The Haigh lab recently located to the Research Institute in Oncology and Hematology (RIOH) that is part of CancerCare Manitoba and the University of Manitoba. We are presently seeking junior and/or senior postdoctoral researchers or research associates interested in joining our lab. Our group is presently interested in further investigating the role that ZEB and SNAI family of transcription factors as well as VEGF signalling play in normal hematopoiesis and leukemia transformation (see some representative publications below). We expect that interested candidates would be willing and able to apply for their own local/national and international funding after initial 3 years of support and have competitive CVs. The following skill set would be important (but not essential) for successfully contributing to our lab’s primary research efforts:
1) Experience in working with mouse and/or human models of hematopoiesis and leukemic transformation or other cancer models.
2) Experience using multicolour FACS and cytometric analysis of mouse/human hematopoietic system.
3) Previous experience working with large datasets generated by RNA/ChIPseq or single cell sequencing approaches.
4) Experience working with CRISPR/Cas9 gene editing systems and retro/lentiviral delivery of gRNA and shRNA cargoes to hematopoietic progenitors/cell lines.
5) Strong background in molecular biology and/or protein biochemistry.
6) Previous experience in working with human ES/iPS cells.
Sample Haigh Lab Publications:
1) Goossens et al., Blood. 2017 129(8):981-990.
2) Li et al., Blood. 2017 129(4):460-472.
3) Goossens et al., Nature Communications. 2015 6:5794.
4) Haenebalcke et al., Cell Reports. 2013 3(2):335-41.
5) Maes et al., EMBO J. 2010 29(2):424-41.
6) Drogat et al., Blood. 2010 116(12):2141-2151.
The population of Winnipeg, Manitoba, Canada is about 700,000. The city has excellent facilities for most cultural, sporting, and recreational activities. Winnipeg is home to the Winnipeg Symphony Orchestra, Manitoba Opera, Royal Winnipeg Ballet, Manitoba Theatre Centre, and Winnipeg Art Gallery. Professional sports teams include Blue Bombers football, Winnipeg Jets hockey, and Valour Football Club, Winnipeg’s professional soccer club. Outdoor recreational activities are found throughout the province of Manitoba in all seasons. Winnipeg is also highly affordable compared with other major Canadian cities.
The University of Manitoba is strongly committed to equity and diversity within its community and especially welcomes applications from women, racialized persons, Indigenous Peoples, persons with disabilities, persons of all sexual orientations and genders, and others who may contribute to the further diversification of ideas. If you require accommodation supports during the recruitment process, please contact U of M’s Equity, Diversity and Inclusion Facilitator, Valerie Williams at
[email protected] or 204-474-8371. All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.
Application materials, including letters of reference, will be handled in accordance with the protection of privacy provision of The Freedom of Information and Protection of Privacy (Manitoba). Please note that curriculum vitae may be provided to participating members of the search process.
Initial CIHR project based funding is for a three-year period and salary level will be commensurate with qualifications and experience. Initial start date is negotiable, and review of applicants will begin in July, 2019 and will continue until position is filled.
Interested Candidates should send their CVs and the names and contact information of three references to the following e-mail address:
Associate Professor Jody Jonathan Haigh
Department of Pharmacology and Therapeutics
Rady Faculty of Health Sciences
University of Manitoba
Senior Scientist
Research Institute in Oncology and Hematology (RIOH)
CancerCare Manitoba, ON5029
E-mail:
[email protected]
