Postdoc in Chemical Biology: Customized Cells for the mRNA-instructed Synthesis of Drugs



    We are looking for an excellent and highly motivated postdoc candidate or experienced researcher interested in research on the mRNA-templated generation of peptides and drug-like molecules as gene expression-specific initiators of apoptosis. The research project „TRIGGDRUG (ERC-Advanced Grant)“ includes the establishment of cell lines stably overexpressing cancer-specific mRNA, cell-based assays, and novel approaches for the detection and quantification of mRNA. Therefore, nucleic acid-derivatives (collaborative work with chemists) will be investigated with respect to their specificity/reactivity and will be used for mRNA template-mediated transfer reactions. The project aims for novel approaches for cancer diagnosis and therapy and includes assay development and cell biological studies using modern analytical methods, e.g., fluorescence microscopy. It includes teaching of scientific coworkers and publication of scientific results.
    Project details: http://cordis.europa.eu/project/rcn/198219_en.html
    Working group: https://www.chemie.hu-berlin.de/en/forschung-en/seitz

    Requirements
    University and PhD degree in (chemical) biology/molecular biology/cell biology (preferably with very good results); experience in cell biology and molecular biology (e.g. cloning, ELISA, blotting, stable transfection), ideally experience in fluorescence microscopy and data processing, very good communication and English skills, capability of interdisciplinary work.

    Application:
    Please send your application (including motivation, CV, master and undergraduate transcripts, abstract of the PhD thesis, list of publications) quoting the reference number DR/066/18 to Humboldt-Universität zu Berlin, Faculty of Mathematics and Natural Sciences, Department of Chemistry, Prof. Seitz (Brook-Taylor-Str. 2), Unter den Linden 6, 10099 Berlin, or electronically as a single PDF-file to [email protected]

    Application Deadline: 09.05.2018
    Start: June/July 2018 (third party funding until 31.12.2020), Humboldt Universität Berlin
    Salary: 100% E13 TV-L HU, full time
    Please visit our website www.hu-berlin.de/stellenangebote, which gives you access to the legally binding German version. (https://www.personalabteilung.hu-berlin.de/stellenausschreibungen/wissenschaftlicher-mitarbeiter-m-w-d-mit-vorauss-vollzeit-e-13-tv-l-hu-drittmittelfinanzierung-befristet-bis-31-12-2020)

    Humboldt-Universität is seeking to increase the proportion of women in research and teaching, and specifically encourages qualified female scholars to apply. Severely disabled applicants with equivalent qualifications will be given preferential consideration. People with an immigration background are specifically encouraged to apply. Since we will not return your documents, please submit copies in the application only.


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