The Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute is an international centre of excellence for stem cell research and regenerative medicine. Scientists in the Institute collaborate to advance our knowledge of various stem cell types and to perform pioneering work in translational research areas, providing the foundation for new medical treatments (https://www.stemcells.cam.ac.uk/
The lab of Dr Joo-Hyeon Lee (https://www.stemcells.cam.ac.uk/research/pis/lee
) studies how multiple different cell types of the lung contribute to homeostasis and injury repair and how they return to quiescent state using in vitro organoids and in vivo mouse models.
We are looking for dedicated post-doctoral researchers to investigate mechanisms that lead to cellular reprogramming and lineage plasticity in lung injury repair and oncogenic events. The lab applies sophisticated genetic mouse models with lineage tracing techniques, mathematical modelling, high-resolution imaging analysis, single cell transcriptomics/ epigenomics/ metabolomics, and ex vivo organoid culture with CRISPR-mediated gene regulation.
Successful applicants should have a PhD in a relevant subject, or be close to completion of their degree. Expertise in general areas of development/stem cell/cancer biology including image analysis, CRISPR genome editing, flow cytometry analysis, and cell signalling mechanisms would be suitable for this position. Experience of murine genetic models and strong background in metabolism and epigenetics would be an advantage. At least one publication with first authorship would be preferable, but not a requirement.
Start date is flexible but can be as early as June 2019.
Fixed-term: The funds for this post are available for 12 months in the first instance.
To apply online for this vacancy and to view further information about the role, please visit: http://www.jobs.cam.ac.uk/job/21005
The closing date for all applications is Tuesday 30 April 2019 with interviews to be confirmed at a later date.
Please ensure that you upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.
Please include details of your referees, including e-mail address and phone number, one of which must be your most recent line manager.
Informal enquiries about the post are also welcome via email on [email protected]
Please quote reference PS18669 on your application and in any correspondence about this vacancy.
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