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Postdoctoral Training Fellow - Patient Derived Models team (Prof Cathrin Brisken) (ID296)



Duration of Contract: Fixed Term for 3 years
Hours per week: 35 hours per week (Full Time)
Closing Date: Sunday 10th July 2022

Research Lead: Professor Cathrin Brisken

A Postdoctoral Training Fellow position is available to advance novel PDX models for preclinical studies, translational projects, and co-clinical trials. The successful candidate will develop a pharmacological workflow, predictive biomarker discovery and contribute to generating pre-clinical information that can inform the design of clinical trials. We are seeking a highly motivated candidate who enjoys working in a multidisciplinary environment as part of a team.

Key Requirements

The successful candidate must possess a PhD in pharmacology, biochemistry, biology, or other associated subjects and have a strong track record in biomedical research. Experience in pharmacokinetics and dynamics, mass spectrometry, molecular biology, statistics, and in working with in vivo cancer models is highly desirable.

The ICR has a workforce agreement stating that Postdoctoral Training Fellows can only be employed for up to 7 years as PDTF at the ICR, providing total postdoctoral experience (including previous employment at this level elsewhere) does not exceed 10 years

Department/Directorate Information:

The Patient Derived Models Team within the Breast Cancer Now Research Centre derives and facilitates the use of in vivo patient-derived xenograft (PDX) models of breast cancer, as well as in vitro 3D organoid models (patient-derived organoids; PDO and PDX-derived organoids PDXO). Our Patient derived xenograft (PDX) area of research is lead by Prof. Cathrin Brisken focusing on developing PDX models for preclinical studies and personalised medicine.

The Breast Cancer Now Research Centre is the first centre in the UK entirely devoted to breast cancer research, with the goal to advance research into the causes, diagnosis, and treatment of breast cancer. The Centre is directed by Professor Andrew Tutt and is located in state-of-the-art laboratory space, with excellent core facilities and funding.
We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Dr Rebecca Marlow via email at
Please submit application on our site, job ref 296


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