Postdoctoral Researcher in Leukaemic Stem Cell Biology (ref. PD/22/12)



    Created in 2005 by the Generalitat de Catalunya (Government of Catalonia) and the University of Barcelona, IRB Barcelona is a Severo Ochoa Centre of Excellence—a seal that was awarded in 2011.

    The institute is devoted to conducting research of excellence in biomedicine and to transferring results to clinical practice, thus improving people’s quality of life, while simultaneously promoting the training of outstanding researchers, technology transfer, and public communication of science. Its 28 laboratories and seven core facilities address basic questions in biology and are orientated to diseases such as cancer, metastasis, Alzheimer’s, diabetes, and rare conditions.

    IRB Barcelona is an international centre that hosts 450 members and 35 nationalities. It is located in the Barcelona Science Park. IRB Barcelona forms part of the Barcelona Institute of Science and Technology (BIST) and the “Xarxa de Centres de Recerca de Catalunya” (CERCA).

    IRB Barcelona seeks a motivated Postdoctoral researcher for the Quantitative Stem Cell Dynamics Lab, led by Dr. Alejo Rodriguez-Fraticelli (www.fraticellilab.com).

    The lab focuses on implementing cutting-edge single-cell technologies to discover new druggable susceptibilities in leukaemia and other blood malignancies. The goal is to identify new targets to prevent drug-resistance and relapse in these terrible diseases.

    We are looking for a wet lab candidate with a strong background in cancer biology, epigenetic
    analysis and/or stem cell research. Knowledge of single-cell sequencing, clonal analysis,
    biostatistics, and/or genomics will be appreciated but is not required for this position and the candidates will be trained in all appropriate skills for this project.

    The position for this Postdoctoral researcher will be funded through the Cris Cancer Excellence
    Program awarded to the lab, with the potential to extend this contract up to 5 years. This level of
    support makes this an excellent opportunity for candidates looking to transition to an independent research-focused position.

    Duties:

    - Lead a single-cell cancer cell discovery project in the lab
    - Co-lead other projects in collaboration with PhD students and Postdocs
    - Engage in teaching and training undergrad and graduate students
    - Participate and present in group meetings and scientific discussions
    - Write manuscripts together with other researchers
    - Engage in career development activities, outreach and soft-skill training

    Experience, Knowledge, Skills & Selection Criteria:

    Must Have – Required
    - PhD in Developmental Biology, Immunology, Cancer Biology, Systems Biology, Biophysics,
    Quantitative Biology, or equivalent
    - Fluency in English

    Desirable
    - Experience in animal models of cancer
    - Experience in methods for single-cell sequencing
    - Experience in methods of chromatin accessibility and immunoprecipitation
    - Experience in international teams
    - Excellent communication skills

    Working Conditions & Entitlements:

    - Working conditions: Employed in compliance with Spanish legislation and regulations under a
    full-time contract. Employees receive the benefits of the Spanish Social Security system covering sickness, maternity/paternity leaves and injuries at work.
    - Estimated annual gross salary: Salary commensurate with experience and qualifications
    - International Environment: The opportunity to join a prestigious, diverse and inclusive
    international research institution and to become a member of the Quantitative Stem Cell
    Dynamics lab.
    - Benefits: Continuous training in a high-quality environment with unique professional career
    opportunities.


    Application and Selection Process:

    Applications for the above opening should include a full CV and Motivation Letter and should apply on https://recruitment.irbbarcelona.org/ Reference: PD/22/12

    Selection process:
    - Pre-selection: Will be based on CV, motivation letter and experience.
    - Interviews: Short-listed candidates will be interviewed.
    - Job offer: Will be sent to the successful candidate after the interview.


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