Infection and Immunity
In order to invade the host cell apicomplexan parasites evolved a whole set of unique organelles that are linked to the secretory pathway of the parasite. Surprisingly these parasites have only a limited set of trafficking factors. The laboratory aims to systematically investigate the vesicular trafficking system using reverse and forward genetic approaches, combined with cutting edge imaging technologies.
Representative publications from our research group include:
Breinich M. et al., 2009 Current Biology. 19(4):277-86, Agop-Nersesian C. et al 2009 PLOS Pathogens., 5(1):e1000270 ,Kessler, H. et al., (2008). Journal of Cell Science, 121, 947-56, Herm-Götz,A.*,et al. (2007) Nature Methods 4,1003-5
We are seeking highly motivated, curious and enthusiastic individuals with excellent problem solving skills to thrive in a highly supportive environment. The ideal candidate will have outstanding molecular and cell biology training. Experience in modern microscopic techniques (live cell imaging, FRET, FRAP) and biochemical techniques (Co-purifications, development of in vitro assays, etc.) will be appreciated. Previous experience with apicomplexan parasites is not mandatory. The position should appeal most to scientists who want to apply cutting edge genetics and imaging techniques to the study of vesicular trafficking in an unconventional eukaryote that evolved unique organelles in order to adapt to a parasitic life style. Ref: 00152-1
The duration of the appointment will be dependent on the salary placing at appointment – up to 5 years.
Apply online at www.glasgow.ac.uk/jobs
|
