Postdoctoral Research Assistant: Lymph node stromal Immunology (QMUL24344)

Applications are invited for a 14 moths Postdoctoral Research Associate position to join the laboratory of Lalit Kumar Dubey within the Centre for Microvascular Research at William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London (SMD-QMUL). The project will be focusing on lymph node fibroblastic reticular cells and B cell interaction (Dubey LK 2016, Cell Reports) which govern the lymphatic function and lymphangiogenesis in type-2 settings (Dubey LK, 2017 Nat Comm; Dubey LK, 2019, Cell Report). We will be using vaccination models/helminths as model organism to address the stimulating questions related to stromal-lymphocytes cross talk. The postdoctoral fellow will have an opportunity to learn 2-photon microscopy, deep tissue imaging along with novel mice models recently established to identify novel mechanisms that stromal cells employ to regulate B cells/T cells and macrophages function towards inflammation induced lymphangiogenesis. Candidate will gain research experience in the areas of stromal biology and mucosal immunology and will have an opportunity to work with the other existing groups in SMD- QMUL and require occasional travel to UK and European institutions. The research findings will be published in high impact journals, along with a definite opportunity to present his/her work at national and international meetings.

The position requires a Ph.D. in the biological sciences or related discipline. Research laboratory experience with in-vivo mouse models with strong background in conducting experiments using Cre-Lox mouse system is a must. The successful candidate should have a PhD (or be close to completion) are encouraged to apply. An excellent interpersonal, and communication skills (both verbal and written) is essential. Previous experience with multiplex flow cytometry, histological techniques, quantitative imaging, stroma isolation along with a proven track record of published research would be an advantage. Candidates with prior experience in helminth infections models, host-pathogen interaction, B cell biology, lymph node stromal analysis are highly encouraged to apply.