• Job-ID: V000012102
• Field of application: Klinik für Kardiologie, Angiologie und Pneumologie
• Location: Heidelberg
• Start date: As soon as possible
• Job Category: Science and teaching
• Working hours: Part time (65 %)
• Limitation: Temporary (13 months, deferment / extension is sought)
• Contract: TV-L
PhD student position (m/f/d) wanted for the next possible date at the Department of Internal Medicine III, Cardiology, Angiology and Pneumology for the Molecular cardiology lab.
The University Hospital Heidelberg is one of the major healthcare centers in Germany. Our objective is the development of innovative diagnostics and therapies as well as their quick implementation for the patient. With about 14,000 employees in more than 50 specialized clinical departments with almost 2,500 beds, about 80,000 patients in part-time and full-time inpatient treatment as well as 1,000,000 patients in ambulant treatment are medicated each year.
Your tasks
Project: Novel molecular mechanisms in the pathogenesis of cardiomyopathy and heart failure
Our Molecular Cardiology lab is inviting applications for a PhD position to investigate the role of novel molecules and pathways in the pathogenesis of cardiomyopathy and heart failure. Our broader translational aim is to explore these molecules as potential targets for therapy which will then be tested in vivo, including utilization of cardiac gene transfer (AAV-based) and small molecule screens. As part of the newly formed CRC 1550 - Molecular Circuits of Heart Disease, we have established collaborations with multiple established PIs within the Heidelberg and Mannheim experimental and clinical cardiovascular communities. As such, successful candidates will have access to state-of-the-art facilities and equipment and the opportunity to thrive in a highly collaborative scientific environment.
For more information about our research and methodology please refer to some key publications (eg. JACC Basic Transl Sci 2021 Mar 17;6(4):365-380. doi: 10.1016/j.jacbts.2021.01.001; Commun Biol. 2020 Oct 9;3(1):562. doi: 10.1038/s42003-020-01289-2; Cardiovasc Res. 2021 Nov 1;117(12):2459-2473. doi: 10.1093/cvr/cvab012; Nat Commun. 2016 Apr 28;7:11317. doi: 10.1315/11317; Circ Res 2012 Dec 7;111(12):1504-16. doi: 10.1161/CIRCRESAHA.112.271007)
Your profile
• Master's / Doctoral degree in a related field such as biology, biochemistry, life sciences
• Previous experience in molecular biology, biochemistry, -OMICS, and/or genetically modified anima l models of cardiac disease will be viewed favourably
• Basic knowledge on bioinformatics viewed as a plus
• Ability and desire to work effectively in a team
• Self-motivated and creative thinker
We offer
In our molecular cardiology lab within a modern research building (“Analysezentrum III”, University Hospital Heidelberg) we offer a dynamic and highly interactive and cross-disciplinary research environment. All OMICs experiments will be analyzed in cooperation with excellent groups on campus (eg. Prof. Saez-Rodriguez) which offers additional learning opportunities). PhD students will join the Heidelberg Biosciences International Graduate School (HBIGS) and will also take part in a specialized cardiovascular curriculum. As our group is part of the DZHK (“Deutsches Zentrum für Herz-Kreislaufforschung”) you'll have access to additional education and mentoring programmes as well as specific young investigator funding opportunities.
• Collectively agreed remuneration, attractive company pension scheme (VBL)
• 30 days vacation
• Sustainable travel: job ticket
• Family-friendly working environment: cooperative arrangements for childcare, subsidy for child vacation care, advice for employees with relatives in need of care
• Wide range of health, prevention and sports offers
Contact & application
For further information please contact Mr. Rangrez via e-mail.
Please send a motivation letter outlining your research background and interests, as well as a CV and contact information for previous mentors, direct online.
Klinik für Kardiologie, Angiologie und Pneumologie
Ashraf Yusuf Rangrez
Im Neuenheimer Feld 410
69120 Heidelberg
[email protected]Please note that the UKHD is subject to the provisions of the Infection Protection Act. Therefore, valid proof of measles immunity is required for all persons employed at the UKHD.
We stand for equal opportunities. Severely disabled persons are given priority in the case of equal suitability. The University Hospital aims to generally increase the proportion of women in all areas and positions in which women are underrepresented. Qualified women are therefore particularly encouraged to apply. Full-time positions are generally divisible, unless there are official or legal reasons to the contrary.
