8557| University of Canterbury, College of Engineering| Post-Doctoral Fellow Human Interface Technology Laboratory (HIT Lab NZ)| • Full-time at 37.5 hours per week (1.0 FTE)• 2 Year fixed term opportunityWhat You Will DoThe Human Interface Technology Lab New Zealand (HIT Lab NZ) at the University of Canterbury in Christchurch, NZ has an immediate opening for a postdoctoral researcher.This two-year position will focus on the design, implementation, evaluation, and deployment of multisensory feedback techniques in immersive Virtual Reality (VR) systems. The work will involve research into methods for generating and delivering multisensory cues in concert to produce user experiences that mimic real-world situations in high fidelity.In addition, novel user interface techniques focusing on expressive, non-fatiguing interaction that can be used to support long-duration VR use will be designed and evaluated.Who You AreThe successful candidate must have completed a PhD in a VR-related field, such as computer science, and have a history of successful work in conducting user studies in VR, as evidenced by publications in appropriate venues.Significant mentoring of the successful candidate will be provided by senior academic staff, giving the candidate a solid research foundation essential for future academic success. The candidate will be given significant freedom to help manage and guide the more-junior members of the research team, and as such, build skills in project and team management.Results of the work will be submitted for publication in leading journal and conference venues, and there is significant budget for travel to present the work.The candidate will also have the opportunity to assist in delivering courses within our Master of Human Interface Technology programme, covering topics around usability, prototyping, and evaluation.Who You Will Work WithThe HIT Lab NZ is one of the leading research labs focused on human-centred design of technology to support people in all facets of their lives. We put the person first, and then apply an appropriate mix of technology for that person in the context of the tasks they are doing. The Lab is very international in flavour, and interdisciplinary in thought and approach.For more information on the HIT Lab NZ, please visit: http://www.hitlabnz.orgWhy UCThe University of Canterbury is committed to promoting a world-class learning environment through research and teaching excellence, and has a vision statement of "People Prepared to Make a Difference". You will have the opportunity to work alongside members of a diverse academic community and enrich your own professional and personal development.For information about the range of fantastic benefits that UC offers including flexible work practices, study opportunities and generous superannuation and leave provisions, please visit us: http://www.canterbury.ac.nz/joinusNeedless to say, New Zealand provides an unbelievable setting to perform this work, and the HIT Lab NZ values a balanced approach to work and life. Christchurch is the prime spot to launch excursions around New Zealand, as it has an international airport, and is in the middle of South Island. This provides easy access to beaches, pristine forests with extensive, well-maintained walking and mountain-biking tracks, excellent skiing in winter, and easy connections to other locations such as Australia. Christchurch is also very family friendly.The closing date for this position is: August 17th, 2019 (Midnight NZ time) ApplyApplications for this position are submitted online and should include a cover letter (describing background, suitability for the position, your recent and future research projects), a curriculum vitae which includes a list of relevant research publications, and the names and contact details of two referees. Please ensure your application is uploaded as a single pdf file and that the file name is your surname only.We are happy to answer your queries in relation to the application process, please forward these to Lorna Grubb, Recruitment Coordinator, [email protected] further information specifically about the role, please contact Chris Buyarski, [email protected] University of Canterbury is an EEO employer and actively seeks to meet its obligation under the Treaty of Waitangi.

8548| Grenoble Ecole de Management| Post-Doctoral Researcher within the “Energy for Society” Chair| Grenoble Ecole de Management (GEM) has earned both national and international recognition. More than just a school, GEM represents an open-ended laboratory through which 8,000 students and 500 employees learn and work every day to solve complex problems and overcome major challenges for businesses and society.The school is accredited by AACSB, EQUIS and AMBA. Its programs are regularly ranked by major international economic newspapers and magazines. As an institution for higher education (EESC) affiliated with the Grenoble Chamber of Commerce and Industry, GEM is a founding member of the GIANT Innovation Campus in Grenoble as well as an associate member of the Université Grenoble Alpes Community.With almost 100 permanent researchers distributed into eight teams, strong doctoral programs (270 doctoral students), a large number of European and national research grants, substantial corporate and institutional partnerships, and a vibrant, cooperative research culture, GEM is proud to be featured today among the leading management research organizations in Europe in terms of research output as well as impact. Research at GEM builds on four large thematic, collaborative platforms to address important societal issues: Health, Digital Transformation, Energy, and Society and Inclusive Sustainability.The post-doctoral researcher will be attached to the “Energy for Society” Chair, which is supported by the GEM Foundation, School for Business and for Society (under the aegis of the Fondation de France)The ambition of the GEM Foundation is to connect research and society by funding new research, disseminating results towards the largest audience, and using results to improve training for students. In this sense, it is a true knowledge co-building tool, especially through the research Chairs that it supports.Missions:- The post-doctoral researcher will participate in two research projects funded by the sponsors of the “Energy for Society” Chair, each project having a different project administrator.- The first project aims at building a project together with the research team and the sponsors about the co-creation of innovative energy services in the energy sector. Several orientations are possible depending on the interests of the applicant: How will the value of a co-created service be divided? How will the replicability of the co-created service be ensured in order to develop a viable business model? This project will represent the biggest part of the workload.- The second project aims at evaluating the impact of new uses on business models in the energy sector. This project is based on hypothetical choice experiments. The post-doctoral researcher will support the research team in the analysis of results and implications on business models for the tested solutions.Required skills:- Knowledge of qualitative data collection (e.g., semi-directive interviews) and of data analysis via qualitative data analysis software (such as Atlas TI or nvivo)- High research potential demonstrated by the ability to publish in international peer-reviewed journals- Ability to work among an interdisciplinary research team- Good mastery of English (written and spoken)- Good mastery of French (written and spoken)Practical information:-To apply, you have to hold a doctorate degree in management sciences with, if possible, a specialization in organization theory or business models.- Start as of September 2019 for a 1 year period, one time extendable- Position grid Post-doc- Salary: depending on profile and experience

8540| UKRI Medical Research Council, Laboratory of Molecular Biology| Investigator Scientist - Structural Studies - Dr Madan Mohan - LMB 1109| Investigator Scientist Starting Salary £30,914 - £39,381 per annumFixed Term until 31st December 2024MRC Laboratory of Molecular Biology, Cambridge, UKWe have an Investigator Scientist position available (to be filled as soon as possible) for an experienced and highly motivated computational biologist in the group of Dr. M. Madan Babu at the MRC Laboratory of Molecular Biology in Cambridge, UK. This post will be part of a newly established Centre for Adipocyte Signaling (ADIPOSIGN) funded by a recent major grant from the Novo Nordisk Foundation. ADIPOSIGN is run by four partners with highly complementary expertise in the fields of adipocyte biology, transcriptional regulation, signal transduction, physiology, and computational systems biology.You will have a PhD in computational biology/bioinformatics/systems biology/network biology with extensive post-doctoral experience and proven track record in integrative systems biology and multi-omics network biology. Your primary role as a computational biologist will be to identify, develop, implement and use computational biology methods to integrate, mine, visualize and analyse multiple large-scale omics datasets for hypothesis generation and creation of network models of obesity. You will establish computational pipelines to organise and interrogate multiple omics datasets as well as develop and maintain a community web resource for the consortium. The position will involve some traveling for collaborative purposes. You will be working in a dynamic and highly collaborative environment, and will be expected to communicate complex informatics principles, methods, analyses and results to scientists from diverse backgrounds in the consortium. You will enjoy a rich and collaborative intellectual environment and interactions with a dynamic interdisciplinary team working on a variety of topics, both computational and experimental within the LMB and through the ADIPOSIGN consortium.The MRC Laboratory of Molecular Biology is a research institute within UK Research and Innovation (UKRI). UKRI is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at www.ukri.org.Working for UKRI MRC provides a whole host of benefits including a defined benefit pension scheme, excellent holiday entitlement (40 ½ days including bank holidays & privilege days) and Benenden Healthcare membership. You will also have access to employee shopping/travel discounts, on site sport and social facilities, as well as salary sacrifice cycle to work schemes and childcare vouchers.To apply and access full details of the vacancy please visit our job board at https://mrc.tal.net/vx/lang-en-GB/appcentre-1/tmpwid-7c20_1d396251-2252-4867-8a5b-3b9423c960ff/candidate/postings/1247.If you are unable to apply online please contact us at [email protected] date: 21st July 2019 Final appointments will be subject to a pre-employment screening.The Medical Research Council is an Equal Opportunities Employer who participates in the Disability Confident scheme.

8569| City of London, Guildhall School of Music and Dramas/Barbican Centre| Post Doctoral Research Fellow| Starting salary of £17,115 (FTE £34,230) per annum (inclusive of London Weighting), dependent on experience and performancePart time, 17.5 hours per week:The Barbican, Europe’s leading Arts and Conference Centre, presents an unparalleled variety of performing and visual arts of world class calibre, as well as hosting extensive commercial activity. The Guildhall School of Music & Drama is a UK Higher Education Institution with degree-awarding powers. It combines world-class specialist conservatoire tuition with a highly innovative portfolio of Bachelor’s and Master’s degrees, and a burgeoning research culture. Since the Barbican and the Guildhall School launched a creative learning partnership in 2009, more than 42,000 people including children, young people, families, community groups and artists have participated in our learning programmes and activities, while more than 300,000 have enjoyed our programme of free events produced in collaboration with our partnersAs part of a fast-growing programme of critical evaluation and research in the area of the social impact of the performing arts, Barbican-Guildhall Creative Learning seeks to appoint to a brand-new Postdoctoral Research Fellowship. In addition to pursuing his or her own research, the successful candidate will lead on capturing and interpreting the learning generated from a newly formed National Development programme. Part of Creative Learning’s Schools and Colleges strand, this work will explore and evaluate ways of catalysing, convening and strengthening collaborative partnerships between arts centres nationally, and between arts centres and the school communities that they serve. The overarching aim is to enhance young people’s access to arts and cultural learning across a range of geographic contexts; this two-year part-time fellowship represents an exciting opportunity for a researcher to be embedded within the project, contribute to its development and especially its evaluation, and thereby shape future policy at a multi-organisational and potentially national level. The ideal candidate will have a proven research interest in (and perhaps direct experience of) cultural learning programmes or similar, a good understanding of the formal education sector, and the ability to build rapport with a broad range of stakeholders. As this role is not office based and involves working nationally, we welcome applications from researchers based outside London.Closing date: Midday, Wednesday 17 July 2019. First interviews are scheduled for the afternoon of 23 July 2019, and the morning of 25 July 2019.All applications must include a completed application form. Late applications will not be accepted. To apply, please visit www.cityoflondon.gov.uk/jobs. Alternatively, please contact 020 7332 3978 (24hr answerphone) quoting reference number GS498. A minicom service for the hearing impaired is available on 020 7332 3732. The City of London Corporation is committed to Equal Opportunities and welcomes applications from all sections of the community.

8575| University of Oxford, MRC Weatherall Institute of Molecular Medicine| Postdoctoral Scientist in Leukaemia Stem Cell Biology| MRC Weatherall Institute of Molecular MedicineUniversity of OxfordGrade 7: £32,236 - £39,609 per annumThis is an exciting opportunity for a highly motivated and ambitious Postdoctoral Scientist to join the research group of Professor Adam Mead at the MRC Weatherall Institute of Molecular Medicine (WIMM). The position is available fixed-term for 3 years, funded by CRUK.The Mead laboratory is focused on studying normal and malignant haematopoiesis, through the application of single-cell genomics and stem cell biology techniques. The overarching aim of this exciting project is to identify new therapeutic approaches for children with Juvenile Myelomonocytic Leukaemia, a poor prognosis blood cancer of childhood. The successful candidate will lead this work, utilising novel single-cell multi-omic approaches, together with cutting-edge in vivo models. You will hold a PhD (or near to completion: thesis submitted) in a relevant area, with experience in transcriptome analysis, FACS analysis and cell culture techniques. A strong publication record in high-impact peer-reviewed journals is necessary, as well as the ability to work independently and as part of a team. You will have excellent communication and organisational skills, with the ability to manage and independently drive, innovate and complete your own research and associated activities.Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application.

8544| University of Bordeaux, Rhythmology and cardiac modeling institute (IHU-Liryc)| Post-doctoral fellowship| Description: In the context of a newly awarded project from the European Research Agency Cardiovascular Disease (ERA-CVD) program and funded through the French National Research Agency (ANR), the patho-physiology group of the Electrophysiology and heart modeling institute (https://www.ihu-liryc.fr/en/) is seeking a highly qualified motivated individual to fill a Post-Doctoral Fellowship position in the area of translational cardiac electrophysiology. The project integrates European collaborators, the Leibniz Institute of Photonic Technology (Germany) and the Medical University of Vienna (Austria), to develop a medical catheter integrating a novel combination of optical modalities with electrical mapping and ablation to diagnose, guide treatment and validate treatment efficacy in a single system. The optical configuration will be a first-of-its-kind in cardiac electrophysiology mapping, enabling high resolution tissue characterization at bio-molecular and structural levels for mapping of cardiac disease and improve perception of heart tissue vulnerable to arrhythmic behavior. Responsibilities: We are looking for a Postdoctoral Fellow with interest in pursuing research projects within one or more of the following areas:• Comparative functional-substrate mapping to evaluate the interplay between electrical dynamics and tissue remodeling in disease.• Development and optimization of structural imaging of cardiac disease in large mammalian tissue.• Support of preclinical evaluation and clinical translation of catheter prototype testing in electrophysiology studies.Mentoring and Context: The candidate, whose principal investigator will be Dr. Richard Walton, will work in a rich environment, including the use of chronic large mammalian models of cardiac disease, in vivo cardiac mapping, ex vivo heart perfusion and opto-electrical mapping and in vitro structural imaging. The project takes place in direct collaboration with local clinical and European partners. The site includes three dual camera optical mapping systems, microCT, histology and immunology suite, operation rooms and an angiography catheter laboratory, all available on a single platform dedicated to large mammalian translational research. Training can be provided in each of these areas.Qualification: Candidates should hold a PhD degree in physiology, biomedical sciences, biomedical engineering or biomedical imaging. Motivation and rigor combined with a capacity to work as a team are expected. Experience in one or more of the following areas are highly desirable: • Optical mapping• Computed tomography (micro) • Image processing• Heart perfusion, with emphasis on large mammalian preparations• Scientific programming (MATLAB, Python, PV wave)Appointment Length and Duration: 2-year post-doctoral fellowship with potential for extension to three years. Start date, from September 2019.Location: Electrophysiology and heart modeling institute (IHU-Liryc), Bordeaux, France. Contact: For more information or to apply for the position (including an up-to-date CV and motivation letter), please contact Dr. Richard Walton ([email protected]).

8560| Ohio State University, Department of Biological Chemistry & Pharmacology| Postdoc position in Alzheimer's disease research| We are seeking highly motivated individuals (two or thee) to join our lab as postdocs. Projects include the role of neurotrophic factors in neuropathology including Alzheimer’s disease and spinal cord injury. Additional projects include drug discovery for Alzheimer’s disease and understanding the role of metabolic disruption in microglial function in Alzheimer’s disease. We are looking for scientists with a background and training in neurosciences, cell biology, biochemistry, and/or molecular biology with solid first author publication(s). Salary is based on the NIH postdoc pay scale ( the 1st yr is $50,004) plus full benefits that includes medical, dental, and vision care.Columbus, the capital of Ohio state, is a mid-size city in the US. Living is easy in Columbus with low crime rate and without much car traffic even during rush hour. People in Columbus are also very nice and welcoming compared to those in big cities. Cost of living is also modest with apartment rental prices ranging from $900 to $1200 a month for 2 bedrooms. The quality of public primary and secondary schools is also outstanding. Interested applicants should submit Curriculum Vitae, a brief description of your research interests, and contact information of two or three references to: [email protected] For more information, see https://medicine.osu.edu/bcpharm/directory/faculty-directory/sung-ok-yoon/Pages/index.aspx

8566| King's College London, Department of Chemistry| Research Associate in Chemical Biology| The research group of Dr. Manuel Mueller in the Department of Chemistry at King’s College London is looking to hire a postdoctoral researcher. Our recently formed lab develops and applies chemical biology strategies to investigate how proteins are controlled by post-translational modifications. In particular, we are interested in modifications of the protein backbone and their potential to control the structure and function of biomedically important proteins in unique ways. In this context, we are looking for a postdoctoral researcher to develop a multidisciplinary platform to identify and characterise cellular proteins subject to backbone modifications.The candidate should hold a PhD in Biochemistry or a related subject with an emphasis on chemical biology, protein engineering and/or proteomics, and have a strong interest in protein biochemistry. The candidate should have a proven track record of research excellence as evidenced by publications in peer-reviewed journals. She/he should have a fascination for interdisciplinary research, work well in a small team and have excellent communication skills.Please include a letter of motivation, your CV including a list of publications and contact information of 2 references in your application. For an informal discussion to find out more about the role please contact Dr. Manuel Mueller at [email protected] selection process will include a panel interview and a presentation.

8539| Université catholique de Louvain - UCLouvain, Louvain Centre for Toxicology and Applied Pharmacology - LTAP| Postdoc Position: Macrophages in Mesothelioma| The Louvain Centre for Toxicology and Applied Pharmacology (LTAP) is seeking for an enthusiastic, highly motivated and skilled candidate with a background in toxicology, pathology, tumor biology or immunology for Senior Scientist (post-doctoral) role in our mesothelioma program.The selected candidate will be focused in work leading to the characterization of mesotheliomagenic macrophages. She/he will effectively collaborate within our research center and supervise young scientists and technicians working in the project.We offer an inspiring multicultural environment, constructed of our enthusiastic, highly skilled and experienced personnel. LTAP has established working links with local immunologists and medical doctors and other groups from French and American universities. Brussels is a very good city to live in. It offers a safe living environment, cultured atmosphere and a central localization in Europe.Qualifications:PhD in toxicology, immunology, molecular/cell biology, or cancer biology.Knowledge on macrophage biology, high-throughput experimentation, large data analysis or lipidomics is positively evaluated.Strong hands-on technical skills (e.g. primary cell isolation and culture, flow cytometry, live cell imaging).Effective written and spoken English language skills.Excellent teamwork skills.The Université catholique de Louvain (UCLouvain; www.uclouvain.be) involves more than 30,000 students of 123 different nationalities and a staff of about 5,800 teachers, researchers and administrative and technical collaborators. UCLouvain is ranked first among Belgian francophone universities. Research is one of UCLouvain’s main activities with €242M in annual research and development investment. More than 1000 research contracts are signed every year with universities, public institutions and private companies. UCLouvain is actively involved in 176 projects within FP7 and in already 98 Horizon 2020 projects.The Louvain Centre for Toxicology and Applied Pharmacology (LTAP, www.toxi.ucl.ac.be/accueil.html) was established in 2009 at UCLouvain to conduct advanced research on the effects of xenobiotics on human health in IREC. LTAP addresses both intended (applied pharmacology) and adverse health effects of chemicals (toxicology). The centre integrates interdisciplinary expertise (clinical, analytical, experimental, epidemiological sciences) and is actively engaged in commissioned projects and research for European, national and regional government bodies, major companies, trade associations. Our group has broad expertise in studying the toxic mechanisms of inhaled particles and was among the very first worldwide (2005) to report on the respiratory toxicity of multi-walled carbon nanotubes (MWCNT). The Centre is fully equipped and has expertise to conduct human and clinical studies. LTAP combines wide experience in research and publishing with youthful flair and imagination. We published 244 papers between 2014 and 2018 (44 of which in journals with an impact factor >5). Over the same period, research expenditures reached 3.225.000 euros.

8547| University of Warwick, Physics| Research Fellow| Ref: 100371-069Fixed-term contract for 12 Months (Dependant on the start date the fixed-term contract ending no later than 31 July 2020) Full-time, 36.5 hours per week Project title: Microfluidic techniques for correlating sperm DNA integrity with its motility on singe cell level The Department seeks to appoint a Research Fellow to work on the above interdisciplinary project in collaboration with the University of Sheffield Medical School. The successful candidate will be working on development and implementation of a new microfluidic technique to study correlations between sperm DNA damage and motility on singe cell level. Applicants should possess or be very close to obtaining a doctorate in physics, cell biology or a related field. You should have a strong background in optical microscopy and image analysis, applied to soft matter or biophysics experiments. You will be an excellent communicator capable of working effectively both independently and as part of the research team. You will possess excellent planning and time management skills to ensure your research objectives are achieved effectively. Pay level will be commensurate to prior experience. If you have not yet been awarded your PhD but are near submission or have recently submitted your PhD, any offers of employment will be made as Research Assistant on level 5 of the University grade structure (£29,515). Upon successful award of your PhD and evidence of this fact, you will be promoted to Research Fellow on the first point of the level 6 of the University grade structure (£30,395). Please direct all informal inquiries to Dr. Vasily Kantsler ([email protected])Ref: 100371-069To apply, please visit: https://atsv7.wcn.co.uk/search_engine/jobs.cgi?owner=5062452&ownertype=fair&jcode=1809210&vt_template=1457&adminview=1Closing Date28 Jul 2019The University Values Diversity

8538| University of Cambridge, MRC Toxicology Unit| MRC Postdoctoral Fellow| The Medical Research Council Toxicology Unit is an internationally renowned institution focussed on the delivery of field-changing mechanistic insights into toxicology and disease. The Unit is equipped with state-of-the-art facilities including super resolution microscopy and offers excellent opportunities for postdoctoral development. The Unit is part of the University of Cambridge; it is currently located at Leicester and will physically relocate to Cambridge in 2020, therefore the first part of the project will be conducted at Leicester.Applications are invited for an MRC Postdoctoral Fellow (PF) to join the laboratories of Willis and MacFarlane within the Unit’s Cross-Unit Programme: Mechanisms of Fibre Toxicity. The focus of the programme is to carry out research into the molecular pathways triggered by exposure to toxic fibres that leads to mesothelioma, for further information visit: https://www.mrc-tox.cam.ac.uk/research/mechanisms-fibre-toxicityThe aim of the project is to generate a detailed adverse outcome/toxicity pathway which fully describes in molecular terms the changes which lead to the development of MPM following exposure of mice to CNTs with different aspect-ratios and chemically-modified fibres. In the longer term, this information will be used to obtain novel biomarkers of exposure to monitor workers in facilities which use/produce CNTs (including low and middle income countries, LMICS). It will also inform about the potential hazards associated with the use of new nanofibres and promote the concept of “safe by design” to those developing such materials. The project will identify the contribution of dysregulated transcription, and translation, RNA-interactome to adverse events that follow nanofibre exposure.This is a three year training and development position. We support postdoctoral scientists in these positions with a range of formal and on-the-job training to ensure you receive the training relevant to your role and identify additional training to help support your future career. Applicants must have (or be in the final stages of receiving) a PhD in a relevant discipline and have experience in molecular and cell biology. Experience in RNA biology, epigenetics, transcription profiling, cancer cell biology and working with animal models is desirable. The ability to publish high quality research in a peer reviewed journal; to be able to work both independently and as part of a team, together with excellent communication and problem solving skills are required.Further information on the Toxicology Unit can be found at https://www.mrc-tox.cam.ac.uk/Closing date: Sunday 21st July 2019.

8552| Media Research Council| Programme Manager - Animal Welfare (maternity cover)| Science-led and evidence-based, the NC3Rs is the UK’s national organisation for the 3Rs, established in 2004 to accelerate the development and uptake of new models and tools that replace, reduce or refine the use of animal in research and testing. We have shown that science and technology focused on minimising animal use or improving animal welfare, can deliver benefits to human health, protection of the environment and business opportunities. The NC3Rs is primarily funded by Government and has an annual budget of approximately £10 million. Its activities are divided between its role as the UK’s major 3Rs research funder and programmes led by its own team of scientists. Further information can be found at www.nc3rs.org.uk. Role of the Programme ManagerImproving research animal welfare is a key part of the NC3Rs remit and we support this through funding research, developing online resources and publications, and organising symposia and workshops. Activities focus on specific areas (e.g. refinement of rodent epilepsy models) through to those which have a broader impact (e.g. non-aversive methods of handling mice). All vertebrate laboratory animal species are included in the NC3Rs refinement portfolio and the Programme Manager will be required to work with scientists, animal technicians and veterinarians from academia and industry to develop and promote opportunities to minimise pain, suffering, distress or lasting harm. The main responsibilities of the Programme Manager are expected to include:• Keeping abreast of the latest scientific and technological developments that could compromise animal welfare or be exploited for refinement benefits so that the NC3Rs is able to respond accordingly. • Identifying specific areas of concern and leading the development of an evidence base to address these - this typically involves organising expert working groups, collating and analysing data, and preparing material for publication in the peer-reviewed literature. • Facilitating the uptake and implementation of approaches which improve animal welfare - this typically involves organising workshops and symposia, developing content for the NC3Rs website, and presenting at national and international conferences. • Providing oversight on refinement research awards funded by the NC3Rs, including through our CRACK IT open innovation schemes, to ensure that there is maximal dissemination of outputs. • Supporting the NC3Rs 3Rs peer review and advice service provided to the major UK bioscience funders, focusing on reviewing research proposals involving the use of non-human primates, cats, dogs, horses and pigs. • Qualifications and work experience • PhD in a biological science, ideally with in vivo experience. • A qualification in animal welfare science or animal behaviour is desirable. • Excellent understanding of the use of animals in research and a demonstrable commitment to the 3Rs.• Experience of reviewing research proposals and/or project licence applications.• The ability to collaborate and effectively network with stakeholders from a diverse range of roles and levels of seniority.• Experience of organising scientific events.• Ability to represent the NC3Rs at national and international meetings.• Excellent communication skills, both written and verbal. • Excellent strategic thinker, with the ability to identify, analyse and propose solutions to varied and complex scientific problems.• Proven ability to prioritise and plan workload to meet multiple and/or tight deadlines without compromising quality or working relationships.• Excellent interpersonal skills and the ability to work well as part of a dynamic team.Additional informationThe successful candidate will be subject to security checks.The closing date for applications is Thursday 1 August.Please visit the NC3Rs website for further information, to apply please visit https://mrc.tal.net/vx/appcentre-ext/candidate/post/2349/en-GB Please ensure you include a copy of your CV and a covering letter explaining how you meet the criteria listed in the person specification.

8541| UKRI Medical Research Council, Laboratory of Molecular Biology| Investigator Scientist - Structural Studies - Dr Madan Mohan - LMB 1111| Investigator Scientist Starting Salary £30,914 - £39,381 per annumFixed Term until 31st December 2024MRC Laboratory of Molecular Biology, Cambridge, UKWe have an Investigator Scientist position available (to be filled as soon as possible) for an experienced and highly motivated computational biologist in the group of Dr. M. Madan Babu at the MRC Laboratory of Molecular Biology in Cambridge, UK. This post will be part of a newly established Centre for Adipocyte Signaling (ADIPOSIGN) funded by a recent major grant from the Novo Nordisk Foundation. ADIPOSIGN is run by four partners with highly complementary expertise in the fields of adipocyte biology, transcriptional regulation, signal transduction, physiology, and computational systems biology.You will have a PhD in computational biology/bioinformatics/systems biology/network biology with extensive post-doctoral experience and proven track record in integrative systems biology and multi-omics network biology. Your primary role as a computational biologist will be to identify, develop, implement and use computational biology methods to integrate, mine, visualize and analyse multiple large-scale omics datasets for hypothesis generation and creation of network models of obesity. You will establish computational pipelines to organise and interrogate multiple omics datasets as well as develop and maintain a community web resource for the consortium. The position will involve some traveling for collaborative purposes. You will be working in a dynamic and highly collaborative environment, and will be expected to communicate complex informatics principles, methods, analyses and results to scientists from diverse backgrounds in the consortium. You will enjoy a rich and collaborative intellectual environment and interactions with a dynamic interdisciplinary team working on a variety of topics, both computational and experimental within the LMB and through the ADIPOSIGN consortium.The MRC Laboratory of Molecular Biology is a research institute within UK Research and Innovation (UKRI). UKRI is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at www.ukri.org.Working for UKRI MRC provides a whole host of benefits including a defined benefit pension scheme, excellent holiday entitlement (40 ½ days including bank holidays & privilege days) and Benenden Healthcare membership. You will also have access to employee shopping/travel discounts, on site sport and social facilities, as well as salary sacrifice cycle to work schemes and childcare vouchers.To apply and access full details of the vacancy please visit our job board at https://mrc.tal.net/vx/lang-en-GB/appcentre-1/tmpwid-7c20_1d396251-2252-4867-8a5b-3b9423c960ff/candidate/postings/1248 If you are unable to apply online please contact us at [email protected] date: 21st July 2019 Final appointments will be subject to a pre-employment screening.The Medical Research Council is an Equal Opportunities Employer who participates in the Disability Confident scheme.

8576| University of Manitoba/CancerCare Manitoba, Pharmacology and Therapeutics| Postdoc or Research Associate in Cancer Biology| The Haigh lab recently located to the Research Institute in Oncology and Hematology (RIOH) that is part of CancerCare Manitoba and the University of Manitoba. We are presently seeking junior and/or senior postdoctoral researchers or research associates interested in joining our lab. Our group is presently interested in further investigating the role that ZEB and SNAI family of transcription factors as well as VEGF signalling play in normal hematopoiesis and leukemia transformation (see some representative publications below). We expect that interested candidates would be willing and able to apply for their own local/national and international funding after initial 3 years of support and have competitive CVs. The following skill set would be important (but not essential) for successfully contributing to our lab’s primary research efforts:1) Experience in working with mouse and/or human models of hematopoiesis and leukemic transformation or other cancer models.2) Experience using multicolour FACS and cytometric analysis of mouse/human hematopoietic system.3) Previous experience working with large datasets generated by RNA/ChIPseq or single cell sequencing approaches.4) Experience working with CRISPR/Cas9 gene editing systems and retro/lentiviral delivery of gRNA and shRNA cargoes to hematopoietic progenitors/cell lines.5) Strong background in molecular biology and/or protein biochemistry.6) Previous experience in working with human ES/iPS cells.Sample Haigh Lab Publications:1) Goossens et al., Blood. 2017 129(8):981-990.2) Li et al., Blood. 2017 129(4):460-472.3) Goossens et al., Nature Communications. 2015 6:5794.4) Haenebalcke et al., Cell Reports. 2013 3(2):335-41.5) Maes et al., EMBO J. 2010 29(2):424-41.6) Drogat et al., Blood. 2010 116(12):2141-2151.The population of Winnipeg, Manitoba, Canada is about 700,000. The city has excellent facilities for most cultural, sporting, and recreational activities. Winnipeg is home to the Winnipeg Symphony Orchestra, Manitoba Opera, Royal Winnipeg Ballet, Manitoba Theatre Centre, and Winnipeg Art Gallery. Professional sports teams include Blue Bombers football, Winnipeg Jets hockey, and Valour Football Club, Winnipeg’s professional soccer club. Outdoor recreational activities are found throughout the province of Manitoba in all seasons. Winnipeg is also highly affordable compared with other major Canadian cities.The University of Manitoba is strongly committed to equity and diversity within its community and especially welcomes applications from women, racialized persons, Indigenous Peoples, persons with disabilities, persons of all sexual orientations and genders, and others who may contribute to the further diversification of ideas. If you require accommodation supports during the recruitment process, please contact U of M’s Equity, Diversity and Inclusion Facilitator, Valerie Williams at [email protected] or 204-474-8371. All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.Application materials, including letters of reference, will be handled in accordance with the protection of privacy provision of The Freedom of Information and Protection of Privacy (Manitoba). Please note that curriculum vitae may be provided to participating members of the search process. Initial CIHR project based funding is for a three-year period and salary level will be commensurate with qualifications and experience. Initial start date is negotiable, and review of applicants will begin in July, 2019 and will continue until position is filled.Interested Candidates should send their CVs and the names and contact information of three references to the following e-mail address:Associate Professor Jody Jonathan HaighDepartment of Pharmacology and TherapeuticsRady Faculty of Health SciencesUniversity of ManitobaSenior ScientistResearch Institute in Oncology and Hematology (RIOH)CancerCare Manitoba, ON5029E-mail: [email protected]

8578| University of Lund, Department of Clinical sciences| Postdoc in bone tissue engineering| We are recruiting highly motivated scientists at Post-doctoral level! Applicants with an international research experience and strong background in molecular biology, 3D printing, bone formation/regeneration, tissue engineering are encouraged to apply. With a 30min direct connection to Copenhagen airport, Lund is an accessible university city of international reputation. You will be most welcome in a young, friendly and dynamic environment. Please provide your CV, motivation statement and up to 3 referees at: [email protected] INFORMATIONThe lab: The successful candidates will be part of the novel laboratory for Cell, Tissue and Organ engineering. The laboratory is part of the Wallenberg Centre for Molecular Medicine (WCMM LU), at the Lund Faculty of Medicine (https://www.med.lu.se/english). Focusing on regenerative medicine (regeneration, replacement and repair), WCMM LU is part of a national effort to strengthen Sweden as a world-leading life science nation (https://www.med.lu.se/wcmm).Our lab aims at deciphering the cellular & molecular mechanisms occurring during phases of bone formation/repair. Using state-of-the-art 3D culture systems, death-inducible human mesenchymal lines and tissue engineering protocols, we focus on studying processes of cartilage/bone/bone marrow establishment in human(ized) contexts. Compiled knowledge will be used for the design of cell-based but cell-free extracellular matrices, to be used as smart-materials for skeletal repair. As such, the lab covers both fundamental and translation research aspects. More information available on our website: www.bourginelab.comThe University: The lab is located within the BioMedical Center of the Faculty of Medicine and is part of Lund University (Sweden). The university was founded in 1666 and is repeatedly ranked among the world’s top 100 universities. With 42 000 students and 7 400 staff based in Lund, Helsingborg and Malmö, Lund is the second largest university of Sweden.The Faculty of Medicine as part of Lund University is responsible for education and research within medicine and healthcare. Our academic programs are closely linked with the healthcare system and are firmly anchored in the faculty’s strong research tradition. Our research spans a broad field within experimental preclinical research, near-patient clinical research and health sciences research. The Faculty of Medicine, is a knowledge-intensive meeting place for students, teachers and researchers from all over the world.Position: Postdoc position in tissue engineering/regenerative medicineProject: The candidate will exploit novel human death-inducible cell lines and 3D systems for the engineering of extracellular matrices customized in composition and shape. Those cell-based but cell-free grafts will be characterized and validated in various animal models of bone repair. The candidate will target the GMP and scaled-up production of such materials, toward its pre-clinical validation. The candidate is also expected to decode the cellular/molecular events driving bone formation in this model. The project combined both key translational and fundamental features.Ideal profile: You are a freshly graduated PhD looking for a post-doctoral experience to complement your existing skills/background. You have strong experience in tissue engineering, and knowledge on bone development, biology and regeneration. You are familiar with cell culture and engineering techniques, flow cytometry. The laboratory will offer you robust training in human cellular biology, engineering of human cells/tissues/organs, as well as in manipulation of 3D culture systems. Required skills include an excellent speaking/writing English levels and capacity to work with animals. Experience in molecular biology, 3D culture, confocal microscopy or 3D printing is a strong asset.

8564| Long Island University, College of Veterinary Medicine| Postdoctoral Fellow, Bio Med Science| Title: Postdoctoral FellowDepartment: Bio Med ScienceCampus: Brookville, New YorkDate Posted: 06/17/2019Salary: Commensurate with experienceFLSA: ExemptStarting Date: As soon as possibleContact: Please submit an online applicationThe College of Veterinary Medicine at Long Island University (Post Campus) invites applications for the position of Postdoctoral Fellow. The selected candidate will be required to have hands-on experience with:Human cell culture:• Setting up cell culture for primary and cancer cell lines, transient and stable transfection, lentiviral transduction.Cell culture based assays:• MTT assay, cell proliferation assay, colony formation assay, invasion assay, wound-healing assay, flow cytometry, immunofluorescence staining.Small animal handling:• Breeding and maintenance of mice colonies, genotyping for knockout and transgenic mouse models.Animal associated procedures:• Generation of sub-cutaneous and orthotopic xenograft models, generation of bone metastatic model using intracardiac injection, intraperitoneal injections, necropsy and tissue collection, immunohistochemistry of tissue sections.Small animal imaging:• Luciferase imaging of xenograft and transgenic mouse models.Molecular biology:• DNA and RNA isolation and estimation, Agarose gel electrophoresis, Cloning, PCR, real time PCR, ChIP, ChIP-Seq.Biochemistry:• Protein isolation and estimation, SDS-PAGE, western blotting, immunoprecipitation, in vitro and in vivo biochemical assays.Immunohistochemistry:• Tissue processing, histology, H&E staining, IHC staining and calculationsMicroscopy:• Bright field and fluorescence microscopy, confocal microscopy.Spectroscopy:• UV-Vis spectroscopy and spectrophotometry.Bioinformatics:• Primer designing, sequence alignment, preliminary analysis of ChIP-seq and RNA-Seq data, meta-analysis of patient datasets available in GEO, oncomine and other related databases.Mentoring:• Mentoring undergraduate and graduate students in basic skills for cancer and cell biology techniques and small animal handingPublishing:• Gathering and interpreting experimental data, preparing reports and manuscripts.Other duties as assignedTraining, Skills, Knowledge, Experience:• The successful applicant will need to have at least one year of experience directly related to the current job assignment.• The successful applicant will need to demonstrate ability to plan and organize assigned activities and ability to work effectively with faculty, staff, and administrators as necessary.• The successful applicant will need to demonstrate the proven ability to conduct research and to independently carry out major projects of importance to the University and the community.• The successful application should have a strong and consistent publication record in cancer biology.Education Requirements:• Minimal qualifications include a PhD in natural science, or a health-related field from a college or university of recognized standing, at least one years of postdoctoral experience.Application Instructions:Please send cover letter and resume.LIU is an equal opportunity employer. LIU is committed to extending equal opportunity in employment to all qualified candidates who can contribute to the diversity and excellence of our academic community. LIU encourages applications from all qualified individuals without regard to race, color, religion, genetic information, sexual orientation, gender and/or gender identity or expression, marital or parental status, national origin, ethnicity, citizenship status, veteran or military status, age, disability or any other basis protected by applicable local, state or federal laws. Hiring is contingent on eligibility to work in the United States.To applyhttps://apptrkr.com/1502253

8559| Nottingham Trent University, School of Science and Technology| Research Fellow in Imaging for Security and Medical Applications| Post Ref No: 06485Contract type: Fixed term – 3 years Hours: 37 hours per week College of Science and TechnologySchool of Science and TechnologySalary: £33,199 - £37,345 per annumGrade: HCampus: CliftonClosing date: 21 July 2019As part of a highly experienced and award winning team, led by Distinguished Prof. Paul Evans, you will benefit from a world leading record of accomplishment in the field of X-ray imaging. The Imaging Science Group at Nottingham Trent University (NTU) has a fulltime postdoctoral Research Fellow post available initially for 3 years, with possibility of extension. The post is funded by a Royal Society and Wolfson Foundation research grant. A Queen’s Anniversary Prize has recognised the group’s achievements in 2016, which highlighted their world class research and industrial impact. In addition, Prof. Evans received the IOP Gabor medal in 2017. The aviation security work has attracted around £10 million research funding from UK and US governments over recent years.The successful candidate will be based at the NTU Clifton campus in Nottingham and will work in a multidisciplinary team, initially helping to develop new approaches to enhance aviation security systems. As a part of the research group, you will benefit from access to state of the art and unique laboratory facilities at NTU. Access is also available to other facilities at collaborating institutions; including government labs, industry and other research-intensive universities. The group’s aim in security screening is to develop detection principles and techniques that are applicable to a wide range of threats and in particular explosives/precursors. The work focuses on identifying threats and contraband within passenger luggage and postal packages, without manual searches or handling the items. Other areas of interest include medical diagnostics and process control. This exciting, multidisciplinary project would suit a highly motivated individual interested in any of the following areas: 3D/tomography/X-rays/X-ray diffraction (XRD) and also machine learning applied to the preceding areas, image analysis, material science, simulation and modelling, physics and engineering. NTU has been awarded University of the Year by The Guardian in 2019, The Times in 2018, and Times Higher in 2017.Entry requirementsThis programme seeks candidates with a PhD degree and strong theoretic abilities in a relevant subject area i.e. physics/maths, imaging science, X-ray diffraction (XRD) simulation, engineering computing/machine learning; or an equivalence in industry experience. EligibilityThis role does not meet the minimum requirements set by UK Visas & Immigration to enable sponsorship of migrant workers. Therefore, we cannot progress applications from candidates who require sponsorship to work in the UK.Contact Prof Paul Evans for an informal discussion: [email protected]

8546| Quadram Institute Bioscience| Research Scientist| Applications are invited for an enthusiastic and motivated Research Scientist with Molecular Microbiology expertise to join the Quadram Institute Bioscience (QIB), in Norwich, UK.The role:The successful applicant will work within an interdisciplinary team of scientists engaged in the investigation of the molecular basis of Listeria monocytogenes survival and metabolism. The aim is to study the functional genomics and transcriptional response of Listeria to environmental stress that enables persistence. Population genomics, functional genomics, and gene expression approaches will be used to identify genomics signatures that lead to persistence and increased risk to assist in the development of diagnostics and interventions aimed at eradicating the pathogen from food and the environment. You will work closely with bioinformaticians and molecular biologists to deliver multidisciplinary science. This role is an exciting opportunity for training and career development.QIB provides a vibrant and stimulating setting composed of multiple research teams working on microbial genomics, molecular epidemiology, microbial communities and food science. We offer the chance to work with world leading, cutting edge technologies both in Molecular and computational biology and give you the opportunity to broaden your skills using open source technologies within a bioinformatics context. You will gain experience of working with Big Data and have the opportunity to publish excellent science in leading peer-reviewed journals.The ideal candidate:The ideal candidate will have a strong background in molecular microbiology – genetics and genomics, with a PhD in the subject, or related discipline. Experience of Listeria genetics or bioinformatics is highly desirable. You will also have excellent communication and interpersonal skills, as engagement with scientists in related projects throughout the Institute and beyond is an important feature of the role.Additional information:Salary on appointment will be within the range £31,625 to £38,575 per annum depending on qualifications and experience. This is a fulltime post for a period of 3 years.For further information and details of how to apply, please visit our web site https://jobs.quadram.ac.uk or contact the Human Resources team on 01603 450462 or [email protected] quoting reference 1003672.We are committed to equal opportunities and welcome applications from all sectors of society. The Institute supports equality of opportunity within the workplace and expects all employees to share and display these values. To support our commitment, we have a range of family, faith and diversity friendly working arrangements to help all staff achieve excellence in their area of work.As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy.

8568| University College Dublin, UCD School of Computer Science| UCD Post-doctoral Research Fellow Level 2, UCD School Computer Science (Temporary, 24 Month Post)| Applications are invited for a temporary post of a UCD Post-doctoral Research Fellow Level 2 within UCD School of Computer Science.This is an advanced research focused role, building on your prior experience as a post-doctoral fellow, where you will conduct a specified programme of research supported by research training under the supervision and direction of Prof. M-Tahar Kechadi. The primary purpose of the role is to develop new or advanced research skills and competences, on the processes of publication in peer-reviewed academic publications and scholarly dissemination, the development of funding proposals, and the supervision and mentorship of graduate students along with the opportunity to develop your skills in research led teaching.The aim of the research is to utilise machine learning techniques to improve sustainable crop production and management techniques, thereby optimising crop production efficiency. Specifically; we will use a variety of machine learning and advanced data analytic techniques to extract new knowledge and information that were never known before. This knowledge will be used for decision-making, process production optimisation, resource planning, and more importantly it will be used to build an intelligent integrated crop model, which will underpin the advice offered by a suite of intelligent advisory tools.Salary range: €44,266 - €48,205 per annum Appointment on the above range will be dependent upon qualifications and experienceClosing date: 17:00hrs (local Irish time) on 31 July 2019.Applications must be submitted by the closing date and time specified. Any applications which are still in progress at the closing time of 17:00hrs (Local Irish Time) on the specified closing date will be cancelled automatically by the system. UCD are unable to accept late applications.Prior to application, further information (including application procedure) should be obtained from the Work at UCD website: https://www.ucd.ie/workatucd/jobs/. UCD do not require assistance from Recruitment Agencies. Any CV's submitted by Recruitment Agencies will be returned

8567| Mayo Clinic Florida, Department of Neuroscience| Post-Doctoral Research Fellow| Postdoctoral position available immediately to perform family and population-based genetic methods to identify and implicate genetic mutations in human neurodegenerative disease. Subsequent functional analysis may include molecular, biochemical, -Omics and cell-culture approaches. Current research projects are dedicated to understanding the molecular basis of Parkinson’s disease (PD), Lewy body dementia (DLB) and related movement disorders.At present, we seek a highly motivated individual to carry out postdoctoral research. The successful candidate must be creative and must have the ability to find and apply innovative bioinformatics methods to biological questions. Individuals with a Ph.D. or M.D./Ph.D. are eligible to apply. They must have experience in two or more of the following areas: molecular genetics, cell biology, genomics, computational biology/bioinformatics, and Next-generation sequencing technologies. They must have excellent verbal and written communication skills and a record of peer-reviewed publications. In the short term, the successful applicant will be encouraged to be part of a research team; in the longer term, the applicant is expected to seek and obtain independent funds. Mayo Clinic Florida (Jacksonville) is one of the leading research centers in neurodegenerative disorders in North America. Interested applicants for this position should send by e-mail a curriculum vitae, a brief statement of research interest and the names and telephone numbers of two references.

8550| UKRI Medical Research Council, Laboratory of Molecular Biology| Postdoctoral Scientist - Neurobiology - Dr Anne Bertolotti - LMB 1112| Postdoctoral ScientistStarting Salary £30,914 to £33,755 per annumMRC Laboratory of Molecular Biology, Cambridge, UKThe MRC Laboratory of Molecular Biology is a world leader in biological research, with an expanding scientific programme dedicated to understanding gene function in health and disease. It provides an unsurpassed environment for both young and established researchers. Scientists are drawn to the LMB from all over the world, creating a lively and international community for the exchange of ideas and technical innovation.We are looking to recruit a biochemist with expertise and interests in protein expression, purification, enzymology and structural or biophysical studies. You will join Dr Anne Bertolotti’s pioneering research programme, which focuses on innovative approaches to rescue cells from protein misfolding, a condition at the origin of many human diseases, including neurodegenerative diseases. One of such approaches consists in selective inhibition of phosphatases, an important discovery because phosphatases were thought to be undruggable before this work (see Tsaytler et al., 2011, Science, 332, 91-4; and Das et al., 2015, Science, 348, 239-242, Carrara, M., Sigurdardottir, A., & Bertolotti, A. (2017). Nat Struct Mol Biol, 24(9), 708–716). Krzyzosiak, A., Sigurdardottir, A. et al., A. (2018). Cell, 174(5), 1216–1228.e19.)You will join a strong inter-disciplinary team at the LMB which has broad expertise extending from biochemistry, structural, chemical, molecular and cell biology through to transgenic animals models of degenerative diseases. We also have an excellent record of innovative basic research leading to applications in medicine, a passion for science and a commitment to explore the unknown.Further information about the position may be obtained from Dr Anne Bertolotti– email: [email protected] You will be ambitious, creative and fearless. You will have a PhD molecular or cell biology due to complete doctoral studies within 6 months of applying. Relevant experience is required and this must be best attested by at least one impactful publication. Experience with mouse models is essential. An interest in signaling and/or stress responses/protein quality control is desirable. The MRC Laboratory of Molecular Biology is a research institute within UK Research and Innovation (UKRI). UKRI is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at www.ukri.org.Working for UKRI MRC provides a whole host of benefits including a defined benefit pension scheme, excellent holiday entitlement (40 ½ days including bank holidays and privilege days) and Benenden Healthcare membership. You will also have access to employee shopping/travel discounts, on site sport and social facilities, as well as salary sacrifice cycle to work schemes and childcare vouchers.To apply and access full details of the vacancy please visit our job board at https://mrc.tal.net/vx/lang-en-GB/appcentre-1/tmpwid-7c20_1d396251-2252-4867-8a5b-3b9423c960ff/candidate/postings/1253.If you are unable to apply online please contact us at [email protected] date: 1 August 2019Final appointments will be subject to a pre-employment screening.The Medical Research Council is an Equal Opportunities Employer who participates in the Disability Confident scheme.

8545| Albert Einstein College of Medicine, Genetics| Transcriptional regulators of neural development| Basic Helix-loop-Helix transcription factors are master regulators of neural cell fate determination and differentiation (Development 145: dev159426 2018). The activity of bHLH proteins is regulated by positively-acting and negatively-acting modulators that also have profound contributions to development and disease (Dev Cell 35:269-280 2015). A position is available to participate in the identification and characterization of novel regulators of bHLH gene function. The successful candidate will employ genetic, molecular genetic, and biochemical approaches to identify and characterize regulators of neurogenesis in the fruitfly Drosophila. The specific experiments may include biochemical, genetic, whole-genome sequencing and live imaging approaches.

8531| D. E. Shaw Research| Postdoctoral Fellowships in Computational Chemistry and Biology at D. E. Shaw Research| D. E. Shaw Research is seeking postdoctoral fellows of exceptional ability to join our New York–based team. This is a unique opportunity to develop and work with transformative technology in a dynamic, interdisciplinary environment. Candidates should have expertise in computational biophysics or chemistry, structural biology, drug discovery, or in a relevant area of computer science. Relevant areas of experience might include direct application of molecular dynamics or other computational methods to drug discovery, investigation of allosteric interactions or other functionally important conformational changes in biological molecules, structure prediction or design for proteins or RNA, study of protein–protein or protein–nucleic acid interactions, or study of fundamental biophysical problems, such as protein and RNA folding. Specific knowledge of any of these areas is less critical, however, than outstanding intellectual ability, unusually strong research skills, and a history of innovation and accomplishment. We are committed to fostering a stimulating, rewarding, and flexible work environment, and we offer above-market compensation to candidates of truly exceptional ability.To submit an application, please use the link provided below: http://www.deshawresearch.com/recruit/jobs/Ads/FindAPostDoc/ChemPF-AD. E. Shaw Research is an independent research group that is pursuing an ambitious, long-term strategy aimed at fundamentally transforming the process of drug discovery. We have developed a special-purpose supercomputer, ANTON®, capable of executing molecular dynamics (MD) simulations orders of magnitude faster than was previously possible. Our current projects include investigations of proteins and other biomedically relevant macromolecules as well as the development of computational chemistry methods to enable more accurate and effective MD simulations.D. E. Shaw Research is an equal opportunity employer, dedicated to the goal of building a diverse workforce. We welcome inquiries from all exceptionally well-qualified applicants, regardless of race, color, nationality, national or ethnic origin, religion or religious belief, caste, gender, gender identity, pregnancy, caregiver status, age, military service eligibility, veteran status, sexual orientation, marital or civil partner status, disability, or status in any other category protected in this regard by law in any jurisdiction in which the Firm operates.

8543| Cactus Communications| Editors - Physical Sciences and Medicine (work from home; Flexible hours)| Cactus Communications is a leading provider of scientific communication services to more than 198,000 clients across 116 countries.We engage a team of highly skilled editors who are experts in various academic fields. Cactus Communications has consistently ranked among the top 20 on the global list of the Top 100 Companies for Telecommute Jobs (Forbes.com) since 2016. We are currently looking to hire editors on a contractual work-from-home basis in the Engineering, Electronics, Computer Science Physics and Medicine. WHAT YOU NEEDA Post Doc/PhD/Masters/Bachelors degree or expertise in one or more specialized subject areas in Medicine or Physical Sciences. Excellent editing skills and attention to detail (prior editing experience would be great).WHAT YOU WILL DOEdit manuscripts such that the final text is in standard scientific English and is free of unclear or unidiomatic sentences.Adhere to job-specific guidelines and format manuscripts according to the target journal when required.Understand client and industry requirements and adapt your working approach accordingly.Meet deadlines (which are driven by client deadlines).WHY THIS IS A GREAT OPPORTUNITYYou can telecommute from anywhere.You have the flexibility to choose your own timings and work hours. Meeting deadlines and the monthly minimum volume of 60,000 words is of vital importance.Since this is a contractual arrangement, there is no mandatory time commitment. However, Editors typically tend to devote six to eight hours a day for this role.Predictable volume of work per month. The more number of words you edit, the higher you are likely to earn. Our contractors edit 60,000 to more than 120,000 words on a monthly basis.You will develop an understanding of the finer points of editing.You will have access to articles on the latest industry trends and publication and writing tips on our learning and discussion platform.You will gain an inside view into research carried out worldwide.You can provide similar services to other entities. However, these services should not adversely affect the interests of CACTUS and confidentiality should be maintained.You have the potential to earn above USD 3000 per month.APPLY NOW!Please access this link: https://tinyurl.com/y6q635s7Do mention ‘Find A Post Doc’.

8573| Laval University, Québec City, Canada, Department of Medicine| Fully financed postdoc position in genetic epidemiology| Cardiometabolic diseases such as cardiovascular diseases, type 2 diabetes and non-alcoholic fatty liver disease represent an important financial burden in developed and developing countries. New disease biomarkers and therapeutic targets need to be identified and validated to improve the health of individuals at high risk for chronic cardiometabolic disease. The objective of this project is to identify and validate new genes and therapeutic targets for a broad range of cardiometabolic diseases and healthspan using multi-omic and big data approaches (genomics, transcriptomics [RNA sequencing] and proteomics). For that purpose, will use combine tissue and blood samples from the Biobank of the Quebec Heart and Lung Institute as well as publicly available datasets of large-scale human genetics studies. This project will identify and validate novel biological and psychosocial determinants of cardiometabolic diseases, human lifespan and healthspan and identify new therapeutic targets that could one day be used to prolong life and promote healthy living into old age. The interaction between genetic variants and lifestyle-related factors will also be investigated.Requirements for applicants:- Have a Ph.D. in a field related to biomedical sciences;- Ability to speak and write in English;- Be interested in human genetics and big data approaches;- Be interested in working with bioinformatics tools;- Have authored or co-authored peer-reviewed scientific manuscripts Send your CV to:Benoit Arsenault, Ph.D.Centre de recherche de l’Institut universitaire de cardiologie et de pneumologie de Québec Department of Medicine, Faculty of Medicine, Université Laval, Québec, CanadaY-3106, Pavillon Marguerite D'Youville,2725 chemin Ste-Foy, Québec (QC) Canada, G1V 4G5T: 418-656-8711 ext. 3498Email: [email protected] : 418 656-8711 p.3498Twitter : @ArsenaultBenoit

8555| University College London, MRC Laboratory for Molecular Cell Biology| Post-­doctoral Research Fellow -­ single cell analysis of decision-­ making in development| We are pleased to announce a call for applications for a post-­doctoral researcherposition in the lab of Professor Jonathan Chubb in the MRC Laboratory for Molecular Cell Biology (https://www.ucl.ac.uk/lmcb/users/jonathan-chubb). To understand how cells decide their fates, during development and reprogramming, the lab develops and implements powerful new technologies to directly monitor gene activity in single cells (eLife e13051, Curr Biol 27:1811-­17,PNAS 115:8364-­8369). This position is an ideal platform for developing an independent research career in a rapidly expanding sector of the life sciences.Candidates are expected to be exceptional, highly motivated scientists with a strongtrack record of research in a relevant area of the life sciences. We will also consider applicants with a PhD in physics or engineering with a strong interest in biology.Work will be carried out at the MRC Laboratory for Molecular Cell Biologyhttp://www.ucl.ac.uk/LMCB/. The LMCB is a focal point for molecular, cell and tissue biology in the UK and is situated in the main UCL campus, in the heart of central London.The position is available to start from 1st November 2019 until 31st October 2021initially. The appointment will be on UCL Grade 7, with a starting salary on Grade 7 of £35,328 to £42,701 p.a. inclusive per annum. If the PhD has not yet been awarded, the appointment will be made at Research Assistant Grade 6B (salary£30,922 -­ £32,607) per annum inclusive, with payment at Grade 7 being backdated to the date of final submission of the PhD thesis.A job description, person specification and the online application form are available at http://www.ucl.ac.uk/hr/jobs. This site offers details of the application process and who to contact if you have any queries. Informal inquiries should be directed to Prof Jonathan Chubb ([email protected])

8571| University of Copenhagen, The Faculty of Health and Medical Sciences| Three Postdoc positions in mass spectrometry-based proteomics and cell signalling| Three postdoctoral stipends are available in the group of Jesper Olsen at the Novo Nordisk Foundation Center for Protein Research (CPR – www.cpr.ku.dk). The Center is part of at the Faculty of Health and Medical Sciences, University of Copenhagen, and was established to promote basic protein research and comprises a wide range of expertise and technology platforms including mass spectrometry, imaging, protein production and biophysical characterization. The three 3-year post-doctoral positions are part of two ongoing H2020 grants, EPIC-XS and HighResCells, to commence 1 November 2019 or soon after. The Postdoc research projects aim at developing and applying high-resolution quadrupole orbitrap based data-independent acquisition (DIA) for quantitative (phospho)proteomics of perturbed cell signalling pathways. Our researchThe “Mass Spectrometry for Quantitative Proteomics” Group is headed by Prof. Dr. Jesper V. Olsen, who is also vice director of the Center. It is a highly interdisciplinary group consisting of international researchers with diverse competences in analytical chemistry, mass spectrometry, proteomics, molecular biology and bioinformatics. The major scientific focus area for the Olsen Group is quantitative, high-resolution mass spectrometry-based proteomics with specific emphasis on systems-wide analyses of dynamic post-translational modifications such as site-specific phosphorylation that regulate essentially all cellular signal transduction pathways. The Olsen Group continuously develop the entire proteomics workflow including offline peptide fractionation and enrichment methods combined with different high-resolution orbitrap tandem mass spectrometry acquisition strategies with the aim to be more robust, reproducible, and rapid. The goal of the Olsen Group is to solve questions in biology and biomedicine by analyzing cellular phospho-signaling networks following activation by extracellular stimuli or stress and link this to cellular phenotypes and diseases. The Group make use of state-of-the-art orbitrap mass spectrometry (Bekker-Jensen et al, Cell Systems 2017; Kelstrup et al, J. Proteome Res. 2018) and apply it signaling questions in cell culture models (refs. Francavilla et al, Mol Cell 2013; Batth et al, Cell Reports 2018; Emdal et al, Science Signaling 2015 and 2018) as well as in tissues (refs. Lundby et al, Science Signaling 2013; Lundby et al, Nature Methods 2014). For more information about the Olsen Group, please visit: https://www.cpr.ku.dk/research/proteomics/olsen/. Your job The Postdoc research projects aim at developing and applying tandem mass spectrometry (MS/MS) based methods to identify and quantify cellular phosphor-signaling networks as a function of stimuli and time. The development of data-independent acquisition strategies and application of such methods to study phosphoproteomes of growth factor activated cells, tissues, organs and patient material. The project will also require careful development of activities for public engagement as well as writing scientific articles, papers, reports or books, as appropriate. The candidates will also be required to attend network-wide workshop events and take active part in network-wide remote activities. Moreover, postdocs are expected to take part in supervising graduate and undergraduate students in the Olsen Group, and help teaching in PhD courses and undergraduate courses, when required. Profile We are looking for highly motivated candidates with expertise in mass spectrometry-based protein or molecular biology and kinase-driven cell signaling. We are therefore looking for strong post-doctoral researchers with the following competencies and experiences:Essential experience and skills:• You have a PhD in biotechnology, biochemistry, analytical chemistry, or related science.• Strong scientific track record demonstrated by high-quality publications about MS-based proteomics and/or cell signalling in peer reviewed international journals as first author.• The candidate should be able to conduct independent and creative research, and show good inter-personal and communication skills. • Perform independent, high-quality research and developments in mass spectrometry-based proteomics technologies and apply this to global analysis of protein digests and PTM-enriched samples.• You have prior experience in molecular and cellular biology experiments including immunoblotting, immune-affinity enrichments, sandwich ELISA assays, and cellular assays. • You are excellent in written and oral communication in English.• You have experience in research collaborations and have demonstrated enthusiasm, motivation, flexibility and confidence.Desirable experience and skills:• Experience in handling, processing and bioinformatically analyzing large-scale scientific datasets.• Experience in experimental design, and planning of complex proteomics experiments.• Experience with script programming in the languages such Perl, R, or Python is a clear advantage.• Hands-on experience with high-resolution Orbitrap mass spectrometry (Q Exactive or Lumos instrumentation).• Prior experience with EU-funded large-collaborative proteomics-focused research projects is an advantage.Place of employment The place of employment is in the Olsen Group in the Proteomics Program at Novo Nordisk Foundation Center for Protein Research, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories and state-of-the-art proteomics equipment and infrastructure.Terms of employment The employment as postdoc is a full time and fixed-term position for 3 years and starting date is 1 November 2019 or after agreement. The position is covered by the “Memorandum on Job Structure for Academic Staff at the Universities” of June 28, 2013. Questions For further information, please contact Professor, Dr. Jesper V. Olsen by e-mail: [email protected] Foreign applicants may find this link useful: www.ism.ku.dk (International Staff Mobility). Application procedure Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore your application must include the following documents/attachments – all in PDF format:1. Motivated letter of application (max. one page).2. CV incl. education, work/research experience, language skills and other skills relevant for the position.3. A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do.4. List of publications.Application deadline: 15 August 2019, 23.59 p.m. CET.

8554| Barcelona Supercomputing Center| STARS: SupercompuTing And Related applicationS Fellows Programme| The Barcelona Supercomputing Center - Centro Nacional de Supercomputación (BSC-CNS) is the leading supercomputing center in Spain. It houses MareNostrum, one of the most powerful supercomputers in Europe, and is a hosting member of the PRACE European distributed supercomputing infrastructure. The mission of BSC is to research, develop and manage information technologies in order to facilitate scientific progress. BSC combines HPC service provision and R&D into both computer and computational science (life, earth and engineering sciences) under one roof, and currently has over 600 staff from 49 countries.STARS programme aims at fostering the training of highly skilled post-doc in all fields of High Performance Computing and related applications. This initiative is part of COFUND call of the Marie Sklodowska Curie Actions within the Horizon 2020 Programme.The programme will award 20 outstanding post-doctorate researchers of all nationalities with 24-month INCOMING fellowships, providing them with all necessary tools for developing their potentials, deepening their skills and knowledge in a stimulating, international and interdisciplinary environment, and offering them intersectorial short secondments (1-3 months) with private industry or non-academic research centres (such as Lenovo, CISCO, AstraZeneca, IBERDROLA, EU JRC, AEMET, IRB and CRG in order to boost their career perspectives as successful independent researchers. Short secondments periods under the premises of these partner institutions will take place within the STARS programme. Fellows will also be strongly encouraged to participate at least once a year in an international event in their domain of research.This call will award up to 12 fellowships.

8565| CeMM| CeMM International Postdoc Program (Vienna, Austria) Pre-ERC Postdoc Program in Cellular, Molecular and Digital Medicine| The postdoc program is based at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences in Vienna, one of Europe’s leading centers for basic biomedical research – with clinical translation in mind. Selected candidates will join one of CeMM’s research groups for 3 to 6 years, addressing ambitious research questions in areas such as cancer, immunology, chemical biology, epigenetics, metabolism, and genomic medicine. Research projects will focus on medically relevant problems, including disease mechanisms, modern therapeutics and diagnostic strategies. On top, postdocs will receive extensive career development and leadership training from the entire CeMM Faculty and additional experts in a highly collaborative and supportive environment.What we offer:• An international group of highly collaborative colleagues that will help you achieve your scientific and career goals• Top-notch environment with the ideas, projects, resources, infrastructure, collaborations, and mindset for groundbreaking research• Excellent track record of past postdocs who have become internationally successful principal investigators, professors, entrepreneurs• Strong focus on disease biology and translational research: cancer, metabolic disorders, inflammation/infection, drug discovery• Interdisciplinary projects connecting biology with medicine, experiments with computation, and discovery with translation• Unique opportunity to engage close interactions with physicians and clinical researchers at the Medical University of Vienna in one of Europe’s largest medical campuses• Opportunities to collaborate with industry (biotech/pharma) and to get involved in academic start-up/spin-off companies• Training program in project management, scientific writing, visual communication, entrepreneurship, leadership and data science• Special training for writing successful ERC Starting Grants as a “ticket” to an outstanding academic career in Europe• Mentoring Program within EU-LIFE (https://www.eu-life.eu), an alliance of 13 top research centers in life sciences to support and strengthen European research excellence• Being part of a thriving academic and social community in Vienna, one the cities with the best quality-of-life in the world• A competitive postdoc salary according to the Austrian Science Fund (https://www.fwf.ac.at), which amounts to an annual gross salary slightly above EUR 50,000. The CeMM employment contract includes full insurance (health, accident, pension) and a one-off payment for moving• CeMM’s HR department and administrative team offers support with relocation, visa applications, onboarding, family support, etc.Whom we are looking for:• Candidates who want to pursue innovative biomedical research and substantially advance their scientific career• Open to both PhD (natural sciences) and MD (medical sciences) holders• From a variety of academic backgrounds: molecular biology, biomedical research, bioinformatics, biochemistry, bioengineering, etc.• With the motivation, skills, experiences, and initial achievements (subject to academic age) to qualify for a competitive postdoc program• Required are scientific quality and originality, as well as a collaborative and interdisciplinary mindsetPotential projects:• Host pathogen interactions (Bergthaler Lab); Mechanistic investigations of the dynamic evolution of chronic viruses• Immunometabolism (Bergthaler Lab); Metabolic inter-organ communication during inflammation and infection• Cancer immune modeling (Bock Lab); Single-cell analysis of immune deregulation in (humanized) mouse models of cancer• Human synthetic biology (Bock Lab); Developing new cell-based therapies (CAR T etc.) using combinatorial bioengineering and machine learning / artificial intelligence• Precision pediatric oncology (Boztug Lab); Integrating multi-omics profiling with ex vivo image-based drug sensitivity testing for personalized therapies• Organoid-omics (Boztug Lab); Profiling patient organoids from inherited rare diseases and pediatric cancer patients for precision medicine• Chemical epigenetics (Kubicek Lab); Developing novel chemical probes targeting cancers with mutations in chromatin modifiers• Nuclear metabolism (Kubicek Lab); Studying the role of chromatin-bound metabolic enzymes in leukemias• Cellular transporters (Superti-Furga Lab); Targeting cellular transporters to modulate disease• Systems biology (Superti-Furga Lab); Network-based systems-level analysis of the human transportome• Cancer biology (Villunger Lab); Interrogating the PIDDosome in ploidy control for tumor suppression• Polyploidization in health and disease (Villunger Lab); The role of polyploidy in heart development and regeneration• Targeted protein degradation (Winter Lab); Medicinal chemistry strategies to modulate the proteolytic machinery for cancer therapy• We are open to other ideas that fit into the broader scope and mission of the CeMM Research Center for Molecular MedicineThe Institute (http://www.cemm.at/) CeMM is an international research institute of the Austrian Academy of Sciences and a founding member of EU-LIFE. The mission of CeMM is to achieve maximum scientific innovation in molecular medicine to improve healthcare. It has an outstanding track record of top-notch science (last few years: >10 papers in Nature/Cell/Science/NEJM, >25 papers in Nature/Cell sister journals) and medical translation. At CeMM, an international and creative team of scientists and medical doctors pursues free-minded basic life science research in a large and vibrant hospital environment of outstanding medical tradition and practice. CeMM’s research is based on post-genomic technologies and focuses on societally important diseases, such as immune disorders and infections, cancer and metabolic disorders. We operate in a unique mode of super-cooperation, connecting biology with medicine, experiments with computation, discovery with translation, and science with society and the arts. The goal of CeMM is to pioneer the science that nurtures the precise, personalized, predictive and preventive medicine of the future, and to train a modern blend of biomedical scientists to make great contributions. Please apply online: https://cemm.jobbase.io/job/x2ogrjd9 with 1) a cover letter including a short summary of research interests, 2) curriculum vitae (CV), 3) academic transcripts, and 4) contact details of three referees. Applications received by 31 August 2019 will be considered. The preferred starting date is January 2020 or earlier.