Starting Salary £30,914 - £33,755 per annum
3 year fixed term
MRC Laboratory of Molecular Biology, Cambridge, UK
We are looking for a computational postdoctoral scientist to join the group of Prof Julian Gough to work on cell fate and evolution. Specifically, to undertake research to investigate human cell reprogramming. We have created a system ‘Mogrify’ based on cellular networks to predict transcription factors for reprogramming one human cell type into another (Rackham et al. Nature Genetics 2016). This has been experimentally validated by proving several novel conversions, and we are validating many more. There is a great deal more research to do on cell reprogramming, e.g. with regard to: epigenetic factors, down-regulation, different sequencing technologies, sources of network interactions and synthetic cell types. The work will be entirely computational.
You are highly motivated, have a PhD in a relevant subject, and you have an aptitude for theoretical work and data analysis. The post is available to applicants with varying computational experience. Applicants with no formal training in computational or mathematical work but who enjoy it, have self-taught to a high level, the aptitude and are keen to learn will be considered, if they have other complimentary biological qualifications, knowledge and experience. Conversely computer or technical scientists with no formal training in molecular biology will be considered if they have a powerful interest and motivation in molecular biology and are driven to learn.
The successful applicant will be awarded a 3 year Career Development Fellowship/MRC Postdoctoral Training Scheme. The fellowship is a training and development position for a Postdoctoral Scientist who has recently completed their doctoral studies, or is moving into a new research discipline. The project will include working with AstraZeneca and other biotech companies internationally and in the Cambridge area to translate the technology for medical use and commercialisation.
Working for the MRC provides a whole host of benefits including a final salary pension scheme, Benenden Healthcare membership and excellent holiday entitlement. You will also have access to employee shopping/travel discounts, on site sport and social facilities, as well as salary sacrifice cycle to work schemes and childcare vouchers.
The MRC Laboratory of Molecular Biology is one of the birthplaces of molecular biology and is an internationally renowned centre for fundamental biomedical research.
The LMB has a strong track record in training Postdoctoral Fellows who have gone on to become leading Scientists. We also have an excellent record of innovative basic research leading to applications in medicine. Scientists are drawn to the LMB from all over the world, thus creating a lively and international community for the exchange of ideas and technical innovation.
For further information of the research undertaken at the LMB, please visit: http://www2.mrc-lmb.cam.ac.uk
Informal enquires may be made to Julian Gough at; [email protected]
The MRC Laboratory of Molecular Biology is a research institute within UK Research and Innovation (UKRI). UKRI is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at www.ukri.org
Working for UKRI MRC provides a whole host of benefits including:
• Defined benefit pension scheme
• Excellent holiday entitlement (40 ½ days including bank holidays & privilege days)
• Benenden Healthcare membership
• Access to employee shopping/travel discounts
• On site sport and social facilities
• Salary sacrifice cycle to work scheme
• Childcare vouchers
To apply and access full details of the vacancy please visit our job board at https://mrc.tal.net/vx/lang-en-GB/appcentre-1/candidate/postings/1285
If you are unable to apply online please contact us at [email protected]
Closing date: 17/09/2019
Final appointments will be subject to a pre-employment screening.
The Medical Research Council is an Equal Opportunities Employer who participates in the Disability Confident scheme.