The UCL Cancer Institute is the hub for cancer research at University College London, one of the World's leading universities. The Institute draws together over 400 talented scientists who are working together to translate research discoveries into developing kinder, more effective therapies for cancer patients.
About the role
The research project will focus on understanding the molecular mechanisms that underlie glioblastoma recurrence – an aggressive and incurable cancer of the brain – focusing on the role of tumour dormancy and how it is controlled by the microenvironment. The project will leverage state of the art mouse models developed in the laboratory to define the biology of GBM dormancy using functional fluorescent reporters of label retention. A combination of cell and molecular biology, advanced imaging, transcriptomic and multiplex immunohistochemistry will be used. The post holder will be expected to work i n a focussed and organised manner to produce independent and original research within these research areas, deliver the scientific aims of the project and aid in the submission of publications to refereed journals. They will also help with supervising students and contribute to the smooth running of the research groups. The post is initially funded for 2 years with a possibility of extension.
Applicants must have a PhD in relevant subject area (eg biology, neuroscience, biomedicine). Appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at research assistant Grade 6B (salary £34,502 - £36,348 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis. Successful candidates must have a keen interest in brain cancer and demonstrable hands-on experience in stem cell isolation and culture, advanced molecular biology and in vivo techniques. Excellent organizational and communication skills are essential. Basic knowledge of bioinformatics and knowledge of glioma are desirable but not essential.
What we offer
As well as the exciting opportunities this role presents we also offer some great benefits some of which are below:
41 Days holiday (including 27 days annual leave 8 bank holiday and 6 closure days)
Defined benefit career average revalued earnings pension scheme (CARE)
Cycle to work scheme and season ticket loan On-Site nursery
Enhanced maternity, paternity and adoption pay Employee assistance programme: Staff Support Service Discounted medical insurance
Our commitment to Equality, Diversity and Inclusion
As London’s Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world’s talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong. We therefore particularly encourage applications from candidates who are likely to be underrepresented in UCL’s workforce. These include people from Black, Asian and ethnic minority backgrounds; disabled people; LGBTQI+ people; and for our Grade 9 and 10 roles, women. You can read more about our commitment to Equality, Diversity and Inclusion here : https://www.ucl.ac.uk/equality-diversity-inclusion/