Postdoctoral Position in Computational Analyses of Chromatin Conformation Dynamics



    The Regulatory Genomics Laboratory at the MPI for Molecular Biomedicine in Münster is offering a:

    Postdoctoral Position in Computational Analyses of Chromatin Conformation Dynamics
    (position code: 03-2019)

    The laboratory seeks to appoint a highly motivated scientist to work on dissecting the molecular mechanisms that regulate chromatin conformation in eukaryotes, which is a strong focus of the group (Hug et al., Cell 2017; Díaz, Kruse et al., Nature Communications 2018). Specifically, the successful candidate will develop and apply computational approaches to investigate the impact of genome organisation in the emergence of disease, with particular emphasis on the analysis of high-throughput sequencing data such as Hi-C, RNA-seq, ChIP-seq, and ATAC-seq. In addition, the candidate will be working closely with wet lab researchers to design experimental approaches based on results of the computational analyses. This position is part of the DFG-funded SPP2202 ‘Spatial Genome Architecture in Development and Disease’ network. The candidate is expected to contribute and benefit from the wide-range of activities organised by the network.

    Requirements
    We are looking for an enthusiastic and talented postdoctoral fellow with a PhD in computational biology, bioinformatics, biostatistics, molecular biology, genetics, epigenomics, computer science, mathematics, or a related field, and with a strong drive to excel in a highly international and collaborative environment. Strong expertise in genomic data analysis (e.g. Hi-C, RNA-seq or ChIP-seq) and proficiency in one or more programming languages (e.g. Python, R) are required. Previous expertise with chromosome conformation capture data analysis (e.g. Hi-C, 4C-seq) is highly desired.

    Terms of employment
    The position is offered initially as a fixed-term appointment for two years with the possibility of further extension following a successful evaluation. The position is available immediately.

    How to apply
    Applications should be sent as a single pdf file by email to [email protected]. The position will be open until filled, but applications received before 15 July 2019 will be considered first. These should include: (i) a cover letter explaining your motivation to join the laboratory; (ii) a full CV; and (iii) the contact details of two academic referees. Please include the position code in your cover letter. Incomplete applications will not be considered. For informal queries and further information please contact Juanma Vaquerizas ([email protected]) or visit www.vaquerizaslab.org.

    About MPI Muenster
    The Max Planck Institute for Molecular Biomedicine offers a highly international and stimulating research environment with state-of-the-art equipment and core facilities for genomics, proteomics and cell biology. The Institute is located in Muenster (http://www.muenster.de/en/), one of the European Green Capitals and former UN’s ‘The World’s Most Liveable City’ awardee. Extra administrative help will be available for foreign scientists. English is the working language in the Institute.

    The Max Planck Society is committed to increasing the number of individuals with disabilities in its workforce and therefore encourages applications from such qualified individuals. Furthermore, the Max Planck Society seeks to increase the number of women in those areas where they are underrepresented and therefore explicitly encourages women to app.

    More details about the Vaquerizas laboratory and the Institute can be found here:
    http://www.vaquerizaslab.org
    https://www.mpi-muenster.mpg.de/79003/institut


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