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Postdoc & PhD Jobs

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Latest Postdoctoral Jobs
1004832| Applitracker| Study Biostatistician- pharma- Cambridge area| We are currently recruiting for a Study Statistician role with an international pharmaceutical company. The position is full-time office-based in the Cambridge area.

You will work as a member of a large biometrics team responsible for the design and implementation of regional statistical studies and programming. Your responsibilities will be broad including statistical design, advice on methodologies, protocol development, quality control of statistical analysis, and publication support.

Since you will work on clinical and observational studies in a global pharma setting, previous experience is essential. You hold MS or PhD in Statistics and have at least 2 years of experience in clinical studies.

Please contact Ivelina Georgieva from NonStop Pharma Recruitment for more information via 0044 (0) or
1004891| Allergan| Principal Scientist - PKDD, in vitro model| Allergan is seeking a motivated and technically skilled scientist with strong in vitro experimental model development expertise in dermal and/or ocular scientific areas. This incumbent will lead a group to conceive, design and develop innovative in vitro experimental models to support pharmacokinetics and drug distribution activities such as dermal and ocular penetration and formulation screening for discovery programs and development projects. Primary responsibilities include in vitro model development, design and execution of in vitro experiments, sample bioanalysis, data interpretation and presentation. Candidate will be able to work independently and collaboratively with colleagues across multiple disciplines. In addition, the successful candidate will represent PKDD department to participate in discovery and development teams.

Maintain current knowledge of in vitro experimental models in ocular and dermal therapeutic areas through literature review, interaction within scientific associations and scientific meetings and professional publications.

Identify issues and provide scientifically-valid solutions to support drug discovery and development. Analyze study results, interpret data, contribute to discussions, and communicate significant events and issues to departmental and project teams. May involve preparation of quality reports and protocols for submission to regulatory and corporate agencies.



PhD +6 years or MS years or BS years specific experience with educational background in Biochemistry, Pharmaceutical Sciences
Experience for mentoring developing scientists and technical staff and working in a fast-paced team environment


Essential Skills and Abilities:

Require strong scientific skills in in vitro experimental model development in ocular and dermal areas. Creative problem-solving skill and a can-do approach.
Excellent interpersonal skills. Effective written and verbal communication skills;
Ability to multi-task and focus on priorities. Ability to find out project team requirements and report work progress to supervisor, project team members and internal departments.
Good computer skills and ability to apply Word, Excel, PowerPoint and LIMS to facilitate data analysis, data management and reporting.
5474| King Abdullah University of Science and Technology| Post-Doctoral Fellow in Benthic Ecology| KAUST (King Abdullah University of Science and Technology)

Post-Doctoral Fellow in Benthic Ecology
Competitive Tax-free Salary

The Saudi Aramco Environmental Research Center at KAUST (SAMERCK) is seeking a post-doctoral researcher in the area of benthic ecology. Much of our work at SAMERCK is driven by the need to quantify and forecast responses to environmental change. As part of the ecological component of this new Center, overall studies aim to understand the major processes driving the structure and function of coastal systems, in particular how natural and human disturbances influence the biodiversity patterns and biological production.  

We seek applicants to participate in ongoing research about the direct and indirect effects of multiple pressures on diversity and functioning of coastal benthic communities along the Saudi Arabian Red Sea coast. The successful candidate should have expertise in areas such as: (1) the link between biodiversity and ecosystem functioning; (2) the relationships between environmental parameters and variability in soft-sediment assemblages (diversity and structure); (3) the use of multiple ecological indicators to assess environmental quality of benthic habitats; (4) statistical analysis and interpretation of community data (biodiversity, structure and trophic relationships), and/or predictive modelling tools to better understand the distribution of species/assemblages. Collaborations amongst SAMERCK research fields (oceanography, GIS spatial analysis) will be strongly supported.

Qualifications/Competencies
• PhD in Marine (Benthic) Ecology (or other related field) and preferably postdoc experience(s);
• Proven publication record in the field of marine benthic ecology with solid knowledge in macrobenthic species taxonomy;
• Documented experience of extensive ecological field surveys;
• Competency in applying and interpreting statistical analyses;
• Fluent in English, both spoken and written;
• Excellent written and verbal communication skills;
• Ability to work in multidisciplinary teams;
• Ability to produce high quality deliverables on time and to work in a multi-tasking environment;
• Good organizational skills and a strong ability to accomplish tasks independently.
• The successful candidate should be able to identify the most accurate indicators for the assessment of the ecological state of Red Sea benthic habitats, as well as to propose the thresholds to be used in future monitoring.

Main tasks:
• Conduct laboratory and field work;
• Collect and process biological and environmental samples;
• Manage the laboratory facilities (order supplies and maintain equipment);
• Conduct data analysis and contribute to the writing of reports, manuscripts and projects;
• Test several biotic indices and assess their effectiveness on the assessment of the ecological status of Saudi Arabian Red Sea.
• Identify/develop accurate indicators for the assessment of the ecological state of Red Sea benthic habitats, as well as propose the thresholds for future monitoring.

The position is for three years (renewal each year depending on performance) and includes a competitive tax-free salary and other benefits (housing, health and life insurances, etc.).

To apply, please submit a single pdf file with a cover letter, including a statement of research interests, detailed curriculum vitae, and the contacts of three references to Susana.carvalho@kaust.edu.sa






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5481| AstraZeneca| US Postdoctoral Opportunity for student, AZ Neuroscience & Tufts University| The impact of MECP2 gene-silencing on KCC2 expression function and neuronal development in Rett Syndrome

AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialization of prescription medicines, primarily for the treatment of cardiovascular, metabolic, respiratory, inflammation, autoimmune, oncology, infection and neuroscience diseases. We are science led and operate in over 100 countries and our company is comprised of many voices, views and talents united by a common mission: helping people live healthier lives, embracing diverse perspectives, and working together to create a better future.

Join the next generation of scientists at a post-doctorate level and you'll thrive in state-of-the-art laboratories, grow within an entrepreneurial and collaborative culture, one that inspires leadership and independent thought, and connect with people across our global business. Here, employees like you are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.

This is a unique opportunity to work at the interface of academia and industry as part of a recently created group of scientists working collaboratively between AstraZeneca and Tufts Neuroscience. The project will be conducted in the Department of Neuroscience at Tufts University in the heart of Boston, supervised by Professor Stephen J. Moss and in close collaboration with Joe Mather from the AstraZeneca Neuroscience IMed.

Candidate Focus and Challenge

MECP2 protein is found in all cells in the body, including the brain, acting as a transcriptional repressor and activator, depending on the context. RTT is distinguished from other neurodevelopmental disorders, especially with regards to respiratory and motor dysfunction as well as seizure susceptibility. Whilst the role of KCC2 has been established in neuronal excitability, AstraZeneca Neuroscience is seeking a post-doctoral candidate who is interested in characterizing how inactivation of MECP2 affects KCC2 function and its impact on synaptic development in Rett Syndrome.

A successful candidate will:

• Design and conduct research to characterize changes in protein levels and phosphorylation impact KCC2 function, synaptic development and seizure susceptibility in MECP2 mice
• Interact and collaborate with scientists across Tufts and AstraZeneca, become an active leader within the growing Tufts-AZ scientific community
• Publish scientific papers and attend conferences to communicate novel findings to the research community


Candidate Knowledge, Skills and Experience

Minimum experience

A PhD in pharmacology/neurophysiology with experience in one or more of the following areas:

• Experienced electrophysiologist, mainly in whole cell patch clamp and brain slice recordings
• Experience with cell culture, biochemistry and molecular biology techniques
• Experience in creating and using primary neuronal cultures or brain slices for electrophysiology and pharmacology experiment
• Understanding of neuronal development and synaptic maturation.
• Ability to design and carry out research independently
• Strong written and oral communication skills
• Ability to work effectively and collegially with colleagues and initiate collaboration


Preferred experience/requirements

• A strong scientific record of accomplishment as evidenced by published or accepted papers in well-recognized peer-reviewed journals, oral and/or poster presentations at scientific meetings.
• Strong passion and commitment to science, and ability to work well within a group/team environment.

Should you be selected for this impact of MECP2 gene-silencing on KCC2 expression, funct
5466| University of Manchester, The Cancer Research UK Manchester Institute| Prostate Cancer UK/Movember Funded Post-doctoral position in bioinformatics for prostate Cancer| • Prostate Cancer UK/Movember Funded Post-doctoral position in bioinformatics for prostate Cancer
• Job Ref: MI/14/30
• Richard Marais: Molecular Oncology Group and Caroline Dive: Clinical and Experimental Pharmacology
• Salary range: £28,500 – £38,000 depending on qualifications and experience.
• Three year duration

The CRUK Manchester Institute (www.cruk.manchester.ac.uk) in the UK is a centre for excellence in cancer research. We occupy state-of-the-art laboratories and provide exceptional core facilities, including next generation sequencing, mass-spectrometry, advanced imaging, bioinformatics, histology, and flow cytometry. We are core-funded by Cancer Research UK (www.cancerresearchuk.org), the world’s largest cancer organisation, are an Institute of The University of Manchester (www.manchester.ac.uk), and are juxtaposed to The Christie NHS Foundation Trust (www.christie.nhs.uk), one of the largest cancer treatment centres in Europe. These factors combine to provide an exceptional environment in which to pursue basic, translational and clinical research programmes in a vibrant and dynamic city surrounded by beautiful countryside and with excellent national and international transport links.

Together with Queen’s University Belfast, we have recently been awarded a Movember Centre of Excellence for prostate cancer research. Three positions are available for post-doctoral scientists to join the Molecular Oncology Group led by Prof Richard Marais, Director of the Institute, and in the Clinical and Experimental Pharmacology Group led by Professor Caroline Dive, Deputy Director of the Institute. Prof Marais has made important contributions to our understanding of the biology and genetics of melanoma (Cell 140: 209, 2010; Cancer Cell 15: 294, 2009 and 19, 2011: 45; Cancer Research 70: 8036, 2010, NEJM 366: 207-215, 2012; Genome Research 22: 196-207, 2012). Prof Dive’s laboratory has an international reputation for circulating biomarker research notably relating to the utility of circulating tumour cells in personalised medicine (J Clinical Oncology 29:1556, 2011, J Clinical Oncology 30: 525, 2012, J Thoracic Oncology 7, 306, 2012, J Investigative Dermatology 133: 1582 2013, Nature Reviews Clinical Oncology 15: 30 2014).

The successful candidate will join a team who will implement personalised medicine for prostate cancer. The post holder will be responsible for working with other team members to integrate genomics and proteomics data from patient samples. They will collaborate to advance the data for practical use in the personalised medicine platform and to pursue follow-up studies as appropriate. The successful candidate will hold a PhD in bioinformatics and relevant experience in cancer will be an advantage. The post holder will be jointly managed by Prof Marais and Prof Dive.

Informal enquiries can be directed to Professor Marais (richard.marais@cruk.manchester.ac.uk) or Professor Dive (caroline.dive@cruk.manchester.ac.uk)

For applicants who are unable to download this information from our website, please contact 01614463231, email: jobs@cruk.manchester.ac.uk to have this information sent by post.

The deadline for receipt of applications is 2 May 2014 and first round interviews will take place during mid-May.
1004913| Stamford Consultants AG| Senior Analyst Competitive&Strategic Intelligence (m/w)|

For our client, a global pharmaceutical company, we are looking for a strong candidate for the position as Senior Analyst Competitive & Strategic Intelligence (m/w)

Key responsibilities:

  • Providing an objective commercial viewpoint based on an in-depth understanding and analysis of commercial, clinical and scientific competitive information, and making recommendations on brand strategy that prepare the brand for a competitive marketplace
  • Liaising with all stakeholders to ensure up-to-date competitive intelligence and assumptions are shared with all appropriate teams 
  • Collaborating with brand to plan for competitor launches
  • Leading competitive threat assessments to develop rigorous team assumptions about key competitors; ensure coverage of priority markets for global marketing stakeholders
  • Managing/catalyzing/providing oversight to CI programs for Global brands; providing coverage for global markets

Ideal profile:

  • Bachelor Degree is required, MBA (Masters or PhD degree in life sciences preferred)
  • Minimum 2- 5 years of experience in competitive intelligence in the Pharma/Biotech/Life sciences industry
  • Specific previous experience in strategic consulting, strategy & planning, business development, competitive intelligence role within the pharmaceutical, biotech or related industries or pharmaceutical commercial consulting firms
  • Demonstrate the ability to converse in scientific terminology/therapy area
  • Experience in managing outside vendors and a budget is a plus
  • International travel required (30%)
5503| Manchester Metropolitan University, Faculty of Science and Engineering, School of Healthcare Science| Research Associate| Research Associate
(Full-time/ Fixed-term 2 year)
Grade 8: £32,590 - £37,756 per annum

Manchester Metropolitan University is one of the UK's largest and most popular Universities. We are the University for World Class Professionals. The School of Healthcare Science has an outstanding research profile and our academics are currently leading projects funded by the European Union, Industry and UK Research Councils. We seek a highly motivated post-doctoral scientist, with experience of medical image analysis, to play a major role in a project funded by the Biotechnology and Biological Sciences Research Council. The successful candidate will join our multi-disciplinary team to develop novel image analysis approaches which facilitate study of skeletal muscle activation patterns.

The well-equipped Healthcare Science Research Institute at Manchester Metropolitan University provides a range of techniques which can be used to study human movement from the level of individual fibres through to whole body biomechanics. The research team comprises expertise in neuromuscular physiology, computer vision and medical image analysis. The project will focus on the use of high frame rate ultrasound imaging which will be complemented by measures of muscle activation (intramuscular and surface electromyography, EMG) to provide insight into patterns of muscle activation. The successful candidate will therefore have algorithm development and signal processing skills.

In addition to the development and evaluation of image analysis algorithms, the Research Associate will have primary responsibility for day-to-day management of the project, aspects of ultrasound image and EMG data collection and dissemination of results. Applicants should have strong experience in medical image analysis and/or machine learning and of working as part of a multi-disciplinary team. Full training in skeletal muscle physiology and motor control will be provided. Applicants must be highly motivated, enthusiastic and engage in scholarly activities conducive to a long-term successful academic career that will support and enhance the research culture within the department.

For an informal discussion regarding the requirements of the role please contact Dr Emma Hodson-Tole (e.tole@mmu.ac.uk)

For more information and to apply online, visit http://www.mmu.ac.uk/jobs.

If you do not have access to the internet, or require an application in an alternative format, please contact Human Resources on 0161 247 3502 quoting the reference number G2/4617. Closing date for receipt of applications is midnight on 30 April 2014.

Manchester Metropolitan University is committed to creating a diverse environment where everybody is treated with dignity, fairness and respect. We welcome applications from all potential candidates.
1004907| Roche| Quality Site Head| Who we are At Roche, 80,000 people across 150 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity, and on seeing each other's differences as an advantage. To innovate healthcare, Roche has ambitious plans to keep learning and growing and is seeking people who have the same goals for themselves.

The following opportunity exists in our Florence, SC location:
Quality Site Head
Responsibilities: As a member of the Florence Leadership Team (FLT), reporting to the VP Global Quality Small Molecules, the Quality Site Head will be responsible for Quality and Compliance activities and decisions at the site. As an extended member of the Global Quality Small Molecules Leadership Team (PTCQ), the Quality Site Head will play an active role within the network and have the specific responsibility for network information and communication.
The Quality Site Head will direct activities within QA and QC in alignment with the Company Quality Policy to ensure that manufactured products meet Health Authority and Company standards and expectations. He/she will proactively prepare for and manage PAI and other Health Authority inspections, response preparation and CAPA as appropriate by assuring that the site is operating in an inspection- ready manner at all times. He/she will develop strategic goals and objectives to support the monitoring, review, testing and timely reporting on the quality of Roche products.
Requirements: Desired candidate will possess a bachelor's degree in Life Science, Pharmacy or related subject. PhD considered an advantage. Desired candidate will have about 15 years in the Pharma/Biopharmaceutical industry with at about ten years working in Quality, Compliance, Regulatory and/or Validation. He/she should have about eight years of experience at a management level. Sound knowledge of US, European and international regulations, and demonstrated experience and knowledge of Quality operations and processes is preferred.
Who you are You're someone who wants to influence your own development. You're looking for a company where you have the opportunity to pursue your interests across functions and geographies, and where a job title is not considered the final definition of who you are, but the starting point.
Job ID No.:
The next step is yours. To apply online today or learn about other exciting positions, please visit roche.taleo.net/careersection/test/jobapply.ftl lang=en&job=&src=11480/ Roche is an Equal Opportunity Employer fully committed to workplace diversity. Apply Here:
1004794| Amazon| Speech Scientist|

Amazon is looking for a passionate, talented and inventive Speech Scientist to join our team.

As a member of the technical team you will be responsible for;

YOUR RESPONSIBILITIES WILL INCLUDE


• Owning the strategic planning and project management for a variety of technical initiatives
• Providing business analysis using mathematical modeling tools to answer important questions
• Utilizing code (Java, C++ or another object oriented language) for modeling (optimization, simulation, statistical)
• Effectively communicating with senior management as well as with colleagues from computer science, technical research and business backgrounds

BASIC QUALIFICATIONS

  • Graduate degree in statistics, engineering, mathematics, or computer science and several years of related work experience OR a PhD and several years of related work experience
  • Ability to code with an object oriented language
  • Ability to develop system prototypes
  • Experience with mathematical libraries

PREFERRED QUALIFICATIONS

  • PhD highly desired
  • Project management experience desired for working on cross-functional projects
  • Software development experience
  • Exposure to scripting languages, relational databases and Linux
  • Experience working effectively with software engineering teams
  • Excellent written and verbal communication skills



Amazon is an equal opportunity employer.

5475| CSIRO, CSIRO Animal, Food and Health Sciences| Postdoctoral Fellow - Agricultural Systems Analyst / Modeller| We are currently looking for a highly motivated Postdoctoral Fellow - Agricultural Systems Analyst / Risk Modeller to make significant contributions to the research area of Food Systems and Environment. As part of a prolific, internationally recognised team you will contribute to integrated assessments of how to feed the increasing human population by 2050 in a more sustainable way. This multi-scale research programme spans from global assessments, to the evaluation of specific impacts of research and technology at the household levels in both the developing and the developed world.

CSIRO in collaboration with CGIAR partners and others, has invested significant resources in obtaining high resolution information on livelihood activities and household management strategies for parameterizing household, crop and livestock models for ex-ante assessment of adaptation and mitigation practices in Africa and parts of Asia. This position aims to fill this gap by developing and implementing state of the art risk management techniques in existing household, crops and livestock models.

Specifically you will:

* Work with existing modelling expertise across the Agricultural Productivity Flagship and elsewhere as part of a multi-disciplinary research team working on the economics, productivity and sustainability of farming systems in Australia and the developing world;
* Contribute to the development of the field of agricultural systems analysis, and the integrated economic and biophysical assessment of food systems and the environment;
* Work with a range of national and external partners in the assessment and quantification of risk and its impacts on potential choice of interventions in semi-arid systems (and others);
* Study the most efficient mechanisms for managing risk in smallholder systems under a variety of socio-economic scenarios;
* Contribute to the development of suitable household –level bioeconomic models to study niches for specific technologies and for assessing their impacts on incomes, productivity, food security, greenhouse gas emissions, and other environmental dimensions, and potential trade-offs arising from their adoption;
* Establish and maintain links with key stakeholders in government, industry and R&D organisations (national and internationally).

Location: St Lucia, Brisbane, QLD
Salary: AUD $78K to $88K p.a. plus up to 15.4% superannuation (pension fund)
Tenure: 3 Year Term
Ref No.: Q14/01090

To be considered you will hold a PhD degree (or equivalent experience) in agricultural production economics, geography, agricultural systems analysis, natural resource management.

You will also have:

* The ability to travel locally and internationally;
* Experience working on natural resources, economic and global change issues/policies for agriculture and livestock, with emphasis in developing country contexts;
* Experience and direct involvement in projects on risk management in agriculture and livestock systems;
* Knowledge of agricultural systems in both the developed and the developing world;
* Bio-economic modeling skills at different levels: from crops and livestock to the farm household and regional levels;
* Knowledge of global change integrated assessment models of agriculture, climate change and food security.

Owing to terms of the fellowship, candidates must not have more than 3 years of relevant Postdoctoral experience.

Applications close Tuesday 6th May 2014 (11:30pm Australian Eastern Standard Time).
5479| THE INSTITUTE OF CANCER RESEARCH, ICR, Division of Cancer Biology| Postdoctoral Training Fellow| The Institute of Cancer Research (ICR) is one of the world’s most influential cancer research institutes. Our mission is to make the discoveries that defeat cancer. We have a long and distinguished history of research with a major impact on the outcome for cancer patients. Our unique partnership with The Royal Marsden NHS Foundation Trust (RMH) makes us the largest comprehensive cancer centre in Europe, performing high quality original basic research and translational studies. Under the leadership of Chief Executive Professor Alan Ashworth FRS, we are committed to attracting, developing and retaining the best minds in the world. The ICR was ranked as the UK’s top academic research centre in the 2008 Higher Education Funding Council Research Assessment Exercise. Based on our publication record, citations and impact we rank among the world’s leading cancer research centres.

We are looking for a highly motivated postdoctoral fellow to work with the Development and Cancer Team led by Dr Amanda Swain as part of an ongoing funded project to study the development of steroid producing organs. The work will involve a combination of in vivo and in vitro approaches to analyse the development and regulation of steroid producing cells of the gonad and adrenal.

Candidates should possess a PhD in Molecular Biology, Cell Biology, Genetics or other relevant discipline, experience in molecular and cellular biology and histochemical techniques related to developmental biology and have a strong track record of high quality biomedical research. We are particularly interested in candidates with previous experience in developmental biology. In addition, an interest in endocrinology and use of in vivo genetically modified models would be advantageous.

Appointment will be on a Fixed Term Contract for 18 months with a starting salary in the range from £28,425 - £33,718 p.a. inclusive based on previous postdoctoral experience.

Informal enquires can be made to Dr Amanda Swain (Amanda.Swain@icr.ac.uk).
Please do not send your application to Dr Swain, formal applications must be submitted online.

To apply please submit your CV and covering letter (addressing where you meet the person specification and incl. the names and addresses of two referees) online via http://www.icr.ac.uk/jobsearch.

Job Ref. No. 1412175

Closing date: 24 April 2014
1004898| Center for Cancer Care| Chief Medical Physicist| Center for Cancer Care is currently recruiting for a Board Certified Chief Medical Physicist.
The position requires a PhD or Master's degree as well as 10 years of clinical experience. Position is responsible for all
aspects of clinical radiation oncology physics, quality assurance, treatment planning, radiation safety, and management of the physics staff.

Candidates should have experience in IMRT, IGRT, SRS, SBRT and HDR. We currently offer IMRT, IGRT, SBRT, SRS, HDR brachytherapy for gynecology treatments, 3-D conformal, forward-planning "field-in-field" IMRT for breast, and all standard, conventional external beam radiation therapy.
We have 6 Elekta
linear accelerators.
We utilize Pinnacle planning software and the Mosaiq record and verify system.
5502| Freie Universitaet Berlin, Dahlem Research School| 20 Incoming Postdoc Fellowships at Freie Universität Berlin - Call for Applications for 2015| The “Postdoc International” POINT research fellowship program – co-financed by the German Excellence Initiative and the Marie Curie Program of the European Commission – provides funding for outstanding postdoctoral researchers from all disciplines to conduct their own research project at Freie Universität Berlin.
The POINT program was designed by Dahlem Research School at Freie Universität Berlin to promote the further academic career development through research funding, a tailored qualification program and the opportunity to develop teaching and leadership skills. It also provides essential professional guidance on preparing grant proposals to support POINT fellows in obtaining funding for follow-up research projects at Freie Universität Berlin.

Eligibility
Starting in January 2015, each research fellowship will be awarded for 18 months. The call is open to experienced researchers of all disciplines and all nationalities who:
- hold a doctoral degree (the dissertation must be submitted)
- completed their doctoral degree no longer than 6 years before the deadline
- have not resided in Germany for longer than 12 months during the last 36 months
Female postdoctoral researchers and returnees from phases of international, inter-sectoral and/or non-academic mobility (such as researching outside Germany, working for industry or a career break e.g. due to family reasons) are specifically encouraged to apply.
Applicants have to submit a project plan based around the research fields/ key topics of the participating Excellence Projects or Focus Areas.

Deadline for applications: 4 July 2014, 12:00 noon (Berlin local time)

Funding
- 18 months, starting January 2015
- Employment contract at level TV-L FU E13 (of approx. 26.600 to 34.200 Euro net salary p.a.)
- Social security and health insurance included
- A research allowance for the duration of the project of 10.800 Euro for non lab-based/ 16.200 Euro for field trip-based/ 21.600 Euro for lab-based projects
- A monthly mobility allowance of 200 Euro and a one-time travel allowance

Application
To apply, candidates need to register with the DRS online application platform on the DRS website. Once registered, they should fill out the online application form and upload all required documents. Incomplete applications and applications submitted after the deadline will not be considered.
5459| University of Manchester, The Cancer Research UK Manchester Institute| POSTDOCTORAL SCIENTIST – Cell Division with Dr Iain Hagan|  Salary in the range of £28,500 - £38,000 dependent upon qualifications and experience
 Job Ref: MI/14/29
 3 year position

The Cancer Research UK Manchester Institute (www.cruk.manchester.ac.uk), an Institute of The University of Manchester (www.manchester.ac.uk), is a world-leading centre for excellence in cancer research. The Institute is core funded by Cancer Research UK (www.cancerresearchuk.org), the largest independent cancer research organisation in the world. We are adjacent to The Christie NHS Foundation Trust (www.christie.nhs.uk), one of the largest cancer treatment centres in Europe. These factors combine to provide an exceptional environment in which to pursue basic, translational and clinical research programmes.
Our aim is to understand the fundamental basis of cancer and apply that knowledge to developing new treatment strategies for cancer patients. Our advanced research programmes span a spectrum of cancer research, from the molecular and cellular basis of cancer through to drug discovery, translational research and clinical trials.
The Institute has outstanding laboratory facilities and exceptional core services, including next generation sequencing, microarrays, confocal microscopy, bioinformatics, histology and mass-spectrometry.
We are situated in Manchester, England, a vibrant and dynamic city that is surrounded by beautiful countryside and has excellent transport links both nationally and internationally.
A 3 year position is available in the laboratory of Iain Hagan to study the control of mitotic commitment and how this is modulated to entrain cell division to the particular environmental context. The ultimate aim would be to elucidate the mechanism by which eukaryotic cells commit to division and ensure that one copy of the genome goes to each daughter cell. A detailed characterisation of the function of the fission yeast mitotic regulator Cut12 will be conducted.
The successful applicant should have a PhD in Cell Biology, Biochemistry, Genetics or Molecular Biology. A background in Cell Cycle Control/Mitosis research is desirable but not required.
Informal enquiries should be directed to Iain Hagan Iain.Hagan@cruk.manchester.ac.uk

To apply for this position please visit our website: www.cruk.manchester.ac.uk

For applicants who are unable to download this information from our website, please contact HR department on 0161 446 3231, email: jobs@cruk.manchester.ac.uk to have this information sent by post.

Closing date: 28th April 2014
1004899| Confidential| Senior Director, Clinical Research&Development Job| Celgene is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health. We value our passion for patients, quest for innovation, spirit of independence and love of challenge. With a presence in more than 70 countries - and growing - we look for talented people to grow our business, advance our science and contribute to our unique culture.

Summary/Scope:
The Clinical Research Physician, Hematology/Oncology will be instrumental in supporting the growth of the Solid Tumors organization as it continues to build the value of its current products and develop new products. The incumbent will have hands-on responsibility designing and executing clinical trials, and running programs focused on assigned therapeutic areas. and will exhibit a passion for Phases 1 through 3, including biomarkers, proof-of-concept and full development.

Core Responsibilities:
Design and optimize clinical trial design and ensure clinical trials meet ethical and regulatory standards.
Lead the Clinical Protocol Team, including interactions with discovery, safety, marketing, regulatory, research and other functions.
Write protocols that are in-line with the overall indication strategy.
Present at Investigators' meetings.
Conduct medical review and interpretation of efficacy and safety data from clinical trials.
Have responsibility for the quality, coordination, medical accuracy and timeliness of clinical study reports.
Work with other Therapeutic Area Heads and team members to prepare abstracts, manuscripts and presentations for external meetings as well as author clinical sections of regulatory documents (IB, IND sections).
Assist senior management to oversee quality, coordination and timeliness of clinical sections of INDs, Investigator Brochures, CTAs, ISS's, ISE's, and clinical expert reports.
Present and discuss data and findings at relevant team, governance, KOL and regulatory meetings.
Establish and maintain working relationships with Study investigators, key opinion leaders, academicians, and Celgene Senior managers and department heads across the corporation
Ensure adherence to GCP/ICH and Celgene Standard Operating Procedure (SOP) standards.
Maintain clinical and scientific awareness in area of expertise.
Guide and influence the distribution and management of Clinical Research Scientists
Manage lifecycle requirements and plans for designated indications.

Celgene is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.

Celgene complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Celgene in the U.S.

*LI-KM1

Qualifications
Prerequisites: Minimum M.D. or PhD degree and substantial medical/clinical training in hematology/oncology or a related field
Minimum 5 years of experience designing, leading and managing significant clinical trials in hematology/oncology
Direct industry experience is preferred; substantial experience working on industry-sponsored trials will be considered.

Key Requirements/Knowledge:
Minimum M.D degree and substantial medical/clinical training in Therapeutic Area or a related field.
Minimum 5 years of experience designing, leading and managing significant clinical trials in the Therapeutic Area
Direct industry experience is preferred; substantial experience working on industry-sponsored trials will be considered.
Demonstrated understanding of drug development process.
Knowledge of Good Clinical Practices (GCP), FDA regulations and guidelines, and applicable international regulatory requirements.
Experience in designing Clinical trial strategies to obtain regulatory approval.
Ability to provide scientific and clinical expertise to a clinical development program and evaluate scientific and clinical strategies for a product.
Ability to develop and evaluate strategies for the clinical development of a designated indication and to critically evaluate outside expert advice.
Experience in Clinical project planning.
Experience working on global and complex Clinical trials.
Experience working effectively in a team/matrix environment.

Celgene Leadership Competencies
Drive Innovation
Shape Strategy
Attract and Develop Talent
Promote Open Communication
Create Global Mindset
Demonstrate Adaptability
Foster Risk Taking
Foster Teamwork

Competencies /Skills
Strong scientific/technical skills
Strong interpersonal capabilities and ability to build networks
Ability to anticipate and resolve problems
Ability to lead cross functional efforts and teams
Excellent verbal communication and technical writing skills
Ability to present clearly using scientific and clinical terminology
Excellent interpersonal skills and ability to communicate effectively with people in different functions
Sound organizational skills
Possesses sense of urgency and can take initiative
Ability to motivate team members
Project management skills and focus on delivery of results

Req ID:
Primary Location: United States-New Jersey-Summit
Job: Medical Operations
Organization: Celgene Corporation
Schedule: Regular
Shift: Standard
Employee Status: Director
Job Type: Full-time
Job Level: Day Job
Travel: Yes, 20 % of the Time
Job Posting: 2014-04-:00:00.0
1004910| AGILE| Senior Java Software Engineer|

Senior Java Software Engineer

Skills:

Object Oriented Design and Development (OOD), Java or C# (or an equivalent OO language), SQL, HTML5 and GIT a plus!

Summary

Roswell client is seeking a strong developer to join a talented technical team using the latest Java technologies along with Open Source tools for developing a Service Oriented solution. This is 50% Front End and 50% Back End. The ideal candidate is a true computer scientist, and has experience working in a small company writing commercial software or product/shrink-wrap software or SaaS. Client is always willing to look at new technologies so the developers have a lot of input into defining the technology stack. Flexible work environment and performance driven software company. This DIRECT HIRE/PERM position will prove technically challenging and rewarding. Our client values integrity, intelligence, loyalty and hard work, and in return, they offer interesting and challenging work where you are valued and will make a difference. If complicated algorithms, geometry, and obstacle recognition are your thing, then this is the place for you! TONS OF AUTONOMY.

Responsibilities

  • Engage in the design, implementation and deployment phases of SDLC.
  • Design and implement new features for deployment across product lines.
  • Extend and support existing products.
  • Perform and participate in code reviews.
  • Perform development, unit testing, and application testing individually and in collaboration with the team. 
  • Research and evaluate software (including open source libraries and 3rd party products) for inclusion in the development process.
  • Participate as a key contributor on a Scrum/Agile team.
  • Mentor and provide guidance and direction to junior members of the programming team.
  • Must be able to wear multiple hats and pitch in where needed.

Qualifications

  • Bachelor, Masters, or PhD degree in Computer Science, Engineering, related discipline
  • 5+ years of core development in Java, C#, or an equivalent modern OO programming language.
  • Experience with JavaScript.
  • Strong knowledge of SQL
  • Top-notch communication and conceptual skills.
  • Proven ability to meet tight deadlines and work effectively in a team environment. Deployed and managed software on Linux and Tomcat 7.

Desired

  • Experience with HTML 5.
  • Experience using GIT.
  • Experience with test driven design and tools such as JUNIT and experience with continuous integration environments and related tools.
  • Experience working in an Agile development environment.
  • Experience with image analysis and computational geometry.
  • Experience implementing numerical algorithms.

Benefits

Medical, Dental, Vision, 401K with company match, Casual Dress, Telecommute 2 days a week (after first 90 days), PTO 15 days first year

5470| University of Kansas, Department of Ecology and Evolutionary Biology and Kansas Biological Survey| Postdoctoral researcher| A postdoctoral position is available in the laboratory of Dr. Daniel Reuman in the Department of Ecology and Evolutionary biology and the Kansas Biological Survey at the University of Kansas (Lawrence, KS). The position is for two years with funding available for an extension for a third year pending good progress. Research will focus on software aspects of two large projects: 1) Ramifications of metapopulation synchrony through the complex North Sea and North Atlantic metacommunities in the face of climate change; and 2) Revealing the mechanisms linking the structure, functioning, and dynamics of whole ecological communities using likelihood. The researcher will be expected to contribute to software development for both projects, collaborating with teams of biologists, statisticians, and modellers and pursuing independent research questions. Candidates should have completed a PhD in biology with a quantitative focus, computer science, statistics, mathematics, or a related field, and should have a demonstrated interest in population, community, or global change ecology. Preferably the candidate will have experience in R, C, cluster computing, and implementing statistical inference techniques in software. See http://employment.ku.edu/staff/313BR for further details. Contact reuman@ku.edu with informal iquiries.
5482| AstraZeneca| US Postdoctoral Opportunity for student, AZ Neuroscience & Tufts University| Role of Usp14 inhibition in proteinopathies associated with progressive neurodegenerative disorders

AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialization of prescription medicines, primarily for the treatment of cardiovascular, metabolic, respiratory, inflammation, autoimmune, oncology, infection and neuroscience diseases. We are science led and operate in over 100 countries and our company is comprised of many voices, views and talents united by a common mission: helping people live healthier lives, embracing diverse perspectives, and working together to create a better future.

Join the next generation of scientists at a post-doctorate level and you'll thrive in state-of-the-art laboratories, grow within an entrepreneurial and collaborative culture, one that inspires leadership and independent thought, and connect with people across our global business. Here, employees like you are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.

This is a unique opportunity to work at the interface of academia and industry as part of a recently created group of scientists working collaboratively between AstraZeneca and Tufts Neuroscience. The project will be conducted in the Department of Neuroscience at Tufts University in the heart of Boston, supervised by Professor Steve Moss and in close collaboration with Steve Jacobsen from the AstraZeneca Neuroscience IMed.


Candidate Focus and Challenge

Failure of efficient protein clearance to prevent the accumulation of misfolded proteins is associated with several neurodegenerative proteinopathies. A working hypothesis is that Usp14, a deubiquitinating enzyme, shortens the polyubiquitin chain on misfolded proteins, thereby resulting in the premature release of the ubiquitin-conjugated protein and failure of proteasomal degradation. To determine whether knockdown of Usp14 activity promotes selective proteasomal degradation of misfolded proteins, AstraZeneca Neuroscience seeks a post-doctoral candidate who is interested in characterizing the accumulation and neuronal deficits associated with misfolded proteins, and exploring the potential effects of limiting Usp14 activity on protein degradation.

A successful candidate will:

• Design and conduct research to characterize protein accumulation and cellular/neuronal deficits attributed to misfolded proteins
• Characterize the effects of Usp14 knockdown on the degradation of these misfolded proteins and how clearance may rescue deficits
• Interact and collaborate with scientists across Tufts and AstraZeneca, become an active leader within the growing Tufts-AZ scientific community
• Publish scientific papers and attend conferences to communicate novel findings to the research community

Candidate Knowledge, Skills and Experience

Minimum experience

A PhD in biochemistry/neurobiology with experience in one or more of the following areas:
• Experience with biochemical and cellular analysis of misfolded proteins associated with human neurodegenerative diseases
• Experienced biochemist with strong background in proteasome function and mechanisms of protein degradation
• Experience with cell culture, molecular biology and viral expression techniques
• Experience in creating and using primary neuronal cultures and iPSC models for cellular and biochemical experiments
• Ability to design and carry out research independently
• Strong written and oral communication skills
• Ability to work effectively and collegially with colleagues and initiate collaboration


Preferred experience/requirements

• A strong scientific track record, as evidenced by published or accepted p
5451| University College London, UCL Biochemical Engineering| Postdoctoral Research Associate in Bioprocess Multivariate Statistics and Chemometrics| The appointment will be full time on UCL Grade 7. The salary range will be £32,699 - £39,523 per annum, inclusive of London Allowance.

To meet the many challenges in the development of antibody therapeutics, UCL’s Advanced Centre for Biochemical Engineering and MedImmune (Cambridge) have set up a joint MedImmune-UCL Centre of Excellence to advance the application of predictive multivariate decision-support tools in the bioprocessing sector.

An exceptional opportunity exists for a postdoctoral research associate to join the Centre of Excellence for a challenging multidisciplinary three-year programme. The postholder will be required to carry out research in the areas of data mining and of process synthesis, design, planning and optimisation. This will include leveraging experimental data with advanced data mining and multivariate statistical tools so as to derive an integrated set of predictive models for whole bioprocesses.

The postholder will be responsible for managing the co-ordination of associated MedImmune-sponsored doctoral students working on upstream and downstream operations of mammalian cell culture processes.

This post is funded for 3 years in the first instance and is available from 1st July 2014.

The candidate will possess an in-depth knowledge of the methods of multivariate statistical analysis and visualization research techniques, mathematical optimization and modelling, evolutionary optimization and multi-objective decision-making, with some background knowledge of biochemical engineering. Experience with multiple programming languages and database packages is also essential. A PhD degree in a relevant subject area is required (e.g. Biochemical Engineering, Chemical Engineering, Industrial Engineering, Computer Science).

Advanced research and project management skills are essential, as well as an ability to work in a multidisciplinary collaborative and teamwork environment with excellent interpersonal, written and verbal communication skills.

For further details about the vacancy and how to apply online please go to http://www.ucl.ac.uk/hr/jobs/ and search on Reference Number 1407506.

If you have any queries regarding the application process, please contact Imran Sayed i.sayed@ucl.ac.uk

Closing Date: 28th April 2014

Latest time for the submission of applications: 5pm.

UCL Taking Action for Equality
1004928| SEC Recruitment Ltd| Science Director - Credit And Risk|

A disruptive player within the personal finance market needs a Science Director (Research) with Qualitative Research experience and an MA/PhD in Psychometrics or Psychology to lead the development, delivery and strategic vision of their Analytics product.

The main purpose of this role will be to lead a team of Research Psychologists and Creative Product Developers, creating structure and driving change in a highly Matrix environment.

Other noticeable responsibilities include:

*Providing leadership of Qualitative Research activities
*Optimising and standardising the delivery and ongoing monitoring of Analytics products
*Maintain a robust environment in relation to Data Protection, Quality Standards and Compliance
*Support the development of next generation adaptive questionnaires

The successful Science Director will have the following key skills and experience
:
*Proven track record in a senior capacity within Qualitative Research with experience in Semiotics, Cultural Analysis and Ethnography
*MA/PhD qualified in Psychometrics or Psychology
*A statistical background with technical skills within R/SAS/MATLAB is desirable

This organisation has expanded out of their original office and has been growing at a phenomenal rate. They have really funky offices on the heart of Shoreditch and benefits that are usually associated with much larger companies. For immediate consideration, please call Joseph or send over a copy of your CV along with a brief covering note.

Key Words: Director, Science, Quantitative Research, Semiotics, Cultural Analysis, Ethnography, Psychometrics, Psychology

1004932| Visionaire Partners| Senior C++ Software Engineer - 3D/Point Cloud|

Senior C++ Developer - PointCloud

Fantastic opportunity for a Senior Software Engineer with strong C++, Point Cloud, and 3D development experience to join a dynamic team.

You will work on the design and development of the next generation of software products in 3D for mobile, web, and desktop. You will integrate 3D graphics with other systems (analytics, data management, etc.), improve Point Cloud processing, contribute to design and architecture, work on patent writing and review, contribute to the Point Cloud Library (PCL), and research emerging technologies.

This is a direct hire position based in the East Bay area of California. Excellent opportunity to work with a top notch team and take your career to the next level. The company has first class benefits and innovative culture and work environment. A preference for experience with global application development, GPU, SIMD, and a PhD. We will consider helping with relocation assistance.

REQUIRED EXPERIENCE:

  • 4+ years of C and C++ development of desktop 3D applications
  • 4+ years developing desktop 3D software (including spatial partitioning techniques, meshes, points, vectors, intersection test, etc.)
  • Point Cloud (including storage, rendering, and feature extraction)
  • Multi-threaded development
  • Object Oriented programming and architecture patterns
  • Ability to provide technical leadership
  • Excellent communication skills and very collaborative personality
1004849| Confidential| Manager, Sales Operations Job| Celgene is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health. We value our passion for patients, quest for innovation, spirit of independence and love of challenge. With a presence in more than 70 countries - and growing - we look for talented people to grow our business, advance our science and contribute to our unique culture.

In an effort to exceed strategic and operational requirements, the Manager, Sales Operations will support field based customers through analysis and reporting. This person must have extensive industry experience focused on delivering results within the areas of reporting and analytics, targeting and sizing/alignments.

Responsibilities include, but are not limited to, the following:
Key Sales Operation contact for Field based customers
Partner with Sales Management to identify and support key strategies to drive the brands strategic imperatives, with a strong focus on predictive analytics.
Provide statistical analysis to the Sales Operations Team.
Liaison to Sr. Management on key initiatives
Trouble-shoot and manage field based inquiries
Enhance reporting and analytical deliverables through user feedback as well as personal expertise.
Partner with the Sales Training department to develop all training for current and new field based employees on the reporting and analytical tools available.
Form cross-functional partnerships within the other areas of Sales Operations to share business updates and best practices.
Further develop analytical support team members through highly engaged coaching and mentoring
Other Sales Operations responsibilities as deemed necessary

Skills/Knowledge Required:
BS in relevant business or science major, MBA Preferred or PhD Statistics
Minimum of 3 years experience in Sales Operations
Strong sense of teamwork and collaboration skills
Thorough understanding of the integrated processes within Sales Operations
An extensive knowledge of Access and Excel and good knowledge of Word and PowerPoint and SAS a must
Strong analytical, problem-solving and decision-making skills
Excellent communication skills (both oral and written), with the ability to communicate across multiple functions and levels
25% Travel is required
Predictive Modeling knowledge a Must

Celgene is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.

Celgene complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Celgene in the U.S.

*LI-MR1

Qualifications
B.S. In business or science major; 3 years Sales Operations experience.

Req ID:
Primary Location: United States-New Jersey-Summit
Job: Marketing and Sales Excellence
Organization: Celgene Corporation
Schedule: Regular
Shift: Standard
Employee Status: Manager
Job Type: Full-time
Job Level: Day Job
Travel: Yes, 25 % of the Time
Job Posting: 2014-03-:00:00.0
5493| Cardiff University, School of Healthcare Sciences| Research Assistant (Rehabilitation)| The School of Healthcare Sciences, Cardiff University, conducts high quality research relevant to the clinical practice of nurses and allied healthcare professionals.

We are seeking a well-organised, motivated and flexible Research Assistant to contribute to research within movement analysis and virtual rehabilitation, carrying out supporting work that helps lead to the publishing of research in high-quality journals. The role holder will pursue excellence in rehabilitation research and inspire others to do the same.

The post holder will hold a BSc or MSc in a relevant field related to movement therapy, rehabilitation or movement research or equivalent experience. They will have good computer skills, particularly data acquisition, spreadsheets, word processing as well as proven communication skills including effective communication with patients.

Informal enquiries about the post may be directed to Professor Robert van Deursen, Professor of Rehabilitation Science (vandeursenr@cardiff.ac.uk).

This is a part-time post (0.5 FTE; 17.5 hours per week) and is fixed-term for twelve months from 1 May 2014 (or as soon as possible thereafter)

Applicants requesting external secondment from an NHS Health Board or Trust will be considered.

Salary range: £25,013 - £28,972 per annum, pro-rata for hours worked (Grade 5)

Date Advert Posted: 10 April 2014

Closing Date: Friday, 25 April 2014

Cardiff University reserves the right to close this vacancy early should sufficient applications be received.
1004931| TomTom International BV| C++ Software Engineer - Map Access and Search| We are looking for experienced engineers with background in C++ software development to join our navigation engine development team. Our team thrives on cooperation and is committed to implementing an innovative range of navigation software products.

The TomTom Navigation Product Unit is responsible for delivering software components for TomTom's Connected Navigation products such as portable navigation devices (Sat Nav), in-dash automotive systems, Android and iOS navigation applications; as well as our online assets like the Location Based Services platform which powers routes.tomtom.com and developer.tomtom.com. The foundation of these products is our industry leading navigation engine NavKit. NavKit provides a cross platform implementation of the complex domain logic and algorithms for routing, guidance, 3D map visualization, location search and map matched positioning that is required in a navigation application. Besides being a key enabler for our own products, NavKit is also distributed in the form of a software development kit. With the NavKit SDK, business partners may develop their own navigation application by building on TomTom's expertise in the navigation domain. Our business partners are among the biggest automotive and smartphone manufacturers in the world. Together we are tackling future challenges for the next generation of connected cars and highly automated vehicles (aka self-driving cars). Our recently released, all new TomTom GO is one of our NavKit-powered products and we're extremely proud of it.

Learn more about NavKit on YouTube: youtu.be/-FWMV3XzGMU

We develop NavKit in a lean-agile software development approach using methodologies from the Scaled Agile Framework (SAFe). Through the Agile Release Train we deliver NavKit releases on a regular basis - bringing new functionality to the market quickly that immediately reaches millions of consumers and makes the result of our work rewardingly tangible.

Within the NavKit organization we are looking for a C++ Software Engineer, ideally with experience in developing and implementing software for on- and off-board navigation systems, to work on our map access and search software. The experience (and future opportunities) may include complex algorithm development, optimization for embedded devices, solving scalability issues when dealing with huge amounts of static and dynamic map and traffic data, efficiently serving a rapidly increasing user base, developing a variety of novel algorithms on road networks and providing the best possible user experience to delight our customers. The navigation field is highly interesting and provides plenty of technical challenges, which will surely keep you and your team members engaged. Together you are tasked to drive innovation and to make our NavKit map access and search component best in class.

Our offer

- The chance to work in an agile team with an industry-leading navigation software stack
- Market rate salary&benefits (depending on experience and skills demonstrated)
- A challenging, fast moving and innovative work environment
- To work in the cutting-edge field of digital mapping, traffic and navigation solutions
- Based in Amsterdam

Your main tasks

- Design, implement and maintain state-of-the-art map access and search algorithms in C++
- Extend, improve and integrate map access and search algorithms in TomTom products for embedded and mobile devices as well as for server-based solutions
- Maintain our navigation software stack and contribute to its software and design quality; always strive to improve the quality of our software products; continuously improve our testing strategies and test coverage
- Create and share interface specifications and code documentation
- Follow our lean-agile development process and take an active role in our teamwork
- Collaborate with our navigation development teams in creating high quality products
- Develop and contribute to the long-term technical goals and strategies of our department

Your Profile
- You are a highly motivated and friendly individual with a strong background in C++ software development (3+ years experience)
- You have a university degree in computer science, discrete mathematics, or a closely related field. PhD is a plus
- You are fluent in C++ including templates, abstractions and efficient resource handling. Familiarity with the STL and knowledge of the Boost C++ Libraries is a plus
- You may be experienced in template meta-programming
- You know about C+ and you may know about coding standards such as Philips Healthcare C++ or MISRA C++
- You know about Linux based development environments and tools
- You are experienced in software development for server-based solutions
- You have extensive expertise in designing and implementing efficient algorithms, data structures and interfaces
- You know about at least one of the following fields: (reverse) geocoding, indexing, search algorithms, shortest paths, online algorithms or statistics
- You are familiar with test-driven development methodologies, automated software testing, and in particular with unit testing
- You have worked in continuous integration and delivery environments
- You may have working knowledge of Java, Android, Shell, Perl, Python or Ruby
- You may be experienced in developing multi-threaded applications
- You are able to maintain high accuracy and quality levels while working to tight deadlines and meeting the business requirements
- You are able to work as part of a self-organizing Scrum team in which you determine your tasks on a daily basis - this includes handling multiple tasks at the same time and working in a lively environment
- You may be familiar with lean-agile software development methodologies such as the Scaled Agile Framework (SAFe)
- You have good communication skills and an ability to work with architects, developers, test engineers, product managers, scrum masters and other team members
- You have a good command of English; both written&spoken

Business Unit/Department
The Navigation Product Unit is part of the TomTom Location Technology Products Unit and is responsible for developing key software products that together form our Connected Navigation Application (CNA). For our customers, bringing a CNA to market is both complex and expensive. The feature scope is ever expanding. For many people, smartphones are regarded as the benchmark for the user experience. End-user needs are changing rapidly as a result of the fast moving Consumer Electronics world. It is challenging to predict the winning user experience of the future. By delivering off-the-shelf software products that are easy to integrate and that are validated in our own consumer products, we help our customers to overcome these challenges and to deliver a Connected Navigation Application that meets consumer expectations.

Our Organisation
TomTom empowers movement. Every day millions of people around the world depend on TomTom to make smarter decisions. We design and develop innovative products that make it easy for people to keep moving towards their goals. Our map-based components include map content, online map-based services, real-time traffic, and navigation software. Our consumer products include PNDs, navigation apps, and GPS sports watches. Our main business products are custom in-dash navigation systems and a fleet management system, which is offered to fleet owners as an online service with integrated in-vehicle cellular devices. Our business consists of four customer facing business units: Consumer, Automotive, Licensing and Business Solutions. Founded in 1991 and headquartered in Amsterdam, we have 3,600 employees worldwide and sell our products in over 35 countries.

Interested?
If you would like to be part of this winning team and would like to help us further position ourselves as the authority in location and navigation solutions, please apply today!

We kindly ask you to complete the form and attachments in English.
Pre-employment screening of all external candidates is part of the selection process.
5498| MRC Functional Genomics Unit, University of Oxford| Postdoctoral Research Scientist - Neurological Disease Research| We are looking for a post-doctoral scientist to join Professor Dame Kay Davies’ group at the MRC Functional Genomics Unit. The post holder will join an active research team working on the analysis of mouse models of neurological disease, both neurodegenerative disorders and mental health. The aim of these studies is to understand the molecular mechanisms that underlie cell death and neuronal function and dysfunction in these conditions. The work uses a combination of molecular, cellular and in vivo behavioural methods to address these questions. Specifically, the post holder will be part of an on-going project examining novel stress response pathways in neurodegeneration.

The successful applicant should have a background in molecular / cell biology. Candidates should have a PhD / DPhil in the field of genetics, cell biology or molecular biology or be clinically qualified. Experience of confocal microscopy, tissue culture or rodent models of disease would be an advantage, although training will be given.

The Unit is embedded within the Department of Physiology, Anatomy and Genetics at the University of Oxford and is a world-renowned centre for research into neuromuscular and neurodegenerative disorders. We offer excellent laboratory facilities in the modern Henry Wellcome Building of Gene Function, Parks Road, Oxford, OX1 3QB. Additional information about the Unit can be found at www.mrcfgu.ox.ac.uk, whilst informal enquiries can be addressed to Professor Davies at kay.davies@dpag.ox.ac.uk. For further information about the Department or MRC please visit: http://www.dpag.ox.ac.uk or http://www.mrc.ac.uk respectively.

This post is available from 1st June 2014 and is funded by the MRC until 31 March 2016.

For further details and to apply for the post, please visit: https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=112863


The closing date for applications is midday on Thursday 15th May 2014.
Interviews to be held Tuesday 17th June 2014.
1004702| Monarch Recruitment NL | Software developer C# .Net, WPF, Winforms - Zuid Holland: Delft, Den H| Software developer C# .Net, WPF, Winforms - Zuid Holland: Delft, Den Haag, Rotterdam

My client delivers services to Oil&Gas companies and delivers high performance technology that adds value from oil and gas reservoirs. Their products are mainly aimed at improving productivity, lowering costs, reducing risk for activities related to increasing reservoir performance and hydrocarbon extraction.

Their software team is based in the Netherlands and mainly focuses on subsurface modeling systems, but also on their software development kit and their own framework. The subsurface modeling system helps clients to answer questions like: how many liters does this reservoir consist or how much can be produced? They mainly use windows applications, which are built in C#, C++ and SQL in a Scrum environment. The company culture is fairly relaxed and informal.

The team is looking for a wide range of developers: strong graphics skills, user experience, but also people with a thorough mathematics/physics background.

What will you do?
Developing and adding functionality to the software platform
Presenting ideas for system improvements, including cost proposals
Working closely with analysts, designers, management and staff
Producing detailed specifications and writing the program codes
Testing the product in controlled, real situations before going live

Your skills:
HBO+ in Computer science, Physics, Maths or related. Msc OR PhD is preferred.
Thorough knowledge of software architecture and parallel programming patterns
Excellent communication skills in English
Working knowledge of Microsoft technologies including Visual Studio, C# and a source code control system such as TFS
Either strong graphics programming skills and/or a strong mathematics/physics background
Experience in technical or scientific software engineering
Scrum/Agile experience is an advantage
MCSD Certification is an advantage

To apply, please apply through the website. For questions you can call .
5486| AstraZeneca| US Postdoctoral Opportunity for student, AZ Neuroscience & Tufts University| Exploring novel channelopathies that underlie erythromelalgia a chronic painful disorder of the peripheral nervous system

AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialization of prescription medicines, primarily for the treatment of cardiovascular, metabolic, respiratory, inflammation, autoimmune, oncology, infection and neuroscience diseases. We are science led and operate in over 100 countries and our company is comprised of many voices, views and talents united by a common mission: helping people live healthier lives, embracing diverse perspectives, and working together to create a better future.

Join the next generation of scientists at a post-doctorate level and you'll thrive in state-of-the-art laboratories, grow within an entrepreneurial and collaborative culture, one that inspires leadership and independent thought, and connect with people across our global business. Here, employees like you are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.

A unique opportunity to work at the interface of academia and industry as part of a recently created group of scientists working collaboratively between AstraZeneca and Tufts Neuroscience. The project will be conducted in the Department of Neuroscience at Tufts University in the heart of Boston, supervised by Professor Steve Moss and in close collaboration with Dr. Stephen Zicha from the AstraZeneca Neuroscience IMed.

Candidate Focus and Challenge

Erythromelalgia is a rare neurovascular disorder that causes extremely painful sensations in the extremities and is believed to be caused by mutations in the voltage-gated sodium channel subunit Nav1.7. AstraZeneca Neuroscience has identified novel mutations in other ion channels and is seeking a post-doctoral candidate who is interested in characterizing the functional effects of these mutations and exploring mechanisms of nociceptive signalling.

A successful candidate will:

• Design and conduct research to characterize the biophysical changes caused by novel mutations identified in both voltage- and ligand-gated ion channels
• Characterize the effect(s) that these mutated channels have on peripheral nerve excitability and how they might alter the pharmacology of novel analgesic therapeutics
• Interact and collaborate with scientists across Tufts and AstraZeneca. Become an active leader within the growing Tufts-AZ scientific community
• Publish scientific papers and attend conferences to communicate novel findings to the research community


Candidate Knowledge, Skills and Experience

Minimum experience

A PhD in pharmacology/neurophysiology with experience in one or more of the following areas:
• Experienced electrophysiologist, mainly in whole cell patch clamp
• Experience with cell culture and molecular biology techniques
• Experience in creating and using primary neuronal cultures for electrophysiology and pharmacology experiments
• Understanding of pain mechanisms and nociceptive signalling
• Ability to design and carry out research independently
• Strong written and oral communication skills
• Ability to work effectively and collegially with colleagues and initiate collaboration

Preferred experience/requirements

• A strong scientific track record, as evidenced by published or accepted papers in well recognized peer-reviewed journals, oral and/or poster presentations at scientific meetings.
• Strong passion & commitment to science, and ability to work well within a group/team environment.

Should you be selected for this Exploring novel channelopathies that underlie erythromelalgia, a chronic painful disorder of the peripheral
5480| AstraZeneca| US Postdoctoral Opportunity Oncology iMed- Cell uptake and target inhibition| Building fundamental mechanistic insights into productive cell uptake of short single strand oligonucleotides (ASOs)

At AstraZeneca We are seeking talented scientists who are interested in pursuing an academic-style Postdoc in a global pharmaceutical setting and contributing to AstraZeneca's commitment to delivering innovative medicines. This newly expanded internal pharmaceutical Postdoctoral research program spans multiple therapeutic areas and a wide range of scientific disciplines.

Your comprehensive training program includes a focus on drug discovery and development, as well as exposure to existing local and global Postdoctoral Research communities within AstraZeneca. Postdoctoral scientists will have the opportunity to conduct independent cutting-edge work in state-of-the-art laboratories while teaming with other AstraZeneca scientists.
Each Postdoctoral scientist will also be able to collaborate with a leading academic advisor who will provide further support and guidance. Additionally, the Postdoc will be encouraged to attend and present at international scientific conferences and publish high-profile papers.

The aim of this project is to explore the contribution of specific tumour microenvironment factors to the productive uptake of antisense oligonucleotides (ASOs) into tumor cells, leading to effective target knockdown. The focus will be on diffuse large B-cell lymphoma (DLBCL), and gaining insight into two potential mechanisms that can drive the productive uptake and intracellular trafficking of ASOs: extracellular matrix interactions and macrophage-mediated exosomal delivery.

Successful execution of the project requires:

Skill and expertise (some from graduate work, some to be gained during the postdoctoral research project) in the areas of:

• Extracellular matrix regulation of intracellular trafficking
• State-of-the-art intracellular imaging techniques
• Macrophage function / exosome biology
• Working collaboratively with internal and external experts in these areas.
• Synthesis of findings in these areas to gain novel insights into mechanisms that control ASO uptake and trafficking, leading to target knockdown in tumor cells
• Deliverables by the end of the project include:
• Novel findings that enhance the understanding of the mechanisms that drive cellular uptake and intracellular trafficking of ASOs
• Identification of the roles of specific proteins in tumor cells that could be expoited to improve uptake of ASOs, leading to improved target knockdown and activity
• Share progress with AstraZeneca collaborators in oligonucleotide therapeutic programs, including Isis and Regulus
• Minimum of one publication in a top tier, peer reviewed journal
• Presentation of findings at a major cancer, cell biology, or oligonucleotide focused international meeting
• The results of this research have the potential to lead to therapeutic approaches that enhance productive uptake of ASOs, including the potential to direct the chemistry and design of oligonucleotides to maximize productive uptake for existing programs, and to enable selection of patients most likely to respond to ASO therapy


Candidate Knowledge, Skills and Experience

Minimum experience and expertise:

• Recent PhD, with research focused in the areas of extracellular matrix interactions, intracellular trafficking, and/or macrophage biology in oncology
• Papers in one or more of the above areas published or accepted in peer-reviewed journals
• Expertise in cell biology techniques
• Ability to develop and test hypotheses based on observations from multiple disciplines
• Additional desired (but not required) experience:
• Expertise with intracellular imaging techniques
• Experience w
1004914| Non-Stop Recruitment| Oncology Medical Affairs Director, Switzerland| As Regional Medical Affairs Director you are responsible for the development and execution of Medical Affairs plans for Europe. You will be offer scientific expertise to the brand teams, and give direction to the country medical organisations for country medical affairs activities relevant for in-line and late-stage development products in their franchise. You will be responsible for Scientific Leadership in their regions. This position will report directly to the Head of Oncology Medical Affairs





Qualifications

* Education Minimum Requirement: MD, PhD or PharmD
* 4 years pharmaceutical or related industry experience in Oncology with proven track record of contribution to commercial, medical and/or clinical development strategies
* KOL identification, development and management expertise
* Proven ability to effectively communicate information at management level, with public groups and to scientific leaders.



Desired Experience and Skills

* Specialist training and/or clinical experience in oncology
* Recognized expertise through 5 years clinical and/or research experience in therapy area
* Strategic thinking, specifically related to life-cycle management strategy and execution



This is a full time, permanent position based out of our clients offices in the Zurich region offering a strong basic salary in addition to competitive fringe benefits



For more information call Bernardo Reveco on or alternatively send your latest CV to .



For latest industry news and vacancies add me on LinkedInch.linkedin.com/in/bernardoreveco/
5460| Institute of Chemical Research of Catalonia| Postdoctoral Mobility Programme (ICIQ-IPMP)| The third call of the ICIQ international postdoctoral mobility programme (ICIQ-IPMP) consists of the following 10 positions for a two year postdoctoral stay:

Position 1: Molecular Vessels. Mentor/Supervisor: Prof. Pau Ballester

Position 2: Computational Modeling of the Properties and Reactivity of Molecular Systems in Confined Spaces. Mentor/Supervisor: Prof. Carles Bo

Position 3: New Reactions Catalyzed by Group 10 Metal Complexes. Mentor/Supervisor: Prof. Antonio M. Echavarren

Position 4: Processing of High-Surface Area Electrodes for Catalytic Hydrogen Production. Mentor/Supervisor: Dr. José-Ramón Galán-Mascarós

Position 5: Molecular Redox Catalysis. Mentor/Supervisor: Prof. Antoni Llobet

Position 6: Theoretical Modelling of Biomass Transformations. Mentor/Supervisor: Prof. Núria López

Position 7: Metal-Catalyzed Reductive Cleavage of Electrophilic Coupling Partners. Mentor/Supervisor: Prof. Rubén Martín

Position 8: Photochemical Asymmetric Organocatalytic Processes. Mentor/Supervisor: Prof. Paolo Melchiorre

Position 9: Asymmetric Catalysis with Supported Systems for the Development of Continuous Flow Processes. Mentor/Supervisor: Prof. Miquel À. Pericàs

Position 10: Continuous Photo- and Electrocatalyic Conversion of Carbon Dioxide. Mentor/Supervisor: Dr. Atsushi Urakawa

The Institute of Chemical Research of Catalonia (ICIQ) is a public foundation devoted to research in the field of chemistry. Research is centered in three main areas: Catalysis of the chemical processes, the Institute’s most extensive line of research, as a key technology for clean and sustainable production; supramolecular chemistry as an entry to molecular nanotechnology; and renewable energies with an approach from chemistry science.

ICIQ’s headquarters are located in the Mediterranean city of Tarragona at 80 Km south from Barcelona in Spain, in a building with a build-up area of 12,800 sqm which accommodate 26 research laboratories, including 6 labs from ICIQ’s business incubator.

The programme is open to researchers from any nationality that fulfill the following eligibility criteria: a) Academic background: Candidates must hold a PhD at the time of the deadline for submission of applications. The PhD cannot be awarded more than four years before the deadline for submission of applications. Candidates who have performed the PhD thesis at the ICIQ will not be eligible. b) Mobility: Candidates must not have resided or carried out their main activity in Spain for more than 12 months in the 2 years immediately prior to the deadline for submission of applications.

Applications to the ICIQ-IPMP second call must be submitted online before May 31st 2014, 23:59 (local time), completing the online application form.

For detailed information of the programme and for applying please visit http://ipmp.iciq.es

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