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Postdoctoral Scientist - Neurobiology - Dr Anne Bertolotti - LMB 1718



Postdoctoral Scientist/ Career Development Fellow
Salary Range £32,302 - £35,143 per annum
Fixed term, 3 years
MRC Laboratory of Molecular Biology, Cambridge, UK

The MRC Laboratory of Molecular Biology is a world leader in biological research, with an expanding scientific programme dedicated to understanding gene function in health and disease. It provides an unsurpassed environment for both young and established researchers. Scientists are drawn to the LMB from all over the world, creating a lively and international community for the exchange of ideas and technical innovation.

The position is for a molecular and cell biologist with expertise and track record on signaling.

You will join Dr Anne Bertolotti’s pioneering research programme, which focuses on innovative approaches to rescue cells from protein misfolding, a condition at the origin of many human diseases, including neurodegenerative diseases. One of such approaches consists in targeting eIF2a phosphatases to boost protein quality control capacity (see Tsaytler et al., 2011, Science, 332, 91-4; and Das et al., 2015, Science, 348, 239-242, Carrara, M., Sigurdardottir, A., & Bertolotti, A. (2017). Nat Struct Mol Biol, 24(9), 708–716). Krzyzosiak, A., Sigurdardottir, A. et al., A. (2018). Cell, 174(5), 1216–1228.e19; Schneider K. et al., (2020), Sep 15;32(11):108154, Cell Reports)

You will join a strong inter-disciplinary team at the LMB, which has broad expertise extending from biochemistry, structural, chemical, molecular and cell biology through to transgenic animal models of degenerative diseases. The team also has an excellent record of innovative basic research leading to applications in medicine.

Further information about the position may be obtained from Dr Anne Bertolotti– email: [email protected]

You will be ambitious, creative and fearless. You will have a PhD molecular or cell biology or due to complete doctoral studies within 6 months of applying. Relevant molecular and cell biology experience is required and this must be best attested by at least one impactful publication. Interests in stress responses and/or neurodegenerative diseases is desirable. It is also essential to have significant publications in this area.

You will enjoy interacting with a dynamic interdisciplinary team sharing a passion for science and a commitment to explore the unknown.

The successful applicant will be awarded a 3-year Career Development Fellowship/ Postdoctoral Training Scheme position. This is a training and development position for a Postdoctoral Scientist who has recently completed their doctoral studies, is moving into a new research discipline or has limited experience of key transferable skills. The MRC LMB has excellent scientific core facilities and training opportunities.

The MRC Laboratory of Molecular Biology is a research institute within UK Research and Innovation (UKRI). UKRI is an entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at www.ukri.org.

Working for UKRI MRC provides a whole host of benefits including a defined benefit pension scheme, excellent holiday entitlement (40 ½ days including bank holidays and privilege days) and Benenden Healthcare membership. You will also have access to employee shopping/ travel discounts, on site sport and social facilities, as well as salary sacrifice cycle to work schemes and childcare vouchers.
This role qualifies for endorsement by UKRI for a UK Global Talent Visa, for which the successful applicant is likely to be eligible to apply. Immigration costs (visa and health surcharge) can be reclaimed from UKRI after taking up the post (terms and conditions apply).

Closing date: 07/12/2021

Final appointments will be subject to a pre-employment screening.
The Medical Research Council is an Equal Opportunities Employer who participates in the Disability Confident scheme.


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