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1037823| Software Specialists| Advanced Manufacturing Engineer|


  • Complete risk retirement testing, tooling and fixturing design and implementation, equipment development and qualification, process development and qualification activities for introduction of new product design in existing manufacturing line. Should have demonstrated competencies in these areas through previous work experience. As part of this role, must use Quality Management System and Good Manufacturing Practices for FDA regulated Medical Device Manufacturing to complete said qualification and validation activities. Interface with partners across Engineering, Advanced Manufacturing Engineering and Manufacturing to coordinate and execute work.

Key responsibilities/essential functions include:

  • Develop new or update existing fixtures to retrofit existing manufacturing line/process for a new product design
  • Complete process development and testing activities to define how to revise existing manufacturing line/process for a new product design
  • Based on process development activities, complete updated equipment qualification and process validations to qualify the new product design on the existing manufacturing line
  • Utilize Lean Six Sigma and Digital tools in development to ensure Design for Manufacturing across all processes and equipment. Ensure early focus on manufacturability in new product programs. Drive rigor in process capability assessment, process layout, tooling and equipment development and QMS Design Transfer execution
  • Ensure regulatory compliance through Qualification & Validation. Responsible for ensuring rigor in determining processes requiring validation, development of plans and analysis criteria, execution and final analysis and acceptance

Quality Specific Goals:

  • Aware of and comply with the GEHC Quality Manual, Quality Management System, Quality Management Policy, Quality Goals, and applicable laws and regulations as they apply to this job type/position
  • Complete all planned Quality & Compliance training within the defined deadlines
  • Identify and report any quality or compliance concerns and take immediate corrective action as required
  • Knowledge and understanding of document control, design transfer, verification, validation, acceptance activity, DMR, DHR and electronic signature requirements to ensure that product, equipment, tools, processes, software, training and documentation meet requirements

Required Qualifications:

  • B.S. Degree in Mechanical, Electrical, Industrial Engineering or related technical degree and 3 years' experience or Associates Degree and 5 years' experience or High School diploma with 7 years of experience in production, engineering or troubleshooting
  • Previous work experiences with ownership or qualification of manufacturing tools/fixtures, equipment and processes.
  • Demonstrated troubleshooting, analytical and planning skills
  • Ability to work independently
  • Demonstrated strong communication skills (written and verbal) to all levels of the organization
  • Ability to identify and implement Best Practices

Preferred Qualifications:

  • MS/PHD in technical concentration/field
  • 7+ years industrial experience in Manufacturing Engineering
  • 6-sigma DMAIC & DFSS certified
  • Experiences in Process Intensive manufacturing
  • Product and Process Development experience
  • Solid working knowledge of GEHC QMS procedures for GMP
  • Experienced developing tools and templates
  • Demonstrated program or project management skills
  • Demonstrated experience owning production processes/growing capability in yield and quality
  • Experience working with global teams
6989| University of Cambridge, Department of Phrmacology| Postdoctoral posts in calcium signalling| Applications are invited for two postdoctoral posts in calcium signalling, one of which will focus on lysosomes, to work in the laboratory of Prof. Colin Taylor at the Department of Pharmacology, University of Cambridge. The lab combines diverse approaches to examine the structural basis of intracellular calcium signalling and it enjoys collaborations with labs in other disciplines.

Applicants will have, or be close to obtaining, a PhD. For one post, experience with advanced optical microscopy (TIRFM, STORM) and quantitative image analysis is essential. Applications for both posts are encouraged from applicants familiar with calcium signalling or lysosomal biology, or with experience in other areas (eg, biophysics, cell biology, stem cells) and a willingness to apply their expertise to calcium signalling.

The appointees will be enthusiastic, careful and methodical, ready to accept responsibility individually and as part of a team, self-motivated, able to organise, perform and analyse experiments with considerable independence, engaged with the literature, and keen to combine different approaches to explore mechanisms of calcium signalling.

Funds for these posts are available for up to 3 years with effect from 1 February 2017 or as soon as possible thereafter. Starting salary will be within the range £29,301 to £38,183 pa.

The key duties require the development and execution of a research project, but the appointees will also be involved with our outreach activities, contribute to the activities of others in the lab, and take a share of communal lab responsibilities.

Please apply online: http://www.jobs.cam.ac.uk/job/12245. This will direct you to the University's Web Recruitment System, where you will need to register an account and log in before completing the online application form. For the online application you will need to provide your personal details, names and e-mail addresses of two referees familiar with your recent research, CV, publications and a cover letter (including a description of your experience as it relates to the job specifications). For enquiries about the online application process, please contact Ms Amparo Saez ([email protected]).

The deadline for receipt of applications is 23 December, 2016. Interviews of short-listed candidates will take place in early January.

The Managers of the Herchel Smith Postdoctoral Research Fellowships Fund invite applications for a Postdoctoral Research Fellowship, tenable from 1 October 2017, to pursue research in the general field of Condensed Matter Physics or Materials Science. The Fellowship is intended to enable an outstanding and highly motivated scholar who has demonstrated a capacity for independent research to focus exclusively on research at an early stage of their career, to develop academic potential, and to produce work of an international standard within the field. The Fellow will be assigned to and work in collaboration with an established research group within either the Department of Physics or the Department of Materials Science and Metallurgy, depending on their field of research.

In accordance with Dr Smith's Will, candidates must have obtained their PhD or equivalent at any university, but normally excluding Cambridge and Harvard. Fellowships can only be offered to those with less than three years' postdoctoral experience at the time the Fellowship is taken up. In addition to holding a PhD or equivalent, candidates must provide evidence of: outstanding academic excellence; a high-quality and original research proposal; and evidence of their potential as an independent researcher. The stipend will be on the University's Research Associate scale, currently between £29,301 and £38,183 per annum, and there is a research allowance of £15,000 per annum.

The funds for this post are available for a maximum of three years.

You will need to upload: Curriculum Vitae: A full CV which should outline your academic career, qualifications and list your publications to date (please do not include papers in preparation). It should be a maximum of two pages. Project Summary: A one page summary of your proposed project, clearly indicating your general field (Condensed Matter Physics or Materials), and specific area of interest near the top. Project Description: A detailed description of your proposed project. It is advised that you consult the departmental websites and similar resources to ensure that your proposal is appropriately related to the research interest of the department in which you wish to work. Publications: Hyperlinks to your three best publications in relation to this application. Please do not upload copies. Referees: Please ask the three referees whom you name in the Cover Sheet to supply references by 16 January 2017. You should supply referees with your project description to assist them in writing their references.

Applications are particularly welcome from those who can demonstrate commitment to the spirit of both Departments' Athena SWAN aspirations to support the advancement of women's careers in science, and to the University's wider equality and diversity obligations.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

For information about the Department of Physics, see: http://www.phy.cam.ac.uk/ Enquiries about applications in the field of Condensed Matter Physics can be addressed to Professor M A Parker, Head of Department via [email protected] For information about the Department of Materials Science and Metallurgy, see: https://www.msm.cam.ac.uk/

Enquiries about applications in the field of Materials can be addressed to Professor M G Blamire, Head of Department via [email protected]

Please quote reference KA10895 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
6981| Hamad Bin Khalifa University, Information Communication Technologies College of Science and Engineering| Postdoctoral Research Position in Human Computer Interaction and Inclusive Design| Position overview:
The ICT research group at HBKU is currently recruiting a postdoctoral researcher in the area of Human-Computer Interaction (HCI). The ongoing research aim is to explore and demonstrate how HCI as a field of applied enquiry can contribute to building an inclusive, more accessible, and sustainable future for Qatar and the world. In an era of big data, in which technology is integrated into nearly every aspect of life, several demographic groups remain unconsidered. Computing issues related to user groups such as children, the elderly, and people with different disabilities are rarely surveyed in computing research. The aim of this research work is to build upon the existing body of HCI knowledge from an inclusive perspective.

Example areas you might work in include:
• Researching, evaluating and supporting different applications of cross-modal interaction: when people using different interaction modalities (i.e. visual/audio/haptic) work together on common tasks using a variety of platforms.
• Conducting Human-Computer Interaction research with people with disabilities in order to explore and address accessibility issues in diverse contexts and settings.
• Working towards involving inclusive design and evaluation approaches in HCI research.
• Investigating the role of social media and its uses for non-standard populations.

The successful candidate will be working under the guidance of Dr Dena Al Thani.

Job summary/basic function:
The candidate will be responsible for conducting research and mentoring MS and PhD students in research projects on Human-Computer Interaction, interaction design, and inclusive design. The candidate will also be involved in seeking funding and will have the opportunity to develop their lecturing experience. HBKU offers a very competitive compensation package that includes an attractive salary and many generous benefits.
6992| National Physics Laboratory| Method Development for 3D Woven Composite Materials| Job Ref: 65182
Job Title: Post Doc: Method Development for 3D Woven Composite Materials
Location: Teddington
Type: Fixed Term
Closing date: 3rd January 2017

Job Description
The UK's National Physical Laboratory (NPL) sits at the intersection between scientific discovery and real world application. One of the top three National Measurement Institutes (NMIs) in the world, we now have a regional presence and strategic relationships with Surrey and Strathclyde Universities. Our expertise and original research have benefited UK citizens and the UK economy for over a century. A 1-year post-doctoral opportunity exists for a bright and enthusiastic individual within the Advanced Materials Characterisation Group within the Materials Division of the National Physical Laboratory (NPL), Teddington.

You’ll be part of a team working on developing new and existing test methods and standards for characterising the mechanical properties of new breeds of 3D fibre-reinforced (woven, tufted, stitched, pinned etc.) polymer matrix composite materials which are most notably seeing application in the aerospace, marine and renewable energy (wind, wave) industry sectors. In addition to mechanical testing, your work will include an assessment of the issues associated with non-destructive testing (NDT) of such materials and the suitability of mechanical property data in conjunction with current modelling approaches for 3D reinforced materials.- Background in 3D woven composite architectures
- Experience in failure analysis of composites via the use of destructive (optical, scanning electron microscopy) and non-destructive evaluation (NDE) techniques desirable
- PhD/EngD in Engineering or Material Science or equivalent industry training
- Background in Mechanical testing, ideally with FE modelling experience Based in a unique, purpose-built research environment, we are located in beautiful surroundings on the edge of Bushy Park, south-west London with a host of onsite facilities. These include a subsidised crèche, restaurant, free parking and our own sports and social club.

NPL Management Limited is committed to supporting its people to develop both personally and professionally and is committed to equal opportunities. NPL Management Limited is a Stonewall Diversity Champion and an Institute of Physics Project Juno Supporter.
6982| Royal College of Surgeons in Ireland RSCI, School of Pharmacy| Postdoctoral Researcher (Pharmacoepidemiology or Biostatistics)| Tenure: Specified Purpose Contract (3 years)
Reporting to: Dr. Gráinne Cousins

The Royal College of Surgeons in Ireland (RCSI) is a private, self-financing, not-for-profit medical and surgical college headquartered in Dublin (Ireland) with global reach through its overseas medical universities and health care centres in the Middle East, the Far East and Africa. Since its foundation in 1784, it has played a leadership role in Irish surgical and medical education. Currently, it operates the largest Medical School in Ireland and provides undergraduate education in Physiotherapy, Pharmacy, and Nursing. In addition to Surgery, it also provides postgraduate training and education in Radiology, Dentistry, Nursing & Midwifery, Sports and Exercise Medicine, Healthcare Management and Leadership, and has an Institute of Research.

RCSI recognises that excellence in research is critical to the quality of its educational activities, its credibility, and, overall, to its mission to enhance human health. Recently, RCSI has implemented a new research strategy that will build upon its strength in translational biomedical and clinical research to deliver transformational, high impact changes in health care. Targeting both Irish national and EU funding, along with increased collaboration with industry, is a major part of the RCSI research strategy. Forging increased collaboration between RCSI PIs and industry is of critical importance to achieving success in this area.

The research group of Dr. Gráinne Cousins at the RCSI School of Pharmacy aims to generate evidence based standards for the quality of care in opioid substitution treatment, which will inform future policy decisions on initiatives to reduce the risk of mortality associated with opioid substitution treatment, and to provide a better understanding of progression pathways within addiction services. As part of a Health Research Board (HRB) funded Health Research Award we are searching for a highly motivated post-doctoral researcher to lead on a national record-linkage study.

To perform record linkage and data analysis on the HRB-funded research program of Dr. Gráinne Cousins regarding opioid substitution treatment: mortality and progression pathways, and to oversee the delivery of this national record-linkage study.

Specifically the duties of the post will include
Position specification

• Provide epidemiologic expertise and support in developing a national longitudinal cohort of patients attending specialist addiction outpatient services
• Perform record linkage of multiple national databases, including national prescribing data and mortality data over a five year observation period
• Ensure accuracy and consistency of all processes
• Manage data, run analyses and critically review results
• Present regular progress reports to the multidisciplinary research team
• Draft reports and manuscripts and other forms of dissemination
• Perform such other duties as may be required from time to time

Person Specification:
The successful candidate should be able to demonstrate the following:
• A PhD in epidemiology, pharmacoepidemiology, biostatistics or related subject is desirable
• Proven ability to perform statistical analyses and good programming skills in Stata or SAS or equivalent
• Prior experience working with large datasets and evidence of peer-reviewed publications
• Good communication skills
• Ability to take direction and meet deadlines
• Strong organisational and administrative skills with the ability to prioritise objectives
• The ability to work on one’s own initiative as well as in a team environment
• Can operate flexibility within a busy environment; can shift focus when required
• Willingness to undertake training and career development

Application Process:
Please apply online with your CV and Covering Letter no later than 5pm on Friday January 6th 2017.
Informal Enquiries can be directed, in advance of the above closing date, to Dr. Gráinne Cousins at [email protected]
6988| ICR, Genetics & Epidemiology| Post Doctoral Training Fellow in Testicular Cancer Team| A postdoctoral research position is available to work on projects to identify and explore the functional basis of mutations associated with Testicular Germ Cell Tumour (TGCT). We seek a highly motivated candidate with a PhD and background in genomics and molecular biology. The successful candidate will lead on the TGCT laboratory and analytical work, supported by a Scientific Officer. The post is situated within and supported by the Houlston Molecular and Population Genetics Team, a large group with broad bioinformatics and wet-lab expertise in which novel analytical approaches to susceptibility, somatic and functional genomic are applied across a range of tumour types. This is an ideal opportunity for a highly skilled post-doctoral researcher to enjoy autonomy, varied laboratory and analytical projects and rich opportunity for primary authorships, supported and educated by the work and expertise of the larger group. Applicants should have broad laboratory skills as well as experience of applying statistical and bioinformatics analyses to genomic data.
The Testicular Cancer Team at the ICR has had lead the world field in the identification and characterisation of genes and variants that predispose to testicular cancer, including publication of the first large-scale NGS analysis of TGC tumours, the first large-scale WES analysis of TGC susceptibility and the largest GWAS analyses for TGCT (see recent publications ).
We hold >10,000 samples from men with TGCT, far and away the world’s largest sample series. We have GWAS data from >5000 cases of TGCT, germline exome data on >1000 cases of TGCT and are initiating WGS of TGCT cases. We also have large series of matched tumour and germline pairs and WES data on unselected and platinum resistant TGCTs. We have lead a number of successful international collaborative experiments and currently work within an active international consortium.

The post-holder will work on varied projects directed towards identifying mutations contributing to the development of Testicular Germ Cell Tumour (TGCT) and exploring their functional basis.
Primarily the project will involve:
(i) Applying a range of laboratory approaches to functionally characterise the mechanisms and pathways by which germline variants confer susceptibility to TGCT
(ii) Application of WES, WGS and GWAS approaches to identify and validate novel germline variants contributing to susceptibility to TGCT
In addition, for an applicant with appropriate interest and experience, there are opportunities for:
(iii) Integrating NGS sequencing and Oncoscan array genotyping to identify and validate novel somatic variants in platinum resistant TGCTs.
(iv) Applying bioinformatic and laboratory approaches to functionally characterise the mechanisms and pathways by which mutations contribute to the pathogenesis and drug resistance of TGCT.
The post-holder would be expected to bring genomic and molecular biology research experience to studies. The post-holder would be expected to bring well-developed skills in data analysis and bioinformatics to studies, although there is very strong bioinformatics support within the group by which these skills can be further nurtured. The post-holder will be expected to interact with, and supervise, junior team members, together with other senior researchers.
Please click apply for further information and to apply
6996| Queen Mary University of London, School of Biological and Chemical Sciences| Postdoctoral Research Fellow| A Postdoctoral Research Assistant position is available at Queen Mary University of London (QMUL), to undertake research on the navigation of flying bees and its neural underpinnings. This research position is offered within the School of Biological and Chemical Sciences at QMUL and forms part of the project entitled ‘Brains-On-Board – Neuromorphic Control of Flying Robots’, a multi-university collaboration aiming to create robotic controllers that will enable autonomous robots with the navigational and learning abilities of a honeybee. It involves five research groups at the University of Sheffield, Queen Mary University of London, and the University of Sussex performing research whose goal is biomimetic robot control and which will combine the study of insect visual orientation with autonomous robotics, computational neuroscience, and accelerated neural network simulations on GPU architectures.

The work will be performed under the supervision of Prof Lars Chittka (QMUL). The work involves both laboratory work on the orientation of bees (at QMUL) as well as field work which will mostly take place at Rothamsted Research near Harpenden, North of London. The main aim of this project will be to use newly developed radar technology to track multiple pollinating bees over large distances and over extended periods, to study mechanisms of their orientation, as well as their interactions with flowers and with other pollinators. Specific tasks will include monitoring of bee behaviour using advanced tracking technology, data analysis and manuscript writing, maintenance of bee colonies, tagging bees, and the supervision of small teams of undergraduates and research technicians. Candidates should have a PhD in biology, computer science or a related discipline. Experience with the subject of bee behaviour, or computational neuroscience will be an advantage. A good record of peer-reviewed papers in the field is essential.

The position is full-time, fixed term for 24 months, with the possibility of an extension up to 5 years. The position is available from the 01/01/2017 or as soon as possible thereafter. The starting salary is £44,815 per annum depending on experience and is inclusive of London allowance. Benefits include 30 days annual leave, defined benefit pension scheme and an interest–free season ticket loan.

Candidates must be able to demonstrate their eligibility to work in the UK in accordance with the Immigration, Asylum and Nationality Act 2006. Where required this may include entry clearance or continued leave to remain under the Points Based Immigration Scheme.

The School and Athena SWAN Charter for Women in Science
The School holds a Silver Athena SWAN Award and is committed to Athena SWAN principles to promote women in science.

For further information about the School, please see http://www.sbcs.qmul.ac.uk
To apply, please visit the Human Resources website on http://www.jobs.qmul.ac.uk and search for reference QMUL10311.

Application enquiries should be directed to [email protected]

The closing date for applications is 28 December 2016 Interviews will be held shortly thereafter.

Valuing Diversity & Committed to Equality
1037817| Provide Consulting Ltd| Computer Vision Research Engineer|

Research Engineer
£45,000 - £70,000

Are you a Computer Vision Engineer who enjoys doing great work that will change the world? Do you want to have your ideas turned into patents and papers and grow your skills in a company where personal development and growth is a high priority? An exciting opportunity has arisen for a Computer Vision Research Engineer to research and develop new algorithms for a medical device software product that turns cameras into health monitors, enabling video from cameras to read the vital signs (eg Heart Rate and Respiratory Rate) of people that the camera can see.

You will have the chance to research and develop new algorithms, design and run your own experiments and get to include your new algorithms in the final software product in an environment that allows access leading edge tools, equipment, software and many Peta Bytes of research data. The Computer Vision Research Engineer will collaborate with other researchers and software engineers through an environment that encourages sharing of ideas, challenges and in planning new work.

It is essential that the successful Computer Vision Research Engineer has a PhD, PostDoc or equivalent industrial research skills in Computer Vision, specialising in video analysis (eg face or limb tracking as opposed to static image analysis) as well as experience of
* Signal processing of time varying signals
* Machine Learning
* MATLAB/Octave or R and associated appropriate toolboxes and libraries

It would be highly beneficial for the Computer Vision Research Engineer to have
* Cross platform C++ 11/14 programming and/or Boost, STL and OpenCV
* Experience of Vision systems, cameras and illumination
* Exposure to test driven design/development with code quality and agile tools

1037832| Vertus Partners| Quant Analyst - XVA (CVA/FVA) - Investment Banking - London|

Quant Analyst - XVA (CVA/FVA) - Investment Banking - London

Our client, a leading Investment Bank, requires an experienced Quant Analyst to join an established and high calibre Derivatives Pricing Quant Team.

The successful candidate will focus on meeting the requirements of the BCBS 261 new value adjustment focusing specifically on calculating the Margin Valuation Adjustment. This will involve looking at formulating, documenting and testing new solutions and then implementing into the functional library.

Candidates must have:

  • Strong and demonstrable track record working as a Quant Analyst within the XVA space (CVA/FVA)
  • Strong C++ coding skills required (to deliver tools via C++ library)
  • Strong numerical academic background with Masters or PhD in Maths, Statistics or Physics
  • Good understanding of Inflation Swaps
  • Strong background in stochastic calculus
  • This role could also suit someone who is working within a derivatives pricing team (ideally Interest Rates) and keen to move into the XVA space

7000| Medical Research Council, Toxicology Unit| Postdoctoral Research Scientist| Postdoctoral Research Scientist
Fixed Term for 5 years
Salary £28,935 - £32,648
Hours: Full Time

The role of the transfer RNA repertoire in generating secretory phenotypes during epithelial homeostasis and cancer

Professor Martin Bushell (MRC Toxicology Unit Leicester)
In collaboration with Profs Jim Norman & Owen Sansom (Beatson Institute, Glasgow)

The Medical Research Council Toxicology Unit, (currently located at the University of Leicester but relocating to the University of Cambridge early 2020), is an internationally renowned institution focussed on the delivery of field-changing mechanistic insights into toxicology and disease. The Toxicology Unit is equipped with state-of-the-art facilities and provides a supportive and learning environment helping postdoctoral scientists to establish themselves as successful research scientists in their chosen field.

We are seeking an ambitious postdoctoral fellow to work on a research project investigating how genetic alterations to the tRNA repertoire influence ribosome function to generate secretory phenotypes during intestinal differentiation & fibroblast activation, and how this can generate microenvironments that promote cancer progression. The post holder will join the MicroRNA Regulation of Gene Expression group led by Professor Martin Bushell and work in collaboration with Profs. Jim Norman and Owen Sansom at the Beatson Institute in Glasgow. The project will be of interest to those seeking to work on novel aspects of cell biology in the context of cancer and wishing to undertake cross-disciplinary approaches to medical science and cancer research.

Candidates should have completed, or be about to complete, a PhD in a field relevant to mRNA biology and have published primary research papers (or have these papers in revision/in press) on relevant topics. An understanding of the mechanisms underlying cancer together with expertise in translational control, deep sequencing/high throughput methodologies and mammalian cell culture is essential. Experience of ribosome profiling and bioinformatics would be advantageous.

The MRC is a unique working environment where our researchers are rewarded by world class innovation and collaboration opportunities that the MRC name brings. Choosing to come to work at the MRC means that you will have access to a whole host of benefits from a final salary pension scheme and excellent holiday entitlement to access to employee shopping/travel discounts and salary sacrifice cycle to work scheme and childcare vouchers, as well as the chance to put the MRC on your CV in the future.

Closing date for applications: 6th January 2017

For more information please visit: http://tox.mrc.ac.uk/research/bushell-group/

Your application must include a document which outlines in one short paragraph your expertise in translation control, deep sequencing/high throughput methodologies and mammalian cell culture and how it will enhance the particular research activities outlined in the advert.

For full details of this post and to complete an online application, visit https://mrc.tal.net/vx/lang-en-GB/appcentre-1/candidate/postings/419 and upload your CV along with a covering letter. Please quote reference TOX 390.

The MRC is an Equal Opportunities Employer.
Final appointments will be subject to pre-employment screening.
7017| Center for NanoScience Munich| Biophysics at TU Mnich: Self Organization in Cytoskeletal in vitro Systems| Project: Living cells rely on the constant supply of energy, and their unique ability to self organize functionalities relies on its active nature. In our group we are interested in the self organization of cytoskeletal structures and aim for the reconstitution of functional modules which leads ultimately to dynamic reorganization of its constituents. To this end we apply a bottom-up approach where we control the complexity of our in vitro model systems using purified protein components. In your project, we aim for the reconstitution of active actin networks in vesicles, where the treadmilling dynamics of actin is harnessed to induce dynamic reorganization of the lipid membrane. The interaction with other cytoskeletal systems will also be of interest and one ultimate goal is to also reconstitute these interaction. The project is embedded in the Center for NanoScience Munich (CeNS) and the Opens external link in new windowCollaborative Research Center SFB 863.

Requirements: We are looking for an enthusiastic and creative researcher who has completed a PhD in either biophysics, biochemistry, bioengineering, molecular cell biology, or a related field. Profound experience with experimental lab work is required.

Group: Prof. Dr. Andreas Bausch, biophysics group, physics department, TUM Garching

Start: May 1, 2017 or sooner
6964| University of Leeds, Faculty of Biological Sciences, School of Molecular and Cellular Biology| Research Fellow in Proteostasis Research| Latest start date 1 March 2017, fixed term for 3 years

Project Title: Unravelling the mechanism of transcellular chaperone signalling in C. elegans

We are looking for a highly motivated postdoctoral research fellow – funded by the NC3R - to investigate transcellular chaperone signalling in C. elegans and its role in the protection of neurodegenerative protein misfolding diseases.

Our research in C. elegans has shown that alterations of the expression level of major molecular chaperones in specific tissues, leads to a compensatory up-regulation of cyto-protective hsp90 and hsp70 molecular chaperones in other tissues of the organism. This process of inter-tissue communication is known as Transcellular Chaperone Signalling (TCS) and has the potential to improve the health of a tissue affected by conformational protein-folding diseases associated with old age, including Alzheimer’s and Parkinson’s Disease.

You will be based in the laboratory of Dr. Patricija van Oosten-Hawle at the University of Leeds and work in an interactive and collaborative environment that includes a consortium of bioinformaticians (Leeds Omics) and the Astbury Centre. You should have a PhD (or be close to completion) in Molecular Biology, Cell Biology or Genetics or a related discipline. You will also have experience of using either C. elegans as a model system or Next Generation Sequencing techniques (RNA-Seq, ChIP-Seq).


University Grade 7 (£32,004 – £38,183 p.a.) Due to funding limitations it is unlikely an appointment will be made above £32,004 p.a.

Informal enquiries may be made to Dr. Patricija van Oosten-Hawle, tel +44 (0)113 3430090, email [email protected]

Closing Date: 14 December 2016
Interviews are expected to be held in early January 2017

Ref: FBSMB1090

Click here for further information about working at the University of Leeds www.leeds.ac.uk/info/20025/university_jobs
7020| University of Cape Town, Department of Chemical Engineering| POSTDOCTORAL FELLOWSHIP IN REACTOR DESIGN FOR HYDROGEN FUEL PROCESSING| The Centre for Catalysis Research at the University of Cape Town invites applications for a Postdoctoral Research Fellowship for research in the area of catalysis and, more specifically, reactor design for fuel processing in the fuel to hydrogen programme of its HySA/Catalysis Competence Centre.

The research is intended to develop industry-class know-how in specific aspects of fuel processor reactor design and demonstration with emphasis on the design for local manufacturing, efficient heat integration and laboratory demonstration of prototype LPG fuel processors. The successful candidate will be encouraged to conduct his/her own self-initiated research during the tenure of the Fellowship, supervised by Prof. Jack Fletcher, and consistent with the goals of the fuel to hydrogen team led by the Key Technology Specialist in this field, Mr Niels Luchters.

The Fellowship is valued at R300,000 (Three Hundred Thousand Rand) per annum. No benefits are attached to the Fellowship and no service is required in return for the award. The fellowship is compliant with the SARS policies/rules and is therefore exempt from taxation

The tenure of the Fellowship is ONE year, renewable for up to a further one year, contingent on satisfactory academic progress and on the availability of funds. The successful candidate will be expected to commence the fellowship as soon as possible.

Conditions of Award:
• Applicants must hold a PhD in Chemical Engineering or related engineering fields, (granted within the past 5 years or the candidate must provide satisfactory evidence that the PhD thesis has been submitted for examination) within the field of heterogeneous catalysis and fuel to hydrogen,
• The applicant must have experience in fuel processor designs and operation,
• The applicant must not have previously held any permanent professional or academic positions,
• As part of the successful candidate’s professional development, limited supervision of postgraduate students may be required,
• The successful incumbent must be prepared to comply with the University’s approved policies, procedures and practices of the postdoctoral sector. The fellow must not be registered for any degree studies while he/she holds the fellowship.

Application Procedure:
Applicants should submit the following documents:
• A letter of application, in which the applicant’s research interests are outlined, and in which evidence of the required experience is provided,
• All academic transcripts (no certificates),
• A CV including details of all publications (journal and conference),
• Letters of reference from two senior research staff/academics who have supervised/taught the applicant.
Only eligible and complete applications will be considered. Complete applications must be submitted to Niels Luchters by email to [email protected], no later than 13 December 2016.

The University of Cape Town reserves the right to disqualify ineligible, incomplete and/or inappropriate applications, to change the conditions of award or to make no awards at all.
1037814| NeoDiagnostix| Clinical Laboratory Scientist| Clinical Lab Scientist will be responsible for development, validation and performing of clinical laboratory tests and assays in accordance with established policies, procedures and regulations in the NeoDiagnostix CLIA laboratory, including interpreting results. Additional responsibilities include research and clinical development of diagnostic tests along with preparation of data presentations and manuscripts.

The Clinical Laboratory Scientist must:
· Assist Laboratory Director and Medical Director in operation of clinical diagnostic laboratory
· Assist in developing and establishing policies and procedures for the laboratory
· Performs and interprets results of clinical laboratory tests
· Develops, improves and validates molecular diagnostic tests
· Contribute to ongoing R&D projects
· Contribute to the development of scientific manuscripts and data presentation
· Work in a dynamic, collaborative scientific environment

Education/Experience Requirements:
· Minimum of BS degree in laboratory science or related field
· Minimum 4 years (MS) or 2 years (PhD) in a clinical or research setting is preferred
· Experience in Cytogenetics/FISH is a plus
· Knowledge of CLIA regulations and Clinical Laboratory QA/QC procedures is a plus

Position requires ability to cohesively with the other members of the clinical laboratory work independently within SOP framework, communicate clearly, prioritize and manage multiple projects simultaneously. Basic computer and database management skills are necessary.
About the Company
NeoDiagnostix is an oncology diagnostics company offering clinically valuable genomic tests that improve patient care. The company's flagship product is the Cervical DNA Dtex® test which is utilized by clinicians to guide personalized care decisions for women considered to be at high-risk of cervical cancer.
6998| University of Liverpool, Department of Cellular and Molecular Physiology| Postdoctoral Research Associate Grade 7| We are seeking an enthusiastic, dedicated individual to join a highly motivated cancer cell biology research team. Research will focus on roles of the cancer associated deubiquitylating enzyme BAP1, progressing novel discoveries on fundamental mechanisms into translational research. You should have a PhD in a relevant discipline with evidence of a productive research career. You will have expertise in a broad range of cell biology, protein analysis and molecular techniques. Experience in proteomics, transcriptomics, cancer models, drug responses, immunohistochemistry or statistics is desirable. The post is available from 1 March 2017 for 3 years.

Job Ref: 003765/FPD Closing Date: 4 January 2017

For full details and to apply online, please visit: https://recruit.liverpool.ac.uk
1037841| Michael Bailey Associates - Eindhoven| Your available: Project leader Lithography.112844|

For one of the major research institutions, we are looking for a Project Leader (Lithography).

Start date: January 2017

Duration: 1 year (with possibility to extension)

Location: Leuven, Belgium

Language: English

Project leader

Job Mission

As project leader you will be a key player in making the performance of scanners meet customers demands. You will be responsible for planning and executing projects to produce wafers and data required ensuring device performance.

Job Description

Our end-customers make computer chips. To do so successfully the scanners need to control the process in a very tight window. This window is impacted by the traditional scanner knobs as dose, focus and overlay, but also by the other processes like etch deposition and CMP.

You will combine different expertise inputs from our client to build a process to produce wafers that will meet the requirements of our customer. You will need to link the data and fingerprints to the different steps of the processes and meet the specifications required. You will define a methodology to describe accurately the source and the main contributor for process variations. You will create a documentation to release processes to the production line.

You will be part of a group of people in an international environment with similar competencies, working together to lift their know-how to new levels year-after-year, making sure to be prepared for challenges ahead. You will also be part of a project team, working to meet a shared goal against challenging constraints. Making test plans, carrying out analyses, reporting results, conclusions and recommendations. Interface with other projects and the customer.


A solid technical background (BSc/MSc/PhD in Physics, Optics, Nano Technology, or related)


Some experience in the semiconductor industry, preferably in lithography, is a plus.

Personal Skills

  • Robust personality is a must
  • Strong pragmatic attitude with an analytical view.
  • Self-propelling with a lot of initiative and drive. Able to initiate, influence, stir.
  • Out-of-the-box thinker.
  • Team player, responsible and reliable.
  • Able to distinguish main matters from side issues.
  • Excellent communicator. Knows how to convey complex topics in an understandable fashion.
  • Convincing, speaks up.
  • Flexible and committed.

Michael Bailey International is acting as an Employment Business in relation to this vacancy.

6954| Imperial College London| Research Associate| Imperial College London

Faculty of Natural Sciences

Department of Life Sciences

Research Associate

Salary: £36,070 - £43,350 per annum (maximum starting salary £36,070)

The Department of Life Sciences was the top ranked university department in the UK for research intensity in Biological Sciences in REF2014 (Times Higher Education), scoring 100% on our environment.

We are seeking to appoint a Research Associate to join a world-leading research group at the intersection of synthetic biology, genomics and the area-wide genetic control of harmful insects. You will join the laboratory of Dr. Nikolai Windbichler, based at the South Kensington Campus of Imperial College London (http://windbichler.openwetware.org/).

Our goal is to develop innovative genetic approaches for the control of vectors of human diseases such as Malaria or Zika or insect agricultural pests threatening food production. Our research involves the use of cutting-edge molecular biology and genetics to understand and ultimately control harmful insects and we often employ Drosophila as a testbed for particular concepts. One current focus is on the engineering of synthetic genetic elements causing sex-ratio distortion or exhibiting “gene drive” and hence allow to control insect populations. This involves the use of CRISPR/Cas9 genome editing for the genetic manipulation of insects such as Anopheles gambiae, Aedes albopictus or Ceratitis capitata. The successful candidate will design synthetic DNA constructs and test their performance in transgenic insects. The role will involve a high degree of teamwork and interdisciplinary research as the project is part of a wider collaborative network.

We seek a highly motivated individual to fill this post, in possession of a PhD (or equivalent) in Biology or a related subject and a high level of expertise and skills in molecular biology and genetics. Knowledge of research methods and statistical procedures, and practical experience within a research environment and/or publication in relevant and refereed journals are essential. Additionally, you must have demonstrable experience of working with fruit flies, mosquitoes or other insects. The ideal candidate will also have experience in CRISPR/Cas9 genome editing as well as familiarity with analysis of genomics data and proven experience of managing technical staff.
Excellent verbal and written communication skills, and the ability to write clearly and succinctly for publication are essential. You must be a highly motivated individual, with the ability to develop and apply new concepts, and a creative and proactive approach to problem solving. You must be able to organise and prioritise your own work with minimal supervision and to independently drive forward your research project.

This is a full-time, fixed-term position available for up to two years.

Any candidate who has not been yet been awarded their PhD, will be appointed as a Research Assistant within the salary range £31,740 - £33,370 per annum.

For informal enquiries please contact Dr Nikolai Windbichler: [email protected]

Our preferred method of application is online via our website http://www3.imperial.ac.uk/employment (please select "Job Search" then enter the job title or vacancy reference number including spaces NS 2016 230 PB into "Keywords"). Please complete and upload an application form as directed.

Should you have any queries regarding the application procedure please contact: DoLS Recruitment via e-mail: [email protected]

Closing date: 13 December 2016

Committed to equality and valuing diversity. We are also an Athena SWAN Silver Award winner, a Stonewall Diversity Champion, a Two Ticks Employer and are working in partnership with GIRES to promote respect for trans people.
6983| Royal College of Surgeons in Ireland RCSI, School of Pharmacy| Postdoctoral Researcher| Tenure: Specified Purpose Contract (1 year)
Reporting to: Professor Paul Gallagher / Dr Gráinne Cousins

The Royal College of Surgeons in Ireland (RCSI) is a private, self-financing, not-for-profit medical and surgical college headquartered in Dublin (Ireland) with global reach through its overseas medical universities and health care centres in the Middle East, the Far East and Africa. Since its foundation in 1784, it has played a leadership role in Irish surgical and medical education. Currently, it operates the largest Medical School in Ireland and provides undergraduate education in Physiotherapy, Pharmacy, and Nursing. In addition to Surgery, it also provides postgraduate training and education in Radiology, Dentistry, Nursing & Midwifery, Sports and Exercise Medicine, Healthcare Management and Leadership, and has an Institute of Research.

RCSI recognises that excellence in research is critical to the quality of its educational activities, its credibility, and, overall, to its mission to enhance human health. Recently, RCSI has implemented a new research strategy that will build upon its strength in translational biomedical and clinical research to deliver transformational, high impact changes in health care. Targeting both Irish national and EU funding, along with increased collaboration with industry, is a major part of the RCSI research strategy. Forging increased collaboration between RCSI PIs and industry is of critical importance to achieving success in this area. More information on RCSI Research can be viewed here: http://rcsi.ie/research

The School of Pharmacy at RCSI is part of the Faculty of Medicine and Health Sciences. It is situated on St Stephens Green, in the heart of Dublin, one of the friendliest cities in the world. The School is recognised for its innovation in teaching and research, and attracts both high-quality staff and well-qualified students. More information about the School of Pharmacy at RCSI can be found here: http://rcsi.ie/school_pharmacy

Older adults are susceptible to adverse effects from the concomitant use of medications and alcohol. As the proportion and age of the older population continues to increase, the absolute number using alcohol interactive (AI) medications will also increase. The research group of Dr Gráinne Cousins at the RCSI School of Pharmacy have developed an explicit list of potentially serious drug-alcohol interactions in older adults. We are searching for a highly motivated post-doctoral researcher to lead on a national cohort study evaluating the derived list of potentially serious drug-alcohol interactions. The successful candidate will be based in the School of Pharmacy in the RCSI, and will join a team of pre- and post-doctoral researchers. This post will afford opportunities for participation in delivery of educational and assessment activities as part of support to build curriculum vitae, and the opportunity to travel to disseminate findings.

Specifically the duties of the post will include

Position specification
• Develop a national cohort of community dwelling older adults
• Perform data linkage of patient questionnaires and pharmacy dispensing records
• Ensure accuracy and consistency of all processes
• Manage data, run analyses and critically review results
• Present regular progress reports to the multidisciplinary research team
• Draft reports and manuscripts and other forms of dissemination
• Perform such other duties as may be required from time to time

Person Specification:
The successful candidate should be able to demonstrate the following:
• A PhD (or equivalent research experience) in epidemiology, pharmacoepidemiology, biostatistics or related subject
• Proven ability to perform statistical analyses, experience analysing cohort data is desirable
• Prior experience working with large datasets and evidence of peer-reviewed publications
• Good communication skills
• Ability to take direction and meet deadlines
• Strong organisational and administrative skills with the ability to prioritise objectives
• The ability to work on one’s own initiative as well as in a team environment
• Can operate flexibility within a busy environment; can shift focus when required
• Willingness to undertake training and career development

Application Process:
Please apply online with your CV and Covering Letter no later than 11.30pm on the closing date

Informal Enquiries can be directed to Dr. Gráinne Cousins: [email protected]
7009| LMU Munich, Center for NanoScience| LMU Munich: Designer-Cellulosomes by Single Molecule Cut & Paste| Highly motivated candidates with training in physics, physical chemistry, biophysics or bioengineering are invited to apply.

Project: Biofuel from wood and waste will be a substantial share of our future energy mix and contribute to our organic precursor resources. The hydrocarbons in these materials are tightly packed by lignin. The conversion of lignocellulose to fermentable polysaccharides is the current bottleneck. Up to now, only cellulosomes, the multi-enzyme organelles of bacteria, and certain fungi are capable of breaking down the lignocellulose complexes under ambient conditions; industrial conversion requires harsh and environmentally questionable steps.

In an ERC Advanced Grant project we use single molecule cut and paste technology to assemble large libraries of different designer cellulosomes on a chip surface and combine enzymes from different species produced by on chip in vitro expression. The ultimate goal of this project is to identify the most productive de nuovo arrangement of natural and man-made constituents, which then may be adapted for large-scale production.

The successful candidate for this open postdoc position will further expand this research towards protein modification/engineering, in vitro expression in micro-fluidics devices and long range single molecule cut & paste assembly.

The contract will initially be limited to 2 years with the possibility for further extension. Salary is in accordance with the German state regulated public service salary scale TV-L 13. The position will be available in autumn 2017 at the earliest.

Further reading:

Mapping Mechanical Force Propagation through Biomolecular Complexes Schoeler et al. Nano Lett., doi:10.1021/acs.nanolett.5b02727

Ultrastable cellulosome-adhesion complex tightens under load Schoeler et al. Nature Communications,doi:10.1038/ncomms6635

From genes to protein mechanics on a chip Otten et al. Nature Methods, doi:10.1038/nmeth.3099

Quantifying Synergy, Thermostability, and Targeting of Cellulolytic Enzymes and Cellulosomes with Polymerization-Based Amplification Malinowska et al. Anal. Chem.; doi:10.1021/acs.analchem.5b00936

Link to PDFs: www.biophysik.physik.uni-muenchen.de/publications/index.html

For further reading about cellulosomes see our partners website: http://www.weizmann.ac.il/Biomolecular_Sciences/Bayer/
6987| Keele University, Faculty of Medicine and Health Sciences| Research Associate| Fixed Term until 31st January 2020

A postdoctoral position funded by the Engineering and Physical Sciences Research Council (EPSRC) is available to work on the project entitled “Combined Magneto-Optical and Fluorescence Lifetime Imaging Microscopy: Towards Cellular Level Magnetic Hyperthermia”, in the Institute for Science and Technology in Medicine (ISTM). This post represents an exciting opportunity for a highly motivated candidate to carry out ground breaking research in the application of magnetic nanotechnology to cancer therapy. The aim of the project is to understand the magnetisation dynamics that govern cellular-level magnetic hyperthermia, and thus how the effect can be optimised as a mechanism for targeted cancer cell destruction.

The project is in collaboration with the School of Physics, University of Exeter. The group will develop prototype versions of a novel magneto-optical microscope that will be used to measure the local magnetisation dynamics of nanoparticles in cells and tissues.

You will explore how magnetic nanoparticle design and environmental conditions affect magnetisation dynamics. You will also help with the development and evaluation of the magneto-optical microscope, and the integration of fluorescence lifetime imaging microscopy (FLIM) methods as a mechanism for combined measurement of local magnetisation and heating response. Building on this, you will study the in situ behaviour of magnetic nanoparticles in cell cultures, tumour sections, and synthetic tissue-engineered tumour models.

You will form part of an interdisciplinary team with expertise spanning magnetic nanotechnology, magneto-optical techniques, tissue engineering, and oncology. In addition to collaborating with the group at Exeter, you will also spend time working in the laboratories of our project partners in Madrid, IMDEA Nanoscience, learning how to prepare and characterise bespoke magnetic nanoparticles for use in the project.

You must have a strong Physical Sciences background, preferably including work with nanoscale magnetic materials, and have a keen interest in applying this expertise to biomedicine. Experience of fluorescence microscopy techniques and/or cell culture work would be an advantage. You must be able to evidence academic performance with a good publication record, excellent writing and communication skills and a commitment to work on scientifically challenging problems. You should have a PhD in Physics or BioPhysics, Biomedical or Materials Engineering or a related discipline, or have submitted your PhD thesis by 1st January 2017.

You will enjoy access to high level facilities and instrumentation available at the ISTM. Approximately 90% of ISTM's research was rated as world leading or internationally excellent in the most recent Research Excellence Framework assessment (REF2014). ISTM specialises in translational research and REF2014 results demonstrate that the research carried out at ISTM has genuine impact on the world around us. Further information can be found at https://www.keele.ac.uk/istm/

For informal enquiries, please contact Dr Neil Telling, email: [email protected]

Keele University is committed to the principles of the Athena SWAN charter, and values equality and diversity across our workforce. We strive to ensure that our workforce is representative of broader society, and therefore, we would actively welcome applications from women for this role.

Please note this appointment is subject to medical clearance and ongoing medical surveillance by the University Occupational Health provider.

Post Ref: KU00000309
For full post details please visit: www.keele.ac.uk/vacancies

Keele University employees wishing to apply should login to Employee Self Service and click on the 'View current vacancies' link.

Closing date for applications: 20 December 2016.
Interviews will be held on: Early January 2017.
Promoting Equality, Valuing Diversity.
6986| Baylor Scott & White| Assistant & Associate Investigator/Professors: Cancer Genetics, Epigenetics and Biomarkers| Assistant & Associate Investigator/Professors: Cancer Genetics, Epigenetics and Biomarkers
Baylor Scott & White
Dallas, TX

Multiple Investigator/Professor positions are available for immediate recruitment for highly motivated candidates to join a team of researchers at the Baylor Scott & White Research Institute and Charles A Sammons Cancer Center, Dallas, TX, USA.

Research Description:
The laboratory headed by Ajay Goel, PhD focuses on understanding the interplay between genetic and epigenetic alterations in colorectal, pancreatic, gastric and esophageal cancers. We are a multidisciplinary research group, undertaking a number of collaborative projects involving large international consortia. The projects will involve any/all of the following research focuses.

Exploration of the role of aberrant DNA methylation, histone modifications and non-coding RNAs (miRNA, lncRNAs, snoRNAs, piRNAs etc.) in gastrointestinal cancers.
Establishment of innovative methodologies for the development of epigenetic and non-coding RNAs-based biomarkers for the earlier diagnosis, prognosis and predictive responses to chemotherapy in gastrointestinal neoplasia.
A better understanding of the translational and clinical role of genetic and epigenetic signatures in gastrointestinal cancers.
Understanding the genetic basis of early-onset and familial colorectal cancers.
Chemoprevention of gastrointestinal cancers using dietary nutraceuticals, non-steroidal anti-inflammatory drugs (NSAIDs), and other drugs.
Molecular mechanisms of cancer chemotherapy, stem cells, chemo-resistance and chemo-sensitization.
Gut microbiome, and its influence on gastrointestinal cancers.

Additional information on our research is available at: http://www.baylorhealth.edu/GiResearch

Job Description:
An ideal candidate should have a strong background in biochemistry and/or molecular biology, and relevant experience in cancer genetics and epigenetics. The candidates with prior hands-on experience in sequencing-based platforms (Ion Torrent PGM sequencer, MiSeq/HiSeq, RRBS, ChIP-Seq, MeDip and RNASeq etc.) and other array-based platforms will be given preference.

The Investigator/Professor heads a laboratory that focuses its research in an area that is compatible with goals of the Baylor Scott & White Research Institute and meets the approval of the Center Director. They are responsible for hiring, training and management of their lab personnel and for assuring that they work according to the Baylor Scott & White Research standards. While the Investigator/Professor may receive supplemental funds from Baylor Scott & White Research, it is the Investigator’s responsibility to obtain grants that will support their research and to produce data that is worthy of publication in leading scientific journals and has patent potential. The Investigator/Professor is a member of the Baylor Scott & White Research faculty and plays a role in the continued growth and development of Baylor Scott & White Research Institute. He/she may be asked to serve on committees, develop collaborations or act as a liaison with external departments.

The Assistant Investigator/Professor is an entry-level position for an individual who will pursue a career track as a self-sustaining Scientist. An Assistant Investigator/Professor may be promoted to the level of Associate Investigator/Professor once they have obtained multiple grants of a specified nature.

The Associate Investigator/Professor is a high-level position for an individual who is a self-sustaining Scientist and has achieved recognition in his/her field of endeavor. An Associate Investigator/Professor may be promoted to the level of Investigator once he/she has obtained multiple grants of a specified nature and/or achieved recognition as a leader in his/her field.


Minimum Requirements: The candidate should possess the following criteria:
1) PhD and/or MD/PhD
2) Evidence of first author peer-reviewed publications and prior grant funding success
3) Prior molecular and/or cancer biology experience and evidence of project development
4) Excellent organizational, communication and writing skills.
5) Prospective candidates should be highly motivated, enthusiastic about science, with an
ability to think creatively and independently and in a team environment.

To Apply: Interested candidates should submit a CV and cover letter summarizing your Qualifications, Research Interests and Career Goals, and describe your specific interest in our lab. Include the names and contact information of 3 references. Submit applications to:
Ajay Goel, Ph.D. - [email protected]

Join Baylor Scott & White Health
Baylor Health Care System, based in Dallas, and Scott & White Healthcare, based in Temple, Texas, have formed a new organization that combines the strengths of their two nationally recognized health systems. For an industry undergoing fundamental changes, Baylor Scott & White Health provides a new vision and more resources, offering patients continued exceptional care. Baylor Scott & White Health includes 43 hospitals, more than 500 patient care sites, more than 6,000 affiliated physicians, 34,000 employees and the Scott & White health plan.

Baylor Scott & White Health is an Equal Employment Opportunity employer that values the strength diversity brings to the workplace. Baylor does not accept unsolicited resumes sent by or on behalf of a third party agency or firm. Baylor Scott & White Health will not pay fees to any third party agency or firm that does not have a signed “Baylor Scott & White Health" Agency Fee Agreement.

Skin Research Group


Molecular mechanisms in atopic eczema

Grade 7 (£31,076 - £33,943 per annum, dependent on experience) / Grade 7 Training (£27,629 - £30,175 for candidates who have submitted their PhD thesis and await viva examination)

Applications are invited for a postdoctoral research position in the laboratory of Professor Sara Brown, a Wellcome Trust Senior Research Fellow in Clinical Science, to study the molecular and cellular mechanisms in atopic skin and eczema.

Atopic eczema is an itchy inflammatory skin disease which can have a huge impact on the quality of life of an affected individual. Atopic eczema is a complex trait, arising from the interaction of multiple genetic and multiple environmental factors. However, the disease is strongly heritable, emphasising the predominant role of genetic factors and the prime motivation of Sara’s research is to understand the molecular genetic mechanisms with the aim of using this knowledge to develop new and more targeted treatments.

Genome-wide studies have identified loci associated with eczema risk but the genes and mechanisms involved remain largely undefined, a challenge that is shared with other common complex traits. Our approach to address this question uses a skin organotypic model, in which candidate genes can be knocked down or over-expressed and the resultant effect analysed using methods of histological, molecular and functional assessment. Research within the University of Dundee allows access to world-class facilities and expertise in microscopy, molecular genetics and proteomics. A parallel approach to understand genetic mechanisms in eczema is to apply ultra-deep next generation sequencing and bioinformatic analysis to study the role of copy number variation in genes responsible for epidermal differentiation. This analytical work will require laboratory follow-up with conventional assays and application in population-based eczema studies for which large clinical sample sets are available.

We are looking for an ambitious and highly motivated Postdoctoral Researcher to join our team, to be supported by Sara’s Wellcome Trust Senior Research Fellowship. Prior experience of relevant molecular genetic, cell culture, basic microscopy and proteomic techniques would be advantageous, as well as evidence of ability to work both independently and as part of a multidisciplinary team. Evidence of publication within the field of molecular genetic mechanisms is also desirable.

The University of Dundee is a leading institution for biomedical research and offers a vibrant research environment with world-leading facilities; it is recognised internationally as a centre of excellence for skin genetic research. The School of Medicine is focused on understanding and combating disease and was given the top rating for its clinical impact at REF2014, which included Sara’s on-going work on the role of filaggrin in atopic disease.

This position is available for 12 months in the first instance and may become available for a longer period, subject to on-going funding.

Interview Date 12 January 2017

For details of the Brown lab please see https://medicine.dundee.ac.uk/staff-member/professor-sara-brown

For informal enquiries, please contact Prof Sara Brown on 01382 383210 or [email protected]

The University of Dundee is committed to equal opportunities and welcomes applications from all sections of the community.

The University of Dundee is a Scottish Registered Charity, No. SC015096
1037818| Provide Consulting Ltd| 3d Printing Specialist|

3D Printing Specialist

An innovative technology development consultancy within the Cambridge technology cluster are looking to expand! Their Print Technology Division combines deep expertise in optics, microfluidics and printhead physics with a broad digital printing systems integration capability. They invent and deliver print technology and printing systems across a range of applications, and see massive potential in next-generation 3D printing technology; their work is funded by corporate and startup customers who share that view.

I am looking for future leaders: technologists who are equally at home doing cutting edge technology development in labs, or enthusing our customers and uncovering new opportunities

* A PhD or first/upper-second class BSc in a related scientific or engineering discipline
* A proven ability to analyse, deconstruct and solve complex problems, and multi-faceted design challenges
* Experience in the design and development of digital printing, microfluidics or additive manufacturing technology
* An opportunity spotter: curious, imaginative, and commercially astute
* Already successfully leading a team, or ready to do so
* Strong communication and influencing skills, ideally proven in a consulting or customer-facing role
* Ambitious and self-starting, with a desire to combine both technical and commercial insight to create business impact

In return you will receive a highly competitive salary and benefits package, excellent career progression and training as well as relocation assistance if required. You can expect huge day-to-day variety in your work, and will be involved in multiple projects from different industry sectors. Career development is accelerated through a process tailored to the individual, but which typically includes a blend of on-the-job mentoring, bespoke internal courses, and externally provided training.

6994| University College London, UCL Biochemical Engineering| Research Associate in Mixing and Scale-Down| The appointment will be full time on UCL Grade 7. The salary range will be £34,056 - £41,163 per annum, inclusive of London Allowance.

A new 12 month Research Associate position in Mixing and Scale-Down is now available. The position, based initially in Biochemical Engineering at UCL, will address the integration of technologies to optimise scale-up at the partner’s industrial site. There will be a high degree of interaction with UCL colleagues and industrial partners so excellent team-working and communication skills will be required. The post holder will be responsible for undertaking original experimental research, reporting on project progress and the preparation and submission of research papers arising from these and related studies.

The project focuses on understanding the engineering fundamentals and mixing underpinning a conjugate vaccine manufacturing process aiming to validate scale-down approaches for vaccine production. The project is funded by Pfizer Inc.

UCL is one of the leading international centres for engineering fundamentals and fluid dynamic characterization applied to bioprocessing. It has excellent research facilities including a new bioprocessing suite of vaccines-dedicated laboratories and a full-scale £25m bioprocessing pilot plant. The post-holder will be part of a team of research associates and PhD students with expertise in mixing and experimental fluid dynamics led by Dr Martina Micheletti.

Hold a PhD in a relevant discipline (Bio/Chemical Engineering, Biotechnology, Mechanical Engineering or Bioengineering) and ideally possess experience in one or more of the following areas: mixing, fluid dynamics, vaccine process design, scale-up, rheology.

For further details about the vacancy and how to apply online please go to http://www.ucl.ac.uk/hr/jobs/ and search on Reference Number 1608321.

If you have any queries regarding the application process, please contact Dr Martina Micheletti ( [email protected] ).

Closing Date: 3rd January 2017.

Latest time for the submission of applications: 23:59.

Interview Date: TBC.

UCL Taking Action for Equality
7016| Umea University, Department of Molecular Biology| Postdoctoral fellowship in studies of diversification of antibodies (2 years)| Umeå University is dedicated to providing creative environments for learning and work. We offer a wide variety of courses and programmes, world leading research, and excellent innovation and collaboration opportunities. More than 4 300 employees and over 30 000 students have already chosen Umeå University. We welcome your application!
We offer a fellowship for postdoctoral research in our laboratory at the Department of Molecular Biology, Umeå University, Sweden. The department is the host of Molecular Infection Medicine Sweden (MIMS), a partnership of EMBL (http://www.mims.umu.se/). The ability of lymphocytes to generate enormous repertoires of antigen receptors that tag pathogens for elimination plays a major role in protecting higher organisms from infections. However, defects in the antibody diversification processes are also associated with tumour development and with development of many other diseases. We are interested in understanding the detailed mechanisms of the antibody diversification processes in the immune system. The candidate will participate in a project with the aim to analyse the regulation of antibody diversification, somatic hypermutation and class switching of antibodies, and the roles of inhibition of the transcription factor E2A by the Ca2+ sensor protein calmodulin in these processes. The studies expand to experiments addressing that Ca2+/calmodulin inhibition of E2A plays a major role in the regulation of antibody diversification and many other key steps in B lymphocyte development. The work will include analysis of the regulation of the expression levels of components in antibody diversification, analysis of the interactions of the proteins by proximity ligation assays, ChIP sequencing and other techniques, sorting of B cells, FACS analysis, microscopy techniques, and analysis of interactions and collaborations of proteins in antibody diversification.
Successful candidates should have received a Ph.D. degree in immunology, cell biology, molecular biology, biochemistry, genetics or a related discipline and have experience in fields relevant for the project. We are seeking applicants with extensive laboratory experience in culturing and analysis of eukaryotic cells. It is advantageous if the applicant has documented practical experience in several of the fields of gene expression analysis, protein-interaction analysis, DNA cloning, FACS, cell sorting and microscopy techniques. Applicants with a strong background in protein biochemistry are also encouraged to apply. The candidate is expected to execute his or her project independently but also in close collaboration with the other members of the research group. Good written and oral communication skills in English are essential.

The application for the postdoctoral fellowship should include:
• A cover letter summarizing your research interests and experience, your suitability for the position and motives for applying (maximum one A4 page)
• A CV including publication list and PDF copies of relevant exam certificates
• Names and contact details including e-mail addresses of three academic references
• Other relevant documentation you wish to include in support of your application
Documents sent electronically should be in MS Word or PDF format.

Questions may be addressed to Prof. Thomas Grundström, [email protected], Dept. of Molecular Biology.
Your complete application, marked with reference number FS 2.1.6-2184-16, should be sent to [email protected] (state the reference number as subject) or to the Registrar, Umeå University, SE-901 87 Umeå, Sweden, before January 5, 2017. In case no suitable candidate is found after deadline the fellowship will be available until a successful candidate has been selected.
1037816| SJB Service UK Ltd| Resident Medical Officer - SpR Cardiac Doctor - LONDON| We are recruiting for Resident Medical Officers – Cardiac Doctors equivalent to NHS ST4 and above SPR Registrar level. Permanent contract – Weekly rota of 12 and/or 24 hours shifts. Full and part time contracts available at our award winning Clinic in West London.

Salary dependent upon experience – up to £60000 plus a vast range of benefits

Additional benefits;
•- Funded Study Leave;
•- Guaranteed annual salary review and appraisals;
•- Private Pension;
•- 25 days annual leave (with the option to buy or sell up to five days annual leave)
•- Life Assurance (equivalent to two times your annual salary)
•- HCA Pension Scheme
•- Season ticket loan (of up to the value of £10,000)

We are supportive of training and have developed links with Universities to provide a programme of joint appointments for those doctors wishing to study for a higher degree such as a PhD. We are looking to extend this co operation with NHS facilities and Research Institutes for doctors who also wish to go out of programme to study for other qualifications such as management degrees and diplomas.

As a Resident Medical Officer you will work as Registrar level with clinical duties and will play a vital role in managing the medical care, working closely with Consultants to ensure that patients’ treatment and care needs are met. All patients are admitted under a Consultant who is responsible for management.

Responsible for providing medical cover, routine and emergency during hours of duty. Undertake a daily ward round with a member of the nursing staff and / or Consultant Specialist . Admit and clerk patients, take blood samples as requested, countersign any drug instructions given by the consultants.

Undertake certain routine medical procedures as required such as; venepuncture, setting up an intravenous infusion, inserting a urinary catheter, arterial blood sampling, or ECGs. Take part in ward audits and research to continuous improve and strive for excellence, for staff and patients. Attend Committee, in house training and other relevant meetings as required.

• Management of acute related emergencies. MBBS or equivalent medical qualification
• Fully registered with the GMC and current licence to practice.
• SPR/Registrar Level Cardiac practice experience essential
• Evidence of achievement of Foundation competences from a UKFPO affiliated Foundation Programme
• Evidence of successful completion of CT/ST1&2 training/competences
• Post holder must hold current ALS certificate

To apply, please upload your CV online, email Steve Thorpe at sjb medical, London or call or for further information.
7013| Center for NanoScience Munich, Max Planck Institute of Biochemistry| Postdoc position biophysics/fluorescence microscopy| We seek a Fluorescence Microscopy Expert at the Max-Planck-Institute of Biochemistry (MPIB) in Martinsried (Munich), Department Cellular and Molecular Biophysics (Prof. Dr. Petra Schwille) to strengthen our team for the development of new microscopy-based biophysical methods.

Our group has a strong background in single molecule techniques and is working at the highly interdisciplinary interface of physics, biology and biochemistry.

Requirements: The applicant should have a strong background in optics and method development, especially in the context of cellular and biochemical research. A PhD (or equivalent) in physics or a closely related discipline would support the application. Experience in one or more of the following fields is desirable: fluorescence microscopy and/or spectroscopy, development of optical setups, image and data analysis.

The Max-Planck-Society seeks to increase the number of women in those areas where they are underrepresented and therefore explicitly encourages women to apply. Furthermore, the Max-Planck society is committed to increasing the number of individuals with disabilities in its workforce and therefore encourages applications from such qualified individuals.

About the institute: The Max-Planck-Institute of Biochemistry is a leader in the field of biochemistry, cell- and structural biology, and biomedicine. With seven scientific departments, more than 30 research groups, and a staff of around 850 scientists, the institute is one of the largest within the Max-Planck-Society.

30 paid vacation days. Up to 14 months compensated parental leave possible.

Group: Prof. Petra Schwille, Max Planck Institute for Biochemistry, Munich
7004| University of Derby, College of Life and Natural Sciences| PhD studentship (Graduate Teaching Assistant): Alternative methods for assessing habitat quality in UK waterways| Reference: HabQal16

About the studentship:
Applications are invited for a full-time PhD studentship commencing February/March 2017 or as soon as possible thereafter. The successful applicant will work within the Environmental Sustainability Research Centre at the University of Derby to address a predefined research topic (see details below). The studentship will be granted in the form of a Graduate Teaching Assistantship which means that, alongside your research, you will undertake a limited amount of teaching through which you will contribute to the wider University community and develop skills you need for a successful academic career.

If granted the PhD studentship, subject to the interview process, and following satisfactory progress, you will receive £14,296 p.a. for three years and your fees will be fully covered at a UK/EU level.

About the research topic:
The PhD will explore alternative methods for assessing habitat quality in UK waterways.

Current methods for assessing the quality of waterways (rivers, streams, lakes, reservoirs etc.) require laborious searching from dedicated individuals who need a good knowledge of the taxa they are searching for. In some instances, such knowledge is not sufficient and in many cases certain species often get overlooked. Moreover, surveying by species observation is invasive, causing disturbance, and can cause stress, injury or in some cases fatalities. Designing new methods which are quicker, cheaper and equally or more reliable than previous methods are therefore highly desirable to stakeholders including ecological consultants, developers, governing bodies and researchers alike.

In the UK, and nearly every country in the world, freshwater ecosystems are often the least studied habitat but have suffered major declines in native populations of both invertebrates and vertebrates. Yet if such studies are undertaken, valuable data can be gained for industrial mitigation that affects humans as well as the fate of individual species and the effects overall of the freshwater ecological chain. In addition, these systems host some of the most problematic invasive species including the Zebra mussel (Dreissena polymorpha) and the killer or demon shrimps (Dikerogammarus villosus and D. haemobaphes). The use of environmental DNA (also known as eDNA) is a newly emerging tool available to a growing demographic and offers the potential of vastly improving our detection of both native and invasive species throughout aquatic systems. This PhD aims to explore the use of this technology targeting a variety of invertebrate and vertebrate species throughout the UK. These include the previous examples, along with the Quagga mussel (Dreissena bugensis), the depressed river mussel (Pseudanodonta complanata), the freshwater pearl mussel (Margaritifera margaritifera), the fine lined pea mussel (Pisidium tenuilineatum) and the European eel (Anguilla anguilla). The work will also include aspects of field work whereby the PhD student will optimise the collection methods for each species with a view to getting methodologies adopted by others ensuring that results are consistent across the country.

This work would also underpin a further PhD project aimed at addressing a metagenomics approach in an attempt to cover a more comprehensive group of invertebrates tackling those usually classified in BMWP surveys and potentially expanding to cover invertebrate species especially fish. These new techniques will be validated against a range of existing techniques for surveying freshwater ecosystems.

Further information about the research environment and supervisory package:
You will join an active research group consisting of 6 PhD students and 2 Masters students and be supervised by Drs Michael Sweet and Andrew Ramsey (see details below). You will work closely with two of these PhD students who currently work on eDNA with native and invasive crayfish in the UK and bioremediation of mussels. Your commercial supervisor will be Troy White who is the Laboratory Manager at Surescreen Scientifics. Surescreen Scientifics is part of a medical and forensic company with two facilities in the Derby area, and the Morley site close to Derby, and has forensic, analytical and DNA facilities.

Please see the staff profiles or email the project supervisors for more information related to this project.

Dr Michael Sweet, Senior Lecturer in Invertebrate Biology
Email: [email protected]
Website: http://www.derby.ac.uk/staff/michael-sweet/

Dr Andrew Ramsey, Senior Lecturer in Animal Ecology
Email: [email protected]
Website: http://www.derby.ac.uk/staff/andrew-ramsey/

We are looking for a highly-motivated student who is capable of studying at PhD level and enjoys independent research. Prospective candidates are also expected to have a good Honours degree. An interest in the research topic is essential and a background in any of the following would be useful: molecular ecology, molecular biology, genetics, chemistry/biochemistry, aquatic ecology, freshwater ecology, aquaculture, consultancy.

Please see website for Person Specification and Application requirements.

Informal enquiries may be addressed to Dr Michael Sweet ([email protected]), or Dr Andrew Ramsey ([email protected]). Please note that applications sent directly to these email addresses will not be accepted.
Complete applications should be forwarded to Stuart Wain at [email protected] quoting reference number HabQal16 in the title of your email.

Interviews will be held mid to late January 2017. If you have not been contacted by then please assume that on this occasion you have not been shortlisted for interview.
1037834| Ricerca Biosciences, LLC| Staff Toxicologist|



Study Director for pilot and IND-enabling studies. Experience in chronic, investigative and carcinogenicity study designs. Responsible for the planning, conduct and successful reporting of assigned studies. Participate in report review and generation process. Develop new capabilities for Ricerca Biosciences. Communicate with Sponsors as required.


Participate in the proposal and bid development process

Serve as a key contact for sponsors

Participate in and coordinate all phases of the study planning process with Client Services and technical and laboratory support operations

Responsible for study design and generation of protocols

Interpret study data, write reports and draw conclusions

Develop and foster business relationships

Perform other duties as assigned


PhD in Toxicology or Pharmacology or a related field. Ability to interact with multiple personality types and cultural backgrounds.

DABT preferred.

Working knowledge of Good Laboratory Practices regulations

Attention to detail and excellent interpersonal and communication skills

We offer a competitive wage along with a comprehensive benefit plan.

Ricerca is an equal opportunity employer.


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