MRC Postdoctoral Research Scientist
Steroid Metabolism
(3 Year fixed term)
MRC Band 4 Salary: £37,500 plus London allowances (£3,727 & £1,402) per annum*
London, UK
MRC Laboratory of Medical Sciences (LMS)
https://lms.mrc.ac.uk/ is a world-class research laboratory where scientists and clinicians collaborate to advance the understanding of biology and its application to medicine. Funded by the MRC as part of UK Research and Innovation, the LMS has a collaborative working culture and new state-of-the-art building based in the heart of West London in the Hammersmith Hospital Campus (W12).
The LMS aims to deliver transdisciplinary team science, in synergistic interaction with Imperial College and the wider national research environment. Part of achieving this, is to recruit new talent and support postdoctoral scientists to become world leaders in their area of science.
A 3-year postdoctoral position is available at the MRC Laboratory of Medical Sciences (LMS) to work in the Steroids and Metabolism group headed by Prof. Wiebke Arlt. The LMS is a world-class research laboratory where scientists and clinicians collaborate to advance the understanding of biology and its application to medicine. Funded by the MRC as part of UK Research and Innovation, the LMS has a collaborative working culture and new state-of-the-art building based in the heart of West London in the Hammersmith Hospital Campus.
The Steroids and Metabolism Group, headed by Professor Wiebke Arlt, explores how steroid metabolism and function influences human physiology and health. Our current focus is on the investigation of the mechanisms that link steroids to human metabolic dysfunction and disease including sex differences in the metabolic response to androgens.
We use a range of human in vivo, ex vivo and in vitro model systems and routinely use mass spectrometry for the exploration of the steroid metabolome, often in conjunction with machine learning approaches. Our lab features two state-of-the-art liquid chromatography-tandem mass spectrometry platforms (Xevo TQ-XS).
We are looking for a self-motivated researcher with a background in analytical chemistry, systems biology or a related biomedical field. The candidate should have a record of accomplishments indicating the ability to perform analysis, visualisation, and dissemination of multi-metabolite data produced by mass spectrometry and experience with tandem mass spectrometry method development and validation.
Applicants should have a track record of original research including at least one first author publication in a respected journal. Previous experience in metabolism and metabolomics (steroid and endocrinology), biochemical techniques, including in vitro enzyme assays and proteomics would be an advantage. The successful candidate will work in a focused and organized manner to produce independent research, deliver the scientific aims of the project and aid in the submission of publications to referred journals. They will supervise students, interact with computational scientists embedded in the group and contribute to research group outputs by writing abstracts, conference presentations, original research manuscripts, review articles and contribute to grant proposals.
For full details of this post and to complete an online application, visit MRC Postdoctoral Research Scientist LMS 2283 - Medical Research Council (tal.net)and upload your CV, names and contacts of two scientific references along with a covering letter stating why you are applying for this role (providing evidence against the requirements of the job as per the job description and person specification). Please quote reference number LMS 2283.
Closing date: 3 December 2023
This role qualifies for endorsement by UKRI for a UK Global Talent Visa, for which the successful applicant is likely to be eligible to apply.
‘The MRC is an equal opportunities employer.
‘Leading Science for Better Health’
Final appointment will be subject to pre-employment screening
*Additional allowances comprise a £1,000 lump sum Settlement Allowance plus a yearly Training Allowance of £850 in the first year, paid in monthly installments.
The Training Allowance increases to £1,300 in year two, and £1,800 in the third year.
