A POSTDOCTORAL position is available in the laboratory of Dr. Hakem at the Princess Margaret Cancer Centre / University Health Network / University of Toronto, , Toronto, Canada. The Hakem lab’s research program focuses on understanding the mechanisms of cancer and the identification of novel therapeutic strategies for cancer. The lab has excellent track records studying in vivo cancer mechanisms and signaling pathways. These studies include in vivo functions of BRCA1, P53, MUS81, RNF8, RNF168 and CHK2 (Nature Immunol., 1: 77-82; Genes & Dev, 18: 1144-1153; Science, 304: 1822-1826; JEM. 207: 983-97, J Clin Invest. 128: 4525-4542; PNAS 110: 20982-7; Nature Communications, DOI: 10.1038/ncomms 12638). Our studies are based on genetic, proteomic, transcriptomic, bioinformatics, molecular analyses in human cancer cell lines and mouse models, as well as data from cancer patients. Genome-wide CRISPR-Cas9 screening is also used.
Candidate requirements: - PhD or MD/PhD degree obtained within the past 3 years - Demonstrated expertise in cell signaling and molecular biology - Highly self-motivated and creative individual with strong First author publications - Excellent writing and communication skills - Ability to work effectively both independently and as a member of a team is a prerequisite.
Interested applicants should submit their C.V., names of three referees and a statement of research interest to Dr. Hakem ([email protected]).