• European Molecular Biology Laboratory (Heidelberg) Featured Post Docs

Research Fellow - Pathology

  • Application Deadline
    28 May 2019
    (application date has expired)
  • Job Salary
    £40,892 to £49,137 NZD $80,406 - $96,167. Lecturer / Research Fellow
  • Website
  • Contact Name
    Professor Michael Eccles


Who we are:

The Developmental Genetics & Pathology laboratory team is focused on aberrant developmental mechanisms of disease, particularly cancer. The team comprises four research fellows, two assistant research fellows (including a bioinformatician), five postgraduate students, and an intern, housed within a well-equipped research laboratory, and using state-of-the art advanced methodologies. The research team has a well-established international profile.

The Role:

As a Research Fellow based within our department you will be part of the team working on the project ‘Epigenomic profiling to predict patient response to melanoma immunotherapy’.

Some key tasks include:
• Collecting samples for discovery cohorts.
• Carrying out sequencing-based analysis of genome-wide methylation landscapes of responding and non-responding patients.
• Investigating mutational profiles of responding and non-responding patients.
• Developing Sequenom assays for methylation biomarkers identified in responding and non-responding patients.
• Carrying out gene expression analysis of biomarker regions of interest in the validation cohort.
• Contributing to the development and dissemination of research tools for genome-wide and epigenome-wide analysis for the Eccles laboratory group, including for CancerHub.

Your Skills and Experience:

• PhD in relevant field.
• Experience in identifying blood-based biomarkers.
• Experience with epigenetic analysis and large-scale/integrated bioinformatic analysis.
• Organised, methodical, with excellent attention to detail.
• Ability to work as a team member and to interact well with a range of staff and health professionals, and to perform tasks with minimal supervision.

Further Details: Position 1901102

This is a full-time, fixed term position for four years and is available immediately.

Specific enquiries may be directed to Professor Michael Eccles, via the contact details attached.

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