Postdoctoral Scientist –Stem Cell Biology
• Job Ref: PI/10/42
• 3 year fixed-term contract
A three year position is available in the laboratory of Dr Georges Lacaud to study the role of the transcription factor AML1/Runx1 in early haematopoietic development and how alterations of its function leads to leukaemogenesis. AML1/Runx1 is a frequent target of gene rearrangements and mutations in human Acute Myelogenous Leukemia (AML) and Acute Lymphoblastic Leukemia (ALL) and also a master regulator of haematopoietic stem cells development. The in vitro differentiation system based on mouse Embryonic Stem (ES) cells and in vivo approaches will be used. Selected references: Lancrin et al., (2009) Nature. Sroczynska et al.,(2009) Blood.
The successful applicant should have a PhD in cellular biology or molecular biology. A background in haematopoiesis, immunology, leukaemogenesis or developmental biology is desirable but not required.
Informal enquiries should be directed to Dr Georges Lacaud
[email protected]The Paterson Institute is a leading cancer centre of excellence core-funded by Cancer Research UK and is an Institute of The University of Manchester. Salary in the range of £25,500 - £38,000 dependent upon qualifications and experience.
To apply for this position please visit our website:
www.paterson.man.ac.ukFor applicants who are unable to download this information from our website, please contact HR department on 0161 446 3231, email:
[email protected] to have this information sent by post.
Closing date: 22nd January 2011.
