Closing Date of vacancy: 27 Jan 2017
Division: Cancer Therapeutics
Team: Hit Discovery & Structural Design
Type of Contract: Fixed Term
Length of Contract: 12 months
Salary Range: £34,247 to £36,830
Work Location: London and Sutton (Surrey)
Hours per week: 35
The Institute of Cancer Research, London, is one of the world’s most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. We provided the first convincing evidence that DNA damage is the basic cause of cancer, laying the foundation for the now universally accepted idea that cancer is a genetic disease. Today, The Institute of Cancer Research (ICR) leads the world at isolating cancer-related genes and discovering new targeted drugs for personalised cancer treatment.
Under the leadership of our Chief Executive, Professor Paul Workman FMedSci, the ICR is ranked as the UK’s leading academic research centre. Together with our partner The Royal Marsden, we are rated in the top four cancer centres globally.
The ICR is committed to attracting, developing and retaining the best minds in the world to join us in our mission – to make the discoveries that defeat cancer.
The Cancer Research UK Cancer Therapeutics Unit (CTU), embedded within the Division of Cancer Therapeutics, is a multidisciplinary 'bench to bedside' centre, comprising around 160 staff dedicated to the discovery and development of novel therapeutics for the treatment of cancer. The CTU’s exciting goal is to discover high quality drug candidates for validated biological targets and to progress these candidates to clinical trial. All the scientific disciplines are in place to make this possible, including medicinal chemistry, biology, drug metabolism and clinical specialists.
A postdoctoral position is available in Dr Rob van Montfort’s Hit Discovery and Structural Design Team within the CTU. The Post-doc will be involved in high-throughput X-ray crystallography, fragment-based screening and structure-based drug design and will be responsible for crystallisation, structure determination and structural analysis of protein-ligand complexes from one of the CTU’s drug discovery programmes. The successful candidate will also be part of the Division of Structural Biology, in which the crystallographers in Dr van Montfort’s team are embedded, and will have access to state of the art crystallisation facilities, in-house X-ray sources and excellent access to synchrotrons. The successful candidate will interact closely with the biology, computational chemistry and medicinal chemistry teams at the CTU, and will therefore be expected to work across the two sites in Chelsea, London and Sutton, Surrey.
Applicants must have a PhD in a biological or physical science, and experience in macromolecular crystallography (to include protein biochemistry, protein crystallisation, & protein crystallography). Experience in molecular biology, structure-based drug design, and/or biophysics will be an advantage.
The starting salary for the position will be in the range £34,247 to £36,830 p.a. inclusive (based on previous post-doctoral experience) and the post is offered on a fixed term contract of 1 year. Informal enquiries to
[email protected] or
[email protected]. Please DO NOT send your application to Dr van Montfort or Dr LeBihan. Applications must be submitted via the e-recruitment system, accessible via the 'Apply' button.
Further information can be found in the job description please visit
www.icr.ac.uk/careers or click on the apply button below for further details and to apply.
