8021| Birkbeck University of London, Biological Sciences| Postdoctoral Researcher in Computational Biology| The Institute of Structural and Molecular Biology (ISMB) at Birkbeck College/University College London is seeking a highly-motivated and creative Post-Doctoral Researcher to carry out computational research in protein-interaction networks and mass spectrometry-based proteomics. The position is a part of a collaborative project with groups at Birkbeck, UCL, Oxford and Hamburg funded by the Wellcome Trust to analyse and characterize novel complexes associated with Human Cytomegalovirus (HCMV) assembly.The Post-Doctoral Researcher should have a strong track record in developing computational methods in network analysis, proteomics, bioinformatics or similar fields. Knowledge in protein-protein interactions, database development and raw mass spectrometry data analysis will be an advantage.The Post-Doctoral Researcher will benefit from the vibrant scientific environment of the ISMB. She/he will also participate in international scientific conferences and workshops to present the developed techniques and software.For information about the, ISMB and the departments please visit the following websites:http://www.ismb.lon.ac.uk/http://www.bbk.ac.uk/biology/Information on the research groups can be found at:http://topf-group.ismb.lon.ac.uk/ http://www.homepages.ucl.ac.uk/~ucbtkth/The salary for this role will be on Grade 7 of the College's London Pay Scale which is £37,169 rising to £42,483 per annum. The salary quoted includes a consolidated Weighting/Allowance which applies only to staff whose normal contractual place of work is in the Greater London area.If you would like to know more about the role please click on apply below or contact Professor Maya Topf ([email protected]) and Dr Konstantinos Thalassinos ([email protected]).While we are happy to respond to all informal enquiries, only formal applications through the online system will be considered.We welcome applicants from all sections of the community. The College is committed to improving the gender & cultural diversity of its workforce, holding an Athena SWAN award, membership of WISE, operating Disability Confident & Mindful Employer schemes.Closing Date for applications: Midnight on 16th September 2018Interviews will be held in late September 2018

8006| ETH Zurich, Department of Biosystems Science and Engineering| Postdoc in stem cell technology| ETH Zürich’s Department of Biosystems Science and Engineering is looking for an outstanding scientist to fill a postdoc position in the area of stem cell technology. Research will focus on the development of tools to reproducibly steer cell-fate and morphogenesis based on stem cell self-organization properties in response to cues. It is part of a 5-year EU-funded project that will capitalize on the skills of a network of laboratories to build and demonstrate a technology for controlling the development of engineered tissues.Postdoc Position - Stem cell technology (100%)The Postdoc will be part of an exciting and stimulating research environment, working closely with an international and interdisciplinary team of researchers in the group of Prof. Mustafa Khammash, which combines experimental methods with quantitative analyses for cutting-edge research in synthetic and systems biology. The postdoc will have opportunities for professional growth including opportunity to learn about mathematical modelling and systems approaches to biology. We offer a competitive salary according ETH Standards. Candidates must have a PhD degree in molecular biology or a related field with experience in mammalian synthetic biology and cell engineering. Ideal candidates will also have expertise in CRISPR/Cas9 techniques, optogenetics, mammalian stem cell biology and state-of-the-art microscopy methods.Our department (D-BSSE) is a truly interdisciplinary research unit of the ETH Zurich where theory, experimental biology and engineering groups team up to foster advances in Systems Biology, Biotechnology and Synthetic Biology. With its headquarter in Basel, Switzerland, the D-BSSE is situated in the heart of the Biovalley, a tri-national region hosting 40% of the global life science industry including several pharma giants, which provides a unique environment for high-leverage translational research.We look forward to receiving your online application including a cover letter, CV, a statement of scientific achievement, a summary of future research plans, and the name of 3 references until Sept 15, 2018. Please note that we exclusively accept applications submitted through our online application portal. Applications via email or postal services will not be considered.For further information, please visit our website www.bsse.ethz.ch.

8012| University of Oxford, MRC Weatherall Institute of Molecular Medicine| Postdoctoral Scientist in Developmental and Stem Cell Biology| This is a unique opportunity for a motivated and highly skilled Postdoctoral Scientist to join the research group of Professor Adam Mead at the MRC Weatherall Institute of Molecular Medicine (WIMM) to use a number of state-of-the-art molecular and cellular techniques to undertake a project focused on identification and therapeutic targeting of abnormal bone marrow stromal cells in myelofibrosis, a severe myeloproliferative neoplasm. The Mead laboratory is focused on studying normal and malignant haematopoiesis, with a focus on single-cell approaches. This exciting project, at the forefront of its field, will employ combined single-cell targeted mutational analysis and RNA-sequencing as well as single-cell proteomics with novel in vivo models to determine the molecular mechanism driving the destructive bone marrow fibrosis in myelofibrosis. The goal is to identify and validate novel targets that may reduce fibrosis and improve survival for patients with this disease. The position is available fixed-term until 31 October 2021, funded by the Kay Kendall Leukaemia Fund.You will hold a PhD (or near to completion) in haematopoiesis or a relevant area, with experience in molecular biology, FACS analysis and cell culture techniques. A strong publication record in peer-reviewed journals is necessary, as well as the ability to work independently and as part of a team. You will have excellent communication and organisational skills, with the ability to manage and independently drive, innovate and complete your own research and associated activities.Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application.The closing date for this position is 12 noon on Monday 10 September 2018. Committed to equality and valuing diversity

8009| National Oceanography Center| Research Engineer, In-Situ Sensors| Research Engineer, In-Situ SensorsUKRI - NERC NOCSouthampton£28,200 - £32,430 (dependant on qualifications and experience)Full timeFixed term (3 years)About UsThe Natural and Environmental Research Council (NERC) is a partner organisation within UK Research and Innovation (UKRI). UKRI is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, and a vision to ensure the UK maintains its world-leading position in research and innovation. The National Oceanography Centre (NOC) is a national research organisation, delivering integrated marine science and technology from the coast to the deep ocean and is one of the top five institutions of its kind in the world. With sites in Liverpool and Southampton, it is the UK’s leading centre for sea level science, coastal and deep ocean research and technology development. BenefitsIn return for your talents, we offer a competitive remuneration package, including a RCUK pension scheme, 30 days annual leave with a further 14 Public/local days off and free car-parking. Opportunities for further training and development are supported.About the roleWe are seeking a talented Research Engineer to drive further innovation, development and commercialisation of our current and future microfluidic sensor technologies. You will also be a consulting engineer for these technologies. You will join an existing team of forty research staff, engineering staff and graduate students equipped with world class fabrication, testing and design facilities, together with instrumentation and analytical laboratories and access to sea going and polar research logistics.You will lead the design of in situ (i.e. deep sea submersible) microfluidic sensors through innovation and by improving current prototypes for marine and other hostile environments. This will include chemical (e.g. nutrients, carbonate, trace metals) and biological (e.g. cytometer, nucleic acid analyser, immunosensor) sensors. This sensor technology is deployed at sea, in coastal areas and in Polar Regions. These sensors provide data for use in environmental and climate modelling, in industrial applications such as Carbon Capture and Storage and for improving our understanding of the world’s oceans. Key responsibilities: • be a lead Engineer and technical consultant for autonomous in situ sensor systems and instruments for a range of projects and applications• lead production of peer reviewed publications, patents and knowledge exchange activities and contribute to grant applications• contribute to the development and maintenance of project plans• work as part of a team by providing training, engineering, fieldwork and administrative support• supervision of students within the team where appropriate.About youYou must have proven ability in solving research, engineering, manufacturing and organisational problems. A PhD in Instrumentation Engineering R&D/design or closely related discipline or equivalent research experience in an academic or industrial setting is essential. Experience of microfluidic systems, optics and biological or chemical sensors would be advantageous. You will have a broad spectrum of skills and have a flexible approach, demonstrating your ability to deliver solutions to complex problems and to quickly master new techniques. How to ApplyApplicants are required to include a cover letter outlining their suitability for this role. Applications are handled by UK SBS; to apply please click the apply button. Applicants who are unable to apply online should contact us by telephone on +44 (0)1793 867000.The closing date for applications is 16th September 2018.

7998| UKRI Medical Research Council, Laboratory of Molecular Biology| Postdoctoral Scientist - Neurobiology - Dr Rebecca Taylor - LMB 894| Postdoctoral Scientist – Neurobiology Starting Salary £30,464 - £33,305 per annum 3 Years Fixed Term MRC Laboratory of Molecular Biology, Cambridge, UKThe MRC Laboratory of Molecular Biology is a world leader in biological research, with an expanding scientific programme dedicated to understanding gene function in health and disease. It provides an unsurpassed environment for both young and established researchers. Scientists are drawn to the LMB from all over the world, creating a lively and international community for the exchange of ideas and technical innovation.We are looking for a postdoctoral scientist to join Dr Rebecca Taylor’s pioneering research programme, which focuses on defining the mechanisms utilized by neurons to activate cell non-autonomous stress responses.Candidates should have a PhD in a relevant field of biology, or be due to complete doctoral studies within 6 months of applying, and should have experience in molecular biology, biochemistry, and genetic techniques. A background in proteostasis or neurodegeneration, and some experience with C. elegans would be an advantage. Applicants should also be creative, enthusiastic, self-motivated and enjoy interacting with a dynamic interdisciplinary team sharing a passion for science and a commitment to explore the unknown. The successful candidate will be awarded a three-year MRC Career Development Fellowship/MRC Postdoctoral Training Scheme, which is a training and development position for a postdoctoral scientist who has recently completed doctoral studies or is moving into a new research discipline.Further information about the position may be obtained from Dr Rebecca Taylor – email: [email protected] The MRC Laboratory of Molecular Biology is a research institute within UK Research and Innovation (UKRI). UKRI is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at www.ukri.org.Working for UKRI MRC provides a whole host of benefits including a defined benefit pension scheme, excellent holiday entitlement (40 ½ days including bank holidays and privilege days) and Benenden Healthcare membership. You will also have access to employee shopping/travel discounts, on site sport and social facilities, as well as salary sacrifice cycle to work schemes and childcare vouchers.Closing date: 9th September 2018 Final appointments will be subject to a pre-employment screening.The Medical Research Council is an Equal Opportunities Employer who participates in the Disability Confident scheme.

7995| University of Roehampton, Life Sciences| Daphne Jackson Fellowship Opportunity at the University of Roehampton| Daphne Jackson Fellowship Opportunity at the University of RoehamptonApplications are invited for a three year Daphne Jackson Fellowship that will be hosted by the University of Roehampton. The fellowship is intended for individuals returning to research in the broad disciplines of Zoology and Ecology, and they will join the Centre for Research in Ecology, Evolution and Behaviour (CREEB) within the Department of Life Sciences.At the time of application, applicants must be based in the UK with the right to work without a visa.The University is committed to the principles of Athena SWAN and the promotion of equality and diversity.The University of Roehampton will host and half-sponsor this three-year fellowship. The remaining funding will be secured by the Daphne Jackson Trust from an additional sponsor.Daphne Jackson FellowshipsThe Daphne Jackson Trust is dedicated to returning scientists, engineers, technologists and mathematicians to their careers following a break taken for family, caring or health reasons. Daphne Jackson Fellowships are unique - they offer STEM professionals wishing to return to a research career after a break of two or more years, the opportunity to balance an individually tailored retraining programme with a challenging research project in a suitably supportive environment. The Fellowships consist of a challenging research project and at least 100 hours retraining per year. The unparalleled support offered by the Trust's Fellowship Advisors and administrative staff, coupled with mentoring and retraining provided during the Fellowship, give returners the confidence and skills they need to successfully return to research.For further details about the Trust and our fellowship scheme, please visit www.daphnejackson.org. For further information before submitting an application please contact the Trust office on 01483 689166 or via email at [email protected] further information specifically about this sponsored fellowship opportunity at the University of Roehampton, please contact Dr Lewis Halsey in the Department of Life Sciences (tel: 020 8392 8120; email: [email protected]).To be considered for this opportunity, please complete the CV and personal details information forms that can be found on the Daphne Jackson Trust website: Submitting your personal statement and CV Please email your submission to the Daphne Jackson Trust office at [email protected] stating clearly that you are interested in the University of Roehampton Sponsored Fellowship opportunity.The closing date for applications is Sunday 4th November 2018.

8014| EPFL, ENAC IIE TOPO| Post-Doctoral Researcher in Aerial Robotics for Mapping| EPFL-TOPO (Geodetic Engineering Laboratory) is committed to foster the foundation and development of tools and novel concepts for navigation and sensor fusion into the operational environment of light-weight drones of different shapes to enhance substantially their real-time estimate of trajectory as well as navigation integrity in areas with sporadic or no satellite positioning. We also aim at integrating a novel paradigm of mutli-sensor fusion in high-resolution mapping, solving the current limitations of orientating scanners and/or line sensors over surfaces lacking heterogeneous texture. More information about the lab can be found on the lab webpage https://topo.epfl.ch/We are currently looking for a post-doctoral researcher to join our group as soon as possible.Main duties and responsibilities include • Contribution to the research effort of the group involving regular interaction with PhD and MSc students, as well as external partners (from industry). • Partial responsibility in realization of current research projects and acquisition of new ones. • Some participation in teaching is also expected.Your profile• PhD degree in Robotics, Computer Science, Geomatics, Aeronautics, Electrical Engineering or a similar area.• Very good knowledge of written and spoken English.• Working knowledge of French or a strong desire to acquire it quickly.• Mathematic background in sensor fusion and estimation methods.• Hands-on experience in robotics and navigation techniques.• Good knowledge in languages and tools as C, C++, Matlab, ROS.We offer• A fascinating research topic in sensor fusions for new generation of lightweight and autonomous mapping platforms, funding of which is already secured for several years.• Access to state-of-the-art navigation, mapping sensors and in-house developed mapping platforms. • Special infrastructure for simulation and sensor calibration. • A modern working environment in a young, dynamic and international team.• Experience in industry oriented projects.Start date to be agreed upon, but earlier is betterWork rate 100%.

8017| University of Freiburg| 3 year Postdoctoral position in Plant Embryo Development| We are seeking highly motivated candidates to investigate how an embryo is formed from a single-celled zygote. A specific focus will be on the integration of parental signals into embryo patterning and the epigenetic regulation of embryo development. Unlike in most animals, the zygote of plants is transcriptionally active and in response to the fertilization event and to signal from the parents activates embryo axis formation and patterning. We previously showed that the Arabidopsis zygote transcribes regulator genes for the apical (shoot) and the basal (root) lineage, the homeodomain transcription factors WOX2 and WOX8/9, respectively (Breuninger et al. 2008). WOX8/9 expression is initiated in the zygote through a MAP kinase signaling cascade activated by the sperm and by homeodomain proteins derived from the egg cell (Ueda et al 2011, Ueda et al.2017). Only after the division of the zygote, WOX2 expression becomes restricted to the apical cell and WOX8/9 to the basal cell (Haecker et al. 2004). WOX2 subsequently regulates the initiation of the shoot meristem stem cells and WOX8/9 of root meristem stem cells (Zhang et al. 2017, and unpublished). The function of both pathways is tighly connected to balancing phytohormone action in the embryo (Roberts et al. 2018; Zhang et al. 2017).The goal of this DFG funded project is to elucidate the epigenetic network that regulates early embryo development. The candiate is expected to combine synthetic biology with molecular genetics of cell signaling and transcriptional regulation. Furthermore, the candidate is encouraged to participate in our international collaborations to integrate research results into agrucultural application, such as regeneration of crop plants via somatic embryos. The postdoctoral position is initially available for three years, with the possibility of extension and for developing an independent research profile. The lab language is English. German is not required. For further information on the Laux lab, please visit our homepage (www.biologie.uni-freiburg.de/LauxLab). The University of Freiburg with a strong and international scientific community is routinely among the best German Universities in international rankings, and advanced facilities for synthetic biology, high throughput analysis, and live imaging are available. The city of Freiburg is located in the Black Forest, next to France, Switzerland, and the Alps.To apply, please send your CV including your research experiences and your future interests to Thomas Laux ([email protected]).The Position will be open until a suitable candidate has been foundBreuninger et al. (2008). Differential expression of WOX genes mediates apical-basal axis formation in the Arabidopsis embryo. Developmental Cell 14, 867-876.Robert et al. (2018). Maternal auxin supply contributes to early embryo patterning in Arabidopsis. Nature Plants doi: 10.1038/s41477-018-0204.Ueda, et al. (2017). Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote. Genes Development, 31, 617-627.Ueda et al. (2011). Transcriptional activation of Arabidopsis axis patterning genes WOX8/9 links zygote polarity to embryo development. Developmental Cell 20, 264-270.Zhang et al. (2017). A molecular framework for the embryonic initiation of shoot meristem stem cells. Developmental Cell, 40, 264–277.

7989| University of Liverpool, Faculty of Science and Engineering| Postdoctoral Research Associate Grade 7| Faculty of Science and EngineeringSchool of EngineeringDepartment of Mechanical, Materials and Aerospace EngineeringPostdoctoral Research Associate Grade 7£33,518 - £38,833 paWe are seeking to recruit a Postdoctoral Research Associate to work on the topic of numerical analysis of transonic aircraft aerodynamics, specifically the investigation of shock-buffet flow instability. You will be involved in developing modal (global/resolvent) analysis tools using high-fidelity computational fluid dynamics, in validating and applying the developed tools using high-performance computing systems, and in scrutinising the flow physics on infinite wings and practical aircraft models. Since the project is in collaboration with the University of Southampton, who will be running highest-fidelity simulations, you must be a team player and willing to travel occasionally. You should have a PhD (or be about to obtain) in computational fluid dynamics/aerodynamics with a strong focus on and interest in aircraft applications, numerical analysis and stability theory, and high-performance scientific computing. The post is available until 30 Sept 2021.Job Ref: 009749/FINDAP Closing Date: 30 August 2018For full details and to apply online, please visit: https://recruit.liverpool.ac.uk

7983| EPFL, ENAC IIC GR-GN| Postdoc position in the field of Process design, simulation and Laboratory experiments of Biorefinery Concepts| The Bioenergy and Energy Planning Research Group at the Institute of Civil Engineering is undertaking research work in sustainability of biorefineries that include compositional analyses of biomass and conversion into biofuels and other bio-products as well as sustainability assessment. More information about the group can be found on the group webpage https://bpe.epfl.ch/To strengthen the group, we look for postdocs who have a strong background in these areas.• Process design and simulation using ASPEN PLUS of prospective biorefineries included second generation bioethanol and biodiesel and other bio-products• Experiments at bench scale for comparison of various biochemical biorefinery concepts• Contribution to sustainability impact assessment of biorefinery schemes (economic, social, environmental and multiple criteria analyses)• Contribution to students’ supervisionThe research aims to design, document and assess various concepts and configurations of biorefinery, including biofuels and other bio-products.The applicants responsibility will be  To conduct lab experiments in conversion of lignocellulosic feedstock into bioethanol and other bio-products To contribute to sustainability impact assessment using tools such as ASPEN PLUS, SIMAPRO and Multiple Criteria Analyses To contribute to student’s supervisionApplicants will preferably hold a PhD in chemistry or biotechnology and be interested in multidisciplinary research works on biofuels and biorefineries. Experience with the software ASPEN PLUS and SIMAPRO as well as computational thinking and practices will be valuable. Although EPFL is located in the French-speaking part of Switzerland, much written works at EPFL are to be prepared in English. Competence in both written and oral English is required.The EPFL offers state-of-the-art computational and experimental facilities, an inspiring and international working environment as well as internationally competitive salaries.For more information about this position and additional information on the projects, please contact Prof. Edgard Gnansounou [email protected] applicants should include a cover letter, curriculum vitae, transcript of degree, a one-page summary of research accomplishments and interests, and 3 letters of recommendation.

8010| Klinikum der Universität München| Postdoc Position| The Institute for Cardiovascular Prevention offers a to study the role of chemokine receptors CCR8 in chronic inflammation. Using atherosclerosis as a disease model for chronic inflammation, the project will interrogate the cell-specific (lymphocytes and dendritic cells) and systemic effects of the receptor in inflammatory responses in atherogenesis and atheroprogression in mouse models and human samples. The postdoc position is part of the SFB 1123 (www.sfb1123.med.uni-muenchen.de/index.html) and therefore offers excellent scientific collaborations.We seek:Eligible candidates should have experience with mouse models, immunological and molecularbiological techniques, a strong motivation and team spirit. Solid English skills written and spoken are mandatory. The successful candidate should hold an above-average PhD degree in biological sciences or related fields and have experience with basic methods of molecular and cellular biology. The postdoc will work at the institute for cardiovascular prevention (IPEK) at the LMU in Munich, Germany (www.klinikum.uni-muenchen.de/Institut-fuer-Prophylaxe-und-Epidemiologieder-Kreislaufkrankheiten/de/0600-Institute/index.html).We offer:The applicant will work in a group of experienced staff, PhD students, postdocs and technicianswith excellent infrastructure. Salary will be according to TV-L. The position is funded for three to four years.Presentation costs can unfortunately not be refunded. Applications from severely handicapped persons with basically similar qualification will be given priority.Please note that in case of transmitting your job application by email your data will not beencrypted and might potentially be noticed or adulterated by unauthorized third parties.Interested candidates should submit their electronic application till 15th September, 2018 (CV, publication list and references – max. ten pages all together as a combined PDF) to:Klinikum der Universität MünchenInstitut für Prophylaxe und Epidemiologie der KreislaufkrankheitenMs. Dr. rer. nat. Yvonne DöringPettenkoferstraße 980336 Munich, GermanyMs. Yvonne Döring, email: [email protected] Christian Weber, email: [email protected] van der Vorst, email: [email protected]

8019| Medical Research Council, London Institute of medical Sciences| MRC Postdoctoral Research Scientist| MRC Postdoctoral Research Scientist – LMS 905Computational Regulatory Genomics – Long-range transcriptional regulationFixed Term, 3 years£35,340 - £38,181 pa inclusive*London, UKA 3 year postdoctoral is available at the MRC London Institute of Medical Sciences (LMS) and Imperial College London to work in the Computational Regulatory Genomics group headed by Professor Boris Lenhard. The group studies gene regulation at the genome-wide level using methods of computational genomics and epigenomics. The group is now also applying experimental techniques of regulatory genomics, and has developed the first low-input cap analysis of gene expression methodology to allow mapping promoters and enhancers from as little as 1000 cells. The interests of the group range from investigating sequence signals and chromatin organisation at core promoter regions to revealing rules of communication between core promoter and distal regulatory elements and how they give rise to elaborate spatiotemporal expression patterns in development. The group has a track record of excellence and innovation in computational genomics, with numerous publications in top-tier journals and extensive international collaboration (for further information please visit https://lms.mrc.ac.uk/research-group/computational-regulatory-genomics/ ).We are looking for an enthusiastic, creative, ambitious and skilled postdoctoral scientists with background in biological sequence analysis, comparative genomics and/or analysis of next-generation sequencing-based experiments. You will need a PhD (or equivalent) in a relevant subject. A competitive publication record in the field is expected, as well as knowledge of molecular biology and evidence of proficiency in the computational analysis of biological data or the development of computational tools for given purpose. Proficiency in bioinformatics programming is required. The post is open for candidates wishing to pursue a career in computational genomics in collaboration with experimental researchers, and to candidates who wish to combine experimental and computational approaches in their own work. For candidates wishing to combine experimental and computational techniques, we are looking for expertise in experimental genomic techniques. The project will broadly focus on studying long-range transcriptional regulation and promoter-enhancer interactions in Metazoan genomes. Its aims will be to understand how genes interact with their regulatory elements at long distances, how long-range regulatory elements evolve and/or how they are affected by extracellular signals during development and differentiation. The research is expected to be based on novel approaches for the analysis of original and published comparative genomic, epigenomic, transcription factor binding and chromatin conformation experimental to investigate long-range regulation at genome-wide level. The post supports post-doctoral scientists in early or changed career training and helps establish them as successful research scientists in their chosen field. It comes with funding for computing, consumables, training courses and travel.LMS is an institute funded by MRC and is a division of the Faculty of Medicine at Imperial College London. Based on the Hammersmith Hospital Campus in West London, the LMS has first class facilities and provides investigators from clinical and basic science backgrounds with the opportunity to pursue innovative, multidisciplinary research within the established clinical base of Imperial College. For more information, visit www.lms.mrc.ac.uk.Informal enquiries should be sent to [email protected] For full details of this post visit https://mrc.tal.net/vx/lang-en-GB/appcentre-1/candidate/postings/1018 and upload your CV and research statement not longer than two pages, submitted as a separate document. The research statement should outline your most important achievements to date and a brief vision of your present research interests and future career.The MRC London Institute of Medical Sciences is a research institute within UK Research andInnovation. UK Research and Innovation is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at www.ukri.org Closing date for all completed applications is 13 September 2018*Salary quoted is inclusive of London weighting. Additional allowances comprise a £1,000 lump sum Settlement Allowance plus a yearly Training Allowance of £850 in the first year, paid in monthly instalments. The Training Allowance increases to £1,300 in year two, and £1,800 in the third year.

8002| university of Bath| Research Associate (Fixed Term) in Microscopy & Instrumentation| Open source hardware could bring about a step change in science and medicine, by making high quality instruments more widely available and easier to customise. We are looking for a talented researcher with (or soon to be awarded) a PhD in Physics, Engineering, or a related discipline, to develop microscopes and related instruments for malaria diagnostics and biophysics research, using 3D printing and easily obtained components to make these instruments small, inexpensive, and easily replicated around the world. This post is funded by two EPSRC projects, focusing on medical diagnostics and biophysical research respectively. Both projects rely on the same core technology - inexpensive, automated microscopy based on the Openflexure Microscope design. You will develop novel instruments using this underlying technology, and automate them to change the way we carry out both diagnostic tests and scientific experiments.Malaria affects hundreds of millions of people per year, and is often diagnosed with manual microscopy, which is labour-intensive and hard to quality-control. This project, funded by the Global Challenges Research Fund, will use automated, low-cost, 3D printed microscopes to provide accurate and high-throughput diagnosis for Malaria in ODA countries. The project team includes the Universities of Bath and Cambridge, and Ifakara Health Institute in Tanzania, and there will be opportunities to visit both partners. We will build on our open source hardware designs to develop low cost, fully automated microscope hardware that can acquire images consistently and efficiently. The ultimate goal is that these microscopes can be produced locally, building skills and jobs across the developing world, and reducing dependency on expensive, slow, and unreliable supply chains.In collaboration with the Cicuta lab in the University of Cambridge, you will also enable high-throughput "behavioural phenotyping" of malaria parasites - following the lifecycle of the parasite as it invades blood cells and replicates. These experiments are laborious and time-consuming to do by hand on conventional microscopes, and thus cannot keep pace with modern gene editing techiques - automating and parallelising these experiments will allow us to understand the genetics of malaria parasites better, ultimately leading to new ways to control the disease.This post is fixed term for 2 years. Physics at the University of Bath is a research-led Department, ranked highly in the UK in the latest Research Excellence Framework, and the University recently attained a Gold rating in the Teaching Excellence Framework. Both the Department and the University are committed to providing a supportive and inclusive working environment, with an active Athena Swan programme and opportunities for researchers to receive training, mentorship, and career development.Informal enquiries are encouraged, and should be directed to Dr Richard Bowman ([email protected]). Interview Date: Thursday 20 September 2018 Closing Date: Sunday 09 September 2018

7984| University College Dublin, UCD School of Chemical and Bioprocess Engineering| UCD Research Fellow, UCD School of Chemical and Bioprocess Engineering (Temporary)| The UCD Energy Institute is one of the leading research institutes for Energy Systems Integration. The Energy Systems Integration Partnership Programme (ESIPP) is an €11million research project co-funded by Science Foundation Ireland, Industry and Philanthropic donations which brings together researchers from various disciplines to address the challenges of the energy industry in the global transition to more sustainable energy systems. As part of this project the role which natural gas and renewable gas will play in supporting this global transition is being investigated.An expert in the field of physical-based modelling is required to model gas networks and examine their integration and interaction with other aspects of the energy system including electricity, water, climate and economics. Candidates should be familiar with at least one modelling software package, such as Matlab, GAMS or equivalent, or specialised gas network simulation packages e.g. Synergi, Pipeline studio or equivalent.Salary: €53,249 - €56,378 per annum.Appointment on the above range will be dependent upon qualifications and experience.Closing Date: 17.00hrs (Local Irish Time) on 23rd August 2018.Applications must be submitted by the closing date and time specified. Any applications which are still in progress at the closing time of 17:00hrs (Local Irish Time) on the specified closing date will be cancelled automatically by the system. UCD are unable to accept late applications.UCD do not require assistance from Recruitment Agencies. Any CVs submitted by Recruitment Agencies will be returned.Prior to application, further information (including application procedure) should be obtained from the Work at UCD website: https://www.ucd.ie/workatucd/jobs/.

7990| UKRI Medical Research Council, Laboratory of Molecular Biology| Postdoctoral Scientist - PNAC - Dr Roger Williams - LMB 891| Postdoctoral Scientist – PNACStarting Salary £30,464 - £33,305 per annum 3 Years Fixed TermMRC Laboratory of Molecular Biology, Cambridge, UKApplications are invited for a Postdoctoral Scientist position in the Group of Dr Roger Williams to carry out structural and functional studies of mTOR-containing complexes. The programme involves cryo-electron microscopy, X-ray crystallography, H/D exchange mass spectrometry, as well as other biophysical and biochemical approaches.You should have a PhD (or be due to complete a PhD within 6 months of applying) in biology, biochemistry, biophysics, chemistry or a related discipline and should have a strong interest in structural approaches in molecular biology. You should also have experience in one or more of the following techniques: cryo-electron microscopy, X-ray crystallography, enzyme kinetics, mass spectrometry or biochemistry of signal transduction. Successful applicants will be awarded a 3 year Career Development Fellowship/MRC Postdoctoral Training Scheme position. The fellowship is a Training and Development position for a Postdoctoral Scientist who has recently completed their doctoral studies, or is moving into a new research discipline.This 3 year post is funded by Cancer Research UK to focus on the structural biology of mTORC1 assembled with its regulators on lysosomal membranes.The MRC Laboratory of Molecular Biology is a research institute within UK Research and Innovation (UKRI). UKRI is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at www.ukri.org.Working for UKRI MRC provides a whole host of benefits including a defined benefit pension scheme, excellent holiday entitlement (40 ½ days including bank holidays and privilege days) and Benenden Healthcare membership. You will also have access to employee shopping/travel discounts, on site sport and social facilities, as well as salary sacrifice cycle to work schemes and childcare vouchers.Final appointments will be subject to a pre-employment screening.The Medical Research Council is an Equal Opportunities Employer who participates in the Disability Confident scheme.

8022| University of Florence, LENS| Postdoctoral Researcher - Single Molecule Manipulation and imaging| The Single Molecule Biophysics group at LENS (European Laboratory for Non-linear Spectroscopy, www.lens.unifi.it/bio), University of Florence, Italy, is seeking a highly motivated and independent postdoctoral scientist with proven academic track record and interest in interdisciplinary biophysics research.The Single Molecule Biophysics group develops novel single molecule manipulation and imaging tools to address outstanding biological questions. Research topics include the influence of force on biological processes, gene expression regulation, and molecular mechanisms of motor proteins functioning (Gardini et al., Nature Communications 9, 2844, 2018; Tempestini et al., NAR 46, 5001-5011, 2018; Capitanio et al., Nature Methods 9, 1013–1019, 2012; Capitanio et al., PNAS 103, 87-92, 2006).Applications from scientists with a predominantly physics background and research experience in optics, microscopy, and related disciplines will be considered. Previous experience in development of optical setups and/or single-molecule techniques will be advantageous.The successful candidate will work on the development of techniques for the manipulation (optical tweezers) and imaging (fluorescence/scattering microscopy) of single biological molecules. We aim at further developing a unique in vitro optical tweezers technique that we developed in our lab (Capitanio et al., Nature Methods, 2012). This will be applied to study motor proteins involved in intracellular transport and molecular mechanisms underlying mechanotransduction. Mechanotransduction, i.e. the conversion of mechanical forces into biochemical and biomolecular signals, is at the basis of many biological processes fundamental for the development and differentiation of cells, for their correct function and for the development of pathologies. The appointed candidate will also work on combining advanced single molecule manipulation and imaging techniques for the study of mechanically-induced regulation of gene expression in living eukaryotic cells.Informal enquiries and applications can be submitted to Dr. Marco Capitanio ([email protected])Interested applicants should submit:- a short cover letter setting out your reasons for applying for the post and highlighting the particular skill and experience which you feel you would bring to the role.- a CV, which should include research experience, publications, and names of referees.Selected applicants will be contacted for an interview. References will only be requested forcandidates shortlisted for interview.Please apply at your earliest convenience and before 20 September 2018.

8015| Queen Mary University of London, School of Biological and Chemical Sciences| Postdoctoral Research Assistant| A Postdoctoral Research Assistant position is available at Queen Mary University of London (QMUL) in the group of Prof. Alexander Ruban, to work on the project "Quantification of the mechanisms of light tolerance that determine growth and productivity in plants and algae".The proposal combines two state-of-the art clusters of approaches. First is the use of the plant and algal mutants in combination with the full physiological characterisation of photosynthetic membrane activity, composition and structural analysis (using freeze fracture electron microscopy) combined with immunogold labelling and the magnetic bead pull-down methods. Second, the use of the novel pNPQ technology for assessment of plant tolerance to light that will focus upon the quantification of the contribution of NPQ and D1 protein turnover to light tolerance in plants and diatom algae, differentiation of the effects of donor and acceptor site photodamage and its role in plant and algal growth and productivity. Queen Mary is one of the top research-led universities in the UK and was ranked 9th among the UK multi-faculty universities in the Research Excellence Framework (REF 2014). All postdoctoral researchers are part of the QMUL Doctoral College, which provides support with high-quality training and career development activities.The postdoctoral research will focus on development of plant and algal growth and stress techniques in order to achieve selective expression of specific minor photosynthetic antenna complexes important in protection against excess light; isolation of these complexes and their characterisation. In addition, the experimental work on establishment the relationship between photoprotective and repair mechanisms in the photosynthetic membrane of plants and algae will be carried out. The research will also be undertaken to establish the molecular basis for the relationship between photoprotection and productivity of the photosynthetic mechanisms. The equipment and all materials are available within the PI’s laboratory and the School of Biological and Chemical Sciences.The ideal candidate should have a PhD in Plant and Algal Physiology and/or Plant and Algal Biochemistry. Previous experience in growing plants and algae, isolation and characterisation of membrane proteins, electron microscopy is essential. A track record in high-quality original research and peer-reviewed publishing is essential. Duties may also include limited teaching activities (supervision of project students, tutorials, and lab demonstrating), which will enhance postdoc's experience and qualification.This is a full-time, fixed term post available for 1 year in the first instance. The start date is 01/10/2018 or as soon as possible hereafter. The salary is £33,615 - 37,411 per annum and is inclusive of London allowance. Benefits include 30 days annual leave and a pension scheme. Candidates must be able to demonstrate their eligibility to work in the UK in accordance with the Immigration, Asylum and Nationality Act 2006. Where required this may include entry clearance or continued leave to remain under the Points Based Immigration Scheme.Informal enquiries for further information are welcomed and may be made to Prof. Alexander Ruban, email: [email protected] further information about the School, please see http://www.sbcs.qmul.ac.uk. To apply, please click on the link.Application enquiries should be directed to [email protected] The closing date for applications is 16 September 2018. Interviews will be held shortly thereafter. Valuing Diversity & Committed to Equality

7993| University of Oxford, School of Geography and the Environment| Research Associate in Water Resource Systems Modelling| The Environmental Change Institute (ECI) in the University of Oxford successfully led the major research project MaRIUS: Managing the Risks, Impacts and Uncertainties of droughts and water Scarcity within the UK Droughts on Water Scarcity Programme. During the MaRIUS project, a national water resource system model was developed using the WATHNET modelling system.The WATHNET model is being extended to cover all of England and Wales in support of national water resources assessment and investment planning. MaRIUS has now received additional funding to support dissemination and stakeholder uptake of the research. A team of researchers are making datasets available and providing case studies, demonstrations and training.We are seeking to appoint a Research Associate who will work with us to complete the WATHNET model, generate innovative research results and help to make the system available to practitioners in government and industry.The successful candidate will have experience of the implementation of water resources system models. You will have a flair for the development of innovative system modelling solutions. You must have a Doctorate and excellent programming skills, demonstrated through the implementation of system models, and ideally experience of optimisation, distributed computing and visualisation. You will have a sound understanding of drought risk analysis, uncertainty analysis and decision analysis and preferably innovative experience of applying these methodologies in the context of water management and water infrastructure planning decisions. You will be expected to publish their research work in the international academic literature. You will participate enthusiastically in the multidisciplinary research consortium, including engagement with project stakeholders in government and industry.This is a fixed-term post for 12 months in the first instance.For an informal discussion about the post, contact Professor Jim Hall, via his PA: [email protected] for this vacancy are to be made online. Click here for more information https://data.ox.ac.uk/doc/vacancy/136350.htmlYou will be required to upload a CV and supporting statement as part of your online application.The closing date for applications is 12.00 noon on Friday 7 September 2018, and interviews will be held week commencing Monday 17 September 2018.Vacancy ID: 136350 Closing Date: 07-Sep-2018 Contact Email: [email protected]

8008| Universities Federation for Animal Welfare| Part Time Sub Editor| The Universities Federation for Animal Welfare (www.ufaw.org.uk) is a highly respected charity, based in Wheathampstead, Hertfordshire, promoting advances in animal welfare through science and education internationally. An exciting opportunity to assist the Chief Executive and other scientific staff with the production of the UFAW Handbook on the Care and Management of Animals used in Research, and other books or other publication edited or produced by UFAW to assist in reviewing submissions to the Journal Animal Welfare.The successful applicant for this post will have an understanding of the scientific process and experience in research and writing or editing scientific papers, articles or books in the biological or veterinary sciences. The person is therefore likely to possess a veterinary degree or higher research degree (eg PhD in biological sciences), and/or some relevant post-doctoral or graduate experience. Key characteristics are, an understanding of animal welfare science; Good writing, editing and communication skills are essential; preferably experience of reviewing and/or editing scientific papers; attention to detail; an understanding of reputational and libel risks; and an ability to deal sensitively when dealing with authors.This is a 3 year contract for 2 days a week. Additional hours may be required as agreed. Some home-working may be possible.Salary £27,285 - £28,936 plus London allowance (£2,134) pro-rata according to qualifications and experience. Email Jane Moorman ([email protected]) for information Full Applications to arrive on or before noon, 21 September 2018 Interview Date: 12 October 2018

8013| Huazhong University of Science and Technology, School of Mechanical Science and Engineering| Postdoctoral Position in Additive Manufacturing| 1. Introduction of Supervisor Prof. Haiou Zhang, expert in mechanical engineering, academic leader of State Key Laboratory of Digital Manufacturing andEquipment Technology. D.E of Tokyo University, Deputy Director of Foundry Branch of China Mechanical EngineeringAssociation, Director of Foundry Branch of Mechanical Manufacture and Automation, Vice-Chairman of China 3D PrintingIndustry Alliance, academic committee member of China Additive Manufacturing Industry Alliance, Chief Director of HubeiSpecial Processing Academic institution. Prof. Haiou Zhang was awarded Top Ranking Prize of Japan Mould TechnologyInstitution. The research findings had been listed in Research Contribution Price Catalog of Japan Powder Technology Institution.Prof. Haiou Zhang was recommended to HUST through “113 Talented People Project” in 1998, and then started to lead theteam to conduct the research in composite additive manufacturing theory, processing, data processing, software designing,detecting control and other key technologies and to conduct research in digital manufacturing equipment in the past 20 years.His research findings had won the Gold Medal at the Geneva International Technology Invention Exhibition in 2017. Hisresearch findings has been applied in many fields, and has completed the 3D printing of core components such as aero enginecasings, aero-engine transitions, aircraft hang-ups, ship propellers, frogs, nine-node joints, and turbo pumps of large internationalcompanies such as General Electric Company, Airbus, Commercial Aircraft Corporation of China Ltd., AEEC Xi'an Aero-engine Ltd., AVIC Chengdu aircraft Industrial (Group) Co., LTD., China Shipbuilding Industry Corporation ( CSIC ), ChinaRailway Engineering Corporation, China Construction Steel Structure Corp. Ltd., and Gree Electric Appliances Inc.2. QualificationsTo be considered for the project, candidates must:1) Under the age of 35.2) Have a doctoral degree in materials science and technology, institutional design, testing and control, software for additivemanufacturing, robot and composite CNC machine tools, artificial intelligence and unmanned trolleys / unmanned aircraft,ultrafast lasers.3) Published academic papers in major international journals or conferences, and have relevant research experience.4) Have strong theoretical foundation, practical ability, independent research ability, and good team spirit.3. Benefits1) Salary: 190,000-210,000RMB per year.2) Flexible work practices and overseas exchange study opportunities.4. Application Documents1) CV2) Representative papers or patents3) Research plan5. How to ApplyPlease send the application documents to the following email address: [email protected]

8020| Medical Research Council, London Institute of Medical Science| MRC Postdoctoral Research Scientist| MRC Postdoctoral Research ScientistFunctional Gene Control groupFixed term, 3 yearsMRC Band 4 Salary £35,340 - £38,181 pa inclusive*London, UKA postdoctoral position is open in the Functional Gene Control group at MRC London Institute for Medical Sciences (LMS) led by Dr Mikhail Spivakov (https://lms.mrc.ac.uk/research-group/functional-gene-control/). We combine experimental and computational approaches to study the logic of gene regulation, with a particular emphasis on the function of DNA elements such as enhancers in gene regulatory networks and on human primary cells as experimental systems. Examples of our recent work include Freire-Pritchett et al., eLife 2017, Javierre et al., Cell 2016, and the Chicago R package for Capture Hi-C analysis (Cairns et al., Genome Biol 2016).You will have a PhD (or equivalent), a strong background in a biomedical science or quantitative discipline (mathematics, statistics, physics, computer science), as well as prior experience in generating and/or interrogating data from high-throughput genomics assays. Competence in the analysis of chromosomal interactions and cis-regulatory networks is particularly relevant, and a track record in devising novel experimental and/or computational techniques is desirable. The ideal applicant will have a dual wet- and dry-lab expertise, but strong candidates from either one of these backgrounds are also encouraged to apply. Our group has recently moved to MRC LMS from the Babraham Institute in Cambridge. For more information about our research and publications while at Babraham, please see http://regulatorygenomicsgroup.org. You will join an international, multidisciplinary team within a collaborative and stimulating research environment, with strong links with other groups at the LMS and beyond.Informal inquiries can be addressed to Dr Mikhail Spivakov ([email protected]).For full details of this post and to complete an online application, visit https://mrc.tal.net/vx/lang-en-GB/mobile-0/appcentre-1/brand-3/xf-c2d556c41018/candidate/so/pm/4/pl/1/opp/898-MRC-Postdoctoral-Research-Scientist-LMS-898/en-GB and upload your CV, names and contacts of two scientific references along with a covering letter stating why you are applying for this role (providing evidence against the requirements of the job as per the job description and person specification). Please quote reference number LMS – 898.Closing date: 6 September 2018The MRC London Institute of Medical Sciences is a research institute within UK Research and Innovation. UK Research and Innovation is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at www.ukri.org Final appointment will be subject to pre-employment screening*Salary quoted is inclusive of London weighting. Additional allowances comprise a £1,000 lump sum Settlement Allowance plus a yearly Training Allowance of £850 in the first year, paid in monthly instalments. The Training Allowance increases to £1,300 in year two.

8003| University of British Columbia - Okanagan, Food Systems PRISM Lab| POST-DOCTORAL POSITION – LCA OF SUSTAINABLE AGRI-FOOD TECHNOLOGY AND MANAGEMENT ALTERNATIVES| The Food Systems PRISM Lab is seeking a highly qualified and highly motivated post-doctoral fellow to contribute to research and research management in the field of agri-food life cycle assessment.Located at the University of British Columbia (Okanagan Campus), Canada, the Food Systems Priority Research for Integrated Sustainability Management Laboratory (Food Systems PRISM Lab – www.prismlab.weebly.com) is a hub for cross-cutting research at the intersection of food system sustainability measurement and management. Under the direction of Dr. Nathan Pelletier (Endowed Chair in Bio-economy Sustainability Management and NSERC/EFC Industrial Research Chair in Sustainability), the lab undertakes a broad array of inter-related research activities including:- life cycle assessment of conventional and alternative agricultural, horticultural and livestock production technologies - identification of sustainability best management practices for agri-food supply chains- evaluation of environmental and economic payback times for renewable energy, waste valorization, precision agriculture, advanced digital technologies and other green technology options for food system applications- development of spatially-resolved life cycle-based decision support tools for agri-food system stakeholders- development of the Canadian Agri-food Life Cycle Data Centre (a publicly available LCI database)- direct industry engagement and knowledge translation and transferThe successful candidate for this position MUST possess:- a mature foundation in life cycle assessment theory and practice, including data quality and uncertainty assessment- a strong publication record and interest in further research in the field of agri-food life cycle sustainability modelling, in particular with respect to the above-mentioned areas of research- a keen interest in contributing to mentoring and co-publishing with a large cohort of research assistants and graduate students (MSc and PhD) while developing extensive lab management, research supervision, grant writing, and industry engagement credentials- excellent English language skillsCompensation: The successful candidate will receive a salary of $70,000 annually (renewable for up to two years)Interested candidates should send ALL of the following materials to Dr. Nathan Pelletier (nathan.pelletier(at)ubc.ca). Incomplete applications will not be considered.(1) a cover letter summarizing the applicants qualifications with respect to the above specified requirements(2) a complete scholarly curriculum vitae(3) up to three relevant peer-reviewed publicationsOnly short-listed candidates will be contacted for an interview and letters of reference. The position is available beginning January 2019 until filled.

8016| Leiden University Medical Center| Postdoctoral fellow| Vacancy number: D.18.MV.CV.11Closing date for application: until September 9th, 2018Postdoc m/f, LeidenThe position:How would you like to work with state-of-the-art viral vector systems and genome modification tools? We’re looking for a Postdoctoral fellow to join our research group investigating gene transfer and gene editing strategies for correcting muscle progenitor cells from patients with Duchenne muscular dystrophy. Your profile:• Has obtained a PhD in Biomedical sciences, Protein engineering, Biochemistry or in a similar research field within the past 5 years.• Possesses solid theoretical knowledge and practical experience in protein modelling, expression, purification and characterization. • Has previous experience with molecular and cellular biology techniques.• Is proficient in both written and spoken English.• Has shown the capacity for independent writing of scientific articles and reports.• Is meticulous in documenting and tracing reagents and experimental results.• Can supervise and manage personnel in coordination with other group members.• Experience with NGS technologies (e.g. data analysis) is advantageous.What we offer:You will be employed on the basis of a 36-hour week. The appointment is initially for one year with the possibility to be extended by one additional year, for the duration of the project. Your salary will depend on your qualifications and experience, with a maximum of € 4,216 gross per month based on a full time position (scale 10 of the Collective Labour Agreement for University Hospitals). The organisation:The LUMC is a center for medical innovation that aims to improve patient care through leading international research. To provide our patients with a safe and friendly environment, we need doctors, medical care specialists, support staff and academic researchers. Within the Department of Cell and Chemical Biology, the Virus & Stem Cell Biology Section focuses on developing viruses and stem/progenitor cells into therapeutic agents for the treatment of human diseases. The Section is further divided into sub-groups. This research project will be carried out in the Genome editing sub-group. All research in the Department is performed in collaboration with groups within and outside the LUMC.Further information:A detailed description of this position can be found on www.lumc.nl (select ‘Job opportunities’). If you have any questions or would like to have more information about this position, please contact Manuel A.F.V. Gonçalves, Associate professor, Department of Cell and Chemical Biology, telephone +31 (0)71 526 92 37, e-mail [email protected] You may also contact Josephine M. Janssen, Research Technician, Department of Cell and Chemical Biology, telephone +31 (0)71 526 92 38, e-mail [email protected] How to apply:If you are interested in this position, please complete the application form (http://bit.ly/2HaclAf) before September 9th, 2018. You may also apply through the website www.lumc.nl/vacatures.

7992| Trinity College Dublin, Centre for Transport Research| Post doctoral position - Health impacts of Nitrogen Dioxide with particular emphasis on vulnerable groups| Candidates are invited to apply to join the Centre for Transport Research in the Department of Civil, Structural & Environmental Engineering at Trinity College Dublin as a Postdoctoral Researcher, to start in September 2018 or as soon as possible thereafter. The successful candidate will work on a research project on the health impacts of NO2 funded by the Environmental Protection Agency. Ideally the candidate should have a PhD in engineering, statistics, environmental engineering/science, health studies or other relevant discipline. Salary: €37,383 per yearDuration: 16 months.Project OverviewEvidence of association between ambient concentrations of NO2 and a range of health impacts has strengthened in recent years. Transport is responsible for a significant proportion of NOx emissions, and diesel engines, in particular, generate high levels. Diesel cars have become extremely popular in Ireland since 2008 when the government changed car taxation policy to focus no longer on engine size but to CO2 emissions of the vehicle. While anecdotal evidence suggests that diesel car sales may be slowing down, the large numbers of diesel vehicles in the existing fleet are still a cause for concern in relation to NO2 emission levels. Some of the key objectives of the project are:1. Using currently available air pollution measurements and recent research results on the influence of meteorological and source parameters (including transport vehicle and population mobility demands), the project will identify a set of characteristics for the locations in Ireland that are at most risk of experiencing high levels of NO2.2. Using the Health Service Executive (HSE)-Primary Care Reimbursement Service (PCRS) prescribing database, the project will establish much needed baseline data linking NO2 levels with the prescription of drugs used to treat asthma and chronic obstructive airways disease.3. The Irish Longitudinal Study on Ageing (TILDA) database (~8,500 participants) will be explored to investigate if relationships between prevalence of respiratory symptoms in vulnerable groups e.g. the elderly and the socio-economically deprived and NO2 levels exist, within database constraints. 4. Policies and strategies being implemented by other countries to bring NO2 within compliance levels will be examined to explore their potential effectiveness and efficiency for implementation in Ireland.Interested applicants should apply by sending a CV and a 500 word document, summarizing their interest and demonstrating what their background and experience would bring to the project, to [email protected]

8023| University of Sheffield, Human Communication Sciences| Research Associate| The Department of Human Communication Sciences, University of Sheffield wishes to recruit a Postdoctoral Associate for a fixed term 1 year appointment. You will be an early career researcher with a PhD in developmental psychology/language research or a related field. Working within the Developmental Speech, Language and Literacy research cluster, you will play a key role within two active projects within the cluster. The two projects both focus upon language assessment for children in digital contexts. Within project one you will contribute directly to the extension or further development of the multilingual receptive vocabulary screener (e.g. item development); see http://www.vocabularyapp.org/. For the second project, you will be assessing children with and without language difficulties, to evaluate the impact of modality: paper versus digital, on assessment performance.The position will be co-supervised by Dr Jenny Thomson (https://www.sheffield.ac.uk/hcs/staff/thomson) and Dr Silke Fricke (https://www.sheffield.ac.uk/hcs/staff/fricke). The project is funded by a specific named legacy administered by the Heather van der Lely Foundation, with Dr. Hilary Gardner acting as project consultant. Anticipated start date: October 1st, 2018. For more information, please contact Jenny Thomson: [email protected] RequirementsYou will have (or be expected to obtain) a PhD in psychology, speech science, linguistics, education or a related field. You should have experience of conducting assessments with children in school settings and confidence in interacting with digital devices such as tablets. You will have a strong knowledge of language development and familiarity with linguistic concepts including word frequency and age of acquisition. Also desirable is knowledge of multilingual and/or cross-linguistic language development. In addition to English, you may be a speaker or have knowledge of one or more of the following languages: Polish, Czech, Slovak, Mandarin Chinese, Portuguese, German, Turkish, Punjabi, Urdu, Welsh.The successful candidate would need to travel to participating primary schools for data collection purposes. We’re one of the best not-for-profit organisations to work for in the UK. The University’s Total Reward Package includes a competitive salary, a generous Pension Scheme and annual leave entitlement, as well as access to a range of learning and development courses to support your personal and professional development.We build teams of people from different heritages and lifestyles from across the world, whose talent and contributions complement each other to greatest effect. We believe diversity in all its forms delivers greater impact through research, teaching and student experience.To find out what makes the University of Sheffield a remarkable place to work, watch this short film: www.youtube.com/watch?v=7LblLk18zmo, and follow @sheffielduni and @ShefUniJobs on Twitter for more information.

8001| University College Dublin, UCD School of Business| UCD Post-doctoral Research Fellow Level 1 or Level 2 (MIS), UCD School of Business (Temporary)| This role is within Work Package 7 (WP7), which will deal with implementing the causality dynamics framework using an agent-based modelling (ABM) approach. A professional software development company, Assist, will build this into a software application. This integrated modelling approach will be uses for the analysis of external and internal drivers influencing the performance of food value chains and demonstrate options for improved business strategies. It will also explore the impact of public regulations (quotas, subsidies, public procurement policies etc.) and private initiatives (certification, Corporate Social Responsibility, marketing, retailer standards, fair trade etc.), which have shaped these food chains to assess the conditions under which these interventions enhance (or do not enhance) resilience, integrity and sustainability. The focus of WP7 will be on unfair trading practices (UTPs).This position may be appointed at either Post-doctoral Fellow level 1 or level 2 depending on the relevant qualifications of the successful candidate.Salary: €36,854 - €37,383 per annumClosing Date: 17.00hrs (Local Irish Time) on Thursday, 23rd August 2018.Applications must be submitted by the closing date and time specified. Any applications which are still in progress at the closing time of 17:00hrs (Local Irish Time) on the specified closing date will be cancelled automatically by the system. UCD are unable to accept late applications.UCD do not require assistance from Recruitment Agencies. Any CVs submitted by Recruitment Agencies will be returned.Prior to application, further information (including application procedure) should be obtained from the Work at UCD website: https://www.ucd.ie/workatucd/jobs/.

8018| The Institute of Cancer Research| Genome Analysis Postdoctoral Training Fellow - Systems and Precision Cancer Medicine Team| The Institute of Cancer Research, London, is one of the world’s most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. We provided the first convincing evidence that DNA damage is the basic cause of cancer, laying the foundation for the now universally accepted idea that cancer is a genetic disease. Today, The Institute of Cancer Research (ICR) leads the world at isolating cancer-related genes and discovering new targeted drugs for personalised cancer treatment.Under the leadership of our Chief Executive, Professor Paul Workman FRS, the ICR is ranked as the UK’s leading academic research centre. Together with our partner The Royal Marsden, we are rated in the top four cancer centres globally.The ICR is committed to attracting, developing and retaining the best minds in the world to join us in our mission – to make the discoveries that defeat cancer.We seek a motivated, experienced and independent Postdoctoral Training Fellow with extensive next generation sequencing data analysis skills to play a key role in facilitating the research of the Systems and Precision Cancer Medicine Team (Team Leader Anguraj Sadanandam). Our interdisciplinary lab focuses on personalized medicine and companion diagnostics using cancer subtypes and evolution by integrating multi-omics (molecular and metabolism) and phenomics (phenotypes) data. We perform this by integrating computational biology skills (in-house developed cutting-edge computational and statistical tools) with wet-lab science by cross-comparing and integrating high-throughput data (including whole tumour and single cell omics data) between patients and in vivo and in vitro models. To this end, we have classified different tumor types including breast cancer cell lines, and pancreatic and colorectal tumours and cell lines into distinct molecular and/or drug response subtypes (PNAS 2012, Nature Medicine 2011, 2013 and 2015, and Cancer Discovery 2015). We also develop and publish next generation statistical tools for genome-phenome analysis and other purposes (Nyamundanda et al., Scientific Reports 2017, bioRxiv 2017; Ragulan et al., bioRxiv 2017; Eason et al., BMC Bioinformatics 2018). We also make our tools available through github (https://github.com/syspremed). For more information please visit: http://www.icr.ac.uk/our-research/researchers-and-teams/dr-anguraj-sadanandam and http://www.icr.ac.uk/news-archive/scientists-uncover-four-different-types-of-bowel-cancerThe successful candidate will help us in using novel pipelines of computational methods to integrate and analyze next generation sequencing and other profile data from 400+ patient samples and clinical information. This also includes high-throughput cell lines based drug response data. The candidate will assist the entire lab to manage the large-scale data and local systems administration. Our lab has access to the ICR’s high performance computing facility for data processing. They will also be engaged in collaborative research projects within the lab and beyond, potentially resulting in high profile publications. They will be encouraged to develop their own research interests in areas related to the Centre's activities.Applicants should possess a Ph.D. (or equivalent) in bioinformatics, computational biology, genomic sciences, statistics, mathematics, physics, life sciences or other related fields with extensive experience in bioinformatics and next generation omics data analysis. Experience in analyzing massively parallel sequencing data in cancer is essential as well as strong analytical skills. Excellent organisational, writing and communication skills are also required. Knowledge in molecular biology and related life sciences field is essential.This is an excellent opportunity for an independent and motivated individual to work in an exciting and highly collaborative environment. The position is offered on a fixed-term contract of 1 year with a starting salary within the range of £30,715 - £41,550 per annum inclusive based upon relevance of skills and experience.Informal enquiries can be made to Dr Anguraj Sadanandam ([email protected]). Please DO NOT send your application to Dr. Sadanandam, formal applications must be submitted online.To apply please follow the link to the ICR's career page, complete an online application form, attaching your CV and covering letter (addressing with specific examples where you meet the person specification and incl. the names and addresses of two referees)