We are currently seeking two highly motivated and talented post-doctoral research scientists to help establish a new translational immunology laboratory at the School of Veterinary Medicine (Penn Vet) of the University of Pennsylvania, continuing the work of a well-established principal investigator who has relocated to Penn Vet.
You will work within the Immune Regulation Laboratory on an outstanding project examining the cellular and molecular phenotype, pathogenic role, and functional interactions of regulatory T cells and myeloid-derived suppressor cells in canine cancer or autoimmune disease (according to your expertise). We propose to extend our previous research in the area of peripheral tolerance in canine cancer and canine autoimmune disease, with the aim of advancing it into the clinical arena to develop novel immune therapies. Our emphasis is on One Health, One Medicine, using spontaneous canine disease for both its veterinary importance and its unique ability to model equivalent human diseases. Our work will also require the use of murine models.
These exciting posts would suit post-doctoral scientists with a passion for immunological research and a keen drive to generate publishable data and, in time, to submit a fellowship application. You will enjoy the pace of a rapidly advancing and competitive field that incorporates both regulatory cell and cancer / autoimmune disease biology, while working in a team-centered, supportive and friendly laboratory within an excellent research institution, based in one of America’s most vibrant, exciting metropolitan hubs. In addition, our laboratory actively participates in the Immunology Graduate Group (
http://www.med.upenn.edu/immun/) and the Institute for Immunology (
http://www.med.upenn.edu/ifi/) of the University of Pennsylvania.
Qualifications
1. We are looking for enthusiastic, driven individuals who have strong experience and skills in protein analysis (multicolor flow cytometry, Western blot, immunohistochemistry / immunofluorescence, ELISA), primary cell culture, molecular biology (cloning, mutagenesis, transcriptional analysis, isolation of mRNA and its analysis, plasmid and lentivirus preparation and gene transfer), and animal work. A veterinary qualification is not a pre-requisite.
2. Willingness to receive clinical samples for immunophenotyping by flow cytometry and research purposes, involving evening and weekend work as needed
3. Computer literacy, including the ability to use a variety of software packages to analyze data
4. A strong publication track record
5. Strong communication and team-playing skills, a detail-oriented mind-set, and the ability to work independently in a collaborative setting
Salary and benefits
Your salary will be based upon the NIH salary structure for post-doctoral scientists. Health benefits will be provided and are outlined on the website for the Biomedical Post-Doctoral Program (
https://www.med.upenn.edu/postdoc/policies.shtml). This post will be a one-year appointment in the first instance, with annual reappointment for a maximum of five years based upon adequate performance reviews.
Contact
Applications should include:
1. A Curriculum Vitae
2. A notarized copy of a diploma, or a notarized statement from the registrar or University official that you have received your doctoral degree and completed all degree requirements
3. A list of publications
4. A cover letter indicating research interests and career goals of no more than 600 words
5. The names and contact details of four academic referees
Please submit all of your application materials in one email to Ms Denise Danner at
[email protected], clearly indicating your name and the words Postdoc Scientist in the Subject header. Informal inquiries should be directed to Dr Oliver Garden (The Henry and Corinne R Bower Professor of Medicine, and Chair of the Department of Clinical Studies - Philadelphia) on
[email protected].
