The Glioma Stem Cell Biology Laboratory at the Meyer Cancer Center at Weill Cornell College of Medicine (formerly Molecular Neuro-Oncology Laboratory of the Neuro-Oncology Branch of the NIH) is a rapidly growing program/laboratory benefitting from exceptional resources, scientific freedom and extraordinary local environment of world-renowned cancer biologists and neuroscientists. Our largest and most rapidly growing area of focus is in the area of tumor stem cell biology and glioma-normal host cell (e.g. astrocytes, neurons) interactions through calcium transits, glutamate, serotonin and other neurotransmitters signaling as studies through the continued development and refinement of a novel “tumor on a chip” technology we have developed using pluripotent cell-derived human cerebral organoids.
A few of our publications that represent the kind of research we do include: Cancer Cell. 9: 287-300, 2006; Cancer Research. 66(19): 9428-36, 2006; Cancer Cell. 9(5):391-403, 2006; Cancer Res. 6(1):21-30, 2008; Cancer Cell 13(1):69-80, 2008; Cell Stem Cell. 4(5): 440-52, 2009.; Cancer Research, 2009; 69(4): 1596-1603, 2009; Cancer Cell.15(4): 247-9, 2009; Cell Stem Cell 4(6): 466-7, 2009; Bioinformatics. 26:1792-3, 2010; Cancer Cell. 18:543-5, 2010;, Cancer Cell 20:695-7, 2011; J. Natl. Cancer Instit. 103:1162-78, 2011; Cancer Cell 21; 710, 2012; Cell Reports 6:313, 2014; Cancer Inform. 2014 Oct 15;13(Suppl 3):33-44. doi: 10.4137; Pharmacogenomics J. 2014 Dec 2. doi: 10.1038/tpj.2014.61; Int J Cancer. 2017 Jul 14. doi: 10.1002/ijc.30887; Sci Rep. 2017 Mar 3;7:43605. doi: 10.1038/srep4360
The laboratory allows outstanding exposure to and potential involvement in all aspects of translational science while exploring basic mechanistic studies of tumorigenesis using a combination of molecular and computational biology approaches.
Please email a letter of interest, curriculum vitae and list of three references to Howard A. Fine, M.D. at;
[email protected]
