The Institute of Cancer Research, London, is one of the world’s most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. We provided the first convincing evidence that DNA damage is the basic cause of cancer, laying the foundation for the now universally accepted idea that cancer is a genetic disease. Today, The Institute of Cancer Research (ICR) leads the world at isolating cancer-related genes and discovering new targeted drugs for personalised cancer treatment.
Under the leadership of our Chief Executive, Professor Paul Workman FMedSci, the ICR is ranked as the UK’s leading academic research centre. Together with our partner The Royal Marsden, we are rated in the top four cancer centres globally.
The ICR is committed to attracting, developing and retaining the best minds in the world to join us in our mission – to make the discoveries that defeat cancer.
We are looking to appoint a Postdoctoral Training Fellow to join the Signalling & Cancer Metabolism Team (led by Dr George Poulogiannis) based in the Division of Cancer Biology at the Institute of Cancer Research, London in Chelsea. Applicants will hold a PhD in Biochemistry, Molecular Biology or a similar discipline and should have a strong background in Signal Transduction research and protein ubiquitination, which is supported by a solid publication record in this field. This post is most suitable to applicants early in their postdoctoral career but candidates in their final year of Ph.D. with a strong publication record (and at least one first authored) are welcome to apply too. As a minimum requirement candidates must have submitted their thesis by the start date of their employment and been awarded their PhD within the six month probationary period.
This is an ideal opportunity for a committed and enthusiastic individual with experience in in vivo and in vitro ubiquitination assays, protein purification, immunoprecipitation and immunoblotting. The research focus of our lab is to understand the signalling and metabolic networks that are related to cell growth and malignant transformation. In line with these efforts, applicants should have experience with mammalian cell culture, transfection, cell proliferation assays, cell migration and invasion assays, cell anchorage-independent growth assays, dual luciferase assay, flow cytometry and fluorescent microscopy. Additional experience in generating in vivo xenograft models and immunohistochemistry are highly desirable. Excellent organisational and communication skills are essential.
The position is available immediately. Starting salary will be in the range of £28,966 - £35,608 p.a. inclusive based on postdoctoral experience and relevance of skills. The appointment will be offered on a fixed term contract of 3 years in the first instance.
Informal enquires can be made to Dr George Poulogiannis at
[email protected]. Please do not send your application to Dr Poulogiannis, formal applications must be submitted online.
To apply please submit your CV and covering letter (addressing where you meet the person specification and incl. the names and addresses of two referees) online at
http://www.icr.ac.uk/jobsearch. Job Reference Number 1451769.
Please include the following with your application:
• A full CV with a publication list (two to three pages)
• Covering letter including the names and contact details of two referees (one page)
• Research plan (one to two pages outlining your current research interests and research plans for the next 3 years)
Closing date: 20th February 2015
