Postdoctoral Research Associate in Molecular Imaging

    • Application Deadline
      22 March 2023
      (application date has expired)
    • Job Salary
      £40,386 to £47,414 Including London weighting
    • Website
    • Contact Name
      Dr Tim Witney

    We are seeking an enthusiastic, proactive, and collaborative biologist to join Dr Witney’s Group in the School of Biomedical Engineering & Imaging Sciences, King’s College London. You will join a dynamic and successful molecular imaging Team with access to both cutting-edge instrumentation for preclinical imaging and world-renowned expertise. Together, we are developing next-generation whole-body imaging tools for cancer diagnosis, monitoring of therapeutic response, and detection of drug resistance (see for more details).

    Working in collaboration with medicinal chemists and radiochemists, the successful candidate will use radionuclide-based molecular imaging and radionuclide therapy for the detection and treatment of drug-resistant cancer (‘theranostics’). We have successfully developed a library of theranostic agents that selectively target biomarkers of treatment failure. You will lead the biological evaluation for one of our theranostics programmes using a range of advanced mouse models of cancer (syngeneic, genetically engineered and patient-derived). The project will use molecular biology, protein biochemistry, and enzyme assays to further characterise these agents and understand their mechanism of action. You will further optimise radionuclide therapy scheduling to exploit the vulnerabilities of drug-resistant cancer. Support will be provided for you to take the project in new and interesting directions.

    You will manage your own research and administrative activities, within guidelines provided by the PI and in collaboration with senior colleagues, and contribute to wider project development and potential commercialisation. You will determine the most appropriate methodologies to test hypotheses and identify suitable alternatives if technical problems arise, as well as select, follow, and present scientific data from a variety of sources. You will contribute to discussions and share research findings with colleagues in partner institutions, and research groups.

    You must have a track record of research achievement (through peer-reviewed publications) and hold a PhD in cancer biology, biochemistry, molecular imaging, or similar. Experience with small animal imaging and radioactivity handling is necessary. We are dedicated to supporting the successful candidate’s career through assistance with Fellowship applications, networking events, and attendance at international conferences.

    This post will be offered on an a fixed-term contract to 28 February 2026
    This is a full-time post - 100% full time equivalent

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