The DNA metabolism laboratory headed by Prof Vincenzo Costanzo invites applications for a three years postdoctoral fellowship in Genome Stability. The DNA metabolism lab has made fundamental contribution to understand the role of BRCA2/RAD51 proteins in DNA replication and replication fork protection against DNA nucleases, a concept that was first established by the Costanzo’s group (Hashimoto et al, NSBM 2010 and Kolinjivadi et al, Mol Cell 2017). More info can be found at: https://www.ifom.eu/en/cancer-research/programs/dna-metabolism.php
The successful applicant will lead a project aimed at understanding the mechanisms of replication fork protection operated by BRCA2 and RAD51 proteins, which are altered in cancer cells. Multiple approaches including DNA electron microscopy, molecular and cellular biology, biochemistry, proteomics and CRISPR based genetic technologies will be used.
IFOM, which is located in the heart of the vibrant and modern city of Milan, provides a highly dynamic, international and collaborative environment to foster scientific breakthroughs.
Applicants must have a recent Ph.D in the field of cell biology, molecular biology, biotechnology or biochemistry and should have the talent and the dedication to take advantage of the vast resources available at IFOM. Experience in one of the following areas is preferred: biochemistry, molecular and cellular biology, DNA and chromatin biology.
The position is grant funded. Salary ranges from 36.000 to 45.000 euro depending on experience.
Potential candidates are requested to send their resume, one page summary of research experience, and names and addresses of two referees to: [email protected]