The Institute
Research at the Centre for Genomic Regulation (CRG,
www.crg.eu) falls into four main areas: gene regulation, stem cells and cancer; cell and developmental biology; bioinformatics and genomics; and systems biology. Scientists at the CRG have access to state-of-the-art Core Facilities, including genomics, next generation sequencing instruments, bioinformatics, proteomics, super resolution microscopy, FACS, and animal house.
Post Description and Candidate requirements
Pia Cosma’s group is focused on the study of the mechanisms that control somatic cell reprogramming and tissue regeneration. Using super-resolution fluorescence microscopy (stochastic optical reconstruction microscopy; STORM) we have dissected out the nanoscale organization of nucleosome assembly, with high molecular specificity and spatial resolution in a variety of somatic and stem/ reprogrammed cells. We have delineated a novel model of chromatin fiber assembly, and the relationship among the decoded structure and naïve pluripotency (Ricci et al. Cell 2015). More recently we set up powerful imaging approach to visualize genes at nanoscale resolution (Neguembor et al. NAR 2017).
Jérôme Solon’s group is focused on understanding biological control of morphogenesis. The group uses an interdisciplinary approach combining expertise in high-resolution microscopy, image/data processing and analysis and biophysical modelling. The group is developing experimental and analysis methods at multiple scales to understand tissue organization (Saias et al. Dev. Cell. 2015, Czerniak et al. Curr. Biol. 2016), cell shape control (Sumi et al., Dev.Cell. 2018) and nuclear architecture.
Whom would we like to hire?
- You hold a Phd in in physics, mathematics, computer sciences, engineering or related disciplines.
- You have proven experience with data/image analysis, programming and biophysical modeling.
- You are fluent in English
Conditions
The offer is to cover two Postdoctoral positions with a very competitive salary that will be well matched relative to the cost of living in Barcelona.
Starting Date
The fellowship will start as soon as the candidate is hired, ideally by January 2019.
All applications must include:
A cover motivation letter addressed to Dr. Cosma (
[email protected]) and Dr.Solon (
[email protected]) and a full CV with contact details and contacts of 2-3 references.
Please submit your application at:
https://recruitment.crg.eu/content/jobs/position/two-postdoctoral-positions-modelling-and-analysis-super-resolution-imaging/apply
