Post-doc position in phage display, peptide engineering and drug development

Institute of Chemistry and Chemical Engineering, EPFL

Deadline:
30 April 2019
(application date has expired)
£70,000 to £90,000 US dollar
Contact:
Christian Heinis

A post-doc position is available in the group of Prof. Christian Heinis at the EPFL in Lausanne (https://lppt.epfl.ch). The goal of the post-doc project is the development of highly stable cyclic peptides that can be applied orally, which has been a longstanding goal of the pharmaceutical industry. The post-doctoral student will apply a phage display-based technique that was recently developed in the host lab. In brief, large combinatorial libraries of phage-displayed double-bridged peptides will be sequentially subjected to proteolytic sections (to enrich stable peptides) and affinity selections (to isolate peptides binding therapeutic targets). The project involves phage display, in vitro evolution, NGS, automated peptide synthesis, ligand characterization and biological evaluation.

Applicants need to be highly motivated and able to lead a project independently. They should have an education in chemistry, biochemistry or a related subject. Entrance date: May 2019 - September 2019

To apply for the positions, please send a letter of motivation, a CV and a list of references to Prof. Christian Heinis ([email protected]).

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Post-doc position in phage display, peptide engineering and drug development

Institute of Chemistry and Chemical Engineering, EPFL