We are currently seeking highly motivated and independent postdocs to study how oncogenic RAS signaling cooperates with stress stimuli to promote tumorigenesis. The lab has recently described that cancers that are driven by the mutated KRAS gene can mobilize a stress protective response through the engagement of the stress-sensing machinery known as stress granules. The successful candidate will utilize 2D and 3D cell culture, mouse models, high-resolution/high-content microscopy, biochemistry and molecular biology to decipher the molecular networks through which stress granules determine the capacity of mutant KRAS cells to cope with stress, and their role in KRAS-driven pancreatic cancer and the establishment of a tumor-promoting microenvironment. For further information please visit www.grabockalab.com
Candidates should have a recent PhD or MD/PhD degree in cancer biology, cell biology, biochemistry, or a closely related field, have proven ability to work independently as well as within a team, be able to multi-task, and communicate effectively. Only candidates with first author publications from their terminal degree will be considered.
Interested applicants should submit a cover letter explaining their scientific interest, their previous experience, and a CV to Dr. Elda Grabocka at [email protected]. The last page of the CV should include the contact information (e-mail address and phone number) for three references.