2. >
      3. >

    Generation and characterization of a humanized APOBEC3 mouse: a crucial tool for target validation and preclinical development of APOBEC inhibitors as anti-cancer drugs

    School of Biosciences, University of Kent
    Visit Website
    Back to Results

    We are seeking an experienced and motivated individual to undertake post-doctoral research funded by Cancer Research UK. The project is three years in duration with funding renewed annually subject to satisfactory progress. The lab focusses on the molecular mechanisms underlying cancer development,

    The project will focus on development and characterisation of a novel mouse model for studying a family of deoxycytidine deaminase enzymes (APOBEC3) which have been implicated in generating somatic mutations that drive cancer development and resistance to therapy. This model will serve as a unique tool for fundamental research into APOBEC3 biology and as a preclinical model for the development of APOBEC3 inhibitors as anti-cancer drugs.

    You will be working as part of a dynamic group within the School of Biosciences at the University of Kent and in close collaboration with our co-investigators at Imperial College London, the University of Cambridge and the Institute for Cancer Research. The School offers a supportive and nurturing environment for post-doctoral research.

    The applicant will need a PhD in an appropriate field, and in particular, will need experience working with laboratory mice. They will have the ability to work independently, efficiently, creatively and collegially, and to co-supervise graduate students. They will possess strong written and oral communication skills and be highly self-motivated.
    Visit Website
    Back to Results


    PostDoc Jobs
    Search for PostDocs
    Advertise a PostDoc Jobs
    PostDoc Advice Forum
    Info for advertisers
    Advertise a PostDoc
    Provider Login
    Advertisers T & Cs

    FindAPostDoc. Copyright 2005-2024
    All rights reserved.