpage

8125| National Oceanography Center (NOC)| Postdoctoral Research Associate| Postdoctoral Research AssociateUKRI - NERC NOCSouthampton£28,200 - £32,430Full time/Part Time (hour’s subject to negotiation)Fixed term (2 years) contract length variable for part time rolesAbout UsThe Natural and Environmental Research Council (NERC) is a partner organisation within UK Research and Innovation (UKRI). UKRI is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, and a vision to ensure the UK maintains its world-leading position in research and innovation. The National Oceanography Centre (NOC), part of NERC, is a national research organisation, delivering integrated marine science and technology from the coast to the deep ocean and is one of the top five institutions of its kind in the world.BenefitsIn return for your talents, we offer a competitive remuneration package, including a RCUK pension scheme, 30 days annual leave with a further 14 Public/local days off and free car-parking. Opportunities for further training and development are supported.About the roleWe are looking to recruit an enthusiastic and motivated scientist, with experience in physical oceanography and its role in climate, to carry out Lagrangian analyses of drifter trajectories (observed and modelled). You will diagnose freshwater pathways originating in Arctic and Greenland melt water using drifters deployed on the shelves around Greenland. You will then use the observed and modelled pathways and additional datasets, to identify processes by which freshwater crosses off the continental shelf and into the deep ocean in the subpolar North Atlantic.You will work as part of the TERIFIC team (a new EU-funded project called Targeted Experiment to Reconcile Increased Freshwater with Increased Convection), within the Ocean Circulation and Processes subgroup at the National Oceanography Centre in Southampton. Key responsibilities: • analysis of numerical simulations of drifters to plan drifter deployments and contribute to the TERIFIC scientific aims• drifter deployments and related logistics for TERIFIC fieldwork• quality control of drifter dataset• analysis of drifter dataset and related observational-based products to investigate the pathways of freshwater around Greenland and the Labrador Sea in order to contribute to the TERIFIC scientific aims• publish and present results from the TERIFIC project.About youYou will have a PhD in physical oceanography with experience in oceanographic observations and their analysis. You must have a good knowledge of ocean dynamics and its role in climate systems with strong quantitative skills, good communication and interpersonal skills and a publication record appropriate to your career stage.You should have an interest in presenting your results at national and international conferences.Participation in fieldwork expeditions (anticipated for 2019/20) is desirable but not required.How to ApplyApplicants are required to include a cover letter outlining their suitability for this role. Applications are handled by UK SBS; to apply please click the apply button. Applicants who are unable to apply online should contact us by telephone on +44 (0)1793 867000.The closing date for applications is 11th November 2018.

8107| The Roskamp Institute, Inc.| Scientist I position in biomarker and drug discovery for neurological illnesses (equivalent to post-doctoral position):| The Roskamp Institute, Inc., is a vibrant biomedical research organization in Sarasota, FL, that is focused on understanding and developing cures for neurodegenerative diseases including Alzheimer’s Disease, traumatic brain injury and Gulf War Illness. The institute offers variety of opportunities for a career in science which includes basic and applied research as well as translational research in molecular biology and systems biology. The Roskamp Institute provides a strong comprehensive compensation package. Main Activities / Responsibilities: Ideal candidate will participate in ongoing studies of molecular and cellular neurobiology in developmental or aged related brain disorders. Candidates must have a strong background in: (1) cell biology, including primary cell cultures of neurons, glia, endothelial cells and stem cells, and immunohistochemistry; (2) molecular biology, including transgenic technology, molecular cloning, vector design and construction, enzyme assays and purification; and (3) experience in performing animal studies.Examples of Job Requirements: • Planning and conducting experiments • Recording and analyzing data• Presenting results to senior/other research staff• Preparing and writing research protocols, papers, reports, reviews and summaries• Demonstrating procedures• Supervising junior staff including technicians• Ensuring that quality standards are met• Keeping up to date with relevant scientific and technical developments• Contribute to the submission of research proposals and contracts to funding agencies• Train, mentor and supervise experimental laboratory staff with techniques and experimental procedures, and lead the development of new procedures and protocols.Qualifications: • PhD degree in biological sciences is preferred.• Excellent verbal and written communication skills.• Good self-organizational and presentation skills. • Excellent inter-personal skills.• Ability to interact with individuals with varying levels of experience and background while working closely with colleagues, students and research assistants.• Ability to demonstrate technical communication skills • Background in molecular biology and inflammation• Demonstrated record of publication in peer-reviewed journals.• Willingness to learn new techniques. • Excellent organizational, time management, and multitasking skills.• Capable of working in a team environment with an interdisciplinary focus and with an emphasis on translational medicine.• Creativity, independence, and self-motivation, with good communication skills.

8111| The Medical Research Council (MRC)| Policy and Governance Manager| Policy and Governance ManagerUKRI - MRCSwindon£37,789 - £41,988Full timeOpen endedAbout UsThe Medical Research Council (MRC) is a partner organisation within UK Research and Innovation (UKRI). UKRI is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, and a vision to ensure the UK maintains its world-leading position in research and innovation. The MRC is a publicly-funded organisation dedicated to improving human health. We support research across the entire spectrum of medical sciences, in universities and hospitals, and in our own units and institutes.BenefitsChoosing to come to work at the MRC means that you will have access to a whole host of benefits from a defined benefit pension scheme and excellent holiday entitlement to access to employee shopping/travel discounts and salary sacrifice cycle to work scheme, as well as the chance to put the MRC and UKRI on your CV in the future.About the roleThe overall purpose of this role is to support the Director of Policy, Ethics and Governance and the Executive Chair in:• developing and implementing research related policy• ensuring the MRC contributes effectively to policy discussions relevant to medical and health research both within UKRI and nationally• maintaining good governance within the MRC, meeting reporting requirements within UKRI and supporting effective operation of the MRC Council and any subcommittees.Key responsibilities:• provide support on policy relating to animals in research and engage with research funders and other stakeholders, including the Animals in Science Regulation Unit• work with the communications team to support transparency about animal research• keep abreast of policy discussions and publications relating to research integrity and reproducibility, advise senior staff and contribute to development of relevant policy or initiatives, working with other stakeholders as required• manage the review and updating of policy and governance documents• engaging with staff from across MRC, other research councils and NC3Rs to support policy implementation and identify issues that need addressing• managing the secretariat for MRC’s Council and the MRC Ethics, Regulation and Public Involvement Committee, including planning agendas, producing papers, managing members’ induction and appraisal, and ensuring conflicts of interest are identified and managed appropriately• represent MRC in cross-UKRI discussions on governance, research policy and ethics.About youYou will be educated to PhD level or equivalent and will have significant experience of working in research, research policy or research management in life sciences or a health related field. You should have experience of organising senior-level meetings and writing minutes and reports as well as having previous involvement in working with external stakeholders and representing your organisation. You must have excellent communication skills and experience of dealing with people across all levels of management, including executive and senior management. You should have knowledge of university and medical research sectors and be familiar with the policy environment for science and research. How to ApplyApplicants are required to include a cover letter outlining their suitability for this role. Applications are handled by UK SBS; to apply please click the apply button. Applicants who are unable to apply online should contact us by telephone on +44 (0)1793 867000.The closing date for applications is 21st October 2018.