Senior Research Associate

    The Medical Research Council Toxicology Unit is an internationally renowned institution focused on the delivery of field-changing mechanistic insights into toxicology and disease.

    We are offering an exciting opportunity for an experienced researcher to work on a Cancer Research UK-funded multidisciplinary Programme Award within the group of Dr Marion MacFarlane, to carry out research into the basic biology underpinning asbestos-induced disease progression and maintenance in order to identify new pathways to improve immunotherapy for mesothelioma.

    The successful candidate will join a multidisciplinary team using cutting-edge ex vivo tumour explant models (doi: 10.1038/s41416-019-0672-6) and, in collaboration with Prof. Daniel Murphy, genetically engineered in vivo models (doi:10.1101/2020.06.16.154815).

    The project will suit someone with strong skills in analysing evolving phenotypes in tumour and inflammatory/immune microenvironments for improved immunotherapy in pre-clinical models of disease that retain their microenvironment and experience in complex data integration across multi-omic platforms.

    You will have at least three years postdoctoral research experience and demonstrate the ability to work independently to develop research objectives. An expert knowledge and in-depth practical experience in the analysis of tumour and inflammatory/immune microenvironments is essential.

    Fixed-term: The funds for this post are available for 5 years in the first instance.

    Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

    If you have any queries regarding the application process, please contact [email protected]

    Further information on the Toxicology Unit can be found at (

    Informal enquiries are welcomed and should be directed to: Marion MacFarlane [email protected]

    Please quote reference PU35762 on your application and in any correspondence about this vacancy.

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