Generation and characterization of human Bone Organs in mice



    The lab: The successful candidates will be part of the novel laboratory for Cell, Tissue and Organ engineering. The laboratory is part of the Wallenberg Centre for Molecular Medicine (WCMM LU), at the Lund Faculty of Medicine (https://www.med.lu.se/english). Focusing on regenerative medicine (regeneration, replacement and repair), WCMM LU is part of a national effort to strengthen Sweden as a world-leading life science nation (https://www.med.lu.se/wcmm).

    Our lab aims at deciphering the cellular & molecular mechanisms occurring during phases of bone formation/repair. Using state-of-the-art 3D culture systems, death-inducible human mesenchymal lines and tissue engineering protocols, we focus on studying processes of cartilage/bone/bone marrow establishment in human(ized) contexts. Compiled knowledge will be used for the design of cell-based but cell-free extracellular matrices, to be used as smart-materials for skeletal repair. As such, the lab covers both fundamental and translation research aspects.
    More information and example of available projects on: http://www.bourginelab.com/2018/04/12/wanna-collaborate-with-us/

    The University: The lab is located within the BioMedical Center of the Faculty of Medicine and is part of Lund University (Sweden). The university was founded in 1666 and is repeatedly ranked among the world’s top 100 universities. With 42 000 students and 7 400 staff based in Lund, Helsingborg and Malmö, Lund is the second largest university of Sweden.
    The Faculty of Medicine as part of Lund University is responsible for education and research within medicine and healthcare. Our academic programs are closely linked with the healthcare system and are firmly anchored in the faculty’s strong research tradition. Our research spans a broad field within experimental preclinical research, near-patient clinical research and health sciences research. The Faculty of Medicine, is a knowledge-intensive meeting place for students, teachers and researchers from all over the world.

    Keywords: Bone organ, regenerative medicine, tissue engineering, hematopoiesis, 3D culture, stem cells, biological matrices


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