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Research Fellow

Post title: Research Fellow
School/department: Brighton and Sussex Medical School
Hours: Full time
Contract: fixed term for 36 months
Reference: 4006
Salary: starting at £33,797 to £40,322 per annum
Closing date: 12 August 2020. Applications must be received by midnight of the closing date.
Expected start date: TBC

Applications are invited for a full-time Research Fellow to work in the laboratory of Dr Lisa Mullen at the Brighton and Sussex Medical School on an MRC-funded project to develop a new therapeutic strategy for treating Osteoarthritis using our recently described engineered TIMP-3 to inhibit aggrecanases. The project will involve in vitro and in vivo characterisation of recombinant TIMP-3 to determine how this protein can be engineered for the greatest therapeutic benefit with a focus on protein biochemistry, cell- and tissue-based assays and analyses of tissue by immunohistochemistry and histology.

Applicants for this position should possess an Honours B.Sc (or equivalent) in Biochemistry or a related subject and a Ph.D (or equivalent) in Biochemistry, Recombinant Protein Engineering, Joint Disease or a related subject. Experience of murine models of joint disease and a good working knowledge of a range of methods for analysing ex vivo tissue is essential. Previous experience of relevant laboratory work, Home Office Modules 1-4 and good communication skills are essential, as is the ability to work both independently and as part of a team.

The post is based at the Brighton and Sussex Medical School (BSMS) on the University of Sussex campus. At BSMS, we provide a stimulating and supportive environment with our expertise covering a wide range of experimental systems related to Biomedical Research. Further information about our research can be obtained from our website at http://www.bsms.ac.uk/research/

For informal enquires and for more information, please contact Dr Lisa Mullen ([email protected]).

For full details and how to apply see:

The Universities are committed to equality and valuing diversity, and applications are particularly welcomed from women and black and minority ethnic candidates, who are under-represented in academic posts in science, mathematics, medicine and engineering at Sussex and Brighton.

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