We are looking for a highly motivated candidate with an extensive experience in molecular and cellular biology and who has already performed mouse model studies. Applicants should hold a PhD degree in Biochemistry/Molecular Biology or related disciplines (or have recently submitted their thesis with scheduled defense) and have published (or about to publish) in a peer reviewed journal. Experience in epigenetics/epigenomics would be an asset.
The post-doctoral position will be opened in March 2018 for five years (renewed each year) in the laboratory of research on molecular basis of AcuteMyeloid Leukemia headed by an ERC / ATIP-AVENIR team leader Dr. Alexandre PUISSANT (
https://thepuissantlab.jimdo.com/) . You will be expected to decipher molecular mechanisms involved in leukemia development in pre-clinical mouse models of AML. Unbiased in vivo screening approaches will also be deployed in order to provide new therapeutic strategies to treat AML. Large-scale shRNA screening, genetic, biochemical, cell biological, as well as genome-wide approaches (whole-exome sequencing, RNA-Seq, ChIP-Seq) will be applied.
THE TEAM:
The Puissant laboratory is housed at the Jean Bernard Center (INSERM U944) which is located at the Saint-Louis Hospital campus in Paris, France . The research developed in this institute encompasses a broad spectrum of fields, including cancer genomics, cancer biology and leukemia research. Most studies carried out in the unit have implications in translational research, together with clinical groups of the Saint-Louis Hospital. Our laboratory benefits from a direct access to the core facilities including: a recently extended animal facility, a sequencing facility (Mi-seq, Hi-seq, and Next gen-seq technologies), and a flow core facility.
HOW TO APPLY:
Thanks to send your application (in French or English) to alexandre.puissant(at)inserm.fr before February 1st 2018 , by including in one single pdf file (applicantName_application2018.pdf):
personal statement explaining why the candidate is interested in joining the lab and her/his future expectations in term of career development (max 1 page);
description of the main past achievements and technical skills of the candidate (max 2 pages);
full Curriculum Vitae;
contact details of three individuals who can be contacted for recommendation letters.
