Project Description
The Project:
Electrosynthesis is a powerful tool in organic chemistry that circumvents the use of expensive and toxic reagents for the generation of reactive intermediates. During electrosynthesis, molecules are activated under mild and green conditions directly at the surface of an electrode. Even though a plethora of transformations have been developed and many of them were successfully used in several industrial processes the potential of preparative organic electrochemistry remains largely underestimated. However, the growing impetus to look for greener and cheaper alternatives to classic synthetic methodologies prompted us to investigate further new electrochemical reactions.
We have recently developed two novel electrochemical methodologies that allow generating organic and organometallic radicals under mild, green, economical and safe conditions. We have successfully applied those methodologies to the preparation of new types of anticancer drugs.
We are now looking for a highly motivated Post-doctoral researcher to join our team and explore further the synthetic potential of these radicals.
The candidate:
The project would be suitable for a PhD holder with a strong background in synthetic chemistry and interest in medicinal chemistry and electrochemistry.
The project will be supervised by Dr Kevin Lam (
http://www.lamresearchgroup.com,
http://www.gre.ac.uk/engsci/study/pharchemenv/staff/kevin-lam)
Research Environment:
The successful candidate will join a highly active research group in newly refurbished synthesis laboratories. The Department is extremely well equipped with analytical equipment (including a glovebox, several Electrasyns 2.0, high-speed potentiostats, 4xNMR spectrometers, large mass spectrometry suite, etc.)
Duration: 1 year, Full-Time. Opportunity to extend for a further 12 months
For informal enquiries about the project, please contact Dr Kevin Lam : k.lam ’ at ’ greenwich.ac.uk
References
“Electrochemical synthesis of phthalides via anodic activation of aromatic carboxylic acids” Hayrapetyan D., Shkepu V., Seilkhanov O. T., Zhanabil, Z., Lam K., Chem. Commun., 2017, 53, 8451
Please send your resumé and a copy of your PhD thesis to k.lam 'at' greenwich.ac .uk
