Cell Biology of Liver Metabolism (m/f/x) 101294
Helmholtz Zentrum München
Helmholtz Zentrum München is a research center with the mission to discover personalized medical solutions for the prevention and therapy of environmentally triggered diseases and promote a healthier society in a rapidly changing world.
Obesity and diabetes have become epidemic over the last 20 years. Although lots of knowledge has been collected regarding the pathogenesis of these diseases, the intracellular regulatory mechanisms are still not resolved. The group of Anja Zeigerer, located at the Institute for Diabetes and Cancer, investigates the role of membrane trafficking in metabolic homeostasis. The lab is seeking to the next possible time point a highly motivated
to investigate the function of Rab GTPase in mitochondrial fission and protein secretion during the fasting / feeding transition in the liver. This project is part of collaborative effort with the Munich Cluster of Systems Neurology headed by Prof. Christian Behrends at the Ludwig-Maximilians-University (LMU) Munich.
-Planning and realization of experimental studies in the areas of cell biology and membrane trafficking with connection to liver physiology of fasting and feeding Biochemical, cell biological and immunofluorescence analysis of cell and tissue samples.
-Primary cell culture of murine and human hepatocytes and analysis of tissues from different mouse models to investigate their contribution to the fasting / feeding switch
-“Omics” data analysis, graphical documentation, and evaluation for conferences, scientific publications, and reports
-PhD or equivalent level of professional qualification in biochemistry or cell biology
-Strong theoretical and practical background on intracellular membrane trafficking required
Experience with complex methods in molecular biology and biochemistry
-Knowledge in hepatocellular metabolism and physiology are a plus
-Experience in primary cell culture, imaging, and mouse work
-High motivation, flexibility, as well as innovate and creative thinking are a must
-A strong academic record, international experience, and proficiency in English are required
What we offer you
-Continuous education and training
-Flexible working hours & time off in lieu
-30 days annual leave
-On-site health management service
-Company pension scheme
-Discounted public transport ticket
Munich, with its numerous lakes and its vicinity to the Alps, is considered to be one of the cities with the best quality of life worldwide. With its first-class universities and world-leading research institutions it offers an intellectually stimulating environment.
Remuneration and social benefits are based on the collective wage agreement for public-sector employees at federal level (TV EntgO Bund). The position is (initially) limited to three years, but under certain circumstances an extension can be arranged.
To promote diversity, we welcome applications from talented people regardless of cultural background, nationality, ethnicity, gender and sexual identity, physical abilities, religion, and age. Qualified applicants with physical disabilities will be given preference.
If you have obtained a university degree abroad, we require further documents from you regarding the recognition of the degree. Please request the recognition as early as possible.
If you have further questions, simply contact Miriam Guhl, +49 89 3187-1046, and Anja Zeigerer, +49 89 3187-1048, who will be happy to be of assistance.
Please upload your online application including a cover letter, detailed CV, copies of your certificates, as well as at least two letters of recommendation.
Helmholtz Zentrum München
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Institute for Diabetes and Cancer
Ingolstädter Landstraße 1
Award for excellent gender equality policy for women and men. Helmholtz Zentrum München is particularly committed to promoting professional equality between women and men. It therefore aims to increase the proportion of the underrepresented sex in the respective field.
The Helmholtz Zentrum München is part of the Helmholtz Association, Germany’s largest scientific organization. Altogether 42,000 people currently work in its 19 scientific-technical and biological-medical research centers. The Association’s annual budget amounts to around 5 billion euros.