• European Molecular Biology Laboratory (Heidelberg) Featured Post Docs
  • CeMM Featured Post Docs

Research Fellow in Biomedical Molecular Dynamics for Drug Discovery

  • Application Deadline
    29 June 2019
    (application date has expired)
  • Job Salary
    £35,328 to £42,701 Inclusive of London Allowance
  • Website
  • Contact Name
    Prof Peter Coveney

Applications are invited for a Research Fellow to work with Professor Peter Coveney in the Department of Chemistry at University College London. The successful candidate will join a very active inter-disciplinary group in the Centre for Computational Science, working on projects in fields ranging from condensed matter physics and chemistry to life sciences and medicine.

This post will involve the development of molecular models to support computer-based drug discovery and to investigate the biophysical and biochemical origins of drug resistance in pathologies such as HIV, cancer, and antimicrobial resistance, using established molecular dynamics codes such as NAMD and OpenMM. A key element of the approach is the development and use of automated workflows to assist in the rapid, accurate, precise and reproducible determination of binding affinities running on a range of ultra-high-end supercomputers, including Summit, number one in the Top500 list of supercomputers worldwide.

The postholder will work closely with a large number of international projects across Europe and USA, and with collaborating industrial (pharma/biotech) and public sector partners who have an interest in exploiting our approaches in industry and healthcare.

The post is funded by the European Commission and is available for a period of 24 months initially, to start as soon as possible.

A PhD degree (or near to being awarded a PhD) in biomolecular dynamics as used to perform free energy and related calculations of ligand-protein binding is essential, as is extensive experience with high performance computing. The postholder must also have experience of using common molecular dynamics packages including at least two of NAMD, AMBER, GROMACS and OpenMM. An excellent and consistent publication track record is also essential.

Please note, appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at Research Assistant Grade 6B (salary £30,922 to £32,607 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis.

For further details about the vacancy and how to apply online please go to https://www.ucl.ac.uk/human-resources/working-ucl/jobs-ucl and search on Reference Number 1808740.

Informal enquiries should be addressed to Prof Peter Coveney ( [email protected] ). Any queries on the application process can be directed to Judith James – [email protected] .

Closing Date: 29/6/2019

Latest time for the submission of applications: 23:59.

Interview Date: TBC

We particularly welcome female applicants and those from an ethnic minority, as they are under-represented within UCL at this level.

Our department holds an Athena SWAN Bronze award, in recognition of our commitment to advancing gender equality.To apply click here https://atsv7.wcn.co.uk/saf/login.cgi?SID=ZXh0ZXJuYWw9MjQ2MzQ3Jm93bmVyPTUwNDExNzgmamNvZGU9MTgwODc0MCZvd25lcnR5cGU9ZmFpcg==

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