Post-Doctoral Training Fellow Biologist - Regulation of HSF1 in cancer cells

The Cancer Research UK Cancer Therapeutics Unit, within the Division of Cancer Therapeutics, is a multidisciplinary 'bench to bedside' centre, comprising around 160 staff dedicated to the discovery and development of novel therapeutics for the treatment of cancer. The Cancer Therapeutics Unit’s exciting goal is to discover high quality drug candidates for validated biological targets and to progress these candidates to clinical trial. All the scientific disciplines are in place to make this possible. Our biologists work alongside world-class chemists and drug metabolism specialists focusing on new molecular targets emerging from human genome and ground breaking cell biology research. This is an exciting and fast moving area of cancer research, and offers the opportunity to work within a multi-disciplinary environment using state-of-the-art techniques and equipment.

We are seeking two highly motivated Biologists to work in our Signal Transduction and Molecular Pharmacology (STMP) Team with Dr Paul Clarke & Professor Paul Workman, located in well-equipped laboratories in Sutton, South London. The successful applicants will use molecular, biochemical and cellular techniques to explore to validate potential molecular targets that regulate the transcriptional response to heat shock and other stresses in cancer cells.

Candidates should possess a PhD in Biochemistry, Molecular Biology or Cell Biology, have developed a range of skills through experience in these areas and be able to work in an interdisciplinary environment towards the goal of performing cellular and biochemical assays required for pathway analysis. Knowledge of cancer research and familiarity with contemporary approaches to drug discovery, molecular target validation is desirable.

Appointment will be to a Post-Doctoral Training Fellowship with starting salary in the range of £30,715 to £39,082 p.a. inclusive (based on previous experience). Appointment will be for 3 years in the first instance, and benefits from a contributory defined benefit pension scheme and generous leave entitlement.

To find more information and to apply online please follow the link to ICR Careers webpage