Post-Doctoral Training Fellow - Structural Biology DNA repair
Structural Biology, The Institute of Cancer Research
We are looking for a talented and enthusiastic post-doctoral training fellow to join the laboratory of Dr. Basil Greber in the Division of Structural Biology at the Institute of Cancer Research (ICR), based in central London. The position will be available from April 2021.
The mechanisms by which cells preserve the integrity of their genomes are critical to our understanding of cancer biology and are a focus of several research groups at the ICR. Dr. Greber’s team at the ICR has been established recently and seeks a post-doctoral research scientist to develop an innovative and multidisciplinary research project to investigate the molecular mechanisms of nucleotide excision repair by combining cryo-electron microscopy (cryo-EM) with biochemical and biophysical methods. Dr. Greber’s previous contributions to the field of nucleotide excision repair include the determination of the complete structure of the human transcription factor IIH (Greber et al., Nature 549, 2017; Greber et al., eLife 8, 2019; Greber et al., PNAS 117, 2020), the centrepiece of this pathway.
We provide a supportive environment and have established collaborations with expert groups within the ICR, in London, and internationally. Successful candidates should enjoy interacting and working with the principal investigator, other team members, and collaborators.
Applicants should possess a PhD in molecular biology, biochemistry, biophysics, or a related discipline and should have acquired prior expertise in the biochemistry of protein-nucleic acid complexes or in structure determination using cryo-EM. Additionally, we expect that the successful candidate has a track record of scientific excellence documented in authorship on published papers (which may include pre-prints).
Please apply on the ICR website by completing the online application form and attaching your CV. Job ref 1228