Postdoctoral Researcher in Genome Maintenance and Diversification Biology

This is an exciting opportunity for a highly-motivated, enthusiastic and ambitious Postdoctoral Scientist to join Professor Ross Chapman at the MRC Weatherall Institute of Molecular Medicine (WIMM).

The Chapman laboratory is world-leading in the study of DNA double-stranded break (DSB) repair systems in immune system development and tumour suppression using molecular and mouse genetics with reductionist molecular cell biology and biochemical approaches. The successful applicant will investigate the origins of haematological and developmental defects that result from cellular DSB repair deficiencies, and their relation to endogenous sources of DNA damage. In addition to working directly with Professor Chapman and his team, the postholder will also work closely with other MRC Molecular Haematology Unit groups; especially Professor KJ Patel’s group, the WIMM FACS, transgenics and genome editing, all based at the WIMM.

You will hold a PhD (or near to completion: thesis submitted) in cancer or genome stability biology, molecular immunology/haematology or allied relevant area. A strong publication record in high-impact peer-reviewed journals (at least two second tier or one first tier first author publication(s)) is a prerequisite, as is the ability to work independently and as part of a team. You will have strong communication and organisational skills, with the ability to manage and independently drive, innovate and complete your own research and associated activities. Experience and/or willingness to work with murine models is essential, and bioinformatics expertise including dataset and coding in “R”, is desirable.

The post is available full time and is fixed-term for 3 years, funded by the Medical Research Council.

Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application.


The closing date for this position is noon on Thursday 24 June 2021.